• Title/Summary/Keyword: 악성 복수

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Ascitic Fluid Analysis for the Differentiation of Malignancy-Related and Nonmalignant Ascites (악성 복수와 비악성 복수의 감별을 위한 복수액 분석)

  • Lee, Eun-Young;Kim, Byeoung-Deok;Choi, Jae-Hyuk;Lee, Sang-Yeop;Ryu, Hun-Mo;Lee, Kyung-Hee;Hyun, Myung-Soo
    • Journal of Yeungnam Medical Science
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    • v.16 no.1
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    • pp.76-84
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    • 1999
  • The differentiation between malignancy-related ascites(MRA) and non-malignant ascites (NMA) is important for further diagnostic and therapeutic purposes. Although many parameters were investigated, none has provided a complete distinction between MRA and NMA. We investigated several ascitic fluid parameters to determine the differential power, and to differentiate malignant-related from nonmalignant-related ascites with a sequence of sensitive parameters followed by specific parameters. For the present study, 80 patients with ascites were divided into two groups: MRA and NMA, The MRA group was consisted of 27 patients with proven malignancy by image study, biopsy, and follow up: 21 of these patients had peritoneal carcinomatosis, but the remaining 6 showed no evidence of peritoneal carcinomatosis. The NMA group was consisted of 53 patients with no evidence of malignancy: among these patients, one had SLE, and others had liver cirrhosis, The samples of blood and ascites were obtained simultaneously, and then the levels of ascites cholesterol, CEA. protein and LDH, cytology, albumin gradient, ascites/serum concen-tration ratios of LDH(LDH A/S), and ascites/serum concentration ratios of protein(protein A/S) were measured. Applying cut-off limits for determined parameters, we estimated the diagnostic efficacy of each parameter, Among the eight parameters investigated, ascites fluid cholesterol yielded the best sensitive value of 93%(cut-off value 30mg/dl), and cytologic examination and the protein A/S(cut-off value 0.5) showed the most specific value of 100% and 96%, respectively. Based on the above results, the diagnostic sequence with cholesterol as a sensitive parameter followed by the combination of cytologic examination and protein A/S as specific parameters, was tested in 80 patients. This diagnostic sequence identified 81.5% of patients with malignancy, and all patients with peritoneal carcinomatosis were classified as malignancy-related ascites. In spite of many limitations, this proposed diagnostic sequence may permit a cost-effective and simple differentiation of malignancy-related ascites from nonmalignant ascites.

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Diagnostic Significance of Total Lactate Dehydrogenase(LD) and LD Isoenzyme Measurement in the Body Fluids (체강액에서 총 Lactate dehydrogenase 및 Lactate dehydrogenase 동위효소 측정의 진단학적 의의)

  • Jeon, Chang-Ho;Bae, Eun-Kyung;Hong, Seok-Il;Kim, Chung-Sook;Lee, Young-Hyun
    • Journal of Yeungnam Medical Science
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    • v.3 no.1
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    • pp.193-199
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    • 1986
  • Body fluid Lactate dehydrogenase and its isoenzyme measurement was performed in 132 patients: 8 cases with peritonitis, 21 cases with malignant ascites, 43 cases with liver cirrhosis, 48 cases with tuberculous pleuritis, 12 cases with malignant pleural effusion respectively. Body fluid protein and glucose contents, red blood cell counts, white blood cell counts, cytologic examination were also performed as a comparative study. The results were as follows: 1. Measurement of total LD and protein amount could differentiate between transudate and exudate in the ascitic fluids. 2. In the malignant exudate of ascites and pleural fluid, the activity of LD2 isoenzyme was statistically increased compared with that of inflammatory exudate and the activity of LD4 isoenzyme was also increased compared with that of serum(P<0.05). 3. The inflammatory exudate of pleural fluid and ascites demonstrated the increase of LD5 isoenzyme activity stastistically compared with that of serum and malignant exudate(P<0.05). 4. A difference of total LD activity between malignant ascites and inflammatory ascites was significant statistically, while this was not observed in the pleural exudate. 5. Total LD and LD5 isoenzyme activity didn't correlated with the number of white blood cells in the exudate.

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Intraperitoneal Cisplatin Chemotherapy in A Canine Ovarian Cancer with Peritoneal Metastasis (복강전이가 동반된 개 악성 난소암의 cisplatin 치료)

  • Seo, Kyoung-Won;Lee, Jong-Bok;Hong, Su-Ji;Oh, Ye-In;Lee, Su-Hyung;Youn, Hwa-Young;Jang, Goo
    • Journal of Veterinary Clinics
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    • v.28 no.6
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    • pp.598-602
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    • 2011
  • A 4-year-old female Shih-tzu dog weighing 5.1 kg was referred with abdominal distension and diagnosed as cystic papillary adenocarcinoma with metastasis to serosal surface of abdomen by biopsy. Intraperitoneal chemotherapy with cisplatin (50 $mg/m^2$) diluted in normal saline (250 $ml/m^2$) was initiated following removal of ascites one month after ovariohysterectomy (OHE). Clinical response was great and had no side effects during the chemotherapy period (3 relapses, 33 months after diagnosis). However, pleural effusion occurred with ascites and renal failure at the end of treatment. Eleven treatments of cisplatin were performed during 35 months after diagnosis. Intraperitoneal cisplatin instillation has been effective to control malignant ascites and pleural effusion in ovarian cancers and could be a reasonable palliative treatment. This is the first case report describing intraperitoneal cisplatin chemotherapy in metastatic ovarian cyst papillary adenocarcinoma in Korea.

The Propagation Dynamics of Multiple Internet Worms (복수 인터넷 웜의 확산 방식 연구)

  • Shin, Weon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.19 no.12
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    • pp.2858-2864
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    • 2015
  • Internet worms have been the major Internet threats may disclose important information and can bring about faults of computer systems, which spread with the fastest speed among malicious codes. Simultaneously spreading multiple worms and its variants are revealing the limitation of conventional responses based on single worms. In order to defend them effectively, it is necessary to study how multiple worms propagate and what factors affect worm spreading. In this paper, we improve the existed single worm spreading models and try to describe the correct spreads of multiple worms. Thus we analyze the spreading effects of multiple worms and its variants by various experiments.

Analysis of Effect and Prognostic Factors Associated with Catheter Intervention on Ascites in Terminal Cancer Patient (복수가 있는 말기 암환자에서 복수 배액관 시술의 효과와 예후요인 분석)

  • Jang, Mungsun;Kim, Chul-Min;Yoon, Johi;Nah, Jung-Ran;Chang, Seung-Nam;Kim, Myung Ok;Lee, Ja Young
    • Journal of Hospice and Palliative Care
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    • v.19 no.4
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    • pp.303-309
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    • 2016
  • Purpose: Malignant ascites is a common complication in terminal cancer patients. Less-invasive pigtail catheter insertion is the most frequent procedure in patients who need repeated ascites drainage. This study investigated effects and adverse events associated with catheter insertion for ascites drainage and evaluated prognostic outcomes. Methods: We reviewed medical records between 2010 and 2013 of hospice and palliative care institutions in Seoul, South Korea. Among 2,608 inpatients, 67 patients received ascites pigtail catheter drainage. We reviewed demographic data, palliative performance scale, laboratory data, duration of catheter insertion, prevalence and type of complications, use and duration of antibiotics, and survival time. Univariate and multivariate Cox regression models were used to evaluate prognostic outcomes related with catheter insertion. Results: Ascites drainage was performed most commonly in hepatobiliary and gastric cancer patients. Ascites symptoms improved in 55 patients after the catheter drainage. Adverse events included pain (19.4%), leakage (14.9%), disconnection (7.5%), catheter occlusion (6%) and fever (4.5%). In Cox regression analysis, survival time from the catheter insertion was significantly associated with Palliative Performance Scale (PPS) (HR 0.73; P value 0.045) and serum sodium level (HR 2.77; P value 0.003) in a multivariate model. Conclusion: Patients' PPS and serum sodium level should be considered before making a decision of pigtail catheter insertion.

Lymphangioleiomyomatosis with Bilateral Chylothorax -1 case report- (양측 유미흉을 동반한 림프관평활근종증)

  • 김시욱;최재성;나명훈;임승평;이영;유재현
    • Journal of Chest Surgery
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    • v.37 no.12
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    • pp.1029-1031
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    • 2004
  • We had expierienced pulmonary lymphangioleiomyomatosis(LAM) with bilateral chylothorax and chylous ascites. A twenty-one-year-old lass with chief complaint of abdominal pain was admitted through the emergency room. She received emergent pelvicoscopic surgery for the rupture of the right corpus luteum. We aspirated 1000ml of the uncoagulated blood. The bleeding point was cautherized electrically. LAM was diagnosed with tissue from the retroperitoneum. Chylous ascites and bilateral chylothorax were occurred despite of various treatments. On thoracotomy, bullous changed lung and lymphatic leakage from visceral and parietal pleura were observed. She died of respiratory insufficiency and general weakness after 6 months from admission.

A Study of Bare Metal Hypervisor Based Hacking And Malicious Code Protect Technology For Secure Cloud Service (안전한 클라우드 서비스를 위한 Bare Metal Hypervisor기반 해킹 및 악성코드 차단 기술에 대한 연구)

  • Jin, Byung-wook;Kim, Hyung-Min;Choi, Do-Hyun;Jun, Mun-Seok
    • Proceedings of the Korea Information Processing Society Conference
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    • 2012.04a
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    • pp.753-755
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    • 2012
  • 최근 클라우드 서비스의 가상화 기술이 급부상 하면서 이슈화되고 있는 문제는 안전성과 신뢰성이다. 클라우드 서비스의 가상화 계층의 손상은 모든 호스트 업무의 손상을 가져올 수 있기 때문에 복수의 가상 운영체제가 구동될 수 있는 환경을 제공하는 하이퍼바이저는 해커들에 의해 공격 대상이 될 수 있다. 본 논문에서는 클라우드 서비스를 위한 대표적인 기술 중 보안이 취약하다고 분석되는 베어 메탈 기반의 하이퍼바이저의 해킹 및 악성코드에 대한 차단 기법을 제안한다.

Transmission Performance of MANET under Multiple Blackhole Attacks (다중 블랙홀 공격이 있는 MANET의 전송성능)

  • Kim, Young-Dong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.783-786
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    • 2015
  • Hole attack, which is disturbed transmission function through change of routing information, can cause critical results for MANET as non-infrastructure network. Backhole attack, as a typical hole attack, is one malicious attack which is disabled network transmission function by assumption of transmission data through modification of routing information. It is very important to evaluate transmission performance caused by blackhole attack, because transmission performance of MANET is affective with blackhole attack. In this paper, transmission performance is analyzed with MANET under multiple blackhole attacks caused multiple blackhole nodes. Computer simulation based on NS-2 is used as analysis tool and voice traffic is considered ad application service on MANET.

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EFFECT OF RED GINSENG POWDER ON LIPOLYTIC AND ANOREXIGENIC FACTOR (TOXOHORMONE-L) FROM CANCEROUS ASCITES FLUID (암의 복수액에 존재하는 지방분해 및 식욕감퇴 인자에 미치는 고려인삼의 영향)

  • Okuda Hiromichi;Masuno Hiroshi;Lee Song Jae
    • Proceedings of the Ginseng society Conference
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    • 1984.09a
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    • pp.145-152
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    • 1984
  • Toxohormone-L (THL) elicited fatty acid release from rat epididymal adipose tissue, which is present in cancerous ascites fluids. In this study, the effect of ginseng powder on lipolysis induced by Toxohormane-L, and ACTH was studied. Korean ginseng selectively inhibited Toxohormone-L induced lipolysis, but did not inhibit ACTH-induced lipolysis.

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The Management of Malignant Ascites in Terminal Cancer Patients (말기 암환자에서 악성 복수의 치료)

  • Kim, Sun-Hyun;Yeom, Chang-Hwan
    • Journal of Hospice and Palliative Care
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    • v.11 no.3
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    • pp.131-135
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    • 2008
  • The management of malignant ascites can be problematic for physicians and patients. The mass effect of ascites can cause symptoms of painful abdominal distention, nausea, vomiting, and bowel obstruction. Also patients often complain of shortness of breath and lower extremity edema. These symptoms not only are distressing, but also adversely affect quality of life in terminal cancer patients. We will introduce you how to treat ascites based on our cases.

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