• Journal of Korean Medical classics
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• v.20 no.1
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• pp.75-84
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• 2007

본논문천명(本論文闡明) "류경(類經)" 위안등창익의학사상적천원(爲安藤昌益醫學思想的泉源), 종안등창익학습(從安藤昌益學習) "류경(類經)" 적계단래비판(的階段來批判) "류경(類經)", 집중적연구관찰극복계단적전화과정(集中的硏究觀察克服階段的轉化過程). 안등창익(1703-1762)재일본강호시대시개즉독창우진보적사상가야시중의사(安藤昌益(1703-1762)在日本江戶時代是個卽獨創又進步的思想家也是中醫師). 타통과(他通過)'자연진영도(自然眞營道)'등굉대적저술(等宏大的著述), 부근논술료사회철학급자연철학(不僅論述了社會哲學及自然哲學), 이차재일본의학사상난이발현적독특적의학사상급여체계화(而且在日本醫學史上難以發現的獨特的醫學思想給與體系化). 타이유교비판위기초(他以儒敎批判爲基礎), 비판중국의학대유유의적경향(批判中國醫學帶有有醫的傾向), 여후세파(與後世派), 고방파적맥락야부동(古方派的脈絡也不同), 독자제정일본의학(獨自制訂日本醫學). 타대어중국적음양오행설이진퇴론화사행팔기적호성론래대항(他對於中國的陰陽五行設以進退論和四行八氣的互性論來對抗), 대어'내경'적국가유추(analogy)내장관이유기생체적내장관래대치(對於‘內經’的國家類推(analogy)內臟觀以有機生體的內臟觀來對峙). 병차비판숙명론적운기론이제창대소우주론적생태학(ecology)적의학. 이차간래(以此看來), 안등창익적의학사상시이비판'내경'위개단(安藤昌益的醫學思想是以批判‘內經’爲開端). 아문가이통과안등창익적운기론적비판래명백(我們可以通過安藤昌益的運氣論的批判來明白), 타대'내경'적이해시의거장개빈적 "류경"(포괄'도익'화'부익')(他對'內經'的理解是依據張介賓的"類經"(包括'圖翼' 和 '附翼')). 안등창익일방면계승장개빈적운기론영일방면야지유비판적태도. 타주장십기래대체십간(他主張十氣來代替十干), 인위군화여상화시파군신적상하관계정당화(認爲君火與相火是把君臣的上下關係正堂化), 인이반대저양적사고방식(因而反對這樣的思考方式). 병차안등창익부정기성적음운학, 제창자연적운도(提唱自然的韻道), 아문가이확인대어타적사상장개빈적 "류경" 시위중요적기초(我們可以確認對於他的思想張介賓的 "類經" 是爲重要的基礎).

• Journal of the Korea Convergence Society
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• v.10 no.11
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• pp.411-417
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• 2019

The Korea Convergence Society. The main purpose of this study is to analyze and categorize Art Infusion, and to examine the effects of consumers' advertising on attitude and memory information. As a result, first, there were no statistical differences according to the type of recall according to the way of using famous paintings. However, the product diagnosis and advertisement diagnosticity according to the way of using the famous paintings showed positive evaluation in the reinterpreted famous paintings. Second, in the case of recalls according to the frequency of exposure to famous paintings, the exposure of famous painting advertisements was higher than that of the highly exposed painting advertisements. Third, when comparing the interaction effect on the recall of advertisements, the high-exposure advertisements reinterpreted by the camera showed the highest recall. The results of this study are expected to contribute to strategic measures that can positively change consumer memory and attitudes according to the way of using famous paintings.

• Korean Journal of Breeding Science
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• v.42 no.2
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• pp.188-194
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• 2010

This experiment was conducted to characterize the inheritance of petal color, flower-eye color, flower shape, leaf variegation pattern, and leaf-end shape in Cyclamen persicum. The segregation of $F_2$ and backcross populations from crosses between inbred lines was tested for Mendelian inheritance mode. From four different combinations of crosses, it was found that the petal color was controlled by a single incomplete dominant gene. The other characters, flower-eye color, flower shape, leaf variegation pattern and leaf-end shape were confirmed to be controlled by single complete dominant genes.

• 한국노년학
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• v.28 no.4
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• pp.1213-1225
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• 2008

The purpose of this study was to determine psychosocial variables of exercise behaviors for old adults. A major research problem identified through theory of planned behavior and it's empirical data: Do cognitive-social variables(health risk perception, self-efficacy, group conformity, exercise attitude) significantly mediate exercise behaviors(intention, action, maintenance)? A total of 453 older adults above 65 years(171 males and 282 females) who were enrolled in various classes were randomly selected at adults centers in Seoul. Participants completed a battery of questionnaires including the psycho-social variables(health risk perception, self-efficacy, group conformity, exercise attitude) and exercise behaviors(intention, action, maintenance). The results of statistical procedures(e.g., hierarchical multiple regression) indicated self-efficacy and exercise attitude significantly predicted exercise intentions of older adults. Exercise intention was a significant predictor of action, and action was a significant predictor of exercise maintenance. In discussion, various psycho-social mechanisms were provided to interpret the results of this study, and future directions were suggested.

• Proceedings of the Korea Information Processing Society Conference
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• 2010.11a
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• pp.656-659
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• 2010

오늘날 현대 사회에서 여가생활시간이 늘어나고 이에 따라 사람들은 잦은 커피타임을 갖고 있으며 이로 인해 커피의 섭취량이 날로 늘어나고 있다. 날로 늘어나는 커피 섭취량과 같이 커피의 주성분인 카페인 섭취량 또한 날로 증가 하고 있다. 따라서 본 논문에서는 카페인의 성분과 효능, 인체에 미치는 영향 정도와 음성에 관여하는 정도 등에 대한 결과를 추출하여 실질적으로 카페인이 음성에 미치는 요소를 분석하였다. 이를 위해 본 논문에서는 음성분석 프로그램인 Praat를 사용하였으며 성대의 변화량과 몸 속의 공명음인 Formant를 실험 요소로 적용하였다. 데이터 자료에서 유용성을 입증하고 문제점 해결에 대해 분석하였으며 실험에 의해 제안한 방법의 활용성을 입증하는 연구를 수행하였다.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.258-258
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• 2022

물넘이 형식에는 수문과 밸브로 조절할 수 있는 조절형식, 개수로 및 관수로 형식의 자연적으로 수위조절이 되는 비조절형식, 레버린스(Labyrinth), 피아노건반(Piano Key Weir), 사이펀(Siphon) 등의 특수형식으로 구분할 수 있다. 이 중에서 피아노건반 물넘이는 레버린스 물넘이를 피아노건반 모양으로 개량한 것으로 2003년 알제리 Biska 대학의 Quamane 교수에 의해 제안되었다. 제한된 물넘이 폭에 물넘이의 길이를 연장하여 방류능력을 증가시키는 효과를 나타내는 물넘이 형식으로 여수로의 월류수심을 낮게 유지하면서 방류량을 증가시킬 수 있다. 피아노건반 물넘이는 2006년에 프랑스에서 최초로 적용되었으며, 현재까지 약 30여 지역(프랑스, 베트남, 호주 등)의 댐에 적용되었다. 본 연구에서는 국내 저수지를 대상으로 여수로에 피아노건반 물넘이를 적용하여 방류능력과 수리적 안정성 검토를 위해 농어촌연구원 국제융합수리시험센터에서 수리모형실험을 수행하였다. 농어촌연구원은 2018년도에 기존 수리모형실험 시설을 확장하여 가로 250m, 세로 102m의 국내 최대규모의 실내 수리모형실험 시설을 준공하였고, 대형유사순환수로, 고정식 급경사수로, PIV 전용실험수로 등 기능별 7종의 실험수로를 갖추고 있다. 수리실험은 Froude 상사에 의한 축척을 적용하여 모형을 제작하였고, 기존의 수리시설과 하류하천까지 포함하여 70m(L)×20(B)×2m(H) 규모이다. 실험은 유량을 다양하게 변화시키면서 수위-방류량을 검토하였고, PMF 홍수위에서 방류량이 배제 가능한지 검토하였다. 또한, 물넘이의 안정성 검토를 위한 접근유속을 게측하였고, 물넘이를 통해 월류하는 흐름의 유황을 분석하여 수리학적으로 안정한 흐름이 발생하는지 검토하였다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5A
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• pp.927-934
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• 2006

According to the high demand of concrete structures with high performance, various studies have examined on the high performance concrete, especially high strength concrete. Various admixtures are required to produce high strength concrete and silica fume has been the most popular admixture. Recently, however, metakaolin, which is similar to silica fume in properties but cheaper, has been introduced to high strength concrete. This study conducted XRD and SEM analyses on a cement paste specimens to clarify metakaolin's performance in pozzolan. Additionally, a concrete specimens were fabricated to analyze its pore structure using Mercury Intrusion Porosimetry and its correlation to the compressive strength. In result, it was found that the average diameter of pore reduced and compressive strength increased as more metakaolin content was added. In addition, a regression analysis of $10nm{\sim}10{\mu}m$ pore and compression strength revealed that these two factors had a high correlation of about 0.93 and 10~15% of metakaolin replacement was most appropriate.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.495-502
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• 2019

A typical cerebrovascular disease among cerebrovascular diseases is vascular diseases such as cerebral infarction, cerebral hemorrhage, cerebral aneurysm, cerebrovascular stenosis. If the disease occurs and causes cerebral damage, it may be difficult to recover completely. So that, Must continue to perform health care through examination early. In particular, Because most cerebrovascular disease examining use radiation equipment and Thus this study was to find out how to select about the optimal examining method and X-ray dose decrease method among different examining method though comparison and analysis for the entrance surface dose (ESD) on cerebrovascular examining with Trance Femoral Cerebral angiography (TFCA) and Cerebral Computed Tomographic Angiography (CCTA). Also, want to find out how to select about the optimal examining method for worried patient that contrast medium side effect though measuring and evaluating for contrast usage. Data were collected from 70 patients (43 males and 27 females) who underwent CCTA at Yeosoo region hospital from June 2018 to December 2018 and 61 patients (34 males and 27 females) who underwent TFCA at Pyeongtaek region hospital from June 2018 to November 2018. ESD analysis method collected retrospective data though M-view and PACS PLUS program, Used contrast usage measuring method did reality measuring method. In the analysis using SPSS, the ESD of TFCA was $245.74{\pm}71.91$, which was $32.05{\pm}7.74$ lower than the dose of $277.79{\pm}79.65$ of CCTA ESD, and statistically significant at t = 3.249, p = 0.017 (p<0.05). As a result of the comparison of the total amount of contrast agent, the mean contrast agent used in TFCA was $55.05{\pm}17.68ml$, which was about 14.95 smaller than the amount of contrast agent used in CCTA, and statistically significant t = -4.548, p<0.001. In conclusion, the ESD of TFCA was statistically significantly lower than that of CCTA, and also the used contrast usage was significantly tiny than that of CCTA. Therefore, Select the method to increase the utilization of TFCA for cerebral disease examining, we can consider X-ray dose decrease method at the same time as to decrease side effect of contrast medium.

• The Korean Journal of Pharmacology
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• v.32 no.1
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• pp.13-21
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• 1996

Intracellular calcium concentration ($[Ca^{2+}]_i$) may play a crucial role in a variety of neuronal functions. Here we report that in primary culture of mouse cerebellar granule cells nicotinic acetylcholine receptors (nAChRs) are expressed in a specific developmental stage and involved in the regulation of intracellular calcium homeostasis. Nicotine-mediated calcium responses were measured using $^{45}Ca^{2+}$ or fluorometrically using the calcium-sensitive fluorescent dye fura-2. Maximal uptake of $^{45}Ca^{2+}$ evoked by nicotine in mouse cerebellar granule cells were revealed $8{\sim}12$ days in culture. In contrast, nicotine did not alter the basal $^{45}Ca^{2+}$ uptake in cultured glial cells. In cerebellar granule cells nicotine-evoked $^{45}Ca^{2+}$ uptake was largely blocked by the NMDA receptor antagonists. Glutamate pyruvate transaminase (GPT). which removes endogenous glutamate, also prevented nicotine effects, implying the indirect involvement of glutamate in nicotine-mediated calcium responses. Fluorometric studies using fura-2 showed two phases of nicotine-evoked $[Ca^{2+}]_i$ rises: the initial rising phase and the later plateau phase. Interestingly, the NMDA receptor antagonists and GPT appeared to inhibit only the later plateau phase of nicotine-evoked $[Ca^{2+}]_i$ rises. The present results imply that nicotine mediated $^{45}Ca^{2+}$ uptake and $[Ca^{2+}]_i$ rises are attributed to the calcium fluxes through both nAchRs and NMDA receptors in a time-dependent manner. Consequently, nAChRs may play an important role in neuronal development by being expressed in a specific developmental stage and regulating the intracellular calcium homeostasis.

• Journal of Ginseng Research
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• v.23 no.4
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• pp.222-229
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• 1999

Histopathological study has been carried out to elucidate the protective effect of Korean red ginseng water extract (KRG-WE) on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced acute toxicity in male guinea pigs. Forty male guinea pigs ($200{\pm}20g$) were divided into 4 groups: normal controls (group 1) received vehicle and saline; group 2 (single TCDD-treated) received TCDD (5 ${\mu}g/kg$, single dose) and saline; group 3 received KRG-WE (200 mg/kg, i.p.) for 2 weeks starting 1 week before TCDD-exposure; group 4 received same dose of KRG-WE for 7 days from the day of TCDD-exposure. Weights of liver, testis, kidney, spleen and lung of the TCDD-exposed guinea pigs were significantly decreased. Thymus was severely shrunken, thereby could not be distinguished from adipose tissue in group 2 animals. Focal interstitial inflammation and fibrosis were observed from the lung parenchyma of group 2 animals. Furthermore, moderate swelling of hepatocyte, diffused aggregates of hemosiderin-laden macrophages from the Prussian blue stained spleen, marked decrease in spermatogenesis, and pyknotic and degenerative changes in the renal tubules were observed from intestinal organs of group 2 animals. On the other hand, histopathological damage was moderately to markedly alleviated in groups 3 and 4, but pretreatment of KRG-WE was more effective than the simultaneous treatment. In particular, TCDD-induced testicular atrophy was significantly attenuated by KRG-WE (p<0.01). From these results, it could be suggested that Korean red ginseng might be a useful herb that prevented TCDD-induced toxicity on liver, testis, kidney and spleen.