• Title/Summary/Keyword: 외부환경개선

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Development of Chitosan Coated Solid Lipid Nano-particles Containing 7-Dehydrocholesterol (7-디하이드로콜레스테롤을 함유한 키토산 코팅 처리 Solid Lipid Nano-particle의 개발에 관한 연구)

  • Lee Geun-Soo;Kim Tae-Hoon;Lee Chun-Il;Pyo Hyeong-Bae;Choe Tae-Boo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.2 s.51
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    • pp.141-146
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    • 2005
  • Unstable cosmetic active ingredients could rapidly break down in chemical and photochemical process. Therefore, it has become a very important issue to encapsulate active ingredient for the stabilization. 7-Dehydrocholesterol (7-DHC), a precursor of vitamin $D_3$, has been shown to increase levels of protein and mRNA for heat shock protein in normal human epidermal keratinocytes. However, topical dermal application of 7-DHC is restricted due to its poor solubility and chemical unstability. In this study, 7-DHC was incorporated into nano-emulsion (NE), solid lipid nano-particle (SLN), and chitosan coated solid lipid nano-particle (CASLN), respectively. In order to prepare NE and SLN dispersion, high-pressure homogenization at temperature above the melting point of lipid was used Hydrogenated lecithin and polysorbate 60 were used as stabilizer for NE and SLN. CASLN was prepared by high speed homogenizing after adding chitosan solution to the SLN dispersion and showed positively charged particle properties. Decomposition rate of 7-DHC in NE, SLN and CASLN was studied as a function of time at different temperature. Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) studies were performed to characterize state of lipid modification. It appeared that CASLN is the most effective to stabilize 7-DHC and may be used for a useful topical dermal delivery system.

A 12b 1kS/s 65uA 0.35um CMOS Algorithmic ADC for Sensor Interface in Ubiquitous Environments (유비쿼터스 환경에서의 센서 인터페이스를 위한 12비트 1kS/s 65uA 0.35um CMOS 알고리즈믹 A/D 변환기)

  • Lee, Myung-Hwan;Kim, Yong-Woo;Lee, Seung-Hoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.3
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    • pp.69-76
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    • 2008
  • This work proposes a 12b 1kS/s 65uA 0.35um CMOS algorithmic ADC for sensor interface applications such as accelerometers and gyro sensors requiring high resolution, ultra-low power, and small size simultaneously. The proposed ADC is based on an algorithmic architecture with recycling techniques to optimize sampling rate, resolution, chip area, and power consumption. Two versions of ADCs are fabricated with a conventional open-loop sampling scheme and a closed-loop sampling scheme to investigate the effects of offset and 1/f noise during dynamic operation. Switched bias power-reduction techniques and bias circuit sharing reduce the power consumption of amplifiers in the SHA and MDAC. The current and voltage references are implemented on chip with optional of-chip voltage references for low-power SoC applications. The prototype ADC in a 0.35um 2P4M CMOS technology demonstrates a measured DNL and INL within 0.78LSB and 2.24LSB, and shows a maximum SNDR and SFDR of 60dB and 70dB in versionl, and 63dB and 75dB in version2 at 1kS/s. The versionl and version2 ADCs with an active die area of $0.78mm^2$ and $0.81mm^2$ consume 0.163mW and 0.176mW at 1kS/s and 2.5V, respectively.

A Investigation and Analysis of Water Temperature by Juam Regulation Dam Outflow in Downstream and Suncheon Bay (주암조절지댐 방류수에 따른 하천 및 순천만 일대 수온변화 조사분석)

  • Lee, Hyeon No;Jung, Kwan Sue;Cheon, Geun Ho;Hur, Young Teck
    • Journal of Korea Water Resources Association
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    • v.48 no.6
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    • pp.501-509
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    • 2015
  • Lately multipurpose dam is required to consider various interests such as quality, ecological environment as well as flood control, water supply, hydropower generation, etc. The objective of this study is to investigation and analysis of water temperature in the areas where there are social conflicts due to cold water outflow. In this study, we monitored water temperature of Juam regulation dam, downstream river, Suncheon bay in a long term period and performed comparative analysis on a change of water temperature in downstream river and Suncheon bay by using three-dimensional numerical mode (EFDC) considering various external factors such as water outflow amount. The result of monitoring and numerical modelling indicates that effects of cold water outflow takes place from april to september. Also effects of the low temperature discharge of dam was complicatedly altered by various factors such as outflow time and amount, weather and tide level conditions etc. The result of this study can be utilized as a basic data for establishing improvement of dam operation plan to minimize negative effects of dam's cold temperature water outflow to downstream river and coastal area.

Polydiacetylene-Based Chemo-/Biosensor of Label Free System with Various Sensing Tools (다양한 감지 방법을 갖고 있는 폴리디아세틸렌 기반 비표지 화학/바이오센서)

  • Park, Hyun-Kyu;Park, Hyun-Gyu;Chung, Bong-Hyun
    • KSBB Journal
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    • v.22 no.6
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    • pp.409-413
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    • 2007
  • Polydiacetylene(PDA)-based sensors possess a number of properties that can be successfully applied for label-free detection system. PDA is one of the most attractive color-generating materials, with growing applications as sensors. Here we introduce various PDA-based devices, used as biosensor, chemosensor, thermosensor, and optoelectronics sensor. In general, PDA liposomes and films are closely packed and properly designed for polymerization via 1,4-addition reaction to form an ene-yne alternating polymer chain. PDA-based two/three dimensional structures have been used for colorimetric or fluorescent devices, sensing biological as well as chemical components. This color-generating material also present a very high charge carrier mobility, allowing its application as field-effect transistor (FET). The immobilized PDA structures or films have distinct advantages for the detection of low concentration target molecules over the aqueous solution-based detection systems. In the present review, reported detection methods by using various PDA structures are summarized with updated references.

The Analysis of Change Factors and Improvement of the Planning techniques on the Number of Floor in Multi Housing Complex Planning -Focus on Planning Index- (공동주택 층수계획 변화요인 분석과 계획기법 개선에 관한 연구 -계획지표를 중심으로-)

  • Cho, Sung-Hak
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.4
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    • pp.428-437
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    • 2017
  • Recently, local government has established a development strategy which takes into account the quality of each area, in order to solve the problems posed by poor development, hindrance of the urban landscape, the limits imposed by relevant laws, etc. However, the number of floors is an important factor which determines the urban landscape, planning density and quality of the external space. This planning factor has a very different effect according to the terrestrial circumstances, number of households, underparking ratio, green space ratio and floor area ratio. Therefore, in this study, a case analysis and case study are conducted and the correlation between each index is clarified. The conclusions of this study are follows. Firstly, flexibility should be ensured by taking into consideration the density indicators, average number of floors, and residential environmental performance measures in related laws and systems. Secondly, it is necessary to develop a wide-area planning method that extends the planning concept from the beginning of planning to neighboring blocks or cities. Thirdly, deregulation measures should be implemented, such as establishing specialized strategies for each region, and regulatory measures for encouraging different types of development.

Digital Reproduction of Mobiles (모빌의 디지털 재현)

  • Lee, Dong-Chun;Lee, Nam-Kyeong;Jung, Dae-Hyun;Kim, Chang-Tae;Lee, Dong-Kyu;Bae, Hee-Jung;Baek, Nakhoon;Lee, Jong-Won;Ryu, Kwan-Woo
    • Journal of KIISE:Computer Systems and Theory
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    • v.28 no.9
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    • pp.415-423
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    • 2001
  • Recently, there are many attempts to reproduce real world fine art pieces in digital forms. The digital representations are convenient to store and/or transmit. In contrast, mobiles, or moving sculptures, such as those designed by Alexander Calder cannot to reproduced realistically by usual reproduction techniques. Since mobiles are originally designed to generate motions in response to external forces applied to it, people could not fully enjoy them through photographs or static images. We present a virtual mobile system where use can easily control the mobile and can feel the impressions that the artist originally intended to provide. A real-world mobile is reconstructed in a three-dimensional physically-based model. and then virtual wind is generated to give motions to it. The motions of the mobile are generated by constraint dynamics and impulse dynamics techniques, which are modified to fully utilize the characteristics of the mobile, and finally give interactive displays on the PC platforms. The techniques presented can easily be extended to simulate other interactive dynamics systems.

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An Analysis of Locational Characteristics and User Behavior of Neighborhood Parks in Central Business District (중심상업지역 근린공원의 공간적 입지특성과 이용행태 분석)

  • Choi, Chul-Hyun;Woo, Young-Sook;Jung, Sung-Gwan
    • Journal of the Korean Association of Geographic Information Studies
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    • v.18 no.1
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    • pp.25-47
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    • 2015
  • The user behaviors in the parks around the commercial area may have different characteristics in comparison with the behaviors in typical neighborhood parks because they may be affected by nearby commercial facilities. The purpose of this study is to explore the characteristics of park users'behavior considering adjacent environments in the neighborhood parks located in central business district of Daegu and to suggest improvements and complements for the construction of new parks and remodeling current parks. According to the results, the land values were high and the percentage of deteriorated buildings was low around Gukchae Reward Movement Memorial Park and 2.28 Central Memorial Park. However, the commercial facilities were entirely declined along with a drop in land values around Gyeongsang-gamyeong Park and old people used this park more than young people. In terms of the purpose of park use, users of three parks had indirect behavior patterns related near commercial facilities rather than using directly park facilities and the age groups of park users were similar to the user groups of nearby commercial facilities. Also, the determinant factors of satisfaction with park use were varied depending on the difference of age groups of park users and park characteristics. Therefore, it is necessary to consider the effects of user age groups according to the changes of environment around parks for the construction and organization of parks.

The Effect of Jeju Wild Ginseng Extracts on Skin Barrier via Serine-Palmitoyltransferase (제주산양산삼이 세린-팔미토일 전이효소(Serine-Palmitoyltransferase)를 통해 피부 장벽에 미치는 효과에 대한 연구)

  • Kim, Hyo Min;Lee, Jung No;Kim, Jae Moon;Kim, Sung Kyu;Park, Sung-Min
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.2
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    • pp.119-126
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    • 2016
  • Skin is the largest organ that protects the body from the external environmental factors such as smog, cigarette smoke, UV. Protective skin barrier is composed with keratinizational keratinocytes and intercellular lipids such as ceramides, cholesterols and fatty acids combined by the lamellar liquid crystal structure. In this research, we confirmed that the Jeju wild ginseng (JWG) extracts dose-dependently increased the expression of serine-palmitoyltransferase (SPT) protein which is associated with ceramide biosynthesis. In addition, emulsion containing 5% JWG extract was applied on skin of human volunteers for 2 weeks and then significantly reduced transepidermal water loss (TEWL) compared to that of control group. As a results, JWG extract increased the biosynthesis of ceramides that is the key components of the skin lipid through enhancing expression of SPT. In addition, JWG extract reduced TEWL resulting in improvement of skin barrier function. In this context, we suggest that JWG extract could be used as a skin barrier enhancer and moisturing agents in cosmetic fileds.

A Study on safety improvement of Underground wall construction to Design for Safety (설계안전성검토를 통한 지하외벽공사의 안전개선 연구)

  • Ji, Kyung-Hwan;Choi, Byong-Jeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.4
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    • pp.56-68
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    • 2019
  • Safety-conscious design on site is required for site constructions because of the introduction of the design for safety, but it still leaves much to be desired. This study compared the site where the design was applied and the site where it was not applied. The applied case examined the underground wall construction during frame construction, which corresponds to the skeleton of the building construction. The underground wall construction is quite risky due to the exposure to exterior environments and involvement of various stages, such as scaffolding, formwork, reinforcing work, and concrete casting work. Therefore, the risk factors for each stage were identified and a risk assessment was carried out to select an alternative method to reduce the risk. The risk factors of the selected alternative construction method were also identified and a risk assessment was conducted. The risk assessment weight was calculated by comparing the site where the construction method was applied and the site where it was not, explaining the necessity of the design for safety in reducing the risk. In addition, an actual case where an alternative construction method was used was studied to highlight the necessity for a design for safety.

A Study on anthropology of education of 'character' (인성과 교육의 관계적 의미 고찰: '문질빈빈' 인성 고찰을 통한 교육인류학적 함의 탐색)

  • Shin, Hyun-Seok;Kim, Sang-cheol
    • (The)Korea Educational Review
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    • v.23 no.2
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    • pp.131-155
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    • 2017
  • In this study, I examine what is called character. It is to establish what constitutes a relationship between life, culture, and education. In addition, I try to explore the possibility of anthropology of education as an academic basis for character education by using the way of '문 질빈빈(文質彬彬)'. As a result of the study, 'character' in terms of '문(culturality)' aspect implies the qualities, the nature, the disposition, and the meaning of virtue. A 'character education' can be seen in school education as a moral consideration, considering the social context, such as the ability to live harmoniously. In terms of '질(naturality)', I will look at both the innate aspect of the character and the acquired aspect through the 'character' which is the essence of character. Character is the concept of both parties, and if it is influenced by an external environment, one can seek better ways to improve the chances of improvement through education. Furthermore, the role of education is inevitably required in order to achieve the goal of 'lesser human being' to 'better human being'. Home and school education can have a positive impact on the character. An honest mind about humanity among family members is the right character. The importance of humanity is considered as a value to be recognized and protected in our society because the logic that it protects the family by character and helps to maintain the social order influences to the legal culture tradition of the modern. Therefore, the academic approach through anthropology of education has sufficient value of trial study for exploring the relationship between character, education, and culture for teachers and learners, and is appropriate for providing an academic foundation.