• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.251-251
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• 1994

1차년도에서 이미 확립한 다양한리포좀의 제조 방법에 따라간세포를표 적하기 위해 이들 리포좀의 조성에 galactocercbroside를 함유시켜 targeted liposomes을 제조하였다. 표적리포좀의 제조 방법에 따른 봉합율 (cncapsulation)과 안정성을 조사했을 때, freezing-thawing 과정을 거친 리포좀이 encapsulation 과 stability가 가장 뛰어남을 알 수 있었다. In vitro 간세포 표적능력을 in vitro cell culture system에서 간세포 cell line (Hep G2, 2.2.15과 다른 cell line (Vero E6, J82)에 대한 표적리포좀과 control liposomes의 uptake를 FTTC 또는 CF 형광으로 측정했을 때, 표적리포좀이 간세포 cell line에 더 많이 uptake하는 것을 알았다. In vivo 실험에서는 6 - 8 주령의 mouse tail vain에 표적리포좀과 control liposomes을 주사하여 각 장기에 존재하는 리포좀의 양을 형광으로 측정했을 때, 표적리포좀 (targetcd liposomes)이 다른 장기에 비해 liver에 선택적으로 많이 분포함을 알수있었다. 또한 간암의 효과적인 치료를 위해 간세포와 암세포를 동시에 표적할 수는 double targeting liposomes을 design 하였다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.2
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• pp.137-141
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• 2006

컨테이너를 선박에 양 ${\cdot}$ 적하하는 장비인 컨테이너 크레인은 차폐물이 거의 없는 항만에 설치되며, 계류시 전체 높이가 100m에 달하게 되므로 풍하중에 매우 큰 영향을 받게 된다. 따라서 본 연구에서는 컨테이너 크레인에 작용하는 풍하중을 정확하게 분석하기 위하여 풍력실험과 유한요소해석, 전산유동해석을 통하여 컨테이너 크레인이 받는 풍하중을 분석하였다. 우선 대기 경계층 풍동을 이용한 풍력실험을 수행하여 풍향 및 기계시 위치에 따른 풍력계소를 측정하고, 이를 이용하여 컨테이너 크레인이 받는 풍하증을 분석하였다. 그리고 풍력실험에서 얻어진 반력비를 이용하여 유한요소해석을 수행함으로써 컨테이너 크레인에 작용되는 풍하증과 지지점에서의 전도력을 계산하였다. 마지막으로 전산유동해석을 수행함으로써 컨테이너 크레인 주위의 유동현상을 고찰하고 컨테이너 크레인 표면에서의 풍압력과 풍하중을 실험결과와 비교 ${\cdot}$ 분석하였다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2020.11a
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• pp.131-132
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• 2020

자율운항선박 지원 6종서비스는 자율운항선박의 도입에 따른 항계 및 협수로 내에서 터미널까지 안정적으로 통항과 자율적인 이·접안 및 화물 적·하역이 가능하도록 안전운항을 지원하는 기술을 의미한다. 자율운항선박 지원 6종서비스에는 근접 선박에 대한 연속 회피가 가능한 자율운항 지원 서비스, 인공지능 센서 융합을 통한 접·이안 및 계류 지원 서비스, 스마트 해상 물류 프로세스를 위한 화물 양·적하 및 선박 입출항 지원 서비스, PSC 점검율 제고를 위한 PSC 점검 지원 서비스, 선박의 주요 기기를 육상에서 관찰하기 위한 상태모니터링 지원 서비스, 해양사고 발생 시 신속한 조치를 위한 사고대응 지원 서비스로 이루어져 있다. 이 연구에서는 개발되는 안전운항 지원서비스 6종의 실용성 및 현장 적용 가능성을 테스트하기 위한 실선박 기반의 검증 시나리오를 개발하고 6종 서비스의 육상 시범 운용을 위한 인프라를 구축하고자 하였다.

• Journal of Korea Multimedia Society
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• v.13 no.1
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• pp.17-29
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• 2010

A container terminal productivity is maximized by a minimized time for processing containers. So, we have been elevated the container terminal productivity through an improvement of computing system, but there are a limitation because of problems for transportation management and method. A Y/T(Yard Tractor), which is a representative transportation, is able to do only one process, loading or unloading, at one time. So if the Y/T can do loading and unloading step by step at a same time, the processing time would be shortened. In this paper, we proposed an effective operating process of Y/T(Yard Tractor) Multi-Cycle System by applying RTLS(Real Time Location System) to Y/T(Yard Tractor) in order to improve the process of loading and unloading at the container terminal. For this, we described Multi-Cycle System. This system consists of a real time location of Y/T based on RTLS, an indicating of Y/T location in real time with GIS technology, and an algorithm(Dijkstra's algorithm) of the shortest distance. And we used the system in container terminal process and could improve the container terminal productivity. As the result of simulation for the proposed system in this paper, we could verify that 9% of driving distance was reduced compared with the existing rate and 19% of driving distance was reduced compared with the maximum rate. Consequently, we could find out the container performance is maximized.

• Journal of Navigation and Port Research
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• v.33 no.10
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• pp.723-734
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• 2009

Container Vessel is becoming larger and faster thanks to the rapid growth of global trade and development of technology. Therefore, 15,000TEU vessel is expected to be ordered in near future. Every nations in north-east Asia are facing strong competition to be logistics hub to get the initiatives of logistics in response to the rapid change of logistics environment. According to the globalization of economy and major ports in this region also are trying to catch big shipping line for their survival. Considering above circumstances of the advent of ultra-large container vessel and spoke-and-hub strategy, it is inevitably necessary to make a fast and accurate vessel job in the terminal in order to be a leading port To meet this objective, current vessel planning system has to be improved innovatively. Therefore, this thesis propose multi distributed vessel planning system which enables multi loading/discharging planning with several planner simultaneously for faster and more accurate than existing planning and enhances quality of planning through information sharing among planners. Also this thesis uses simulation through Arena to verify the efficiency of this multi-distributed vessel planning system.

• Culinary science and hospitality research
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• v.22 no.4
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• pp.128-142
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• 2016

This study was carried out to investigate the effect of memory impairment in rats fed alcohol liquid diets. The rats were randomly divided into 4 groups. While the control(C) group received a diet containing 12% of the daily calories with isocarbohydrate, the other groups received a diet containing 12% of the daily total calories with 36% Soju (A), 25% Cynanchi wilfordii radix liquors (WA), and 25% Polygoni multiflori radix liquors (RA) for 6 weeks. After 6 weeks, ADH activity in the brain tissue of the Group A was found to be significantly lower than Group C but significantly higher than both Groups WA and RA(p<0.05). ADLH activity was revealed to be the highest in the Group WA (p<0.05). The concentration of acetaldehyde, a highly toxic metabolite, was the highest in the Group A, but its concentration decreased significantly if fed a liquid diet containing WA. The concentration of acetylcholine, which has a high correlation with memory impairment, was significantly lower in Group A, although Group RA group was the highest compared to the other groups (p<0.05). AChE activity of the Group A was higher than Group C but lower in Groups WA and RA (p<0.05).

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.203-208
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• 2004

The objective of this study is to analyze the efficiency of marshalling work using ATC(automated transfer crane) for ACT(automated container terminal). It is important fact to assignment of containers, because the character of ACT which block layout is vertical for berth and there are four other works which are inbound, oubound, loading and unloading in one block. And then there is need which assignment of containers with remarshaling work using ATCs in one block. Therefore, we analyze the efficiency of remarshaling work using simulation and suggest the assignment methodology of containers in yard

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2010.10a
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• pp.110-111
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• 2010

Recently, container terminal managers make an experiment on the double cycle and dual cycle operation, which ship loading and unloading were carried out simultaneously, for increasing the productivity of quay side. However, if we make an experiment on dual cycle operation in a real job site, the efficiency is poor up to terminal operation method as YTs(Yard Tractors)' allocation method, QCs(Quay Cranes)' working speed, and position of export containers. So, this paper examine more efficient terminal operation method, when terminal uses dual cycle operation.

• The Journal of the Korea Contents Association
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• v.9 no.8
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• pp.84-90
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• 2009

In this paper, the RFID-based ad-hoc network is presented for the efficient yard management of the container terminal. The loading and unloading work is performed through the ad-hoc communication between YT and GC, YT and TC within the yard without the control of the central server. That makes the efficient operation of the yard with real task correspondence. Using the location information of the RFID tag, we have proposed the routing protocol which is suitable for the yard environment of the container terminal. The performance evaluation has been carried out through the network simulator and gained an effective results.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2007.06a
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• pp.721-723
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• 2007

Recently, the size and location of the acquired container image while the container is loading and unloading in Harbors is not fixed. And it is difficult to get a good image for recognition because of the variation of external environment as those the size of container and where the yard-tractor stop is. In this paper, we estimate where the container ISO-code set is using Top-hat transform from realtime images and get an image to recognize container ISO-code using PAN/TILT/ZOOM camera. We extract the container ISO-code using Top-hat transform and Histogram projection. After binarization, we extract each character from complex background using labeling. We use BP(Backpropagation Network) to recognize extracted characters.