• The Korean Journal of Nuclear Medicine
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• v.29 no.4
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• pp.451-459
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• 1995

Thirty-eight patients with metastatic well-differentiated thyroid carcinoma treated with 200mCi $^{131}I$ were studied. There were false negative serum thyroglobulin values during TSH suppression or at anti-thyroglobulin antibody(+) and discrepancies between findings of whole body scan and serum thyroglobulin level. After one to five cycles of 200mCi $^{131}I$ therapy, complete remission and partial remission were achieved at 5.3% and 57.9%, respectively. We concluded that all of serum thyroglobulin, TSH, anti-thyroglobulin antibody, $^{131}I$ or $^{123}I$ whole body scan were necessary in follow up of metastatic well-differentiated thyroid carcinoma. Also, if there was no response after repetitive 200mCi $^{131}I$ therapy, higher doses of $^{131}I$ therapy should be considered.

• Korean Journal of Head & Neck Oncology
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• v.14 no.2
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• pp.214-219
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• 1998

Objectives: To assess the effectiveness of the low-dose(30mCi) I-131 ablation therapy for remnant thyroid tissue following total thyroidectomy for differentiated thyroid cancer. Methods: Between March 1995 and December 1997, forty-eight patients were given ablative doses(30mCi) of I-131 after total thyroidectomy for differentiated thyroid cancer in the presence of I-131 uptake in remnant thyroid tissue. Effective ablation of remnant thyroid tissue was determined by following I-131 whole body scan. if remnant thyroid tissue remained, we repeated the same management at 6 months interval. Results: Thirty-eight(79.1%) patients had papillary, 8(16.7%) follicular, 1(2.1%) medullary and 1(2.1%) Hurthle cell type cancer. Forty-eight patients underwent total thyroidectomy, among those central neck dissection was performed in 35 cases, and modified radical neck dissection in 14 cases. Postoperative complication developed in 8 cases, which included 4 cases of transient hypoparathyroidism, 1 case of permanent hypoparathyroidism, 2 cases of transient recurrent laryngeal nerve palsy, and 1 case of wound hematoma. There were significant remnant thyroid tissue in 46 cases(95.8%) of patients after total thyroidectomy, which could be ablated by low dose(30mCi) I-131. There were no statistical difference between operative procedures and number of treatment of I-131. Conclusions: These results suggested that repeated low-dose(30mCi) I-131 therapy would be needed, therefore, high -dose I-131 therapy could be considered as ablation therapy for the remnant thyroid tissue after total thyroidectomy for differentiated thyroid cancer.

• Journal of Adhesion and Interface
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• v.14 no.1
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• pp.13-20
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• 2013

Palladium plays a pivotal role in the production of dental and medicinal devices, medicinal substances, jewellery, automobile and high-performance adhesives. Despite the frequent and fruitful use of such reactions, one major setback is the high level of palladium in the resultant compounds which can harm the human body. Among the palladium species, $PdCl_2$ is the most toxic. As a consequence it is desirable to detect the $Pd^{2+}$ cations by fluorescence spectra because it can provide an operationally simple and cost-effective detection method together with high sensitivity and selectivity. Herein, an ${\alpha}$-carbonyl substituted pyrene derivative, ${\gamma}$-oxo-1-pyrenebutyric acid (OPBA), was demonstrated to be a highly sensitive and selective fluorescent probe for $Pd^{2+}$ among the metal cations examined in aqueous solutions.

• The Research Journal of the Costume Culture
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• v.13 no.2 s.55
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• pp.269-279
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• 2005

Okso, Keun Seob($1671\sim1759$) was descended from a noble family of Noreun(노론) and learned from his uncle, Keun Sang-ha who is a disciple of Song Si-Yeol, Kim Chang-hyeub and Kim Chang-heub. His $\lceil$Oksoko$\rfloor$ remains in the form of a transcription or a lithographic printing, and documents on 'Hakchangeui' are recorded in jabeui(잡의), Euijedogi(의제도기), which is a part of it. He left Seoul in 1714, settled in Chungpung, journeyed to many places, including the Hwang river area and Jecheon and led a literary and artistic life as Sadaebu(사대부), which was written in a collection of his works where the record about 'Hakchangeui', the most suitable clothes for the life of a retired scholar remains today to express one part of his life. This study introduces data about Hakchangeui written in $\lceil$Oksoko$\rfloor$, pursues the reason why Okso, Keun Seob told about it and intends to embody the figure of Hakchangeui based on the system, measure, material, and sewing method according to the records in a collection. Hakchaneui described in $\lceil$Oksoko$\rfloor$ reveals a structure that is different from old Hakchaneui, showing characteristics like the following. It is a Sadaebu's costume for field amusement in which the length of a former part is longer than that of a later part and the side seam of a garment rips. Black Yeon is attached to the white texture. Yeon widths of Git(collar), Sugu and Gil are varied, respectively. Yeon's figure attached to Gil and Somaejindong is a mountain. Git is Bangryeong and link parts between Git and Gil is connected with Sangchim. This Hakchangeui is considered to playas a gown because it has no string or support to adjust his dress. Especially we can identify that Hwayanggun(화양건) was used in this Hakchangeui.

• Journal of Aquaculture
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• v.10 no.1
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• pp.9-15
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• 1997

The pathogenic organisms occurred in cultured marine fishes in Kamak Bay were investigated from March to November in 1993. The samples were collected at 7 sampling stations once a month. Nine species of pathogenic organisms (Vibrio sp., Edwardsiella sp., Flexibacter sp., Streptococcus sp., Micrococcus sp., Caligus sp., Trichodina sp., Lymphocystis and Staphylococcus sp.) were identified as pathogenic organisms from four different species of fish (Sebastes schlegeli, Paralichthys olivaceus, lateolabrax japonicus and Pagrus major) collected in the study areas. Most of pathogenic organisms were found at over 20^{\circ}C$ of sea water temperature from June to October in 1993. On the test of drug sensitivity, Vibrio sp. (KS-9303) was sensitive to oxytetracycline and chloramphenicol ; Edwardsiella sp. (KP-9315) to oxytetracycline ; Flexibacter sp. (KP-9318) to oxytetracycline, chloramphenicol and oxolinic acid ; Streptococcus sp. (KP-9319) to erythromycin, chlorampheicol and oxytetracycline. However, all these 4 isolated bacteria were resistant to ampicilin, steptomycin, sulfamethoxazole and nitrofurazone.

• Journal of the Korean Chemical Society
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• v.33 no.1
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• pp.90-96
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• 1989

A new series of $dioxo-di-{\mu}-oxo-dimolybdate(V)(*image)$, has been prepared by the reaction of pyridinum oxoisothiocyanato-molybdate(V) with 1, 6-diaminohexane-N, N, N', N'-tetraacetic acid derivatives containing amine carboxyl groups. The properties and possible molecular structure of these complexes were discussed by elemental analysis, spectroscopic studies and magnetic susceptibility measurements. The infrared spectra of these complexes show two strong Mo=$O_t$ stretching modes in the $900-965cm^{-1}$, MoO$_2$Mo stretching bands at around 450∼500 and $740-765 cm^{-1}$ to symmetrical and asymmetrical O-bridge stretching, a coordinated $COO^-$ asymmetrical band in the $1600-1635 cm^{-1}$. The complexes synthesized were yellow or orange and diamagnetic.

• Journal of the Korean Chemical Society
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• v.31 no.6
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• pp.520-526
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• 1987

A new series of $dioxo-di-\mu-oxo-dimolybdate(V)$, has been prepared by reaction of pyridinum oxoisothiocyantomolybdate (V) with iminodiacetic acid derivatives containing amine carboxyl groups. The properties and possible molecular structure of these complexes were discussed by elemental analysis, spectroscopic studies and magnetic susceptibility measurements. The infrared spectra of these complexes all show two strong $Mo=O_t$ stretching bands in the 900∼$980cm^{-1}$, $MoO_2Mo$ very prominent strectching bands at around 410~425 and 735~$750cm^{-1}$ to symmetrical and asymmetrical O-bridge stretching, a coordinated $coo^-$ asymmetrical band in the 1585∼$1,640cm^{-1}$. Also, d-d transition of molybdenyl complexes corresponding to $^2B_2{\to}^2B_1$ occured in the 24,800~$28,000cm^{-1}$ region, charge transfer transition corresponding to ligand-to-molybdenum in the 32,500~33,800, 42,000~$47,500cm^{-1}$ region. The complexes synthesized were yellow or orange and diamagnetic.

• The Korean Journal of Nuclear Medicine
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• v.6 no.1
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• pp.41-49
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• 1972

The author observed the thyroid $^{131}I$ uptake rate using an intradermal injection method. The amount of activity remaining at the site of intradermal injection of 0.1 ml. of $5{\mu}Ci.\;of\;^{131}I$ in physiologic saline was measured in 79 cases of hyperthyroidism and in 24 cases of hypothyroidism. The cases had been confirmed by clinical and laboratory findings, at the department of medicine, (radioisotope clinic) Pusan National University Hospital. Twenty-nine normal control cases were examined currently by the same technique during the period from Jan. 1967 to June 1970. The following results were obtained: 1. In the normal group, the ranges and mean values of the thyroid uptake 10, 15, 20, 25, 30 and 60 minutes after intradermal $^{131}I$ injection, were $0{\sim}10%(6.33{\pm}1.63),\;0{\sim}15%(7.83{\pm}2.12),\;0{\sim}15%(8.46{\pm}2.82),\;5.1{\sim}20%(9.66{\pm}2.27),\;5.1{\sim}25%(10.47{\pm}2.52),\;5.1{\sim}30%(13.03{\pm}4.42)$. 2. In the hyperthyroid group, the ranges and mean values of the thyroid uptake 10, 15, 20, 25, 30 and 60 minutes after intradermal $^{131}I$ injection were $5.1{\sim}45%(22.25{\pm}7.04),\;10.1{\sim}50%(28.32{\pm}6.67),\;15.1{\sim}55%(34.78{\pm}11.63),\;15.1{\sim}65%(37.95{\pm}7.72),\;20.1{\sim}65%(41.49{\pm}0.05)\;and\;20.18096(48.71{\pm}12.51)$. 3. In the hypothyroid group, he ranges of thyroid $^{131}I$ uptake by intradermal $^{131}I$ injection at 10, 15, 20, 25, 30 and 60 minutes lay between 0 and 10%, and the the mean values were $4.23{\pm}1.76,\;5.08{\pm}1.68,\;5.56{\pm}1.70,\;6.02{\pm}1.75,\;6.37{\pm}1.91\;and\;6.95{\pm}2.07$. 4. In conclusion, thyroid function test using an intradermal injection method in cases of hyperthyroidism, showed characteristic values which seemed to be of diagnostic significance.

• Applied Chemistry for Engineering
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• v.34 no.2
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• pp.175-179
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• 2023

Herein we present a tested aqueous based redox flow battery (RFB) that employs phosphomolybdic acid and ferrocyanide as the negative and positive active species in an aqueous sodium hydroxide solution. The different concentrations of NaOH solution, such as 1.0, 1.2, 1.4, 1.5, and 1.6 M, were prepared for checking the electrochemical properties and stability. The NaOH concentration as a supporting electrolyte in the negative species appears to play an important role in the electrochemical properties of phosphomolybdic acid. Moreover, the optimum value of the concentration is necessary for the best performance. The resistance of the electrolyte decreased with increasing the concentration up to 1.5 M and then increased to 1.6 M. Hence, the decrease in electrolyte resistance appears to greatly influence the energy efficiency, which is improved by increasing the concentration of NaOH. In addition, the 1.5 M NaOH solution appears to be the concentration required for optimum performance.

• Nuclear Medicine and Molecular Imaging
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• v.41 no.3
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• pp.226-233
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• 2007

Purpose: Dual reporter gene imaging has several advantages for more sophisticated molecular imaging studies such as gene therapy monitoring. Herein, we have constructed hepatoma cell line expressing dual reporter genes of sodium iodide symporter (NIS) and enhanced green fluorescence protein (EGFP), and the functionalities of the genes were evaluated in vivo by nuclear and optical imaging. Materials and Methods: A pRetro-PN vector was constructed after separating NIS gene from pcDNA-NIS. RSV-EGFP-WPRE fragment separated from pLNRGW was cloned into pRetro-PN vector. The final vector expressing dual reporter genes was named pRetro-PNRGW. A human hepatoma (HepG2) cells were transfected by the retrovirus containing NIS and EGFP gene (HepG2-NE). Expression of NIS gene was confirmed by RT-PCR, radioiodine uptake and efflux studies. Expression of EGFP was confirmed by RT-PCR and fluorescence microscope. The HepG2 and HepG2-NE cells were implanted in shoulder and hindlimb of nude mice, then fluorescence image, gamma camera image and I-124 microPET image were undertaken. Results: The HepG2-NE cell was successfully constructed. RT-PCR showed NIS and EGFP mRNA expression. About 50% of cells showed fluorescence. The iodine uptake of NIS-expressed cells was about 9 times higher than control. In efflux study, $T_{1/2}$ of HepG2-NE cells was 9 min. HepG2-NE xenograft showed high signal-to-background fluorescent spots and higher iodine-uptake compared to those of HepG2 xenograft. Conclusion: A hepatoma cell line expressing NIS and EGFP dual reporter genes was successfully constructed and could be used as a potential either by therapeutic gene or imaging reporter gene.