• Title/Summary/Keyword: 안과질환

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Ocular manifestations in Leigh syndrome (Leigh 증후군 환아에서의 안과적 이상 소견)

  • Kim, Kyo Ryung;Byeon, Suk Ho;Lee, Young Mock;Kang, Hoon Chul;Lee, Joon Soo;Kim, Heung Dong
    • Clinical and Experimental Pediatrics
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    • v.53 no.2
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    • pp.163-166
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    • 2010
  • Purpose : Leigh syndrome is a typical type of mitochondrial disease. This study was conducted to analyze the types of ophthalmologic symptoms and results of funduscopy conducted in the ophthalmologic examination of patients with Leigh syndrome. Methods : Funduscopy was conducted on 24 subjects, who were chosen among those diagnosed as having mitochondrial respiratory chain complex defect and who were clinically suitable for the criteria of Leigh syndrome. Their clinical features, ophthalmologic symptoms, and ophthalmologic examination results were retrospectively analyzed. Results : Of the 24 patients with Leigh syndrome, 11 developed ophthalmologic symptoms and no abnormal finding was observed in 13. The most frequent abnormal finding was visual disturbance in 5 patients. Funduscopy revealed abnormal findings in 17 patients; retinal pigmentation was the most frequent abnormality and was seen in 9 patients. Conclusion : Funduscopy can be an important screening test to find ophthalmologic abnormalities among patients with mitochondrial disease (MD), including those patients whose ophthalmologic symptoms are inconspicuous. It is predicted that an improved screening test can be made in the future that will identify risk factors related to ophthalmologic symptoms.

개와 고양이 안과질환에서의 항생제 응용

  • Lee, Sang-Gon
    • Journal of the korean veterinary medical association
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    • v.50 no.2
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    • pp.104-111
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    • 2014
  • 안구표면은 자연스럽게 형성되는 세균집단의 거처로 항시 소독이 되어 있지 않은 상태로 존재한다고 봐야 한다. 예방 또는 치료를 목적으로 사용되는 적절한 항생제를 선택하려면 안구표면에 항시 산재하는 세균들에 관한 것은 물론 병원균에 효력이 있는 약품 그리고 그 약품의 부작용에 관한 사항들을 숙지해야 한다는 것은 수의사로서 자명한 사실이다. 이 글은 문헌들을 토대로 하여 개와 고양이 안구부(眼口部)에 서식하는 세균 그리고 병원균들과 그에 응용해야 할 항생물질들을 사용하는 데 조금이라도 도움이 될 수 있도록 간단히 분류 적절하게 이용할 수 있기를 바라는 마음에서 정리한 것이다.

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An Epidemiologic Survey of Strabismus and Nystagmus in South Korea: KNHANES V (인구역학적 요인에 따른 한국인의 사시 및 눈떨림 유병률 조사: 제5기 국민건강영양조사 자료)

  • Lee, Ji Eun;Kim, Chang Zoo;Nam, Ki Yup;Lee, Seung Uk;Lee, Sang Joon
    • Journal of The Korean Ophthalmological Society
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    • v.58 no.11
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    • pp.1260-1268
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    • 2017
  • Purpose: Strabismus affects any age and represents various functional or non-functional eye problems. This population-based study was conducted to determine the prevalence of strabismus and nystagmus in South Korea according to various sociodemographic factors. Methods: We acquired data from the Korea National Health and Nutrition Examination Survey, a nation-wide cross-sectional survey and examinations of the non-institutionalized civilian population in South Korea (n = 30,538), conducted from July 2008 to December 2011. The prevalence of strabismus and nystagmus were verified, and associated sociodemographic factors was evaluated. Results: The overall prevalence of strabismic disorder in participants over 3 years of age was $1.4{\pm}0.1%$ (95% confidence interval [CI] 1.3-1.6%; $1.5{\pm}0.1%$ in males, $1.3{\pm}0.1%$ in females). The prevalence of exodeviation (15 or more prism diopters), esodeviation (10 or more prism diopters), vertical deviation, and other complicated strabismus and nystagmus was 1.0%, 0.2%, 0.2%, 0.1% and 0.1% respectively. The prevalence was highest in the 6 to 15-year age group ($1.9{\pm}0.3%$), and lowest in the 40 to 49 years age group ($0.8{\pm}0.1%$) (p = 0.005). There were no statistically significant differences for gender, region, residential area, household income, educational level and occupation. Conclusions: This nation-wide epidemiologic study demonstrated that the prevalence of strabismus and nystagmus according to various sociodemographic factors in South Korea was not statistically significant except for age group. Further investigations are required based on more surveys to better recognize the etiologic or risk factors that may be related to strabismus and nystagmus.

Effect of Intense Regulated Pulse Light on Thickness of Tear Film Lipid Layer and Dry Eye Syndrome (조절펄스광선조사가 눈물막 지질층 두께 및 안구건조증에 미치는 효과)

  • Gil, Tae Young;Bae, Gi Hyun;Kwag, Joo Young;Hyun, Joo;Choi, Jin Seok;Pak, Kyu Hong;Chung, Sung Kun
    • Journal of The Korean Ophthalmological Society
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    • v.59 no.12
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    • pp.1103-1107
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    • 2018
  • Purpose: To evaluate the clinical effect of intense regulated pulse light (IRPL) and changes in tear film thickness in dry eye patients. Methods: A retrospective study was conducted on 25 patients with Meibomian gland dysfunction who had subjective dry eye discomfort and whose tear film break-up time (TBUT) was < 10 seconds. All patients were treated with IRPL three times on days 1, 15, and 45. TBUT, Schirmer 1 test results, cornea staining score with fluorescein, ocular surface disease index (OSDI), and lipid layer thickness were measured and compared before and after the procedure. Results: TBUT was significantly increased from $3.7{\pm}1.2s$ to $4.4{\pm}2.1s$ after IRPL (p = 0.03). Schirmer 1 test and cornea staining scores changed significantly (p < 0.01 and p = 0.01, respectively). OSDI also showed a statistically significant improvement from $39.5{\pm}17.5points$ to $30.4{\pm}18.7points$ (p = 0.01). However, no significant difference in lipid layer thickness was observed (p = 0.49). Conclusions: IRPL is an effective treatment modality to improve TBUT, Schirmer 1 test scores, cornea staining scores, and subjective dry eye symptoms.

PIERRE ROBIN SEQUENCE: A CASE REPORT AND REVIEW OF THE LITERATURE (Pierre Robin Sequence 환아의 증례보고)

  • Lee, Jung-Eun;Song, Je-Seon;Kim, Seong-Oh;Lee, Jae-Ho
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.5 no.2
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    • pp.92-95
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    • 2009
  • In 1923, Pierre Robin, a French stomatologist, first reported the association of micrognathia with glossoptosis. As more than 80% of all Pierre Robin cases accompanied with other syndrome such as Stickler syndrome, velocardiofacial syndrome, fetal alcohol syndrome, Treacher Collins syndrome, etc, it is called Pierre Robin sequence(PRS). PRS is described in the literature as a triad of anomalies characterized by micrognathia, glossoptosis and cleft palate. Clinically, the triad consists of airway obstruction and feeding difficulty, which are more frequent and severe in the neonatal period. In this case, a 14-month old boy with PRS was referred to the department of pediatric dentistry, Yonsei university dental hospital, who resolved airway obstruction by lateral positioning and feeding problem by percutaneous endocutaneous gastrotomy insertion. PRS is a developmental disorder as well as an anatomic obstructive disorder, therefore it should be dealt with by a multidisciplinary team.

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Two-Branch Classifier for Retinal Imaging Analysis (망막 영상 분석을 위한 두 갈래 분류기)

  • Oh, Young-tack;Park, Hyunjin
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.614-616
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    • 2021
  • The world faces difficulties in terms of eye care, including treatment, quality of prevention, vision rehabilitation services, and scarcity of trained eye care experts. However, it is difficult to develop a method for classifying various ocular diseases because the existing dataset for retinal image disclosure does not consist of various diseases found in clinical practice. We propose a method for classifying ocular diseases using the Retinal Fundus Multi-disease Image Dataset (RFMiD), a dataset published in the ISBI-2021 challenge. Our goal is to develop a robust and generalizable model for screening retinal images into normal and abnormal categories. The performance of the proposed model shows a value of 0.9782 for the test dataset as an area under the curve (AUC) score.

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A Study on the Phoria of Korean Male and Female Adults (한국인 성인 남녀의 사위에 관한 연구)

  • Sung, Duk Yong
    • Journal of Korean Ophthalmic Optics Society
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    • v.6 no.1
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    • pp.59-63
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    • 2001
  • Once refractive error of the eye was fully corrected. Polarization Test was used to investigate binocular vision function. As the results of phoria measurement of Korean adults for 53males and 59 females, orthophoria in 27.68%, esophoria in 12.50%, exophoria in 48.21%, verical phoria in 3.75%, esophoria(+verical phoria) in 2.68%, and exophoria(+vertical phoria) in 5.36%, respectively. Horizontal phoria is below $3{\Delta}$ mostly and verical phoria is below $1{\Delta}$.

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A Survey of Ophthalmic Diseases in Korean Jindo dogs (한국 진도견의 안과질환에 관한 연구)

  • 서강문;장광호;정종태;연성찬;이계웅;남치주
    • Journal of Veterinary Clinics
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    • v.18 no.3
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    • pp.215-225
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    • 2001
  • This study presented the results of ophthalmic examinations performed on 545 Korean Jindo dogs. The most prevalent ocular variation within normal limits was hyoid vessel remnant (12.7%) and prominence of lens suture was also noticed (1.7%). The most common ocular diseases were retinal scars (6.8%), focal cataract (4.6%) and persistent pupillary membrane (4.2%). Inherited ocular diseases found in this study were persistent pupillary membrane (4.2%), persistent hyperplastic primary vitreous (0.6%), retinal dysplasia (0.6%), entropion (0.4%) and progressive retinal atrophy (0.4%). The prevalence of ocular diseases was higher in Male than in Female and proportionately higher in the older dogs. The most prevalence was shown in white coat color dogs. The fundus color changes according to the age was not related in coat colors and shown same pattern.

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