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http://dx.doi.org/10.5352/JLS.2015.25.8.932

Effect of Complex Training on Inflammatory Markers and Homocysteine of Obese Men  

Jin, Chan-Ho (Department of Leisure and Gaming, Hanseo University)
Kwak, Yi-Sub (Department of Physical Education, Dong-Eui University)
Publication Information
Journal of Life Science / v.25, no.8, 2015 , pp. 932-935 More about this Journal
Abstract
The purpose of this study was the effect of complex training of obese men in their 30s on inflammatory markers and homocysteine, a risk factor for cardiovascular disease. The subjects consisted of obese men (n=12) with the body fat ratio of 25% or above in their mid 30s who had no medical conditions and can follow the exercise routine required by this study. To achieve the purpose of this study measured the maximum oxygen intake (VO2max) and 1RM of 5 kinds of machine(bench press, lat pull down, arm curl, leg press, squat) as a preliminary test; based on the results, performed 8 weeks complex training (aerobic exercise + weight training); and then analyzed the variation in body composition (body weight, body fat and BMI), blood inflammatory markers (IL-6, TNF-α and CRP), and homocysteine between before and after training. The results exhibited that 8 weeks complex training reduced weight, body fat and BMI significantly (p<0.01) and also reduced inflammatory marker CRP and homocysteine, a risk factor for cardiovascular disease, significantly (p<0.05). In conclusion, 8 weeks complex training confirmed the variation in body composition, and this variation has a positive effect on the inflammatory marker and the risk factor for cardiovascular disease.
Keywords
Complex training; homocysteine; inflammatory marker; obesity;
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1 Karvonen, M. J., Kentala, E. and Mustala, O. 1957. The effects of training on heart rate; a longitudinal study. Ann. Med. Exp. Biol. Fenn. 35, 307-315.
2 Paik, I. Y. 2009. Exercise and Energy Metabolism, 2nd ed., Yonsei University: Seoul, Korea.
3 Park, K. Y. and Kim, J. S. 2013. The effects of exercise modalities on the apolipoproten A-I, Apolipoprotein B and C-Reactive Protein in Obese High School Girls. Exer. Sci. 22, 309-317.   DOI
4 American College of Sports Medicine. 2006. ACSM’s guidelines for exercise testing and prescription, 7th ed., Lippincott Williams & Wilkins: Baltimore, USA.
5 Andersson, A., Brattstrom, L., Isaksson, A., Israelsson, B. and Hultberg, B. 1989. Determination of homocysteine in plasma by ion-exchange chromatography. Scand. J. Clin. Lab. Invest. 49, 445-449.   DOI
6 Brooks, G. A., Fahey, T. D. and Baldwin, K. M. 2005. Exercise Physiology: Human Bioenergetics and Its Applications, 4th ed., McGraw-Hill Higher Education: New York, USA.
7 Bruun, J. M., Helge, J. W., Richelsen, B. and Stallknecht, B. 2006. Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. Am. J. Physiol. Endocrinol. Metab. 290, E961-967.   DOI
8 Vieira, V. J., Valentine, R. J., Wilund, K. R., Antao, N., Baynard, T. and Woods, J. A. 2009. Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice. Am. J. Physiol. Endocrinol. Metab. 296, E1164-1171.   DOI
9 Vincent, H. K., Bourguignon, C. and Vincent, K. R. 2006. Resistance training lowers exercise-induced oxidative stress and homocysteine levels in overweight and obese older adults. Obesity (Silver Spring) 14, 1921-1930.   DOI
10 Pasceri, V., Cheng, J. S., Willerson, J. T. and Yeh, E. T. 2001. Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs. Circulation 103, 2531-2534.   DOI
11 Pedersen, B. K. 2006. The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control. Essays Biochem. 42, 105-117.   DOI
12 Poulos, S. P., Hausman, D. B. and Hausman, G. J. 2010. The development and endocrine functions of adipose tissue. Mol. Cell. Endocrinol. 323, 20-34.   DOI
13 Reeder, S. J., Hoffmann, R. L., Magdic, K. S. and Rodgers, J. M. 2000. Homocysteine: the latest risk factor for heart disease. Dimens. Crit. Care Nurs. 19, 22-28.
14 Ridker, P. M., Rifai, N., Rose, L., Buring, J. E. and Cook, N. R. 2002. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N. Engl. J. Med. 347, 1557-1565.   DOI
15 Shim, S. Y., Kim, Y. M. and Ko, S. K. 2011. The effects of pilates on body composition, cholesterol, CRP and leptin in male obese adults. Kor. J. Sports Science 20, 1301-1312.
16 Duncan, G. E., Perri, M. G., Anton, S. D., Limacher, M. C., Martin, A. D., Lowenthal, D. T., Arning, E., Bottiglieri, T. and Stacpoole, P. W. 2004. Effects of exercise on emerging and traditional cardiovascular risk factors. Prev. Med. 39, 894-902.   DOI
17 Shoelson, S. E., Herrero, L. and Naaz, A. 2007. Obesity, inflammation, and insulin resistance. Gastroenterology 132, 2169-2180.   DOI
18 The Korean Nutrtion Society. 2010. Dietary reference intakes for Koreans 2010, The Korean Nutrtion Society: Seoul, Korea.
19 Ueland, P. M., Refsum, H., Stabler, S. P., Malinow, M. R., Andersson, A. and Allen, R. H. 1993. Total homocysteine in plasma or serum: methods and clinical applications. Clin. Chem. 39, 1764-1779.
20 Gallistl, S., Sudi, K. M., Cvirn, G., Muntean, W. and Borkenstein, M. 2001. Effects of short-term energy restriction and physical training on haemostatic risk factors for coronary heart disease in obese children and adolescents. Int. J. Obes. Relat. Metab. Disord. 25, 529-532.   DOI
21 Gaume, V., Mougin, F., Figard, H., Simon-Rigaud, M. L., N'Guyen, U. N., Callier, J., Kantelip, J. P. and Berthelot, A. 2005. Physical training decreases total plasma homocysteine and cysteine in middle-aged subjects. Ann. Nutr. Metab. 49, 125-131.   DOI
22 Gelecek, N., Teoman, N., Ozdirenc, M., Pinar, L., Akan, P., Bediz, C. and Kozan, O. 2007. Influences of acute and chronic aerobic exercise on the plasma homocysteine level. Ann. Nutr. Metab. 51, 53-58.   DOI
23 Huang, C. J., Zourdos, M. C., Jo, E. and Ormsbee, M. J. 2013. Influence of physical activity and nutrition on obesity-related immune function. ScientificWorldJournal 2013, 752071.