• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.13 no.2
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• pp.172-179
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• 2010

Purpose: Visceral adipose tissue may be strongly linked to increased metabolic risks in adults. However, because little is known regarding the effect of visceral adipose tissue in children and adolescents, we performed this study to determine the association between abdominal fat distribution and metabolic risk factors in this population. Methods: One hundred one children and adolescents (78 males and 23 females; mean age, 10.8${\pm}$2.4 years) were enrolled. The anthropometric data and metabolic risk factors were evaluated. Theabdominal fat distribution was assessed according to the CT measurement. Age-adjusted, partial correlations were performed among the visceral adipose fat area (VFA), subcutaneous adiposefat area (SFA), metabolic risk factors, and anthropometrics. Results: The SFA increased more rapidly than the VFA with advancing years in both genders. In males, the VFA and SFA were positively correlated with anthropometrics. The VFA was correlated with low HDL-cholesterol and the SFA was correlated with diastolic blood pressure (DBP). However, there was no statistical significance between the VFA, SFA, anthropometrics, and other metabolic risk factors. The VFA and SFA were strongly linked to a number of metabolic risk factors, such as other anthropometrics. Conclusion: This study investigated how a low HDL-C was correlated with VFA and how a high DBP was associated with SFA in Korean male children and adolescents. Our results suggest that the correlation between the VFA, SFA, and metabolic risk factors was relatively weak compared to that reported in previous adult studies.

• Tuberculosis and Respiratory Diseases
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• v.59 no.1
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• pp.62-68
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• 2005

Background : The clinical results of a Natural stent in patients with a benign tracheobronchial stenosis were examined by comparing the clinical outcomes and complications of those patients who underwent Dumon and Natural stenting in the management of benign airway stenosis. Methods : The medical records of 94 patients (39 Dumon and 55 Natural stent) with a benign tracheobronchial stenosis were reviewed and analyzed. Results : Post-tuberculous stenosis was the leading indication for airway stenting (74%), which was followed by post-intubation stenosis (21%). After intervention, the dyspnea had improved among those patients who underwent Dumon (90%) and Natural (86%) stenting. After stabilizing the dyspnea, the stent could be successfully removed in half of the patients who underwent both Dumon (54%) and Natural (49%) stenting. During the 42 month follow-up period, the complication rate was similar in those patients who underwent Dumon and Natural stenting: migration (46% vs 53%), granulation tissue formation (36% vs 49%), mucostasis (21% vs 16%) and restenosis (51% vs 36%). Conclusion : The clinical results of Natural airway stent was similar to those of Dumon stent in the management of benign tracheobronchial stenosis.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.1
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• pp.121-124
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• 2009

This study was conducted to investigate the reason for the increase in the antioxidant activity of cooking drip from Enteroctopus dofleini by gamma and electron-beam irradiation. To define the effect of irradiation on the antioxidant activity of polyphenol in cooking drip, polyphenol excluded cooking drip extracts were prepared with polyclar$^{TM}$. But, the antioxidant activity of the cooking drip extracts without polyphenol was still increased by both irradiations. Instead, the effect on the proteins in the cooking drips prepared by ammonium sulfate precipitation showed great increase in antioxidative activity by irradiation. From these results, it was concluded that the increase in the antioxidative activity in cooking drips by the irradiation was caused by the structural modification of proteins in the cooking drips.

• Tuberculosis and Respiratory Diseases
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• v.66 no.3
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• pp.186-191
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• 2009

Background: Osteoporosis is a significant comorbidity in patients with chronic obstructive pulmonary disease (COPD). This study examined the prevalence and risk factors associated with osteoporosis in patients with COPD. Methods: The bone mineral densities (BMDs) of the lumbar spine and femoral bone were measured in 53 patients with clinically stable COPD and 41 age- and gender-matched control subjects showing a normal lung function. Osteoporosis was defined as a T-score $\leq$-2.5. The subjects' clinical characteristics and laboratory data were reviewed, and multiple logistic regression analysis was used to identify the risk factors associated with osteoporosis in COPD patients. Results: The prevalence of osteoporosis was 47% and 32% in the COPD patients and controls, respectively. In particular, using the femoral neck T-score, the prevalence of osteoporosis in COPD patients was higher than that in the controls (26% vs. 5%; p=0.006). The average T-score of the lumbar spine (p=0.025) and femoral neck of COPD patients were significantly lower than those of the controls (p=0.001). The forced expiratory volume in the 1 second ($FEV_1$) % predicted (p=0.019; odds ratio [OR], 0.955; 95% confidence interval [CI], 0.919-0.993) and age (p=0.024; OR, 1.144; 95% CI, 1.018-1.287) were independently associated with osteoporosis in patients with COPD. Conclusion: Using the femoral neck T-score, the prevalence of osteoporosis in patients with COPD was higher than the age-and gender-matched controls. A lower $FEV_1$ and older age further increase the risk of osteoporosis in patients with COPD.

• Journal of the Korean earth science society
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• v.22 no.1
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• pp.40-46
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• 2001

Heat exchange between the atmosphere and sea is produced using the data from two 3m discus buoy installed by KMA in 1996. The meteorological and oceanic characteristics at the Dukjukdo and Chilbaldo buoy for the period 1996 ${\sim}$ 2000 are discussed. Daily averaged sensible heat and latent heat flux at each site are estimated from bulk aerodynamic method using given data and analyzed. Quantitative analyses show SST indicates 1-year cycle like air temperature but has 1 month lag. Sea level pressure is lowest in July, humidity is higher from May to August, and wind speed has averaged value of 5 m/s and higher in autumn and winter. Sensible heat flux analyses present that strong heat loss from the sea occurs in autumn and winter and weak heat loss from atmosphere appears in spring and summer, and net sensible heat loss from the sea is found throughout the year. The ocean significantly releases latent heat into atmosphere from August to May but get a little latent heat from atmosphere in other months. Net latent heat loss from the sea is larger than net sensible heat loss except in January and February. Comparison with two sites suggests that the magnitude of heat flux and their fluctuation are generally stronger at Dukjukdo than at Chilbaldo. In case study, both sensible and latent heat flux is a little more at Chilbaldo in March 1998, but substantially stronger at Dukjukdo in November 1996.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.233-236
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• 2001

일반적으로 스피커를 동작시키게 되면, 스피커 보이스 코일에 열이 발생하게 되고, 열에 의한 보이스코일의 저항의 증가가 나타나게 되는데, 기존의 연구는 저음용 스피커(Woofer) 만을 대상으로 스피커의 음향특성 변화들에 관해 수행되었다. 그러나, 현대의 스피커는 A/V시스템분야의 발전에 따라 고음재생의 충실도가 강조되고 있는 경향이므로, 고음용 스피커(Tweeter)에 대한 열 발생의 영향을 조사하였다. 본 연구에서는 고음용 스피커의 입력전력에 따른 특성 변화를 조사하고, 입력전력의 증가로 인한 보이스코일(voice coil)의 저항 증가에 따른 고음용 스피커의 특성변화에 관해 실험하였다. 그리고, 스피커의 진동에 의한 펌프(pump) 역할을 이용하는 냉각용 구멍을 뚫어 스피커의 특성변화를 검토하였다. 실험대상으로는 직경 25mm의 돔(Dome)형 진동판을 가진 고음용 스피커와 이 스피커의 후면 중심부에 구멍을 뚫어 열 방출구가 형성된 3종의 시료를 대상으로 특성변화를 비교$\cdot$측정하였다. 여기에서, 사용된 시료는 국내 Y사의 판매용 고음용 스피커로 제품의 원 상태인, 구멍이 없는 것을 기준시료로 하고, 이와 동일한 제품들의 후면에 각각 직경 5mm, 10mm, 15mm의 구멍을 가공하여 비교시료로 하였다. 기준 및 비교시료의 스피커 특성을, 한국산업규격 KS C 6027의 측정법에 따라, 입력 1W 상태에서 기준시료의 사양을 측정하였고[1], 입력을 0.5W, 1W, 2W, 4W, 8W, 16W로 가하여, 시료별 입력증가에 따른 스피커의 주파수 응답특성, 임피던스(Impedance), 조화 왜(Harmonic Distortion)의 변화율 측정을 통해 스피커의 특성변화 정도를 검토하였다. 향후, 본 연구의 결과는 고음용 스피커의 특성 열화에 대한 예측 및 개선 방안을 제시하는 기본 자료로 활용이 가능할 것으로 사료된다.용하여 현금흐름예측을 할 수 있는 Model을 제시하였다. 특히 건설공사의 현금흐름 예측의 중요한 요소인 Cash-Out에 대하여, 공사비 구성요소인 자재, 노무, 중기, 외주, 경비등 각 Resource의 보할(Weights)을 실 공사원가에 따른 보할의 변화와 Resource들의 Time Lag를 적용 기존 연구자의 Model과 다른 Model을 제시하였다. 또한 기존 연구자들의 Model과 비교하여 편리성, 정확도 및 신뢰성이 높은 Model임도 증명하였다.세대까지도 발현수준이 유지될 것으로 판단된다. 이러한 연구결과는 계통으로 확립된 형질전환 동물에 부여된 새로운 유전형질은 지속적으로 후대로 유전될 수 있음을 제시한다.잖⨀瘀Ā퀇Āゑ잖⨀Ā퀇Ԁ￿™잖⨀䌀Ā퀇ĀꄏĀꀏꄏĀꀏ₱?⨀Ā Ԁ￿䂱?⨀ऀĀ耀Ā삱?⨀؀Ā Ā?⨀ጀĀ耀Ā?돀ꢘ?⨀硩?⨀ႎ?⨀?⨀넆돐쁖잖⨀쁖잖⨀／ࠐ?⨀焆덐瀆倆Āⶇ퍟ⶇ퍟ĀĀĀĀ磀鲕좗?⨀肤?⨀⁅Ⴅ?⨀쀃잖⨀䣙熸ጁ↏?⨀

• Journal of Korea Water Resources Association
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• v.49 no.8
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• pp.685-692
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• 2016

This study aimed to develop the indicator-based approach to assess water use vulnerability in watersheds and applied to the unit watershed within the Han River watershed. Vulnerability indices were comprised of three sub-components (exposure, sensitivity, adaptive capacity) with respect to water use. The indicators were made up of 16 water use indicators. Then we estimated vulnerability indices using the Technique for Order of Preference by Similarity to Ideal Solution approach (TOPSIS). We collected environmental and socio-economic data from national statistics database, and used them for simulated results by the Soil and Water Assessment Tool (SWAT) model. For estimating the weighted values for each indicator, expert surveys for subjective weight and data-based Shannon's entropy method for objective weight were utilized. With comparing the vulnerability ranks and analyzing rank correlation between two methods, we evaluated the vulnerabilities for the Han River watershed. For water use, vulnerable watersheds showed high water use and the water leakage ratio. The indices from both weighting methods showed similar spatial distribution in general. Such results suggests that the approach to consider different weighting methods would be important for reliably assessing the water use vulnerability in watersheds.

• Journal of Conservation Science
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• v.37 no.5
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• pp.536-544
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• 2021

In the present study, safe management and value improvement of bamboo sunblind, which is an item of cultural heritage, were performed by adopting stable conservation treatment methods. The bamboo sunblind used in the present study was excavated from No. 1 catchment site in Baesanseongji, Busan. It was determined that the main material used to make the sunblind was bamboo, and herbal plants were used to weave the bamboo using lacquer as an adhesive agent. All contaminants and soil adhered to the sunblind was removed. Thereafter, the sunblind, which was recovered in the form of blocks, was washed separately after fixing it to a temporary plaster frame and to avoid the blocks from breaking during washing. Then, polyethylene glycol (PEG) impregnation was utilized for the reinforcement treatment. Based on the preliminary test results, the shape of the sunblind was fixed using a stainless-steel frame to prevent physical damage that may occur during the drying process. Thereafter, the bamboo sunblind was vacuum freeze-dried. PEG 20% (in ethyl alcohol) was applied as a surface treatment agent for stabilization the sunblind. After the surface treatment, the bamboo sunblind were joined together to fit the maximum width, and the rectangular shape of the sunblind was restored-as best as possible-while filling in the missing parts by maximizing the use of unknown members such as in the disturbed layers below bamboo sunblind surface. The conservation treatment was completed by fixing the bamboo sunblind into the fabricated frame.

• Journal of Environmental Impact Assessment
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• v.32 no.5
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• pp.338-352
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• 2023

As of 2019, Korea's fine dust is the most severe among 38 OECD countries, and in the same year, 「the Framework on Disaster and Safety Management」 was revised to define fine dust as a social disaster. Currently, the government is working to achieve its emission reduction goals by preparing a comprehensive fine dust management plan (2022-2023) consisting of a total of five areas, 42 tasks, and 177 detailed tasks. However, it is necessary to come up with measures in consideration of the various spatial characteristics of the city, not just as a source of emission. Therefore, in this study, the shape of the city was classified using the LCZ (Local Climate Zone) classification system into 17 types by building type and land cover type in Busan, and the average annual PM10 and PM2.5 concentration were mapped using the IDW technique. In addition, Fragstats and Moving Window were used to quantify the LCZ classification system. Finally, correlation analysis and regression analysis were conducted to analyze the relationship between the LCZ classification system and PM10 and PM2.5. As a result, it was confirmed that the type of low height of the building and the type of green space with trees had a positive effect on the concentration of PM10 and PM2.5. Therefore, this study is expected to be used as basic data to establish fine dust reduction policies based on efficient spatial planning.

• Tuberculosis and Respiratory Diseases
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• v.66 no.4
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• pp.280-287
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• 2009

Background: The epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), became an attractive therapeutic option for advanced non-small-cell lung cancer (NSCLC). Several studies suggested that there might be some different efficacy or response predictors between gefitinib and erlotinib. We compared the efficacy and toxicity of gefitinib and erlotinib in Korean patients with advanced NSCLC and evaluated specific predictors of response for both gefitinib and erlotinib. Methods: We collected the clinical information on patients with advanced NSCLC, who were treated with gefitinib or erlotinib at the Ewha Womans University Hospital, between July 2003 and February 2009. Median survival times were calculated using the Kaplan-Meier method. Results: Eighty-six patients (52 gefitinib vs. 34 erlotinib) were enrolled. Patient median age was 64 years; 53 (62%) subjects were male. Out of the 86 patients treated, 83 received response evaluation. Of the 83 patients, 35 achieved a response and 12 experienced stable disease while 36 experienced progressive disease, resulting in a response rate of 42% and a disease control rate of 57%. After a median follow-up of 502 days, the median progression-free and overall survival time was 129 and 259 days, respectively. Comparing patients by treatment (gefitinib vs erlotinib), there were no significant differences in the overall response rate (44% vs. 39%, p=0.678), median survival time (301 days vs. 202 days, p=0.151), or time to progression (136 days vs. 92 days, p=0.672). Both EGFR-TKIs showed similar toxicity. In a multivariate analysis using Cox regression model, adenocarcinoma was an independent predictor of survival (p=0.006; hazard ratio [HR], 0.487; 95% confidence interval [CI], 0.292-0.811). Analyses of subgroups did not show any difference in response predictors between gefitinib and erlotinib. Conclusion: Comparing gefitinib to erlotinib, there were no differences in the response rate, overall survival, progression-free survival, or toxicity. No specific predictor of response to each EGFR-TKI was identified.