• The Journal of the Korean bone and joint tumor society
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• 제18권1호
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• pp.20-27
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• 2012

Purpose: The chemokine receptor CXCR4 has been reported to be aberrantly expressed in human cancer and has been shown to participate in cancer metastasis. We compared the expression of CXCR4 in conventional high-grade and low-grade central osteosarcomas, and determined if an association between CXCR4 expression and prognosis could be made. Materials and Methods: We performed the immunohistochemistry for CXCR4 in a total of 63 patients with osteosarcoma and determined the relationships according to the clinicopathologic variables and overall survival rates. Results: CXCR4 was detected in 76.3% of conventional high-grade osteosarcoma patients and in 36% of low-grade central osteosarcomas. Diffuse expression was noted in 47.4% of the high-grade osteosarcomas and all low-grade cases were focal positive. CXCR4 expression was significantly correlated with histologic grade (p<0.0001). While overall survival rate was reduced significantly with increased CXCR4 expression (p=0.0058), higher histologic grade (p<0.0001), and younger age (p=0.0140), survival rate did not correlate with gender, tumor size, or AJCC stage. Conclusion: Our results suggest that CXCR4 expression is associated with higher-grade tumors and with poor prognosis for osteosarcoma patients.

• Journal of the Korean Society of Radiology
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• 제13권3호
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• pp.349-357
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• 2019

The purpose of this study was to evaluate the clinical significance of ultrasonographic classification of fatty liver in three grades. From June 2018 to April 2019, 1047 patients (818 males and 229 females) diagnosed as fatty liver among 3607 patients who underwent abdominal ultrasonography at Busan screening center. Ultrasonography was classified into three grades: Grade I (mild fatty liver), Grade II (moderate fatty liver), and Grade III (severe fatty liver) according to the degree of parenchyma texture, acoustic attenuation, Obesity index, hematological test, and metabolic syndrome. The average age of men in each sex increased with the increase of the fatty liver. Body mass index (BMI) and waist circumference were significantly increased in both men and women (p=.000). hematological analysis showed that AST, ALT, ${\gamma}-GTP$, TG, fasting blood sugar, and glycated hemoglobin were significantly different from each other (p<.05). In women, ALT, ${\gamma}-GTP$ and TG showed a significant difference with increasing fatty liver (p<.05). The prevalence of metabolic syndrome was significantly increased in both sexes as the grade of fatty liver increased (p=.000). Based on the results of this study, it is suggested that the use of ultrasound - guided fatty liver according to severity may be useful for the treatment and follow - up of fatty liver if the liver grade is divided in consideration of hematological variables and metabolic syndrome.

• Proceedings of the Korea Multimedia Society Conference
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• 한국멀티미디어학회 2002년도 추계학술발표논문집
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• pp.275-278
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• 2002

우리는 정보를 찾기 위해서 신문, 도서관보다는 인터넷을 먼저 검색한다. 이와 같은 사회환경에서 불건전 정보 증가는 이전 사회에서 인식하지 못했던 문제를 야기하고 있다. 그 대상이 청소년뿐만 아니라 아동까지 확대되고 있어, 문제는 더욱 더 커질 수 있다. 이러한 문제점을 극복하기 위해 본 논문에서는 연령별 또는 등급별 웹브라우저를 통하여 접근할 수 있는 범위를 제한하여 전문 검색 에이전트를 통하여 검색과 카테고리 분류를 하여 DB구축을 제안하고, 네트워크의 데이터링크 계층에 속하는 NIC(Network Interface Card)의 드라이버 수준에서 건전 사이트만을 접근이 가능하도록 폐쇄형 브라우저 시스템의 설계 및 구현방법에 대해서 논의한다.

• The Bulletin of The Korean Astronomical Society
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• 제37권2호
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• pp.147.2-147.2
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• 2012

보현산 천문대 1.8m 망원경과 2K CCD를 이용하여 늙은 산개성단 NGC 2420에 대해 V ~ 22까지 VI측광 관측을 수행하였다. Chi^2 최소화를 이용한 정밀한 이론적인 등연령 곡선 맞추기 방법으로 성단의 기본 물리량을 구하고, 색-등급도(CMD)와 공간상에서의 별들의 위치를 이용하여 별들의 통계적인 구성원 확률을 결정하고자 한다. 한편 쌍성의 공간상의 분포를 조사하여 역학적 진화에 따른 쌍성의 분포특징을 살펴보고, 2차원 표면개수 밀도 분포로부터 성단의 형태를 조사하여 우리 은하면과의 상관관계에 대해 논의하고자 한다.

• The Bulletin of The Korean Astronomical Society
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• 제36권1호
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• pp.32-32
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• 2011

파묻힌 성단 NGC1333은 광학영역에서는 성운이 별을 가리고 있어서 관측 연구가 힘든 천체이다. 이 연구에서는 광학영역이 아닌 근적외선영역의 관측 자료를 이용하여 NGC1333 내 전주계열(pre-main sequence) 변광성을 찾아내었다. 관측 자료는 2005년11월부터 2007년 10월까지 미국 버지니아대학 Fan mountain 관측소의 31인치 반사망원경에 부착된 근적외선 카메라 Fancam에서 얻어졌다. Stetson 변광 지수(Stetson, 1996)를 이용해 변광 여부를 정하였다. 별 탄생 지역에서의 등연령곡선 모형을 적용한 색-등급도를 그리고 등연령곡선과 소광 현상 보정을 이용해 각 별들의 질량을 추정하였다.

• The Korean Journal of Nuclear Medicine
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• 제33권6호
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• pp.484-492
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• 1999

Purpose: This study was to evaluate the clinical usefulness of $^{99m}Tc$-MDP bone scintigraphy for assessing vascular ingrowth into the ocular implants after enucleation or evisceration. Materials and Methods: Twenty-four patients (M:F=7:17, mean age: 36 years), who buried a coralline hydroxyapatite after uncomplicated enucleation or evisceration surgery were studied. Dynamic and static scintigraphy on the orbit fossa were obtained after injection of 740 MBq $^{99m}Tc$-MDP to evaluate the status of vascularization. The study was performed from the 3 to 33 weeks after surgery. According to the visual analysis, activity greater than nasal bridge was graded as 4, equal to the nasal bridge as 3, less than nasal bridge but greater than normal orbit as 2, greater than normal orbit but less than grade 2 as 1. Uptake ratio was also calculated by measuring the implants activity (H) and contralateral orbit activity (N). Grading score and uptake ratio were compared with clinical outcome of vascularization. Additionally, we also analyzed the vascularization status as time lapse between primary surgery and scintigraphic study and surgical methods. Results: Twenty-one patients who had bone scintigraphy at 11 weeks after surgery showed increased uptake above grade 2 and greater H/N ratio than 1.16. Of these, 19 patients who had drilling surgery for permanent peg application showed adequate bleeding during the procedure. The activity grade and uptake ratio were inversely correlated with vascular ingrowth. Higher than grade 2 or greater than 1.56 in H/N ratio seemed to be an indicator for better prognosis. Accomplishment of vascularization was not affected by the surgical way such as enucleation or evisceration. Conclusion: $^{99m}Tc$-MDP bone scintigraphy can be a useful method to evaluate the vascularized status of implants. Adequate time for $^{99m}Tc$-MDP bone scintigraphy may be 11-20 weeks after enucleation or evisceration.

• Current Research on Agriculture and Life Sciences
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• 제32권4호
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• pp.225-230
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• 2014

This study investigates the effect of organic certification of apples on consumer preference in China as a way to support the expanded export of Korean apples to China. A choice experiment was designed to analyze the apple consumption in China. A total of 298 Chinese consumers answered the survey, and multinomial logit models were used to analyze the results. Organic certification was identified as an important determinant of consumer preference for apples in China, affecting both the evaluation and choice of country of origin. The results also indicated that Korean organic certification significantly increased the probability of Chinese consumers choosing Korean apples. Thus, organic certification by the Korean government should be strengthened to promote apple exports to China, plus the results of this study may provide useful information to promote agricultural product exports and improve the organic certification system.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제18권5호
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• pp.219-225
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• 2017

This article examined the condition of medical service utilization and the usage degree for the disabled in Korea, and analyzed factors affecting medical service utilization. This paper offers data for improving the health of disabled Korea residents and for enhancing medical service utilization. We analyzed data for disabled residents aged 19 from the 6th Korea National Health and Nutrition Examination Survey. Results found significant effects depending on gender, age, average monthly income, types of disorders, disability rating, and status of smoking. Concerning gender, men had a higher probability of lacking medical treatment compared with women, had increased probability of having a disability, and smokers had a higher probability of lacking treatment compared with nonsmokers. Therefore, for resolving medically untreated disabled Korean residents, government needs to improve the policy system and to managethe inequality of handicapped welfare work.

• Food Science of Animal Resources
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• 제30권2호
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• pp.321-327
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• 2010

The effect of cattle sex (cow, bull, and steer) on carcass traits of quality grade factors, physicochemical, and sensory traits of Longissimus Dorsi in Hanwoo was evaluated. Carcass traits of 42,113 heads were collected nation-wide and 257 heads were slaughtered to analyze beef quality. Sex affected significantly marbling score, meat color, fat color, texture, maturity, and quality grade of Hanwoo (p<0.05). Hanwoo steer carcasses had the highest marbling score (5.02), maturity (2.17), and texture (1.31) than those of cows and heifers. Crude fat of steers was higher than that of other cows and bulls. Steers showed the highest $L^*$(39.01), Warner-Bratzler shear force (4.03 kg), and water holding capacity (57.08%), however, there was no significant differences between those of cows and bulls. Ultimate$pH_{24}$ was shown difference among sex (5.58-5.69), however, the values remained within normal range. In sensory evaluation analyses, sex affected significantly tenderness, juiciness, and flavor (p<0.05). Also, the over all acceptability of steer beef was significantly higher than that of cow and bull beef. These results could be used as fundamental data set for further research activities to elevate Hanwoo beef qualities (p<0.05).

• Journal of the Korean Society of Radiology
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• 제83권1호
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• pp.102-111
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• 2022

Purpose To evaluate the correlation between Lee's grades and surgical intervention for central lumbar spinal stenosis (CLSS) and to assess whether this grading system can be used as a decision-making tool for the surgical treatment of this condition. Materials and Methods This retrospective study included 290 patients (M:F = 156:134; mean age, 46 ± 16 years). Radiologists assessed the presence and grade of CLSS at the stenosis point according to Lee's grading system, in which CLSS is classified into four grades according to the shape of the cauda equina. Correlation coefficients (r_s) between Lee's grades and the operation were calculated with Spearman rank correlation. Results Among the operated patients, grade 2 was the most commonly assigned grade (50%-58%), grade 3 was less common (35%), and grade 0 was the least common (2%-3%). Among the non-operated patients, grade 1 was the most common (63%-65%), grade 0 was less common (15%-16%), and grade 3 was the least common (8%). The distribution of grades differed between the operated and non-operated groups (p < 0.001). Less than 25% of patients who underwent surgery were assigned grades 0 and 1, and more than 88% were assigned grades 2 and 3. A moderate correlation was found between the grade and surgical intervention (r_s = 0.632 and r_s = 0.583). Conclusion Lee's grade was moderately correlated with surgical intervention. Lee's grading system can be a decision-making tool for the surgical treatment of CLSS.