• Childhood Kidney Diseases
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• v.11 no.2
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• pp.152-160
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• 2007

Twenty-six renal allograft biopsies which showed acute rejection and had renal capsule and medulla in the same specimen were selected in order to compare the severity of acute rejection between superficial cortex, deep cortex and medulla. Disregarding the mid cortical region, the superficial cortex was considered as being one-third of the distance from the renal capsule to the medulla and the deep cortex as being that one-third of the cortex which was adjacent to the medulla. Using semiquantitative histologic analysis the following parameters were compared in superficial cortex, deep cortex, and medulla: interstitial inflammation, edema, tubulitis, and acute tubulointerstitial rejection grade. Also, the presence of lymphocyte activation and polymorphonuclear leukocytes was evaluated. Significantly greater histologic changes of acute rejection were found in the deep cortex vs. supeficial cortex for the following parameters: interstitial inflammation(P=0.013), edema (P=0.023) and tubulointerstitial rejection grade(P=0.016). These findings support the view that biopsies in which deep cortex is not included may result in underestimation of the severity of renal allograft rejection.

• The Korean Journal of Applied Statistics
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• v.29 no.1
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• pp.61-73
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• 2016

We consider the wild bootstrap Ljung-Box (LB) test for autocorrelation in residuals of fitted multivariate time series models. The asymptotic chi-square distribution under the IID assumption is traditionally used for the LB test; however, size distortion tends to occur in the usage of the LB test, due to the conditional heteroskedasticity of financial time series. In order to overcome such defects, we propose the wild bootstrap LB test for autocorrelation in residuals of fitted vector autoregressive and error correction models. The simulation study and real data analysis are conducted for finite sample performance.

• Journal of the Korea Society of Computer and Information
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• v.10 no.1 s.33
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• pp.113-124
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• 2005

The work of investigation in the laboratory medicine includes various kinds of investigations and microbes and it is too complicated to draw needed results in time. So, we aim to improve work performance of the laboratory medicine. For this study, we implemented the scheduling system in microbe investigation using agent environment and the workflow management system to manage the schedule of investigation, and the query system to check the schedule. And preliminary report and final report of microbe investigation can be announced automatically using agent. The scheduling system implemented could identify the lack or waste of resources and thus enable efficient management and distribution of resources. The query system could check the schedule and retrieve the Processing status in short time, enabled the automated report, and reduced possible interrupts and the delay of work that can be occurred in confirming process. It also enables users to access from local and remote sites. Also, this system can reduce the conflicts among People that may occur in unexpected situations because it enables doctors to confirm those situations such as the malfunction of instrument and the lack of agar or reagent, and the efficiency of work process can be expected.

• Journal of the Korea Society of Computer and Information
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• v.17 no.9
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• pp.127-138
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• 2012

In this paper, we present a tool (named VMBootFailMonitor) to detect and analyze a failure of a VM boot creation caused by faults on virtual disks of a Xen-based VM. Also, we presents an architecture and detail analysis process of the virtual disk faults in our tool. Especially, VMBootFailMonitor provides a causual analysis result for a case of VM creation failure based on three modules which performs virtual disk analysis, virtualized system analysis and system log analysis. We also support a comparison result between boot times of normal VMs and fault detection times of VM creation based on abnormal virtual disks. At result, our tool detects VM boot failures (3~6 seconds) within normal VM boot times (8~16 seconds).

• The Transactions of the Korea Information Processing Society
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• v.3 no.2
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• pp.339-347
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• 1996

object-oriented programming is used to develop next-generation telecommu- nications services running on the distributed processing environment. In order to test these services efficiently at the system-level during not only in the development phase but also in the operation phase, we define an embedded monitor service within the infrastructure to monitor the operation of the distributed programs, and describe a system-level test mechanism based on the monitor service. By separating the function of monitor server which monitors operations of objects and collects monitored data and that of tester which makes analysis and decides the sequence of test events, the invasive effect of monitoring can be minimized. At the same time, accurate diagnosis on the system can be achieve by exploiting the test mechanism. The mechanism, as a core component for the implementation of real-time fault-tol-erant systems, is applicable to general-purpose distributeded systems as well.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.4
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• pp.111-116
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• 2018

In this thesis, the range of motion of the joint was measured using a flexible sensor without using a goniometer, and the measured values were transferred to a smart device. Current range of joint motion measurement is measured by a person using a goniometer. Since the method of measuring by a person is different according to the measuring method and position of the measuring person, it is difficult to make consistent measurement, and an error may occur. The sensor for measurement is a flexible sensor that measures the resistance value that changes according to the movement of the joint. The sensed value can be transmitted to the smart device wirelessly through the ROM sensor node. Also, the sensed analog values were converted to digital values using an ADC. The converted value can be transmitted to the smart device wirelessly through the sensor node. The developed ROM measuring device can perform more consistent measurement than the measurement using general articulator and real time monitoring by interlocking with smart device, so that rapid diagnosis according to the movement of the joint can help the patient's rapid treatment and rehabilitation medical advancement will be.

• The Journal of Korean Academy of Prosthodontics
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• v.49 no.4
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• pp.341-345
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• 2011

Genetic association study has been progressed in medicine along with advance in genetic technology. It focused on the individual differences in genotype due to errors occurring during DNA duplication, which can cause vulnerability to specific diseases. Polymorphism defines the varieties in phenotype due to those genetic variations. Polymorphism due to change in one DNA base sequence is called as a Single Nucleotide Polymorphism. In the near future, the evaluation of relative risk to specific disease according to SNP will be essential part of fundamental of medicine for the diagnosis, treatment and prevention. Dental caries and periodontal diseases has been first subject to genetic association study in dentistry and broaden out to other areas like bone formation and resorption. This article presents the current state of genetic association study and its application to dentistry.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2005.05a
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• pp.198-201
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• 2005

DNA microarray 칩은 신약 개발, 유전적 질환 진단, Bio-molecular 상호작용 연구, 유전자의 기능연구 등 폭넓게 사용되고 있다. 이 논문은 cDNA mimcroarray 데이터를 분석하기 위한 웹형태의 시스템 개발에 대한 내용을 다룬다. 하나의 cDNA microarray에는 수 백에서 수 만개의 유전자가 심어져 있으며, 데이터를 분석할 때 대량의 데이터와 다양한 형태의 오류로 인해서 데이터간의 차이를 보정하는 분석 도구와 통계적 기법들이 사용되어야 한다. 본 논문에서는 가상 칩 뷰어를 이용하여 실제 microarray 데이터의 foreground intensity에서 백그라운드의 intensity를 제거하여 일반화된 칩 이미지를 생성한다. 이 가상 칩 뷰어는 여러 가지 필터효과와 서로 다른 두 형광의 차이를 조정하는 global normalization 기법을 사용하여 발현 유전자 분석을 시각적으로 할 수 있고, 중복된 마이크로어레이 칩 데이터를 통하여 시간이 많이 걸리는 분석전 칩의 유효성을 검토할 수 있다. 칩 데이터의 normalization을 위한 통계 방법으로 R 통계 도구와 linear 모델을 사용하여 microarray 칩의 유전자 발현 양상을 분석한다. 통계적 방법을 사용하지 않은 데이터를 추출, 이 데이터의 패턴 그래프 그리고 발현 레벨을 분류하여 마이크로어레이의 각 스팟의 유효성 검토의 정확성을 높였다. 이 시스템은 칩의 유효성 검토, 스팟의 유효성 검토, 유전자 선정에 대해 분석의 용이성과 정확성을 높일 수 있었다.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.40 no.12
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• pp.1040-1047
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• 2012

This paper presents a fault diagnosis algorithm of control surfaces of small fixed-wing aircraft to reduce maintenance cost or to improve repair efficiency by estimation of fault occurrence or part replacement periods. The proposed fault diagnosis algorithm consists of ANPSD (Averaged Normalized Power Spectral Density), PCA (Principle Component Analysis), and GC (Geometric Classifier). ANPSD is used for frequency-domain vibration testing. PCA has advantage to extract compressed information from ANPSD. GC has good properties to minimize errors of the fault detection and isolation. The algorithm was verified by the accelerometer measurements of the scaled normal and faulty ailerons and the test results show that the algorithm is suitable for the detection and isolation of the control surface faults. This paper also proposes solutions for some kind of implementation problems.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.27 no.6
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• pp.1331-1345
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• 2017

Binary instrumentation has been developed for monitoring and debugging executables without their source codes. Previous efforts on the binary instrumentation are mainly focused on its capability and accuracy, but not on efficiency for practical application. In particular, criteria and measurement methodologies for evaluating and comparing the efficiency of binary investigation tools and algorithms do not estimated yet. In this paper, we propose the instrumentation primitives which are a unit functionality and measurement methodology. Through the empirical experiments by adopting the proposed methodology on DynamoRIO and Pin, we show the feasibility of the proposal.