• The Korean Journal of Zoology
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• v.10 no.2
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• pp.15-17
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• 1967

1. 송충(Dendrolimus spectabilis)의 요산을 성장과 변태에 따라 측정하였다. 2. 초기유충체의 뇨산농도는 비교적 낮으나 전용기에서 증가, 3 일된 용에서 최고도에 달하고 후기용에서는 감소, 후기의 성충에서 최소치를 보이고 있다.3. 일반적으로 male 은 female 보다 높은 농도의 요산을 가지고 있다. 4. Haemolymph 에 있어서 요산농도의 변화는 불규칙적이나, feces 에 있어서는 상승하는 경향을 보이고 있다.

• The Journal of the Korea Contents Association
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• v.17 no.2
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• pp.38-46
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• 2017

This research aimed to identify the correlation between the metabolic syndrome, which is one of the cardiovascular risk factors and emerging as an issue in the society, and the serum uric acid level. The research was conducted on a total of 1,444 patients who took a medical examination at a health examination center. The research subjects were composed of 977 men and 467 women. By conducting physical measurement and the blood test on the subjects, the research identified the correlation between the serum uric acid level and the metabolic syndrome and compared the number of the risk factors by dividing the class of the serum uric acid. The average level of serum uric acid was identified higher in men at $6.30{\pm}1.39mg/dL$ than $4.43{\pm}0.89mg/dL$ in women. Men had a correlation between age, waist size, systolic blood pressure, neutral fat, HDL-cholesterol, WBC count and ESR and the serum uric acid level (p<0.05), while women had a correlation between waist size, diastolic blood pressure level, neutral fat, HDL-cholesterol and ESR and the serum uric acid level (p<0.05). The number of the risk factors depending on the serum uric acid level increased as the serum uric acid level rose. The overall prevalence rate of the metabolic syndrome was higher in men at 17.4% than 10.2% in women. This showed that there is a statistically relevant relevance between the metabolic syndrome and the serum uric acid level, and the number of the risk factors of the metabolic syndrome will go up with an increase in the serum uric acid level.

• Journal of the Korean Society of Radiology
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• v.84 no.1
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• pp.212-225
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• 2023

Purpose We retrospectively investigated the characteristics of patients with monosodium urate (MSU) deposits of the hand and wrist on dual-energy CT (DECT) compared to those without. We also attempted to determine the pattern of MSU distribution in DECT. Materials and Methods In total, 93 patients were included who had undergone DECT for evaluation of the hand or wrist pain under the clinical impression of gouty arthritis. The total volume of MSU deposits on DECT was calculated and the pattern of MSU distribution on DECT was analyzed. Also, the level of the serum urate at the time of DECT and the highest level of the serum urate of the patients were obtained from their records and the relationship between MSU and serum urate level was evaluated. Results The range of the volume of MSU deposits on DECT was 0.01-16.11 cm³ (average: 1.07 cm³). The average level of serum urate was significantly higher in the MSU positive group than that in the MSU negative group. MSU deposits were most frequently observed in the wrists followed by fingers and digitorum tendons. Conclusion On DECT, MSU deposits were most frequently detected in the wrist and related with high serum urate level.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.1
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• pp.42-49
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• 2019

This study compared the utility of the serum uric acid/creatinine ratio with that of uric acid as a risk predictor of metabolic syndrome. From November 2016 to October 2018, 14,190 adult men under the age of 20 years, who underwent a comprehensive health checkup at a general hospital in their metropolitan area, were included. Metabolic syndrome was assessed according to the American Heart Association/National Heart Lung and Blood Institute (AHA/NHLBI) criteria. Abdominal obesity was based on the WHO criteria in the Western Pacific region. The serum uric acid/creatinine ratio was found to be higher in the fourth quartile than in the first quartile, with a high incidence of metabolic syndrome and metabolic syndrome components. On the other hand, ROC analysis revealed the serum uric acid/creatinine ratio to be a similar indicator of the metabolic syndrome risk to serum uric acid (AUC, 0.554 vs 0.566). The serum uric acid/creatinine ratio showed lower sensitivity and higher specificity than uric acid. In conclusion, the utility of the serum uric acid/creatinine ratio as an independent indicator to predict the risk of metabolic syndrome is limited, and should be used only as an auxiliary marker.

• 건강소식
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• v.36 no.9
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• pp.28-29
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• 2012

관절염의 일종인 통풍은 말 그대로 바람만 불어도 아플 정도로 격심한 관절통이 오는 병이다. 주로 혈중 요산치가 높은 중년 이후의 남자에서 많이 발생했지만 최근 들어 20~30대 남성 환자들이 급증하고 있는 추세다. 젊은 연령층 발병이 문제가 되는 것은 통풍이 완치되는 질병이 아니기 때문이다.

• Journal of the Korean Electrochemical Society
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• v.3 no.4
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• pp.232-234
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• 2000

Determination of uric acid by electrochemical method using ultrasonic stimulation has been investigated. Effects of sonication power, sonication time, pH of the solution and temperature were studied to obtain the optimal analytical conditions. The stability of the electrode was also examined. The optimal conditions for the sonovoltammetric determination of uric acid were as follows: temperature, $25.0^{\circ}C$ pH 7.0; sonication power, $20W/cm^2$. The calibration curve for the determination of uric acid by sono-LSV was linear over the range of$8.0{\times}10^{-6}\~5.0\times10^{-4}M$ and the limit of detection was $6.5\times10^{-6}M$.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.342-352
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• 2021

We used data from the 7th Korea National Health and Nutrition Examination Survey (KNHANES) (2016~2018) to investigate an association between high sensitivity C-reactive protein (hsCRP) and uric acid in the obese. Obesity was defined as a body mass index (BMI) of 25 kg/m² or more, severe obesity as a BMI of 30 kg/m² or more, and morbid obesity as a BMI of 35 kg/m² or more. In the complex samples multiple logistic regression, despite adjustment by adding major risk factors, the odds ratio (OR) for obesity was higher in the group with high levels of both, hsCRP and uric acid than the reference group at all stages (obesity, OR 1.89, P<0.001 vs. severe obesity, OR 5.04, P<0.001 vs. morbid obesity, OR 8.20, P<0.001). The association between hsCRP and uric acid in obese patients increased from 1.89 to 8.20 as the obesity level increased, suggesting that participants with increased BMI were significantly affected by hsCRP and uric acid. Moreover, the interaction between hsCRP and uric acid was statistically significant even in the model corrected for major confounding factors (P for interaction=0.009).

• Korean Journal of Clinical Laboratory Science
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• v.51 no.1
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• pp.50-56
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• 2019

This study examined the relationship between the serum GGT (gamma-glutamyl transferase) and uric acid level in obese male adults. A total of 14,283 adult males aged 20 years or more, who visited the health examination center of Gyeonggi Regional General Hospital from January 2017 to August 2018 and underwent a physical examination, were enrolled in this study. The obesity criteria were defined by the Asia-Pacific regional standards. Abdominal obesity was defined as a male waist circumference of more than 90 cm. An increase in the serum uric acid and serum CGT levels of the male subjects was defined as 7.0 mg/dL or more and 56 IU/L or more, respectively. The results showed that the serum GGT and uric acid levels were higher in the overweight and obese groups than in the normal weight group. In the obese group, the serum GGT and uric acid were significantly higher in the patients with abdominal obesity. On the other hand, there was no difference compared to the low body weight group. The overweight and obesity groups showed a higher risk of elevated serum GGT and hyperuricemia than the normal weight group, but a low body weight did not affect the serum GGT elevation and hyperuricemia. Overall, the serum GGT and uric acid levels are useful for evaluating overweight and obesity in adult males.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.240-250
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• 2020

The purpose of this study was to investigate the relationship between serum uric acid levels, insulin resistance and components of metabolic syndrome. It was conducted on 4,428 adults over the age of 20 who had undergone health checkups at a general hospital in Gyeonggi-do from June 2018 to May 2020. As a result of the study, uric acid levels were higher in the metabolic syndrome subjects than normal subjects in both men and women. and the incidence of metabolic syndrome and its components was higher in the hyperuricemia group than in the normal group. Hyperuricemia was found to increase the risk of elevated blood pressure(p=0.006) and hypertriglyceridemia(p<0.001) in men and metabolic syndrome(p=0.012) and low HDL-cholesterol(p<0.001) in women. Thus, in both men and women, hyperuricemia was associated with metabolic syndrome and its components, and it was confirmed that it was an independent predictor of the onset of metabolic syndrome in women.

• Korean Journal of Poultry Science
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• v.29 no.4
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• pp.249-253
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• 2002

A 2 ${\times}$ 2 factorial experiment was conducted to determine the effect of cecectomy and urea supplementation on nitrogen utilization In growing chicks. Birds were either cecectomized or shamoperated and fed a 19% protein diet with or without 1% urea supplementation. All chicks were provided ad libitum access to feed and water throughout the six-day experimental period. In the cecectomized chicks, fred efficiency was significantly decreased when fed a 19% protein diet supplemented with 1% urea (P<0.05). When chicks were fed a 19% protein diet, cecectomy significantly shortened gastrointestinal passage time (GPT) of food (P<0.05). However, the GPT was significantly lengthened in chicks fed a 19% protein diet supplemented with urea (P<0.05). Regardless of diets, cecectomized chicks increased the moisture contents of the excreta (P<0.05) and feeding a 1% dietary urea also significantly increased (P<0.05). Cecectomy significantly decreased uric acid N excretion by about 30 mg per 100 g body weight per day (P<0.05) and uric acid N/ total N excretion when fed both diets (P<0.05). The present study suggests that cecectomy improves nitrogen utilization rate by decreasing uric acid excretion in growing chicks. These results are in good agreement with those obtained previously in a cecectomy study of adult chickens.