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http://dx.doi.org/10.22156/CS4SMB.2020.10.11.240

Relationship between Serum Uric Acid Levels, Insulin Resistance and Components of Metabolic Syndrome in Korean Adults  

Shin, Kyung-A (Dept. of Clinical Laboratory Science, Shinsung University)
Kim, Eun Jae (Dept. of Obstetrics and Gynecology, Seoul National University)
Publication Information
Journal of Convergence for Information Technology / v.10, no.11, 2020 , pp. 240-250 More about this Journal
Abstract
The purpose of this study was to investigate the relationship between serum uric acid levels, insulin resistance and components of metabolic syndrome. It was conducted on 4,428 adults over the age of 20 who had undergone health checkups at a general hospital in Gyeonggi-do from June 2018 to May 2020. As a result of the study, uric acid levels were higher in the metabolic syndrome subjects than normal subjects in both men and women. and the incidence of metabolic syndrome and its components was higher in the hyperuricemia group than in the normal group. Hyperuricemia was found to increase the risk of elevated blood pressure(p=0.006) and hypertriglyceridemia(p<0.001) in men and metabolic syndrome(p=0.012) and low HDL-cholesterol(p<0.001) in women. Thus, in both men and women, hyperuricemia was associated with metabolic syndrome and its components, and it was confirmed that it was an independent predictor of the onset of metabolic syndrome in women.
Keywords
Uric acid; Metabolic syndrome; Insulin resistance; Metabolic syndrome components; Hyperuricemia;
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