• Tuberculosis and Respiratory Diseases
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• v.63 no.4
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• pp.362-367
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• 2007

Hormonal replacement therapy (HRT) has been proven for treatment of postmenopausal symptoms such as hot flushes, night sweats and urologic symptoms. HRT became very popular in the 1990's, when there were several reports showing that it also helped with other menopausal complications such as osteoporosis and cardiovascular disease. Recent studies report that the incidence of breast cancer, endometrial cancer, cerebral infarction, coronary artery diseases, deep vein thrombosis and pulmonary thrombembolism could rise after HRT. Among these side effects of HRT, the risk of pulmonary thromboembolism increases 2 to 4 fold after HRT, but can vary with the use of different doses and preparations. Here, we summarize the risk factors and clinical courses for 5 patients who developed pulmonary thromboembolism after postmenopausal HRT.

• Korean Journal of Biological Psychiatry
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• v.3 no.1
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• pp.96-101
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• 1996

Objects : There has been the controversy that menopause may or may not influence the psychological distresses. The purpose of this study was to investigate the correlation between the hormonal status and traits of depression & anxiety in menopausal women. Method : Among the women attending menopausal clinic. menopausal women, defined as who having a amenorrhea for more than 12 months, were selected as a study group(n=83). The control group(n=73), who visited to screen the cervix cancer with regular menstruation, hod no history of hormone replacement therapy. Individual data were collected by self-reporting questionnaires. Depression state was evaluated by Beck Depression Inventory(BDI) and anxiety state by Stale Trail Anxiety Inventory(STAI), and the female hormones such as E2, FSH, and LH were obtained by blood sampling at visting clinic. Statistically the data were processed by t-test and pearson correlation analysis(p<0.05). Results : 1) The mean age of menopausal was 45.3 years. 2) In menopausal women the scores of BDI & STAI were significantly higher than in control group(p<0.05). 3) There were significant differences between menopausal and control group by E2 & FSH. 4) There was no correlation between female hormonal status and the STAI & BDI scores in both groups. Conclusion : Although menopausal women had more traits of depression & anxiety than control group, it was difficult to insist that the lack of estrogen was the only etiological factor for the traits of depression & anxiety in menopausal period. In further studies, we must consider another factors, including biological, sociocultural, psychological factor, as the cause of psychological symptoms during menopausal period.

• 건강소식
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• v.30 no.12 s.337
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• pp.6-11
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• 2006

남성도 갱년기를 겪는다. 중년 여성의 전유물로 여겨졌던 갱년기가 남성에게도 나타나는 것이다. 40세 이후 남성의 신체기능 저하는 최근까지 자연적인 노화현상으로 치부됐다. 그러나 평균수명의 연장과 의학의 발달 등으로 건강한 노년 생활에 대한 욕구가 커지면서 남성의 갱년기 증상이 발견되기 시작했다. 특히 20대에 최고조로 증가하는 남성 호르몬(테스토스테론)이 점차 줄어들다가 40~55세 사이에 급격히 감소하면서 여러 가지 신체적, 정신적, 심리적 변화가 나타난다. 남성호르몬 감소의 첫 번째 징후는 부부관계에 관심이 없어지고, 좀 더 진행되면 만성피로를 느끼고 얼굴이 달아오르거나 식은 땀을 흘리며 손발이 저리기도 하다. 그리고 감정이 잘 조절되지 않아 사소한 일에도 짜증을 내게 되는데, 남성 호르몬 부족 때문에 나타나는 이러한 증상들을‘남성 갱년기’라 한다. 이번 호에서는 서울아산병원 비뇨기과 안태영 교수와 성의학클리닉 연구소 강동우 전문의의 도움으로 남성 갱년기에 관해 자세히 알아본다.

• Proceedings of the KSCN Conference
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• 2003.05a
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• pp.125-125
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• 2003

비만인구의 증가는 전 세계적인 문제이며, 우리나라도 비만인구의 증가와 함께 인구 전반의 체질량지수가 증가하고 있다. 여성의 경우 폐경을 맞이하면서 호르몬의 변화 등으로 비만 발생율이 높아지는데, 폐경 후 비만은 만성퇴행성질환 등 여러 질병의 원인이 될 수 있으나, 골밀도에 있어서는 체질량지수와 양의 상관관계를 보인다는 결과와, 어느 수준 이상의 체질량지수 증가는 골밀도에 좋지 못한 영향을 미친다는 상반된 결과들이 제시되고 있다. (중략)

• Journal of the Korea Convergence Society
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• v.13 no.3
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• pp.337-343
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• 2022

The aim of this study was to evaluate anxiety, depression and stress in women with polycystic ovary syndrome(PCOS) and to investigate the risk factors related to psychological difficulties. Sixty women with PCOS were evaluated for level of psychological stress using Beck depression inventory(BDI) and Depression anxiety stress scale(DASS) questionnaire. Serum antimullerian hormone, total testosterone, lutenizing hormone, follicle stimulating hormone, estradiol, lipid profile and 75g oral glucose tolerance test were measured. Thirty healthy women served as the control. Fifty two women with PCOS and 29 healthy women completed a questionnaire. Women with depression who scored >13 by BDI and >10 by DASS were 38.5 %, women with anxiety who scored >8 by DASS were 23.1 %, and women with stress who scored >15 by DASS were 30.8 %, which were significantly higher than control. In PCOS women, total testosterone, LH and AMH were significantly correlated with depression and stress. Weight, body mass index and waist-hip ratio were also significantly correlated with depression. In women diagnosed as diabetes and hyperlipidemia, depression and stress were significantly prevalent. Women with PCOS seemed to be more vulnerable to depression, anxiety and stress. Early diagnosis and management should be considered.

• KSBB Journal
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• v.17 no.4
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• pp.409-415
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• 2002

A certain group of phytochemicals such as isoflavone have been proven to act as a phytoestrogen. After thorough the study of different bibliographic herbs excluding soybeans, dates, pomegranates, and other publicized plants, three different edible herbs by Korean Food Regulation were extracted for the animal study on the effect of estrogen replacement. The herbal extract(FGF271) has been orally administered into 51 weeks old partial ovariectomized rats for 5 weeks with the different dosages of 100 and 1,000 mg/kg, respectively. It was observed that 1) serum estrogen level was increased in both 100 and 1,000 mg/kg group, 2) the distension of uterus was made dose dependently and significantly different in 1,000 mg/kg group (p.0.05) from control in the gross findings, 3) the weight of uterus was increased in 1,000 mg/kg group, and 4) the action on reproductive tissues was clear in the microscopic findings in terms of hyperplasia of endometrial epithelial cell, cystic change of submucosa, dilatation of uterus (significantly increased in 1,000 kg/mg), and follicular cystic changes in ovary. As a result, FGF271 seemed to act as a phytoestrogen by inducing the change in ovary and uterus and by increasing the serum estrogen concentration.

• Journal of the Korean Applied Science and Technology
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• v.37 no.4
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• pp.878-892
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• 2020

The purpose of this study is to explore the effects of pregnant women's taking of probiotics and pilates exercise on Postnatal women's body composition, gut-microbiota, obesity hormones, blood lipid, inflammatory cytokine. Overall clinical trial procedures are as follows. First, a total of 15 pregnant women were classified into 3 groups, probiotics intake+exercise group(PEX, n=5), exercise group(EX, n=5), and control group(CON, n=5). The PEX and EX groups participated in the pilates exercise twice a week for eight weeks, with 10 min for warm-up, 30 min for main exercise and 10 min for cool-dawn. The probiotics had to take one capsule a day on its empty stomach every day. The results showed that intestinal harmful bacteria were inhibited after childbirth in PEX group, and body fat, WHR reduction. There were also positive effects on the decrease of leptin hormone in PEX group and on IL-6, TNF-a levels. The caesarean section ratio of CON group compared to PEX and EX group was found to be high. Conclusion pregnant women's probiotics intake and pilates exercise will be effective in women's abdominal fat reduction after childbirth, and will have positive effects on inflammatory levels and appetite control hormones, which will be effective in preventing and treating obesity for after childbirth.

• Clinical and Experimental Reproductive Medicine
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• v.12 no.1
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• pp.31-40
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• 1985

월경주기 중 황체기가 짧은 여성 즉 황체기 단축현상을 가진 한국여성(SLP) 의 특성을 조사하고 진단하는 방법을 개발하기 위하여 본 실험을 행하였다. 재료는 정상 월경주기를 가진 12명의 여성에서 26주기와 8명의 황체기 단축현상을 가진 여성에서 17주기를 선택하였다. 기상후 첫 오줌에서 steroid glucuronides의 농도를 측정하여 비교한 결과는 다음과 같았다. SLP 의 estrone -3 -glucuronide ($E_1G)의 농도는 초기 여포기와 황체기 동안 정상인에 비하여 현저히 낮았다. 또한 SLP 의 전 월경기 중 pregnanediol-$3{\alpha}$-glucuronide($P_2G$)의 농도 역시 유의성있게 낮았다. 그러나 $E_1G/P_2G$의 비율은 여포기가 황체기에 비하여 현저히 높았고, SLP 여성의 비율이 정상인 보다 각 월경주기 중 유의성있게 높았다. 위의 결과로 보아 $E_1G$, $P_2G$및 $E_1G/P_2G$의 농도차로 황체기 단축현상을 가진 여성을 진단 하고 또 치료시 난소의 기능조절에 이욜될 수 있을 것으로 사려된다.

• Women's Health Nursing
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• v.23 no.4
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• pp.256-264
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• 2017

Purpose: The purpose of this study was to examine factors associated with behaviors of mothers that expose their infants to endocrine disruptors. The PROCEED model was used as a theoretical basis for the study. Methods: This correlational study included 120 mothers with infants between the ages of 1 month to 36 months. Participants were recruited through the maternal community web-site of mothers of infants in W city. Results: There was a significant negative correlation among experience of mothers who had participated in environmentally friendly activities, the health status of the infants perceived by the mother, and behaviors of mothers that exposed infants to endocrine disruptors. The factors based on PROCEED model explained 15.3% of the behaviors by mothers that exposed infants to endocrine disruptors. Conclusion: It is necessary to develop and provide educational programs that include detailed information on relationship of endocrine disruptors to children's health.

• The Journal of Korean Obstetrics and Gynecology
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• v.15 no.4
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• pp.193-201
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• 2002

Purpose : Premature ovarian failure, characterized by amenorrhea or oligomenorrhea, estrogen defieciency and elevated gonadotropins in woman less than 40 years of age, affects approximately 1% of woman and is associated with autoimmune phenomena or genetic abnormalities, but mostly idiopathic. This disease is loss of ovarian function seems not to be always permenent. Method : We investigated herb medication was effective in patient of premature ovarian failure. Results: Signs and symtoms of estrogen deficiency were improved and mensturation occurred monthly and the elevated during treatment of herb medication. As a result of our case recovering of ovarian function, we hope more investigtions about treating premature ovarian failure by oriental medicine will be gained.