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The Effect of Low-Frequency Repetitive Transcranial Magnetic Stimulation on Treatment-Resistant Tourette's Syndrome among Children and Adolescents : An Open-Label Study (치료저항성 뚜렛장애를 가진 소아청소년에서 저빈도 반복적 경두개자기자극술의 효과 : 오픈 라벨 연구)

  • Lee, Young-Ji;Chae, Jin Hyuk;Seo, Wan Seok
    • Journal of the Korean society of biological therapies in psychiatry
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    • v.24 no.3
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    • pp.239-246
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    • 2018
  • 목 적 : 본 연구의 목적은 치료저항성 뚜렛장애를 가진 소아 청소년들에 대해서 보조운동영역을 표적으로 한 저빈도 반복적 경두개자기자극술의 효과를 평가하는 것이다. 방 법 : 이 연구는 미국정신의학회 진단기준 및 통계편람, 제 4판을 기준으로 뚜렛장애로 진단받은 10명의 소아 청소년(평균연령 $12.56{\pm}1.04$세)을 대상으로 하였다. 모든 참가자들은 1년 이상 지속적으로 충분한 용량의 약물치료를 받았음에도 불구하고 한국판 예일 틱 증상 평가척도(YGTSS) 20점 이상, 임상인상척도(CGI-TS) 4점 이상을 받았다. 참가자들은 보조운동영역을 표적으로 1 Hz 반복적 경두개자기자극 치료를 매일 20분간 받았으며, 총 20회 치료를 받았다. YGTSS, CGI-TS 및 이상반응 체크리스트는 연구 시작 전과 연구 시작 후 4, 8, 12주에 시행되었다. 결 과 : 틱 증상은 연구 12주차까지 호전된 상태로 지속되었으며, YGTSS와 CGI-TS가 통계적으로 유의하게 감소하였다. 특히 음성 틱 점수의 감소가 운동 틱 점수의 변화보다 전체 YGTSS 점수의 감소에 큰 역할을 한 것으로 나타났다. 그리고 전체 10명의 참가자 중 9명이 심각한 부작용 없이 연구를 끝까지 완료하였다. 결 론 : 본 연구는 보조운동영역을 표적으로 한 저빈도 반복적 경두개자기자극술이 치료 저항성 뚜렛장애를 가진 소아 청소년들에게 효과적이고 안전한 치료도구가 될 수 있음을 시사한다. 이러한 반복적 경두개자기자극술의 치료효과를 확정하기 위해서는 보다 많은 환자를 대상으로 한 잘 통제된 연구가 필요할 것이다.

The Treatment of Humerus Shaft Simple Fracture by MIPO Technique (상완골 간부 단순 골절에서 최소 침습적 금속판 골유합술을 이용한 치료)

  • Ko, Sang-Hun;Lee, Sun-Ho;Cho, Bum-Keun
    • Clinics in Shoulder and Elbow
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    • v.16 no.1
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    • pp.27-32
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    • 2013
  • Purpose: The purpose of this study is to evaluate the clinical and radiological outcomes of treatment of humerus shaft simple fracture by minimally invasive percutaneous osteosynthesis (MIPO) technique using locking compression plate (LCP). Materials and Methods: Six patients who were operated for humerus shaft simple fracture from August 2010 to May 2011 were enrolled for this study. We checked the cause of injury and the accompanying injuries and evaluated the operation time, the clinical and radiological period of union, postoperative range of motion of the shoulder and elbow joint, pain, activities in daily living, radiologic alignment, and other complications. Results: The clinical period of bone union was 7.2 weeks on average, and the radiologic period of bone union was 8 weeks on average. Follow-up period was more than 12 months in all cases. The angulation through postoperative alignment was 2.8 degrees in AP view and 2 degrees in lateral view. The postoperative range of motion was 167 degrees in forward flexion, 50 degrees in external rotation, and thoracic vertebra 12 level in internal rotation. The average value of visual analogue scale (VAS) was 1.2 and that of KSS was 91.3. The American Shoulder and Elbow Surgeons' score (ASES) was 26.5 and the UCLA score was 31.5. Conclusion: MIPO technique for the humerus shaft simple fracture showed good functional and radiological outcomes and may be considered as one of the treatment options for humerus shaft simple fracture.

Treatment of Distal Clavicular Fracture by Reconstruction Plate and Wire Fixation (쇄골 원위부 골절에 대한 재건 금속판과 강선 고정술을 이용한 치료)

  • Suh, Mu-Sam;Kim, Sang-Hyo;Park, Hyeong-Taek
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.5 no.1
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    • pp.58-62
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    • 2006
  • Purpose: To evaluate the result of operative treatment with plate and wire fixation for fractures of the distal clavicle. Materials and Methods: We assessed 9 cases of fractures of the distal clavicle that were treated by plate and wire fixation from March 2001 to July 2003 and followed up over 1year. We used the reconstruction plate as a buttress and performed cerclage wiring to fix comminuted fracture site. The functional result of shoulder was evaluated by the scoring system of Rowe. Results: The average periods of bony union was 9 weeks in all cases. According to Rowe scoring system, the functional result was exellent in 7 cases and good in 2 cases. There was no LOM of shoulder and traumatic arthritis in AC joint. But there was skin irritation in 1 case. Conclusion : The operative method by reconstruction plate and wire fixation for distal clavicular fracture was useful when there were comminuted fracture. This method seems to be simple and satisfactory in terms of improvement of range of motion of shoulder, restoration of function and rare complication.

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The Volar Plating of Fracture of the Coronoid Process - Report of Two Cases - (구상돌기 골절에서 내측 접근법을 통한 전방 금속판 고정술 - 2예 보고 -)

  • Jung, Gu-Hee;Cho, Chul-Hyun;Jang, Jae-Ho;Kim, Jae-Do
    • Clinics in Shoulder and Elbow
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    • v.13 no.2
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    • pp.260-265
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    • 2010
  • Purpose: To report the clinical results of two cases of coronoid process fractures that were treated with volar plating through a medial approach. Materials and Methods: Two fractures of the coronoid process that needed to be fixed were managed with open reduction and internal fixation through a medial approach using 2.4 mm locking compression plates (Compact Hand set$^{(R)}$, Synthes, Switzerland). The patients were followed up for 14 months and 17 months and were evaluated using the Mayo Elbow Performance Score (MEPS). Results: The MEPS was 95 for Case 1 and 100 for Case 2. Active elbow joint motions were $5^{\circ}-120^{\circ}$ (Case 1) and $0^{\circ}-130^{\circ}$ (Case 2). Supination and pronation fully recovered. Conclusion: Satisfactory results can be obtained in cases of coronoid process fractures because volar plating through a medial approach allows sound fixation and early mobilization of the elbow joint.

An Experimental Study for the Heat Transfer Augmentation of an Impinging Jet (충돌 분류의 열전달 특성향상을 위한 실험적 연구)

  • 정기호;김예용;김귀순
    • Journal of the Korean Society of Propulsion Engineers
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    • v.3 no.2
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    • pp.66-74
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    • 1999
  • In this study, the heat transfer augmentation without additional blower power was obtained by using punched plate. Though this scheme has some disadvantages such as decrease of momentum caused by the punched plate, it has significantly increased heat transfer coefficients in the stagnation region. Compared with the case of no punched plate, heat transfer coefficients were increased by punched plate more than 2 times near the optimum condition determined in this study. Liquid crystal and hue-capturing technique were used in this study to obtain heat transfer coefficients.

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Experimental and Numerical Study for Motion Reduction Design of Floating Wave Energy Converter (부유식 파력발전구조물의 운동 저감부 형상설계에 관한 수치 및 실험적 연구)

  • Park, Ji Yong;Nam, Bo Woo;Hong, Sa Young;Shin, Seung Ho
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.17 no.2
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    • pp.81-89
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    • 2014
  • The present study aims to design an optimized hull shape of a floating pendulum-type wave energy converter(WEC). The purpose of these structure is to improve the performance and stability of the WEC by reducing its motion under operating and survival wave conditions. In this study, motion reduction structures, like restoring and dampling plates were installed on a floating pendulum WEC that has been the subject of previous studies. Restoring plates were installed to increase the restoring force and shift the natural period to a shorter period. Damping plates were installed to shift the natural period to a longer period by increasing the added mass. The effects of the structures were then analyzed under different incident wave conditions. The design parameters for the motion reduction structures were size, shape, and installed position. The wave-induced motion characteristics and performance of the floating pendulum WEC were also investigated numerically. Based on the simulation results, we are able to optimize the motion reduction structure of the WEC, thus improving its efficiency and durability.

한반도 지진 위험 진단과 연구 실태

  • Kim, So-Gu
    • The Science & Technology
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    • v.30 no.3 s.334
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    • pp.55-61
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    • 1997
  • 최근 한반도 주변인 중국과 일본 및 사할린에서 일어난 대지진은 충격적이다. 이것은 한반도를 중심으로 인접한 여러판의 새로운 지체구조력 운동이 활발하다는 것을 증명해준다. 지진이 발생할 때 신속ㆍ정확한 정보를 제공하여 응급 대피할 수 있도록 하는 연구와 대책이 절실하다.

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당뇨병관리, 소아에서 노인까지- 소아당뇨인을 위한 식사요법

  • Gang, Yeon-Ha
    • The Monthly Diabetes
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    • s.192
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    • pp.12-16
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    • 2005
  • 소아 당뇨병은 성인 당뇨병의 축소판이 아니며 성장과 발육을 고려하여야 하고 성장에 따른 지속적인 추구관리가 이루어져야 한다는 점이 중요하다. 또한 아동들의 식욕을 조절하며 간식과 외식, 추가 운동, 여행, 생일 파티 참석 등 발생될 수 있는 특별한 경우에는 상황에 맞춰 혈당조절을 해야 한다.

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