• Title/Summary/Keyword: 영의 계수

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The Design Of Microarray Classification System Using Combination Of Significant Gene Selection Method Based On Normalization. (표준화 기반 유의한 유전자 선택 방법 조합을 이용한 마이크로어레이 분류 시스템 설계)

  • Park, Su-Young;Jung, Chai-Yeoung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.12
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    • pp.2259-2264
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    • 2008
  • Significant genes are defined as genes in which the expression level characterizes a specific experimental condition. Such genes in which the expression levels differ significantly between different groups are highly informative relevant to the studied phenomenon. In this paper, first the system can detect informative genes by similarity scale combination method being proposed in this paper after normalizing data with methods that are the most widely used among several normalization methods proposed the while. And it compare and analyze a performance of each of normalization methods with multi-perceptron neural network layer. The Result classifying in Multi-Perceptron neural network classifier for selected 200 genes using combination of PC(Pearson correlation coefficient) and ED(Euclidean distance coefficient) after Lowess normalization represented the improved classification performance of 98.84%.

Usefulness Evaluation of Artifacts by Bone Cement of Percutaneous Vertebroplasty Performed Patients and CT Correction Method in Spine SPECT/CT Examinations (척추 뼈 SPECT/CT검사에서 경피적 척추성형술 시행 환자의 골 시멘트로 인한 인공물과 CT보정방법의 유용성 평가)

  • Kim, Ji-Hyeon;Park, Hoon-Hee;Lee, Juyoung;Nam-Kung, Sik;Son, Hyeon-Soo;Park, Sang-Ryoon
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.49-61
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    • 2014
  • Purpose: With the aging of the population, the attack rate of osteoporotic vertebral compression fracture is in the increasing trend, and percutaneous vertebroplasty (PVP) is the most commonly performed standardized treatment. Although there is a research report of the excellence of usefulness of the SPECT/CT examination in terns of the exact diagnosis before and after the procedure, the bone cement material used in the procedure influences the image quality by forming an artifact in the CT image. Therefore, the objective of the research lies on evaluating the effect the bone cement gives to a SPECT/CT image. Materials and Methods: The images were acquired by inserting a model cement to each cylinder, after setting the background (3.6 kBq/mL), hot cylinder (29.6 kBq/mL) and cold cylinder (water) to the NEMA-1994 phantom. It was reconstructed with Astonish (Iterative: 4 Subset: 16), and non attenuation correction (NAC), attenuation correction (AC+SC-) and attenuation and scatter correction (AC+SC+) were used for the CT correction method. The mean count by each correction method and the count change ratio by the existence of the cement material were compared and the contrast recovery coefficient (CRC) was obtained. Additionally, the bone/soft tissue ratio (B/S ratio) was obtained after measuring the mean count of the 4 places including the soft tissue(spine erector muscle) after dividing the vertebral body into fracture region, normal region and cement by selecting the 20 patients those have performed PVP from the 107 patients diagnosed of compression fracture. Results: The mean count by the existence of a cement material showed the rate of increase of 12.4%, 6.5%, 1.5% at the hot cylinder of the phantom by NAC, AC+SC- and AC+SC+ when cement existed, 75.2%, 85.4%, 102.9% at the cold cylinder, 13.6%, 18.2%, 9.1% at the background, 33.1%, 41.4%, 63.5% at the fracture region of the clinical image, 53.1%, 61.6%, 67.7% at the normal region and 10.0%, 4.7%, 3.6% at the soft tissue. Meanwhile, a relative count reduction could be verified at the cement adjacent part at the inside of the cylinder, and the phantom image on the lesion and the count increase ratio of the clinical image showed a contrary phase. CRC implying the contrast ratio and B/S ratio was improved in the order of NAC, AC+SC-, AC+SC+, and was constant without a big change in the cold cylinder of the phantom. AC+SC- for the quantitative count, and AC+SC+ for the contrast ratio was analyzed to be the highest. Conclusion: It is considered to be useful in a clinical diagnosis if the application of AC+SC+ that improves the contrast ratio is combined, as it increases the noise count of the soft tissue and the scatter region as well along with the effect of the bone cement in contrast to the fact that the use of AC+SC- in the spine SPECT/CT examination of a PVP performed patient drastically increases the image count and enables a high density of image of the lesion(fracture).

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Fit of the number of insurance solicitor's turnovers using zero-inflated negative binomial regression (영과잉 음이항회귀 모형을 이용한 보험설계사들의 이직횟수 적합)

  • Chun, Heuiju
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.5
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    • pp.1087-1097
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    • 2017
  • This study aims to find the best model to fit the number of insurance solicitor's turnovers of life insurance companies using count data regression models such as poisson regression, negative binomial regression, zero-inflated poisson regression, or zero-inflated negative binomial regression. Out of the four models, zero-inflated negative binomial model has been selected based on AIC and SBC criteria, which is due to over-dispersion and high proportion of zero-counts. The significant factors to affect insurance solicitor's turnover found to be a work period in current company, a total work period as financial planner, an affiliated corporation, and channel management satisfaction. We also have found that as the job satisfaction or the channel management satisfaction gets lower as channel management satisfaction, the number of insurance solicitor's turnovers increases. In addition, the total work period as financial planner has positive relationship with the number of insurance solicitor's turnovers, but the work period in current company has negative relationship with it.

Influence of Temperature on Chloride Ion Diffusion of Concrete (콘크리트의 염화물이온 확산성상에 미치는 온도의 영향)

  • So, Hyoung-Seok;Choi, Seung-Hoon;Seo, Chung-Seok;Seo, Ki-Seog;So, Seung-Young
    • Journal of the Korea Concrete Institute
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    • v.26 no.1
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    • pp.71-78
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    • 2014
  • The long term integrity of concrete cask is very important for spent nuclear fuel dry storage system. However, there are serious concerns about early deterioration of concrete cask from creaking and corrosion of reinforcing steel by chloride ion because the cask is usually located in seaside, expecially by combined deterioration such as chloride ion and heat, carbonation. This study is to investigate the relation between temperature and chloride ion diffusion of concrete. Immersion tests using 3.5% NaCl solution that were controlled in four level of temperature, i.e. 20, 40, 65, and $90^{\circ}C$, were conducted for four months. The chloride ion diffusion coefficient of concrete was predicted based on the results of profiles of Cl- ion concentration with the depth direction of concrete specimens using the method of potentiometric titration by $AgNO_3$. Test results indicate that the diffusion coefficient of chloride ion increases remarkably with increasing temperature, and there was a linear relation between the natural logarithm values of the diffusion coefficients and the reciprocal of the temperature from the Arrhenius plots. Activation energy of concrete in this study was about 46.6 (W/C = 40%), 41.7 (W/C = 50%), 30.7 (W/C = 60%) kJ/mol under a temperature of up to $90^{\circ}C$, and concrete with lower water-cement ratio has a tendency towards having higher temperature dependency.

Monitoring Wheat Growth by COSMO-SkyMed SAR Images (COSMO-SkyMed SAR 영상을 이용한 밀 생육 모니터링)

  • Kim, Yihyun;Hong, Sukyoung;Lee, Kyungdo;Jang, Soyeong;Lee, Hoonyol;Oh, Yisok
    • Korean Journal of Remote Sensing
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    • v.29 no.1
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    • pp.35-43
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    • 2013
  • We analyzed the relationships between backscattering coefficients of wheat measured by COSMO-SkyMed SAR and biophysical measurements such as biomass, vegetation water content, and soil moisture over an entire wheat growth period. Backscattering coefficients increased until DOY 129 and then decreased along with fresh weight, dry weight, and vegetation water content. Correlation analysis between backscattering and wheat growth parameters revealed that backscatter correlated well with fresh weight (r=0.88), vegetation water content (r=0.87), and dry weight (r=0.80), while backscatter did not correlated with soil moisture (r=0.18). Prediction equations for estimation of wheat growth parameters from the backscattering coefficients were developed.

Numerical Simulation of Immiscible Water-Gas Simultaneous Flow in the absence of Capillary Force in a Single Fracture (단일절리에서 모세관압을 고려하지 않은 불혼합성 물과 가스의 동시거동 해석)

  • 한일영;서일원
    • Journal of Soil and Groundwater Environment
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    • v.6 no.2
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    • pp.69-81
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    • 2001
  • The constitutive relation among capillary pressure, saturation and relative permeability should be predetermined in order to simulate immiscible water-gas flow in porous media. The relation between saturation and relative permeability becomes more important when the capillary force can be disregarded and viscous friction force governs the flow. In this study, a 2-dimensional finite difference numerical model was developed, in which the variation of viscosity with pressure and that of relative permeability with water saturation can be treated. Seven cases of parallel plate tests were performed in order to obtain the characteristic equation of relative permeability which would be used in. the developed numerical model. It was not possible, however, to match the curves of relative permeability from the plate tests with the existing emperical models. Consequently a logistic equation was proposed as a new emperical model. As this model was composed of the parameter involving aperture size, any aperture size of fracture can be applied to the model. For the purpose of verification, the characteristic equation of relative permeability was applied to the developed numerical model and the computed results were compared with those of plate test. As a result of application of numerical model, in order to check the field applicability, to single fracture surrounding an underground storage cavern, the simultaneous flow of water and propane gas was able to be simulated properly by the model.

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An Implementation of Temperature Independent Bias Scheme in Voltage Detector (온도에 무관한 전압검출기의 바이어스 구현)

  • Moon, Jong-Kyu;Kim, Duk-Gyoo
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.39 no.6
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    • pp.34-42
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    • 2002
  • In this paper, we propose a temperature independent the detective voltage source in voltage detector. The value of a detective voltage source is designed to become m times of silicon bandgap voltage at zero absolute temperature. By properly choosing the temperature coefficient of diode, the temperature coefficient of a concave voltage nonlinearities generated by the ${\Delta}V_{BE}$ section of diode between base and emitter of transistors with a different area can be summed with convex nonlinearities the $V_{BE}$ voltage to achieve the near zero temperature coefficient of the detective voltage source. We designed that the value of a detective voltage can be varied by ${\Delta}V_{BE}$, the $V_{BE}$multiplier circuit and resistor. In order to verify the performance of a proposed detective voltage source, we manufactured the voltage detector IC for 1.9V which is fabricated in $6{\mu}m$ Bipolar technology and measured the operating characteristics, the temperature coefficient of a detective voltage. To reduce the deviation of a detective voltage in the IC process step, we introduced a trimming technology, ion implantation and an isotropic etching. In manufactured IC, the detective voltage source could achieve the stable temperature coefficient of 29ppm/$^{\circ}C$ over the temperature range of -30$^{\circ}C$ to 70$^{\circ}C$. The current consumption of a voltage detector constituted by the proposed detective voltage source is $10{\mu}A$ from 1.9V-supply voltage at room temperature.

Extraction & Separation Behavior of Light Rare Earth Elements from the Mixed Solutions by Cyanex 572 (경희토류(La, Ce, Pr, Nd, Sm) 혼합용액에서 Cyanex 572에 의한 추출·분리 거동 고찰)

  • Cho, Yeon-Chul;Lee, Joo-Eun;So, Hong-Il;Ahn, Jae-Woo;Kim, Hong-In;Lee, Jin-Young
    • Resources Recycling
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    • v.26 no.4
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    • pp.79-87
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    • 2017
  • Extraction and separation behaviors of La, Ce, Pr, Nd and Sm from light rare earth multi - component mixed solutions by Cyanex 572 were studied. As extractant concentration increased, the $pH_{50}$ values of all the five components decreased. When extractant concentration was larger than 0.6 M, the separation factor of La and Ce, Nd and Sm was higher than 10, while the separation factor between Ce and Pr, Pr and Nd was as low as 0.5~2.2. Addition of TBP to the 0.6 M Cyanex 572 had little synergistic effect on the phase separation rate and separation factor. From the analysis of experiment results, group separation of [La]/[Pr, Nd, Sm] and [Pr, Nd]/[Sm] could be possible, but in case of the group separation between [La, Ce] and [Pr, Nd] was not available because of the low separation factor between Ce and Pr.

A Study on Injection Characteristics of High Temperature Fuel through Orifice Injectors (고온 연료의 오리피스 인젝터 분사특성 연구)

  • Lee, Hyung Ju;Choi, Hojin;Kim, Ildoo;Hwang, Ki-Young
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.42 no.2
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    • pp.119-126
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    • 2014
  • An experimental study was conducted to study fuel injection characteristics through plain orifice injectors when the fuel was heated to the temperature higher than its boiling point. Three injectors with different orifice diameters were used to measure the flow coefficient (${\alpha}$) for the injection pressure ranges of 3, 5, and 10 bar and the fuel temperature ranges between 50 and $270^{\circ}C$. The study showed that ${\alpha}$ decreases gradually with the fuel temperature below $180^{\circ}C$ while it drops abruptly when the temperature goes beyond $187^{\circ}C$, the boiling temperature of the fuel. The slope of ${\alpha}$ bifurcated at the boiling temperature for different injection pressures, and ${\alpha}$ decreased faster for the lower injection pressure due to the more active boiling in the injector. In addition, the larger orifice diameter had the higher ${\alpha}$ value, and ${\alpha}$ jumped at moderate temperature ranges when the injection pressure was low, implying the turbulent-laminar transition phenomena. The measured ${\alpha}$ was plotted against the cavitation number($K_c$), and the characteristics were independent of the applied pressure for small injectors when the fuel was evaporated before it was injected.

Laboratory Validation of Bridge Finite Model Updating Approach By Static Load Input/Deflection Output Measurements (정적하중입력/변위출력관계를 이용한 단경간 교량의 유한요소모델개선기법: 실내실험검증)

  • Kim, Sehoon;Koo, Ki Young;Lee, Jong-Jae
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.20 no.3
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    • pp.10-17
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    • 2016
  • This paper presents a laboratory validation of a new approach for Finite Element Model Updating(FEMU) on short-span bridges by combining ambient vibration measurements with static load input-deflection output measurements. The conventional FEMU approach based on modal parameters requires the assumption on the system mass matrix for the eigen-value analysis. The proposed approach doesn't require the assumption and even provides a way to update the mass matrix. The proposed approach consists of two steps: 1) updating the stiffness matrix using the static input-deflection output measurements, and 2) updating the mass matrix using a few lower natural frequencies. For a validation of the proposed approach, Young's modulus of the laboratory model was updated by the proposed approach and compared with the value obtained from strain-stress tests in a Universal Testing Machine. Result of the conventional FEMU was also compared with the result of the proposed approach. It was found that proposed approach successfully estimated the Young's modulus and the mass density reasonably while the conventional FEMU showed a large error when used with higher-modes. In addition, the FE modeling error was discussed.