• Journal of Digital Convergence
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• v.12 no.12
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• pp.643-650
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• 2014

The purpose of this study is to research the effect of walking exercise with acaiberry ingestion for 8 weeks on inflammatory markers of middle age women. The participators were aging from 40 to 50 aging healthy women. The first group is classified to ingest acaiberry(AB), the second group is classified to walking exercise with acaiberry ingestion(WE+AB), and third group is classified to just walking exercise(WE). The program was doing walking exercise 3 times per week for 8 weeks. Acaiberry ingestion is after walking exercise for 8 weeks. The amount of the acaiberry is 5g acaiberry dilutes with 100mg water to inhale before breakfast and dinner to monitor CRP of each group before ingest acaiberry and 8 weeks later how to change CRP and cardiovascular disease. Consequently, all of three groups such as: acaiberry ingestion group, walking exercise with acaiberry ingestion group, and just walking exercise group, has positive effect with WBC(white blood cell), Albumin, ESR(erythrocyte sedimentation rate), CRP(C-reactive protein), but Albumin increases very small amount of gaze. Therefore, this study has no longer period time for research, and in the future there should be more concrete and various studies, such as adding more exercise of method, intensity, and measure of ingestion for supporting this study.

• Journal of Life Science
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• v.25 no.8
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• pp.932-935
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• 2015

The purpose of this study was the effect of complex training of obese men in their 30s on inflammatory markers and homocysteine, a risk factor for cardiovascular disease. The subjects consisted of obese men (n=12) with the body fat ratio of 25% or above in their mid 30s who had no medical conditions and can follow the exercise routine required by this study. To achieve the purpose of this study measured the maximum oxygen intake (VO_2max) and 1RM of 5 kinds of machine(bench press, lat pull down, arm curl, leg press, squat) as a preliminary test; based on the results, performed 8 weeks complex training (aerobic exercise + weight training); and then analyzed the variation in body composition (body weight, body fat and BMI), blood inflammatory markers (IL-6, TNF-α and CRP), and homocysteine between before and after training. The results exhibited that 8 weeks complex training reduced weight, body fat and BMI significantly (p<0.01) and also reduced inflammatory marker CRP and homocysteine, a risk factor for cardiovascular disease, significantly (p<0.05). In conclusion, 8 weeks complex training confirmed the variation in body composition, and this variation has a positive effect on the inflammatory marker and the risk factor for cardiovascular disease.

• Journal of the Korea Society of Computer and Information
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• v.27 no.8
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• pp.185-194
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• 2022

The purpose of this study was to verify the effects of long-distance horseback riding on blood lipid, adipokines and inflammatory markers in obese middle-aged women. The subjects of this study were 9 obese meddle aged women and the data analysed using the paired t-test. The result of this study were as follows: First, TC(p<.01), LDL-C(p<.01), and HDL-C(p<.001) were significantly increased after long-distance horseback riding(LDHR). Second, adiponectin was significantly increased(p<.01) and also PAI-1 was significantly decreased(p<.01) after LDHR. Third, IL-6 was significantly increased(p<.01) after LDHR. These results suggest that long-distance horseback riding has positive effect on changes blood lipid, adipokines, and inflammatory markers in obese middle-aged women. Therefore we consider that effects of long-distance horseback riding has partial examine on prevention and therapy of obesity in middle-aged obese women who undergo physical and emotional big changed.

• Journal of Industrial Convergence
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• v.21 no.12
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• pp.75-81
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• 2023

This study was conducted to verify the effectiveness of a combined exercise program to improve the health of the elderly. For this purpose, 10 people in the exercise group and 10 in the control group were selected among seniors aged 65 years or older. The subject of this study was a 12-week combined exercise program in which aerobic and anaerobic exercise were performed three times a week for 60 minutes. Before participating in exercise, blood lipid and inflammatory index tests were conducted, and blood lipid and inflammatory index tests were conducted upon completion of the combined exercise program. The test results were verified with basic statistics and treatment effects between groups using the SPSS statistical program. Based on this, the following conclusions were obtained. First, the combined exercise program for elderly health promotion showed significant differences in TC, LDL, and TG in blood lipids between the exercise group and the control group, and there was an interaction effect on the treatment program. Second, the combined exercise program for improving the health of the elderly showed significant differences in inflammatory indicators IL-6 and TNF-a between the exercise group and the control group, and there was an interaction effect with the treatment program.

• Journal of dental hygiene science
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• v.12 no.1
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• pp.71-77
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• 2012

Sex Hormones exert significant influence in body physiology throughout life. Some reports suggested increased sex hormone levels correlate with an increased prevalence of gingivitis. The objectives of this pilot study are to(1) address the link between menstrual cycle and MMP-9, MMP-8, IL-$1{\beta}$ of gingival crevicular fluid during 4 weeks and (2) discuss the major biomarker of periodontal status. 7 female and 3 male volunteer who didn't have smoking habit, medical and dental disease after informed consent, were seen twice a week for 4 weeks. GCF samples were collected and GCF levels of MMP-9, MMP-8, IL-$1{\beta}$ were measured by enzyme-linked immunosorbent assay. The GCF levels of MMP-9, MMP-8, IL-$1{\beta}$ had fluctuation according to menstrual cycle, but the changes of those were not significant by Friedman matched samples test. There is no difference between female and male subjects by Mann-Whitney U test. The correlation of MMP-8, MMP-9 and IL-$1{\beta}$ showed strong by Spearman correlation(0.644-0.945). This study confirms menstrual cycle doesn't influence the periodontium of healthy female subjects.

• Journal of Nutrition and Health
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• v.44 no.6
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• pp.481-487
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• 2011

Obesity not only reduces bone mineral density but also increases inflammatory markers. Therefore, we examined the change in inflammatory markers and morphological microstructure of the bones using a mouse model fed a high-fat diet. C57BL/6J 4-week-old male mice were divided into a control group (n = 6) and a experimental group (n = 6); the control group was provided with 10% Kcal fat diet, and the high-fat diet group was provided with 45% Kcal fat diet for 12 weeks using the free provision method. Blood was analyzed for inflammatory markers, and micro-computed tomography was used to measure the morphological microstructure of the femoral bone. The weight increases in the control group and high-fat diet group were $5.85{\pm}1.84g$ and $16.06{\pm}5.64g$, respectively (p < 0.01), glucose was $115.00{\pm}16.88mg/dL$ and $188.33{\pm}13.29mg/dL$ (p < 0.01), and triglycerides were $65.00{\pm}6.19mg/dL$ and $103.33{\pm}8.02mg/dL$ (p < 0.05) respectively. Leptin and interleukin (IL)-6 were significantly higher in the high-fat diet group than that in the control group (p < 0.01). As a result of a biochemical index analysis of bone metabolism, osteocalcin tended to be lower in the high-fat diet group, whereas CTx was significantly higher in the high-fat diet group compared to that in the control group (p < 0.01). The thickness of the bony trabecula was significantly narrower in the high-fat diet group than that in the control group (p < 0.05), and the gap in the bony trabecula was significantly wider in the high-fat diet group than that in the control group (p < 0.05). IL-6 and the gap in the bone trabecula, which was a morphological microstructure of the bones, showed a positive correlation (p < 0.05). Taken together, inducing obesity through a high-fat diet in mice during the growth phase caused a change in bone microstructure and was correlated with the inflammation index. Accordingly, restriction of excessive fat intake may be needed to suppress the inflammatory reactions and promote normal bone formation.

• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.169-175
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• 2021

Objectives : Delirium is a temporary brain dysfunction and systemic inflammation is important factor in its pathophysiology. Whether the neutrophil-lymphocyte ratio (NLR), one of the inflammatory markers, can be used as an inflammatory marker in delirium patients was investigated in comparison with C-reactive protein (CRP). Methods : We retrospectively reviewed the medical records of patients who were referred for consultation for delirium at hospital for one year. The NLR and CRP values at admission and delirium status were divided into the medical and the surgical treatment group, and the interaction between them was analyzed through repeated measures ANOVA. Results : NLR was maintained without significant difference before and after delirium in the medical treatment group and the surgical treatment group, but CRP decreased in the medical treatment group and increased in the surgical treatment group during delirium, showing a significant interaction. Conclusions : In delirium patients, the NLR remained constant, but the CRP differed according to the treatment group and the delirium state. This suggests the possibility that NLR could be used complementary to CRP as an inflammatory marker in delirium patients.

• 한국임상약학회:학술대회논문집
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• 2007.12a
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• pp.179-179
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• 2007

• 한국체육학회지인문사회과학편
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• v.51 no.4
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• pp.407-417
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• 2012

The purpose of the study was to determine the effects of pilates mat exercise on cardiovascular disease risk factors and inflammation markers in sarcopenic obesity elderly. All subjects were sarcopenic obesity(height for each of the arms, legs, appendicular muscle mass ratio of 1.16kg/m², 4.31kg/m², 5.21kg/m² under and % body fat is more than 30%) elderly performed the pilates mat exercise during 12-week for 60 minutes 3 times a weeks. All subjects of this study were examined the changes in cardiovascular disease risk factors(TC, TG, HDL-C, LDL-C, Glucose, Insulin) and inflammation markers(fibrinogen, adiponectin, leptin, CRP). The results of the study in the exercise group were as follows; The weight, % body fat, TC, TG, LDL-C, fibrinogen, CRP had significantly decreased and muscle mass, HDL-C, adiponectin had significantly increased. And also, pilates mat exercise can effective to improve sarcopenic obesity, and pilates mat exercises performed coy shrink obesity to cardiovascular disease and inflammatory response indicators of older women as old man's physical features of the deterioration of the prevention of obesity and muscle strength loss, causing the effective exercise method is meant to be.

• Proceedings of the Korean Society of Disaster Information Conference
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• 2022.10a
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• pp.143-144
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• 2022

본 연구에서는 엄격성 지수(Strigency Index)분석에 따른 OECD 가입국들의 코로나19 대응 정책 엄격성의 효과성을 분석하였다. 코로나바이러스감염증-19(이하, 코로나19)발생 이후 전 세계 대다수 국가들은 점진적 일상회복 단계로 접어들어 'with corona' 시대로 가고 있다. 코로나19의 완전 방역을 이루며 이전과 같은 일상으로 돌아가고 있지만, 또다시 대규모 감염병이 발생할 수 있다는 가능성을 가지고 있다. 그리하여 본 연구에서는 옥스퍼드 코로나바이러스 정부대응추적 프로젝트(OxCGRT)에서 제시된 21개 지표 중 OurWorldinData서 엄격성 지수 분석에 활용되는 9개 지표를 분석하여 정책의 엄격성을 분석하여 추후 발생하는 대규모 감염병에 효과적으로 대응하기 위한 기초 자료가 되고자 한다. 엄격성 지수 분석 결과, 9개 지표 중 6개 지표에서 정책의 도입한 시점부터 확진자가 감소하는 추세를 보이는 유사한 변화를 찾을 수 있었다. 하지만, 엄격성 지수 분석을 통해 국가 대응의 적절성·효과성을 입증하기에는 판단 기준이 0~4점 사이의 임의의 기준으로 분류되고 있었으며, 변수설정 또한 제시되어 있지 않아 대응 정책의 엄격성을 평가하는 기준으로 활용하기에는 한계점이 있어 보인다. 본 연구에서 엄격성 지수 분석을 통한 감염병 대응 정책의 효과성을 찾고자 하였다. 지수와 확진자 추세 간 유사한 변화는 찾았지만, 엄격성 지수의 한계점이 존재하는 연구이다. 그러나 본 연구의 결과를 통해 추후 확진자 증감 대비 엄격성 지수 분석을 통한 상관관계 분석, 지표별 평균치와 확진자 추세 분석을 통한 공통적인 효과성 분석 등 다른 연구의 기초 자료가 될 수 있을 것이라 판단된다.