• Title/Summary/Keyword: 요인실험계획

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Effects of Dietary Factors on Lymphocyte DNA Damage in Smoking Elderly People in Korea (식이 요인이 SCE 빈도수로 본 흡연노인 임파구 DNA손상에 미치는 영향)

  • 강명희;이정희
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.3
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    • pp.523-532
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    • 2004
  • The spontaneous frequency of genetic damage and the possible relationship of this damage to dietary and nutritional variables were investigated in peripheral blood lymphocytes from 45 elderly people using sister chromatid exchange (SCE). The relationship of dietary and nutritional factors on SCE was assessed by different degrees of smoking status such as smokers (n=14), ex-smokers (n=16) and non-smokers (n=15). Significant relationship of the SCE frequency to nutrient intake of the combined subjects (n=45) was found. When cigarette smoking status was taken into account, there were negative linear relationships between SCE and fat, phosphorus or vitamin A intakes of the non-smokers as well as SCE and the dietary quality scores. There was a positive linear relationship between SCE and food frequency of meat and fish among the smokers. Use of artificial sweetners in ex-smokers of the elderly people produced a significant increase of SCE in comparison with the mean SCE for those not using sweetners. Other dietary parameters, including intake of coffee, green tea and ginseng tea, alcohol consumption, use of processed foods, and administration of vitamin pills did not show any correlation with SCE. These results suggested that dietary fat, phosphorus or vitamin A status are the major determinants of spontaneous DNA damage in lymphocytes of the elderly people.

Design and Application of Career Education Program Related to the Subject Manual Training and Home Economics of Middle School (중학교 기술·가정교과와 연계한 진로교육 프로그램의 구안과 적용)

  • Lee, Hee Soon;Kim, Hee Jin;Yun, Song Hea;Cheon, Seong Moon
    • Journal of vocational education research
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    • v.29 no.3
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    • pp.247-263
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    • 2010
  • The purpose of this study is making the career education program related to the subject, Manual Training and Home Economics, to present the effective guidance and to improve career maturity of students about the unit, "Making a choice of career and Job ethics" of middle school senior's course. In order to estimate this program, 60 students of 2 classes were chosen as research subjects among middle school seniors and each of classes was divided into two groups, an experimental group and a control group. After the experimental group was trained the career education program related to Manual Training and Home Economics for 15 sessions, the effect was verified by comparing tests before and after program execution. In order to prove effects of the program. Each grade of both the experimental group and the control group was taken analysis of covariance (ANCOVA). Result of the program experiment is following. First, after executing the career education program related to Manual Training and Home Economics to the experimental group, participants showed that both attitude and ability for career maturity were improved in each sub-factor field of the career maturity as a result of tests before and after program execution. Second, in program satisfaction estimation, most of students had a positive attitude and in every time satisfaction, they made high estimation on the program, especially including the proper level of students and interesting activities. Finally, the final program was completed based on the result of effect analysis of the program.

Reliability and Accuracy of Digital Impression Obtained from CS-3500 Intraoral Scanner (CS-3500 구강 내 스캐너로 채득된 디지털 인상의 신뢰도 및 정확도 평가)

  • Kim, Sa-Hak;Kim, Jae-Hong;Kim, Chong-Kyen
    • Journal of dental hygiene science
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    • v.15 no.5
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    • pp.673-678
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    • 2015
  • The purpose of this study was to evaluate the reliability and accuracy of linear measurements in digital models compared to master model. A master model (ANKA-4; Frasaco GmbH, Tettnang, Germany) with the prepared upper full arch tooth was used. Four linear measurements were recorded between landmarks, directly on the master model and the digital models by a single examiner. Measurements were made with a digital caliper from manual model and with the software from the virtual models. The t-test for paired samples and intraclass correlation coefficient (ICC) were used for statistical analysis. The measurement of two methods showed good reliability. The mean differences between master and digital model were 0.06~0.12 mm. These in vitro studies show that accuracy and reliability of the digital impression is similar to that of the gold standard. Therefore digital impression was also considered to be a acceptable for placement clinically.

Comparative study on experimental measurements of discharge using various flow meters (유속측정 기기별 측정성과에 대한 실험적 비교분석)

  • Lee, Jae-Hyug;Kang, Kyang-Min;Jung, Sung-Won;Kim, Tae-Woong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2009.05a
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    • pp.1908-1912
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    • 2009
  • 유량자료는 물의 순환과정을 규명하고 효율적인 수자원 개발 및 이수 치수 계획 등에 매우 귀중하게 이용된다. 그러나 이러한 유량자료를 확보하는 데는 많은 시간과 경비 등이 요구되기 때문에 주요 수위의 유량측정자료로 수위-유량관계 곡선식(Stage-Discharge Curve)을 개발하여 유량자료를 환산하고 있다. 따라서 수위-유량관계 곡선식의 신뢰도는 유량자료의 품질에 절대적인 영향을 미치는 요인으로 작용된다. 수문학을 연구하는 많은 학자들은 고품질의 유량자료를 생산하여 신뢰성 있는 곡선식을 개발하고자 유량측정 방법과 기준, 장비개량 등에 관한 연구를 수행하고 있다. 측정하고자 하는 기기별 측정 성과에 대한 연구 자료가 거의 없이 국내에 보급된 다양한 유속측정기기를 사용하여 유량자료를 생산하여 활용하고 있다. 본 연구에서는 규격화된 콘크리트 수로에 일정한 유량을 흘려보내고 다양한 측정기기를 이용하여 유속을 측정하였다. 그리고 이 측정성과를 이용하여 유량을 산정하고 비교분석하였다. 실험을 위해서 국내에서 일반적으로 사용되고 있는 측정기기로 마그네틱유속계(Electromagnetic Current Meter), 휴대용유량계(Flow Meter), 프라이스유속계(USGS Type AA Current Meter), 갈수기용유속계(USGS Pygmy Meter)등의 장비를 사용하였으며, 동일한 조건에서 유량을 얻음으로 측정 기기가 제시하는 유량을 알 수 있었다. 비교검토에 적용하고자 측정한 수심으로는 0.25m, 0.30m, 0.35m, 0.40m의 4개 Case로 진행이 되었으며, 측정방법으로는 도섭법(Wading Measurement)에 의하거나 케이블웨이(Cableway), 교량법(Bridge Measurement), 보트법(Boat Measurement)등이 있으나, 신뢰성과 정확도를 높이기 위해 도섭법으로 수면에서 0.6d 지점의 유량측정방법(1점법)을 적용하였다. USGS Type AA Current Meter, USGS Pygmy Meter는 유속측정기기의 검교정을 받았으므로 다른 실험유속측정치의 비교를 위한 기준값으로 사용하였다. 따라서 국내에서 널리 사용되는 측정기기(Electromagnetic Current meter, Flow Meter, USGS Type AA Current Meter, USGS Pygmy Meter)별 검토 결과 프라이스유속계를 기준으로 마그네틱유속계는 ${\pm}$10% 이상, 갈수기용 유속계 및 휴대용 유량계는 ${\pm}$5% 미만의 차이가 있음을 확인할 수 있었다.

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Optimization of Crude Papain Extraction from Papaya Latex Using Response Surface Methodology (반응표면 분석법에 의한 crude papain 추출 조건의 최적화)

  • Oh, Hoon-Il;Oh, Sang-Joon;Kim, Jeong-Mee
    • Korean Journal of Food Science and Technology
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    • v.29 no.3
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    • pp.509-515
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    • 1997
  • Crude papain was extracted from papaya latex under various conditions. Extraction conditions of crude papain were optimized by the response surface methodology (RSM). Extraction yield of papain was affected by concentration of $NaHSO_3$, extraction time and pH. Three independent factors were chosen to determine their effects on the various responses and the function was expressed in terms of a quadratic polynomial equation, which measures the linear, quadratic and interaction effects. According to the results of RSM, the stationary point for quantitatively dependent variable was found to be the maximum point for extraction yield. Optimum conditions of papain extraction were 4% of $NaHSO_3$, 120 min of extraction time and pH 7.6. Under these conditions, 793.16 mg of papain per g latex was extracted from papaya latex.

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Design of Cold Forging Process of Micro Screw for Mobile Devices (모바일 기기용 초소형 나사의 냉간 단조 공정 설계)

  • Choi, Du-Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.3692-3697
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    • 2015
  • A screw is a type of fastener characterized by a helical ridge known as thread. The demands for screws with the miniaturization and weight reduction are increasing for the trend of small size of mobile devices. The successful designs of mold and process are very important to obtain screws with good mechanical properties and high precision. In this study, the design of cold forging process of micro screw was carried out by using finite element method. In particular, in order to investigate the effects of die geometries and friction, design of experiment method was adopted and it was revealed that the friction was the dominant factor of folding defects. From these results, the design of die was modified and experiments were carried out with the modified die. From the experimental results, it was found that the folding defects disappeared.

Decomposition Characteristics of Fungicides(Benomyl) using a Design of Experiment(DOE) in an E-beam Process and Acute Toxicity Assessment (전자빔 공정에서 실험계획법을 이용한 살균제 Benomyl의 제거특성 및 독성평가)

  • Yu, Seung-Ho;Cho, Il-Hyoung;Chang, Soon-Woong;Lee, Si-Jin;Chun, Suk-Young;Kim, Han-Lae
    • Journal of Korean Society of Environmental Engineers
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    • v.30 no.9
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    • pp.955-960
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    • 2008
  • We investigated and estimated at the characteristics of decomposition and mineralization of benomyl using a design of experiment(DOE) based on the general factorial design in an E-beam process, and also the main factors(variables) with benomyl concentration(X$_1$) and E-beam irradiation(X$_2$) which consisted of 5 levels in each factor was set up to estimate the prediction model and the optimization conditions. At frist, the benomyl in all treatment combinations except 17 and 18 trials was almost degraded and the difference in the decomposition of benomyl in the 3 blocks was not significant(p > 0.05, one-way ANOVA). However, the % of benomyl mineralization was 46%(block 1), 36.7%(block 2) and 22%(block 3) and showed the significant difference of the % that between each block(p < 0.05). The linear regression equations of benomyl mineralization in each block were also estimated as followed; block 1(Y$_1$ = 0.024X$_1$ + 34.1(R$^2$ = 0.929)), block 2(Y$_2$ = 0.026X$_2$ + 23.1(R$^2$ = 0.976)) and block 3(Y$_3$ = 0.034X$_3$ + 6.2(R$^2$ = 0.98)). The normality of benomyl mineralization obtained from Anderson-Darling test in all treatment conditions was satisfied(p > 0.05). The results of prediction model and optimization point using the canonical analysis in order to obtain the optimal operation conditions were Y = 39.96 - 9.36X$_1$ + 0.03X$_2$ - 10.67X$_1{^2}$ - 0.001X$_2{^2}$ + 0.011X$_1$X$_2$(R$^2$ = 96.3%, Adjusted R$^2$ = 94.8%) and 57.3% at 0.55 mg/L and 950 Gy, respectively. A Microtox test using V. fischeri showed that the toxicity, expressed as the inhibition(%), was reduced almost completely after an E-beam irradiation, whereas the inhibition(%) for 0.5 mg/L, 1 mg/L and 1.5 mg/L was 10.25%, 20.14% and 26.2% in the initial reactions in the absence of an E-beam illumination.

Effect of Various Regression Functions on Structural Optimizations Using the Central Composite Method (중심합성법에 의한 구조최적화에서 회귀함수변화의 영향)

  • Park, Jung-Sun;Jeon, Yong-Sung;Im, Jong-Bin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.1
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    • pp.26-32
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    • 2005
  • In this paper, the effect of various regression models is investigated on structural optimization using the central composite method. Three bar truss and the upper platform of a satellite are optimized using various regression models that are polynomial, exponential and log functions. Response surface method is non-gradient, semi-global, discrete and fast converging in optimization problem. Sampling points are extracted by the design of experiments using the central composite method. Response surface is generated using the various regression functions. Structural analysis for calculating constraints is executed to find static and dynamic responses. From this study, it is verified that the response surface method has advantage in optimum value and computation time in comparison to other optimization methods.

Sample Average Approximation Method for Task Assignment with Uncertainty (불확실성을 갖는 작업 할당 문제를 위한 표본 평균 근사법)

  • Gwang, Kim
    • Journal of Korea Society of Industrial Information Systems
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    • v.28 no.1
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    • pp.27-34
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    • 2023
  • The optimal assignment problem between agents and tasks is known as one of the representative problems of combinatorial optimization and an NP-hard problem. This paper covers multi agent-multi task assignment problems with uncertain completion probability. The completion probabilities are generally uncertain due to endogenous (agent or task) or exogenous factors in the system. Assignment decisions without considering uncertainty can be ineffective in a real situation that has volatility. To consider uncertain completion probability mathematically, a mathematical formulation with stochastic programming is illustrated. We also present an algorithm by using the sample average approximation method to solve the problem efficiently. The algorithm can obtain an assignment decision and the upper and lower bounds of the assignment problem. Through numerical experiments, we present the optimality gap and the variance of the gap to confirm the performances of the results. This shows the excellence and robustness of the assignment decisions obtained by the algorithm in the problem with uncertainty.

Effects of Action Learning Approach on Learning Motivation and Problem-solving Capacity in NCS Vocational Competency Class of Polytechnic College (폴리텍대학 NCS 직업기초능력 수업에서 액션러닝방식이 학습자의 학습동기와 문제해결력에 미치는 영향)

  • Kim, Yeon-Chul;Lee, Eun-Chul
    • The Journal of the Korea Contents Association
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    • v.16 no.11
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    • pp.38-52
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    • 2016
  • This study analyzed effects of Action Learning approach on enhancing learning motivation and improving problem-solving capacity in NCS vocational competency classes of Polytechnic College. Targeted group is B Polytechnic College located in Chungnam, and 53 students in experimental group and 64 students in control group. analysis of data is descriptive statistic analysis and the multivariate analysis of variance (MANOVA) method to study sub factors of learning motivation and problem-solving ability. As a result, Action Learning approach has a great influence on connection, confidence, and satisfaction, among the sub factors of learning motivation. also figured that the approach has positive effects on problem clarifying, cause analysis, alternative developing, planning/practicing, and performance assessment, among the sub factors of problem-solving capacity. Moreover, Polytechnic College's NCS vocational competency classes are desirably required to adopt the approach of Action Learning for their educational method, as it fosters basic competencies, such as understanding of diverse perspectives, communicating, leadership, interpersonal relationship, self-development, coping with conflicts, operating meetings, to be learned while students are doing problem-solving activities under a team-working atmosphere.