• Title/Summary/Keyword: 용적분석

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Analysis of the major factors of influence on the conditions of the Intensity Modulated Radiation Therapy planning optimization in Head and Neck (두경부 세기견조방사선치료계획 최적화 조건에서 주요 인자들의 영향 분석)

  • Kim, Dae Sup;Lee, Woo Seok;Yoon, In Ha;Back, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.1
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    • pp.11-19
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    • 2014
  • Purpose : To derive the most appropriate factors by considering the effects of the major factors when applied to the optimization algorithm, thereby aiding the effective designing of a ideal treatment plan. Materials and Methods : The eclipse treatment planning system(Eclipse 10.0, Varian, USA) was used in this study. The PBC (Pencil Beam Convolution) algorithm was used for dose calculation, and the DVO (Dose Volume Optimizer 10.0.28) Optimization algorithm was used for intensity modulated radiation therapy. The experimental group consists of patients receiving intensity modulated radiation therapy for the head and neck cancer and dose prescription to two planned target volume was 2.2 Gy and 2.0 Gy simultaneously. Treatment plan was done with inverse dose calculation methods utilizing 6 MV beam and 7 fields. The optimal algorithm parameter of the established plan was selected based on volume dose-priority(Constrain), dose fluence smooth value and the impact of the treatment plan was analyzed according to the variation of each factors. Volume dose-priority determines the reference conditions and the optimization process was carried out under the condition using same ratio, but different absolute values. We evaluated the surrounding normal organs of treatment volume according to the changing conditions of the absolute values of the volume dose-priority. Dose fluence smooth value was applied by simply changing the reference conditions (absolute value) and by changing the related volume dose-priority. The treatment plan was evaluated using Conformal Index, Paddick's Conformal Index, Homogeneity Index and the average dose of each organs. Results : When the volume dose-priority values were directly proportioned by changing the absolute values, the CI values were found to be different. However PCI was $1.299{\pm}0.006$ and HI was $1.095{\pm}0.004$ while D5%/D95% was $1.090{\pm}1.011$. The impact on the prescribed dose were similar. The average dose of parotid gland decreased to 67.4, 50.3, 51.2, 47.1 Gy when the absolute values of the volume dose-priority increased by 40,60,70,90. When the dose smooth strength from each treatment plan was increased, PCI value increased to $1.338{\pm}0.006$. Conclusion : The optimization algorithm was more influenced by the ratio of each condition than the absolute value of volume dose-priority. If the same ratio was maintained, similar treatment plan was established even if the absolute values were different. Volume dose-priority of the treatment volume should be more than 50% of the normal organ volume dose-priority in order to achieve a successful treatment plan. Dose fluence smooth value should increase or decrease proportional to the volume dose-priority. Volume dose-priority is not enough to satisfy the conditions when the absolute value are applied solely.

Effects of Bulk Density, Volumetric Water and Gravel Contents on Hardness in Prepared Sandy Loam (충전(充塡) 사양토(砂壤土)에서 용적밀도(容積密度), 용적수분(容積水分) 및 자갈함량(含量)이 경도(硬度)에 미치는 영향(影響))

  • Cho, Jae-Hyun;Kim, Kwang-Rai
    • Korean Journal of Soil Science and Fertilizer
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    • v.30 no.1
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    • pp.46-50
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    • 1997
  • This study was conducted to find out the main soil physical properties to control the soil hardness in tamped condition. Sandy loam soil was taken and fill it up to wood cubes and then differently trampling experimental cubic lots which were mulched with various materials, such as, leaves, wood plates and bricks. Soil physical properties were measured 2" core and samples were taken at 250 sites with soil hardness. There were highly significant positive correlations between soil hardness and bulk density, and between bulk density and water content. Negative correlations were found between soil hardness and water content, and between soil hardness and gravel content. The correlation coefficients were increased by multiple correlation between soil hardness, bulk density, volumetric water and gravel content. Bulk density was the main factor to control the hardness, and volumetric water and gravel contents were less effected to soil hardness.

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The Correlation Analysis of Ejection Fraction: Comparison of $^{201}Tl$ gated Myocardial Perfusion SPECT and Echocardiography ($^{201}Tl$ 게이트 심근관류 SPECT 및 심초음파의 좌심실 구혈률 상관관계 비교)

  • Yoon, Soon Sang;Ryu, Jae Kwang;Cha, Min Kyung;Lee, Jong Hun;Kim, Sung Hwan
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.49-56
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    • 2012
  • Purpose : Gated myocardial perfusion SPECT provides not only myocardial perfusion status, but various functional parameters of left ventricle (LV). The purpose of this study was to analyze ejection fraction (EF) for correlation and difference between $^{201}Tl$ gated myocardial perfusion SPECT and echocardiography depending on extent of perfusion defect, gender and LV volumes. Materials and Methods : From April 2011 to May 2012, we analyzed 291 patients (male:female =165:126; mean: $64.6{\pm}10.8$ years) who were examined both $^{201}Tl$ gated myocardial perfusion SPECT and echocardiography at less than 7 days apart in our hospital. 101 patients showed perfusion defect and the rest of the people without any defect. We applied automatic analysis (Quantitative gated SPECT, QGS), and calculated EF, End-diastolic volume (EDV) and End-systolic volume (ESV) from Stress (G-Stress) and Rest (G-Rest) studies. And we analyzed the correlation and difference for EF between $^{201}Tl$ gated SPECT and echocardiography. Results : The correlation of LVEF among G-Stress, G-Rest and echocardiography was quite a good (G-Stress vs. G-Rest: r=0.909, G-Stress vs. echocardiography: r=0.833, G-Rest vs. echocardiography: r=0.825). And there were significant differences in EDV, ESV and EF in total patients (p<0.01). The normal group showed significant difference in EF (p<0.01) and the group with perfusion defect also demonstrated significant difference (a group with reversible defect: p<0.01, fixed defect: p<0.01) depending on extent of perfusion defect. We analyzed difference in normal group by gender. In normal group, there was no significant difference (p>0.05) in EF from men. However, there was a significant difference (p<0.01) from women. When we classified two groups by average size of EDV in Korean women, there was no significant difference in a group of above average size of EDV (p>0.05). Conclusion : When compared among Stress and Rest of $^{201}Tl$ gated SPECT and echocardiography, we confirmed that there was a good correlation for LVEF. But there were significant differences among three studies. And extent of perfusion defect, gender and LV volumes are independent determinants of the accuracy of LVEF. So, it is hard to compare and interchange quantitative indices among modalities. We should take additional researches to prove results of our study.

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Growth Performance of Sedum reflexum and Physical Properties of Extensive Green Roof Growing Media (경량형 옥상녹화 식재기반의 물리성과 레플렉숨 생육특성)

  • Li, Hong;Kang, Tai-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.6
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    • pp.50-59
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    • 2014
  • This experiment was performed in order to study the relationship between physical properties of soil and the growth characteristics of Sedum reflexum. A correlation analysis and multiple regression analysis were performed using SPSS Ver 19.0 for Windows. The multiple regression analysis results of soil physical properties and growth characteristics were as follows. The regression equation: The length=$.993-14.070^*$(soil bulk density)+$.233^*$(solid phase)+$.038^*$(liquid phase)+$.068^*$(permeability). The significance of soil bulk density and solid phase was great. The width=$2.931-33.925^*$(soil bulk density)+$.566^*$(solid phase)+$.206^*$(liquid phase)+$.027^*$(permeability). The significance of soil bulk density and solid phase was great. The wet weight and dry weight of the upper and lower and soil physical properties did not have a direct relationship.

Correlation Between Left Ventricular Peak Systolic Pressure/End-Systolic Volume Ratio and Symptomatic Improvement with Valve Replacement in Patients with Aortic Regurgitation and Enlarged End-Systolic Volume (대동맥판역류증과 좌심실수축말기용적 확장이 있는 환자에서 좌심실최고수축기압/수축말기용적비와 판막치환후의 증상적 호전과의 관계)

  • Kim, Woong-Han;Ahn, Hyuk
    • Journal of Chest Surgery
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    • v.29 no.8
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    • pp.867-874
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    • 1996
  • This study was designed to assess the left ventricular peak systolic pressure/end-systolic volume (PSP/ESV) ratio in predicting symptomatic improvement with valve replacement in patients with aortic regurgitation and enlarged left von'lrlcular volume. We studied 21 patients (15 men and 6 women aged 15 to 60 years) with moderate or severe aortic regur- gitation, no other cardiovascular abnormalities and left ventricular end-systolic volume over 60 m11m2. In this group we assessed the preoperative variables which routinely were measured at cardiac catheterlzation to predict symptomatic improvement with valve replacement. Six months after operation, symptoms were alleviated in 13 patients(62%), and unchanged in 8()8%). By multivariate analysis, the PSP/ESV rati was a strong predictor for functional class 6 months after surgery(p=0.005) and also for change- in functional class prior to an operation to 6 months postoperatively(p=0.0)2). By 6 months after receiving valve replacement, all patients with a ratio over 1. 71 mmHglml/m'were in functional class I or II , in contrast, of those with a ratio < 1.71 mmHg/ml/m2, 40% were in functional class III. The PSP/ESV ratio may help to predict which patients with aortic regurgitation and enlarged left ven- tricular end-systolic volume will have symptomatic improvement with valve replacement.

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A Comparative Study of Radiation Therapy Planning between Volumetric-Modulated Arc Therapy and Three-Dimensional Conformal Radiotherapy in Nasopharyngeal Cancer (비인두암의 방사선치료 시 삼차원입체조형 치료기법과 용적세기조절회전치료기법의 비교연구)

  • Kim, Ji-Sung;Lee, Seok-Ho;Lee, Seung-Heon;Kim, Hye-Young;Choi, Jin-Ho;Lee, Kyu-Chan;Kim, Dong-Young
    • Korean Journal of Head & Neck Oncology
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    • v.26 no.2
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    • pp.171-177
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    • 2010
  • 연구목적 : 비인두암 환자들을 대상으로 방사선치료 시 삼차원입체조형치료기법과 용적세기조절회전치료기법을 비교하고 이하선을 포함한 정상조직 보호에 있어 그 차이점을 알아 보고자 본 연구를 시행하였다. 대상 및 방법 : 비인두암 환자 5명을 대상으로 치료계획용 CT(computed tomography)를 시행 후 삼차원입체조형방사선치료계획 과 용적세기조절회전치료계획을 시행하였다. 이를 바탕으로 얻은 선량분포, conformity index(CI) 그리고 선량체적 히스토그램을 통해 손상위험장기(organ at risk)와 계획용표적체적(planning target volume)을 비교 분석하였다. 결 과 : 분석결과 이하선에 조사되는 평균선량이 용적세기조절회전치료계획에서는 43.9%로 삼차원입체조형치료계획에서의 89.4% 보다 유의하게(p=0.043) 감소하였다. 계획용표적체적 conformity index의 경우 용적세기조절회전치료계획 (CI=1.06)에서 삼차원입체조형치료계획(CI=2.55) 보다 유의하게(p=0.043) 향상된 결과를 보였다. 결 론 : 비인두암 환자에서 용적세기조절회전 치료계획 시 삼차원입체조형치료계획 보다 유의하게 이하선에 평균선량이 줄었고 계획용 표적체적에 대한 conformity도 유의하게 향상되는 결과를 보였다. 본 연구가 적은 수의 환자를 대상으로 하였으나 용적세기조절회전치료기법을 시행 시 구강건조증의 발생을 줄일 수 있을 것으로 기대된다. 향후 더 많은 환자군을 대상으로 한 임상연구가 필요할 것으로 사료된다.

Age-related Changes of the Finger Photoplethysmogram in Frequency Domain Analysis (연령증가에 따른 지첨용적맥파의 주파수 영역에서의 변화)

  • Nam, Tong-Hyun;Park, Young-Bae;Park, Young-Jae;Shin, Sang-Hoon
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.12 no.1
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    • pp.42-62
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    • 2008
  • Objectives: It is well known that some parameters of the photoplethysmogram (PPG) acquired by time domain contour analysis can be used as markers of vascular aging. But the previous studies that have been performed for frequency domain analysis of the PPG to date have provided only restrictive and fragmentary information. The aim of the present investigation was to determine whether the harmonics extracted from the PPG using a fast Fourier transformation could be used as an index of vascular aging. Methods: The PPG was measured in 600 recruited subjects for 30 second durations, To grasp the gross age-related change of the PPG waveform, we grouped subjects according to gender and age and averaged the PPG signal of one pulse cycle. To calculate the conventional indices of vascular aging, we selected the 5-6 cycles of pulse that the baseline was relatively stable and then acquired the coordinates of the inflection points. For the frequency domain analysis we performed a power spectral analysis on the PPG signals for 30 seconds using a fast Fourier transformation and dissociated the harmonic components from the PPG signals. Results: A final number of 390 subjects (174 males and 216 females) were included in the statistical analysis. The normalized power of the harmonics decreased with age and on a logarithmic scale reduction of the normalized power in the third (r=-0.492, P<0.0001), fourth (r=-0.621, P<0.0001) and fifth harmonic (r=-0.487, P<0.0001) was prominent. From a multiple linear regression analysis, Stiffness index, reflection index and corrected up-stroke time influenced the normalized power of the harmonics on a logarithmic scale. Conclusions: The normalized harmonic power decreased with age in healthy subjects and may be less error prone due to the essential attributes of frequency domain analysis. Therefore, we expect that the normalized harmonic power density can be useful as a vascular aging marker.

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Analysis of Temperature Profiles by Land Use and Green Structure on Built-up Area (시가화지역 토지이용 및 녹지구조에 따른 온도변화 연구)

  • Hong Suk-Rwan;Lee Kyong-Jae;Han Bong-Ho
    • Korean Journal of Environment and Ecology
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    • v.19 no.4
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    • pp.375-384
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    • 2005
  • This study was conducted selecting 44 places with a block unit subject to urban area in Gangnam-gu, to analyze a temperature change according to land use and green structure. In this study, it was used the broad-wide urban temperature, supported by Landset TM and ETM+ satellite image 6scene(1999${\~}$2002). The result of the research, the land use pattern has slightly influence on a temperature change of urban area. The result from correlation analysis between temperature and the factors affected by land cover type, such as building-to-land ratio(A correlation coefficient is 0.368${\~}$0.709) have positive correlation and green area ratio(a correlation coefficient is -0.551${\~}$-0.860) have negative correlation. The result from correlation analysis between temperature and green capacity of the land, crown projection area ratio, each factor have negative correlation with temperature, as showing that a correlation coefficient of green capacity of the land is -0.577(June 2006)${\~}$-0.882(June 1999) and crown projection area ratio's is -0.549(June 2001)${\~}$-0.817(June 1999). The result of the regression analysis for establishing urban area temperature change prediction model showed that green capacity of the land of the explanation variable was accepted.

A Study on Business Value for the Creation of a Private Park regarding Long-term Non-executed Urban Parks - Focused on Long-term Non-executed Neighborhood Park in Gwangju Metropolitan City - (장기미집행 도시공원의 민간공원 조성을 위한 사업성 연구 - 광주광역시 장기미집행 근린공원을 중심으로 -)

  • Kim, Ho-Gyeom;Kim, Dong-Chan
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.5
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    • pp.81-91
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    • 2016
  • The study shows solutions of long-term unexecuted urban park and activation plans to facilitate the business promotion of Private Park Developers. This study conducted a feasibility analysis to determine if the business of a special case is applicable. The result of this study is as follows about three long-term unexecuted urban parks in Gwangju Metropolitan City's City Park. First, the three long-term unexecuted urban parks in Gwangju Metropolitan City's City Park are the forest type Neighborhood Parks. Businesses of a special case's park developing cost(average 0.4%) have a relatively low percentage. It is most affected by Land Compensation(average 33.8%) and building construction expenses(average 59.1%). Second, long-term unexecuted urban parks' Land Compensation and building construction expenses seed capital are excessive. The Bongsan Park balance floor space index is 179 percent; a reasonable profit floor space index is 220 percent. The Mareuk Park balance floor space index is 351 percent; a reasonable profit floor space index is 420 percent. The Jungoe Park balance floor space index is 327 percent; a reasonable profit floor space index is 400 percent. Third, to facilitate the business of special cases in deliberating, Bongsan Park should change its second class general residential area. Jungoe Park must change the quasi-residential area and semi-residential area. Mareuk Park must change the general commercial area. In this way, the feasibility of promoting private park projects will be improved.

The Effect of Obesity Levels on Irradiated Small Bowel volume in Belly Board with Small Bowel Displacement Device for Rectal Cancer Radiotherapy (복부판과 소장변위도구를 사용하는 직장암의 방사선치료 시 비만도가 소장의 조사용적에 미치는 영향)

  • Kim, Se-Young;Kim, Joo-Ho;Park, Hyo-Kuk;Cho, Jeong-Hee
    • Journal of radiological science and technology
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    • v.36 no.1
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    • pp.39-47
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    • 2013
  • For radiotherapy in rectal cancer patients treated with small bowel displacement device (SBDD) and belly board, We will suggest new indication of using SBDD depending on obesity index by analyzing correlation between obesity and irradiated small bowel volume. In this study, We reviewed 29 rectal cancer patients who received pelvic radiation therapy with belly board and SBDD from January to April in 2012. We only analyzed those patients treated with three-field technique (PA and both LAT) on 45 Gy (1.8 Gy/fx). We measured patients' height, weight, body mass index (BMI), waist-hip ratio (WHR) and divided BMI into two groups.(${\geq}23$:BMI=group1, <23:BMI=group2) We performed a statistical analysis to evaluate correlation between total volume of bladder($TV_{bladder}$), obesity index and high dose volume of small bowel (small bowel volume irradiated at 90% of prescribed dose, $HDV_{sb}$), low dose volume of small bowel (small bowel volume irradiated at 33% of prescribed dose, $LDV_{sb}$). The result shows, gender, WHR and status of pre operative or post operative do not greatly affect $HDV_{sb}$ and $LDV_{sb}$. Statistical result shows, there are significant correlation between $HDV_{sb}$ and BMI (p<0.04), $HDV_{sb}$ and $TV_{bladder}$ (p<0.01), $LDV_{sb}$ and $TV_{bladder}$ (p<0.01). BMI seems to correlate with $HDV_{sb}$ but does not with $LDV_{sb}$ (p>0.05). There are negative correlation between $HDV_{sb}$ and BMI, $TV_{bladder}$ and $HDV_{sb}$, $TV_{bladder}$ and $LDV_{sb}$. Especially, BMI group1 has more effective and negative correlation with $HDV_{sb}$ (p=0.027) than in BMI group2. In the case of BMI group 1, $TV_{bladder}$ has significant negative correlation with $HDV_{sb}$ and $LDV_{sb}$ (p<0.04). In conclusions, we confirmed that Using SBDD with belly board in BMI group1 could more effectively reduce irradiated small bowel volume in radiation therapy for rectal cancer. Therefore, We suggest using belly board with SBDD in order to reduce the small bowel toxicity in rectal radiotherapy, if patients' BMI is above 23.