• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.29 no.11A
• /
• pp.1263-1270
• /
• 2004

A low-power 64-point FFT/IFFT processor core is designed, which is an essential block in OFDM-based wireless LAM modems. The radix-2/418 DIF (Decimation-ln-Frequency) FFT algorithm is implemented using R2SDF (Radix-2 Single-path Delay Feedback) structure. Some design techniques for low-power implementation are considered from algorithm level to circuit level. Based on the analysis on infernal data flow, some unnecessary switching activities have been eliminated to minimize power dissipation. In circuit level, constant multipliers and complex-number multiplier in data-path are designed using truncation structure to reduce gate counts and power dissipation. The 64-point FFT/IFFT core designed in Verilog-HDL has about 28,100 gates, and timing simulation results using gate-level netlist with extracted SDF data show that it can safely operate up to 50-MHz＠2.5-V, resulting that a 64-point FFT/IFFT can be computed every 1.3-${\mu}\textrm{s}$. The functionality of the core was fully verified by FPGA implementation using various test vectors. The average SQNR of over 50-dB is achieved, and the average power consumption is about 69.3-mW with 50-MHz＠2.5-V.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• v.45 no.4
• /
• pp.12-18
• /
• 2008

Researches on particle physics have benefited our everyday life in many aspects. They have tested the safety of the objects we use everyday, conducted experiments to examine harmful environments to man, and treated diseases. Despite the usefulness of particle physics in a range of fields, however, it's difficult to conduct researches and experiments directly. But the advancements in the computer industry have allowed for experiments of particle physics in virtual simulations. One of the foremost simulation libraries for particle physics that have been researched actively these days, Geant4 has been put to diverse uses in particle physics. This study designed GUI so that physicists, who were not good at programming, could use a simulation library faster, more accurately, and more conveniently. It also developed the Geant4Editor, a simulation automation framework. The advantages of the Geant4Editor include automatic generations of essential classes in a simulation using Geant4 libraries and real-time reflection of user demands in a simulation. It also allows for efficient management of resources(user-created data) through the Data Manager.

• Journal of Korea Society of Industrial Information Systems
• /
• v.24 no.6
• /
• pp.43-53
• /
• 2019

In recent years, there have been many cases of damage to indoor air hazardous materials, and major damage due to the lack of quick action. In this regard, the system is intended to establish for sending push messages to the user's mobile when the concentration of hazardous substances is exceeded. This system extracts data with IoT system such as Arduino and Raspberry Pi and then constructs database through MongoDB and MySQL in cloud computing system. The database is imported through the application server using NodeJS and sent to the application for visualization. Also, when receiving signals about a dangerous situation in IoT system, push message is sent using Google FCM library. Mobile application is developed using Android Web view, and page to enter Web view is developed using HTML5 (HTML, Javascript CSS). The application of this system enables real-time monitoring of indoor air-dangerous substances. In addition, real-time information on indoor/outdoor detection location and concentration can be sent to the user's mobile in case of a risk situation, which can be expected to help the user respond quickly.

• Journal of Life Science
• /
• v.25 no.6
• /
• pp.656-662
• /
• 2015

Natural products and natural product structures play a general and highly significant role in drug discovery and development process because it has various merits and potentials for new drug source that have extensive clinical experience, development time contraction, excellent stability and safety. In several neurological disorders, neuronal death and excessive activation of microglia (neuro-inflammation) are observed. A number of drug discovery-related neuronal cell death and neuro-inflammation was studied from natural products, respectively. However, until now, it has not been possible to study dual-protection molecules recorded in the Natural Product library. In the present study, using the natural product-derived library of the Institute for Korea Traditional Medical Industry, we investigated dual-protective molecules against glutamate (a classical excitatory neurotransmitter)-induced oxidative stress mediated neuronal cell death and LPS-induced excessive activated microglial cells (immune cells of the brain). Chrysophanol, extracted from Rheum palmatum, had dual-protective effects against both glutamate-induced neuronal cell death and LPS-induced NO production, triggering proinflammatory cytokines and microglia activation and resulting in neuroinflammation. Flow-cytometry analysis revealed that chrysophanol had a scavenger effect, scavenging glutamate- and LPS-induced reactive oxygen species (ROS) produced by neuronal and microglial cells, respectively. Based on the present study, chrysophanol may have an important protective role against neuronal cell death and neuroinflammation in the brain. The results may be helpful for studying drug development candidates for treating central nervous system disorders.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.8 no.2
• /
• pp.430-439
• /
• 2004

This paper describes a design of 8192/2048-point FFT/IFFT processor (CFFT8k2k), which performs multi-carrier modulation/demodulation in OFDM-based DVB-T receiver. Since a large size FFT requires a large buffer memory, two design techniques are considered to achieve memory-efficient implementation of 8192-point FFT/IFFT. A hybrid structure, which is composed of radix-4 single-path delay feedback (R4SDF) and radix-4 single-path delay commutator (R4SDC), reduces its memory by 20% compared to R4SDC structure. In addition, a memory reduction of about 24% is achieved by a novel two-step convergent block floating-point scaling. As a result, it requires only 57% of memory used in conventional design, reducing chip area and power consumption. The CFFT8k2k core is designed in Verilog-HDL, and has about 102,000 Bates, RAM of 292k bits, and ROM of 39k bits. Using gate-level netlist with SDF which is synthesized using a $0.25-{\um}m$ CMOS library, timing simulation show that it can safely operate with 50-MHz clock at 2.5-V supply, resulting that a 8192-point FFT/IFFT can be computed every 164-${\mu}\textrm{s}$. The functionality of the core is fully verified by FPGA implementation, and the average SQNR of 60-㏈ is achieved.

• Journal of the Korean Institute of Gas
• /
• v.22 no.6
• /
• pp.136-143
• /
• 2018

Cellular automata have been applied to simulations in many fields such as astrophysics, social phenomena, fire spread, and evacuation. Using cellular automata, this study develops a model for consequence analysis of the dispersion of hazardous chemicals, which is required for risk assessments of and emergency responses for frequent chemical accidents. Unlike in cases of detailed plant safety design, real-time accident responses require fast and iterative calculations to reduce the uncertainty of the distribution of damage within the affected area. EPA ALOHA and KORA of National Institute of Chemical Safety have been popular choices for these analyses. However, this study proposes an initiative to supplement the model and code continuously and is different in its development of free software, specialized for small and medium enterprises. Compared to the full-scale computational fluid dynamics (CFD), which requires large amounts of computation time, the relative accuracy loss is compromised, and the convenience of the general user is improved. Using Python open-source libraries as well as meteorological information linkage, it is made possible to expand and update the functions continuously. Users can easily obtain the results by simply inputting the layout of the plant and the materials used. Accuracy is verified against full-scale CFD simulations, and it will be distributed as open source software, supporting GPU-accelerated computing for fast computation.

• Journal of Internet Computing and Services
• /
• v.23 no.1
• /
• pp.49-68
• /
• 2022

The operation system of a shipping company is still maintaining the mainframe based terminal access environment or the client/server based environment. Nowadays shipping companies that try to migrate it into a web-based environment are increasing. However, in the transition, if the design is processed by the old configuration and knowledge without considering the characteristics of the web-based environment and shipping business, various security vulnerabilities will be revealed at the actual system operation stage, and system maintenance costs to fix them will increase significantly. Therefore, in the transition to a web-based environment, a security design must be carried out from the design stage to ensure system safety and to reduce security-related maintenance costs in the future. This paper examines the characteristics of various threat modeling techniques, selects suitable modeling technique for the operation system of a shipping company, applies data flow diagram and STRIDE threat modeling technique to shipping business, derives possible security threats from each component of the data flow diagram in the attacker's point of view, validates the derived threats by mapping them with attack library items, represents the attack tree having various attack scenarios that attackers can attempt to achieve their final goals, organizes into the checklist that has security check items, associated threats and security requirements, and finally presents 23 security requirements that can respond to threats. Unlike the existing general security requirements, the security requirements presented in this paper reflect the characteristics of shipping business because they are derived by analyzing the actual business of a shipping company and applying threat modeling technique. Therefore, I think that the presented security requirements will be of great help in the security design of shipping companies that are trying to proceed with the transition to a web-based environment in the future.

• Applied Biological Chemistry
• /
• v.50 no.4
• /
• pp.268-275
• /
• 2007

Diversity of the mud flat microbial population in Suncheon Bay was investigated by studying extracellular enzyme activities and 16S rDNA sequences. Four culturable bacterial strains with CMCase, xylanase and protease activities were isolated from the wetland and the mud flat. All the strains produced more xylanase activity than CMCase or protease activity, and the properties of the isolate enzymes from the wetland were similar to those from the mud flat. About 2,000 clones were obtained with the 16S rDNA amplified from the metagenomic DNA isolated from the mud samples. Based on the restriction pattern(s), seventeen clones were selected for base sequence analysis. Of the 17 clones, only 35% (6 clones) were found to be cultured strains and 65% (11 clones) to be uncultured strains. The similarities in the base sequences of the clones ranged from 91.0% to 99.9% with an average similarity of 97.3%. The clones could be divided into 7 groups, Proteobacteria (9 clones, 52.9%), Firmicutes (3 clones, 17.6%), Bacteroidetes (1 clone), Flavobacteria (1 clone), Verrucomicrobia (1 clone), Acidobacteria (1 clone), and Chloroflexi (1 clone). Most of the Proteobacteria clones were gamma Proteobacteria associated with oxidation-reduction of sulfur.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.49 no.3
• /
• pp.193-201
• /
• 2023

Hydrogen peroxide (H₂O₂) is a type of active oxygen species (ROS) that causes oxidative stress in cells and affects cell growth, proliferation, senescence, and death. The purpose of this study is to find active peptides that attenuate cytotoxicity of H₂O₂. A positional scanning synthetic tetrapeptide combinatorial library was screened to predict the sequence of potentially active peptides. As a result of comparing the effect of peptide pools on H₂O₂-induced death of human keratinocytes (HaCaT cells), various active peptide sequences were predicted. Especially, peptides containing cysteine (C) residue were predicted to be active. In follow-up experiments, the cytotoxicity and activity of cysteine-containing peptides of different lengths, such as C-NH₂, CC-NH₂, CCC-NH₂, and CCCC-NH₂ were examined. C-NH₂ and CC-NH₂ showed no significant cytotoxicity up to 1.0 mM, but CCC-NH₂, and CCCC-NH₂ showed relatively strong cytotoxicity. C-NH₂ and CC-NH₂ alleviated H₂O₂-induced cytotoxicity. CC-NH₂ was more cytoprotective compared to C-NH₂, C, N-acetyl cysteine (NAC), and glutathione (GSH). When intracellular ROS was measured by flow cytometry, H₂O₂ increased ROS production, and CC-NH₂ suppressed ROS production more effectively than C-NH₂, and it was as effective as C, NAC, and GSH. This study suggests that CC-NH₂ of the cysteine-containing peptides of different lengths has an antioxidant property that safely and effectively alleviates H₂O₂-induced cytotoxicity and ROS production.