• Proceedings of the Korean Society of Community Living Science Conference
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• 2009.09a
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• pp.83-83
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• 2009

암을 제외한 대부분의 성인병은 혈액순환과 관련된 혈관계 질환들로 이들에 의한 사망 비율의 합은 암의 비율과 비슷하게 나타나 혈관계 질환의 심각성을 나타내고 있다. 혈전에 의한 혈관계 질환은 혈전용해제와 트롬빈저해제를 이용하여 치료하고 예방할 수 있으며, a-glucosidase 저해제는 당뇨병 예방과 치료에 이용할 수 있다. 예로부터 민간요법에서 다양하게 이용되어 왔던 반하를 성인병 치료와 예방에 관련된 기능성식품의 자료로 사용하기 위해 반하 열수추출물을 유기 용매로 분획화하고 분획물의 혈전용해활성, 트롬빈저해활성, 혈당강하효과를 측정하였다. 혈전을 직접 용해하는 활성을 측정하기위해 100 mg/ml의 농도로 준비한 시료액을 fibrin plate 방법을 이용하여 혈전용해활성을 측정 결과 hexane 층, chloroform 층, ethyl acetate 층, butanol 층에서는 활성을 나타내지 않았지만 물 층에서 만 0.8 plasmin unit의 높은 혈전용해활성을 나타냈다. 혈전의 형성을 억제하기위해 혈전형성의 필수 효소인 트롬빈의 활성을 저해하는 트롬빈저해활성을 측정하기위해 10 배 희석한 (10 mg/ml) 시료 용액을 이용하여 트롬빈저해활성을 측정결과 hexane 층에서 75.3%의 높은 트롬빈저해활성을 나타냈으며, ethyl acetate 층과 chloroform에서도 각각 43.3%와 39.7%의 활성을 나타냈다. 또한 탄수화물의 소화를 지연시킴으로서 소장에서 포도당의 흡수를 억제하여 혈관내 당의 농도를 조절하는 혈당강하제의 개발을 위해 준비된 조효소액(10 mg/ml)을 이용하여 a-glucosidase 저해활성을 측정한 결과 ethyl acetate 층과 hexane 층에서 각각 24.9%와 23.4%의 저해활성을 확인하였다. 따라서 반하의 hexane 층과 ethyl acetate 층과 물층은 혈전관련 혈관계 질환과 당뇨병 관련 기능성 식품의 개발 소재로 이용할 수 있을 것으로 기대된다. 특히 최근 질병 치료에 효과는 크지만 부작용이 동반되는 화학약품들 대신 활성은 조금 뒤지지만 부작용이 없는 생약을 이용하려는 경향이 커지고 있다. 따라서 오랫동안 민간용법에서 사용되고 있는 반하는 안정성이 확인된 장점을 갖고 있어, 식품재료나 기능성 음료에 이용할 경우 장기간 섭취가 가능해 혈관계 질환의 치료와 예방에 큰 효과를 가져 올 수 있을 것으로 기대된다.

• Journal of the Korea Society of Computer and Information
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• v.17 no.10
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• pp.11-23
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• 2012

To achieve efficient code size reduction, this paper proposes a new compressed instruction set architecture for the OpenRISC architecture. The new instructions and their corresponding formats are designed by the profiling information of the existing instruction usage. New 16-bit instructions and 32-bit instructions are proposed to compressed the existing 32-bit instructions and instruction sequences, respectively. The proposed instructions can be classified into three types. The first is the new 16-bit instructions for the frequent normal 32-bit instructions such as add, load, store, branch, and jump instructions. The second type is the new 32-bit instructions for the consecutive two load instructions, two store instructions, and 32-bit data mov instructions. Finally, two new 32-bit instructions are proposed to compress function prolog and epilog code, respectively. OpenRISC hardware decoder is extended to support the new instructions. Experiments show that the efficiency of code size reduction improves by an average of 30.4% when compared to the OR1200 instruction set architecture without loss of execution performance.

• Korean journal of applied entomology
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• v.10 no.1
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• pp.13-22
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• 1971

This experiment was conducted to investigate the differences of the in vitro inhibitory effect of various organephobphorua insecticides on the chlinesterase from rice stem borer and those of the toxicity of them against the insect, with special references to the relationship between the cholinesterase inhibition and the toxicity. The results obtained were summarized as follows: Phosphate compounds shelved stronger inhibitory effect on the cholinesterase than thhiophosphate compounds, but was not stronger in toxicity than the latter. Diethoxy compounds were not always stronger than dimethoxy in cholinesterase inhibition and the toxicity of organophosphorus insecticides. The organophosphorus insecticides that inhibited strongly the cholinesterase were not always stronger in the toxicity.

• Proceedings of the Korean Society for Language and Information Conference
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• 2001.06a
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• pp.199-225
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• 2001

The main goal of this paper is to investigate and compare English, German and Korean non-head-bound-intensifiers such as English ‘x-self’, German ‘selbst’, and Korean ‘susulo, casin’. That is, this paper is mainly concerned with the semantic domain where the respective contributions of the expressions in question overlap. The phenomenon under discussion with the label “intensifiers” is regarded as universal, which provides the ground of the comparative/contrastive or semi-cross-linguistic study of this paper. Not only the semantic concept of intensification by these expressions but also the combination of grammatical features or syntactic behaviours thereof seem to have highly invariant common denominators among the wide varieties of languages, even if they come from apparently different language families. In comparing English, German and Korean intensifiers, this paper is interested in the more general features of the expressions in question rather than some language-specific idiocyncracies. Intensifiers work similarly not only in English and German, but also in Korean. Each of three languages under investigation provides some sort of a safegard against confusing instances and misleading judgements on the issues under discussion. Morphologically, however, English expressions in question agree with their rele-vant NP in number, gender and person. Whereas German and Korean counterparts do not have such specific morphological properties. Intensifiers in their non-head-bound-use are subject-oriented, just as in their head-bound use. Non-head-bound-intensifiers differ from head-bound-intensifiers mostly in their syntactic behaviours or distributional properties, whereas they share the semantic domain “intensification” regarding relevant subject-NP. They introduce an ordering and distinguish center and periphery, and ‘self-involvement (directness of involvement)’seems a additional possible characterisation of the relevant dimension of these intensifiers in common. An assertion of identity also can be reg

• Korean Institute of Interior Design Journal
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• v.13 no.5
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• pp.106-113
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• 2004

The purpose of this study is to present the dwelling space by attaching or inserting the mobile space unit to the fixed building by providing the temporary dwelling space for those suffering from flood disaster, natural disaster or solitary old people or the space and program that the completed building in the city can not provide such as temporary events in the bridge, passage space, walking space for the handicapped, stores located between street blocks, and plaza. Therefore, this study was intended to investigate temporary dwelling space through the composition of space and the experiment of the applicability of the program through the methods of movement, folding, module, expansion and evolution of mobile space. An attempt was made to apply the concept of ‘mobile space’ to the dwelling space not only with a focus on the freedom of variable and changeable physical movement but also with a focus on the existence of the nomad and the way of thinking that bleaks away from a given value system and code, creates a new value and continues to move to a new domain. This study attempted to analyze how the concept of ‘mobile space’ has been developed in what form and method they have been applied and interpreted in the historical background. It attempted to resolve the concepts of movement and mobility through the experiment so that they might apply to the space of contemporary city. This study attempted to experiment this possibility using the mobile space unit and apply it.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.130-130
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• 1993

실험목적: KR 53170 및 KR 53234 는 천연물에서 분리 추출한 화합물로 terpene lacton ring을 가진 약산성 물질이다. in vitro 항종양 실험에서 종양억제효과가 있었고 in vivo 항종양 실험에서도 유의성 있는 효과가 있었으며 급성 경구독성시험에서도 독성이 낮은 것으로 평가 되었다. 이에 따라 KR 53170 등의 약물동태학적인 성질을 연구하여 독성실험과 임상실험을 위한 용법용량을 결정하고 나아가 본약물의 제제개발에 도움이 되도록 본 연구를 시행하였다. 방법: KR 53170 및 53234은 경구시 20mg/kg, 정맥투여시는 10mg/kg로 투여하였다. Rat의 혈장 sample 채취는 ether로 흡입마취 시킨 후 heart puncture 하였다. 뇨시료는 대사 cage를 이용하여 채취하였으며 얻어진 모든 시료는 HPLC로 분석 하였다. 분석결과는 computer program 'Multi-free'를 이용하여 주요 pqarameter를 산출하였다. 인체혈액에 대한 혈청단백결합율 측정은 ultrafiltration법을 이용하였다. 즉 YMT membrane을 이용하여주요 parameter를 산출하였다. 인체혈액에 대한 혈청단백결합율 측정은 ultrafiltration법을 이용하였다. 즉 YMT membrane을 이용하여 유리약물을 분리하여 HPLC로 정량하였다. 결과 및 고찰: 1. KR 53170 10mg/kg 정맥투여시 최고혈중농도는 0.55ug/ml, 반감기는 0.51hr, 분포용적은 4.5L이었다. 20mg/kg를 경구 투여시 최고 혈중농도는 0.18ug/ml, 반감기는 3.5기산이고 AUC는 0.91ug.ml, 분포용적 28Lm, Ka 3.49$hr^{－1}$ 그리고 Cl는 5.5L/hr/kg이었다. 이는 투여용량에 비해 매우 적은량이 흡수되고 배설 된 것으로 약물이 혈액에 대한 용해도 문제에 기인하는 것으로 간주된다. 2. KR 53234 10mg/kg 정맥투여후의 최고혈중농도는 1.14ug/ml, 반감기는 0.50hr, 분포용적은 2.2L이었다. 20mg/kg 경구 투여시의 최소 혈중 농도는 0.33 ug/ml, 소실반감기는 1.5시간, AUC는 0.942ug.hr/ml, 분포용적 11L, Ka는 3.05 $hr^{－1}$ 그리고 Cl는 5.3L/hr/kg이었다. 이는 KR 53170에서와 같이 매우 적은량이 흡수되고 배설되었다. 3. KR 53170의 혈청단백 결합율은 5-500 ug/ml 범위에서 78.7-86.2%이었고 KR 53234의 혈청단백결합율은 5-100 ug/ml 범위에서 79.6-71.2%이었다.이었다.

• Environmental and Resource Economics Review
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• v.23 no.2
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• pp.331-347
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• 2014

The purpose of this study is to estimate the economic value of the recreational sea fishing in the Yellow Sea using count data model. For estimating consumer surplus, we used several count data model of travel cost recreation demand such as a poisson model(PM), a negative binomial model(NBM), a truncated poisson model(TPM), and a truncated negative binomial model(TNBM). Model results show that there is no exist the over-dispersion problem and a NBM was statistically more suitable than the other models. All parameters estimated are statistically significant and theoretically valid. The NBM was applied to estimate the travel demand and consumer surplus. The consumer surplus pre trip was estimated to be 254,453won, total consumer surplus per person and per year 1,536,896won.

• Journal of the Korean Society for Library and Information Science
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• v.29
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• pp.205-230
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• 1995

The publication of books on modern agriculture started under the influence of Silhak Thought developed from the late Chosun Dynasty. The common intention found in these publications is the objective to enrich the country through increased agricultural productivity and thus to secure national independence from the surrounding powers. The study reviews three different categories in this area; five general books on agriculture, three on agriculture related legal regulations, and ten books introducing techniques of commercial agriculture. The first category is comprehensive treatment of general agricultural content and the second is legal regulations which affected the contemporary agriculture. The third category is introductory books on commercial techniques aimed at accumulating wealth through agriculture. Silkworm cultivation occupies an important place in these publications owing to the active encouragement given by the Section of Silkworm Cultivation in the Ministry of Agriculture, Commerce and Industry. We can recognise the extensive involvement of Suh Pyung Sook, who served as the Section Chief of Silkworm Cultivation in 1904, by examining introductions and prefaces of many books in this category. The examples of general books on agriculture are 'New Agricultural Administration' (농정신편), 'General Introduction on Agiculture' (농업대요), 'New Textbook on Agricuture' (신찬농업교과서), 'Pragmatic Agriculture' (실리농방신편), Of these, 'New Agricultural Administration' (농정신편) is evaluated as the first publication on modern agriculture. It was written in 1881, and the first edition was published was published in 1901 with the second edition following in 1905. Examples of the second category are; 'The regulation on utilizing uncultivated state owned land' (국유미간지리용법) legislated and declared with the intention of expanding cultivated area, 'Mining and Forestry Regulation' (광임법규), 'Forest Land Regulation' (임야법령) to administer mining and forestry. Books on commercial agriculture take up the highest proportion in the agricultural publication of this period. These cover silkworm cultivation, chicken farming, vegetables and fruits. The books introduce Western techniques with more scientific and rational approach especially on Silkworm cultivation and chichen farming which had become increasingly significant as commercial agriculture from the late Chosun Dynasty.

• Proceedings of the Korea Society for Energy Engineering kosee Conference
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• 1995.05a
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• pp.45-52
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• 1995

The photocatalytic activity of TiO$_2$ was investigated as a function of added amount of Nb$_2$O$_{5}$, heat treatment temperature and the decomposition rate of 1 mM dichloroacetic acid(DCA). Mixed oxides of TiO$_2$ and Nb$_2$O$_{5}$ was prepared by the sol-gel process. The addition of Nb$_2$O$_{5}$ into TiO$_2$ has deleterious effect on the decomposition rate of DCA, which was decreased as the amount of Nb$_2$O$_{5}$ was increased. The excess electrons due to the doping of Nb$_2$O$_{5}$ into TiO$_2$ can promote the reduction process instead of oxidation or recombination rate with electron holes. The most efficient photocatalyst was the one heat treated at 40$0^{\circ}C$ for an hour as far as the heat treatment temperature is concerned. The lower the pH of the solution, the higher the quantum yield.tum yield.

• Informatization Policy
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• v.19 no.4
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• pp.83-104
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• 2012

Information sharing is one of the key factors enhancing government efficiency and public convenience. However, critics argue that Korean government is now facing various kinds of barriers such as insufficient collaboration among agencies, inappropriate statutes, and technical problems. Thus, this study aims to develop policy alternatives that help resolve the existing problems suggested above. In order to achieve research objectives, this study employs both quantitative and qualitative methods as ways to investigate different dimensions of information sharing in government. Both survey and interview include six dimensions such as organization, technology, culture, management, policy and law. The results show that Korean government needs to implement following alternatives; developing its own database that helps support government decision making, changing organizational culture, continuous extension in terms of the number of object information and affiliated agency, and developing a statute dealing with government information sharing.