In this study, a formula (EJ-F101) was prepared to develop a raw material for acne-prone skin improvement using wheat germ extract, and a clinical trial cream was prepared and clinical trials were conducted. As a result of the analysis, when comparing before and after using the product, both the test group and the control group showed significant improvement effects in terms of open comedones, occluded comedones, papules, sebum and oil content in the facial region at 4 weeks after product use, compared to the control group in the test group which showed a more significant improvement effect. As a result of the survey on the efficacy of the product, most items showed higher positive answers in the test product compared to the control product four weeks after the use of the product, and about 43-81% of the study subjects answered positively in the test product, except for the "open surface" item. In addition, for all items related to the usability of the product, about 14-86% of the test group and 38-90% of the control group answered positively at the time point 4 weeks after using the product. As a result of skin safety evaluation, no adverse skin reactions were observed in all subjects of this study. Based on the above results, it is considered that the cream using wheat germ extract is suitable for use on acne-prone skin(non comedogenicity).
We have studied crystallographic and magnetic properties of $NdFe_{10.7}Ti_ {1.2}Mo_{0.1}$ by Mossbauer spectroscopy, X-ray diffraction and vibrating sample magnetometer (VSM). The alloys were prepared by arc-melting under an argon atmosphere. The $NdFe_{10.7}Ti_{1.2}Mo_{0.1}$ has pure a single phase, whereas $NdFe_{10.7}Ti_{1.3}$ contains some $\alpha$-Fe, conformed with X-ray diffractometry and Mossbauer measurements. The $NdFe_{10.7}Ti_ {1.2}Mo_{0.1}$ has a $ThMn_{12}-type$ tetragonal structure with $a_0=8.637{\AA}$ and $c_0=4.807{\AA}$. The Curie temperature ($T_c$) is 600 K from the result of Mossbauer measurement performed at various temperatures ranging from 13 to 800 K. Each spectrum of below $T_c$ is fitted with five subspectra of Fe sites in the structure ($8i_1, 8i_2, 8j_2, 8j_1, 8f$). The area fractions of the subspectra at room temperature are 12.3%, 14.0%, 21.0% 11.8%, 40.9%, respectively. Magnetic hyperfine fields for the Fe sites decrease in the order, $H_{hf}(8i)>H_{hf}(8j)>H_{hf}(8f)$. The abrupt changes in the magnetic hyperfine field, an magnetic moment observed at about 160 K in $NdFe_ {10.7} Ti_{1.2}Mo_{0.1}$ are attributed to spin reorientations. The average hyperfine field of the $NdFe_{10.7}Ti_{1.2}Mo_{0.1}$ shows a temperature dependence of $[H_{hf}(T)-H_{hf}(0)]/H_{hf}(0)=-0.34(T/T_C)^{3/2}-0.14(T/T_C)^{5/2}$ for $T/T_c<0.7$, indicative of spin wave excitation. The Debye temperatures of $NdFe_{10.7}Ti_{1.2}Mo_{0.1}$ is found to be Θ=340$\pm$5 K.
Seo, Yoon-Jeong;Oh, Gye-Jeong;Lee, Hyo-Il;Shin, Yoo-Jin;Kim, Hong-Joo;Park, Sang-Won
The Journal of Korean Academy of Prosthodontics
/
v.51
no.4
/
pp.261-268
/
2013
Purpose: The purpose of this study was to investigate the effect of geometrically different wax pattern shapes and sizes on the castability of Grade2 Cp-Ti (commercially pure titanium). Materials and methods: Total of 40 mesh wax pattern ($61mm{\times}24mm$, 207 grids), ($61mm{\times}17mm$, 138 grids) was cast in this experiment. Depending on the geometrical shape of the wax pattern, 8 groups was organized; Flat, Semicircular, Horse-shoe and V-shape, each consisting 5 samples. Runner-bar sprue was used in all patterns. The number of completely cast grid in wax pattern served as a measure for the castability of comercially pure titanium. Results: The mean value of square count in each group was as followed; 133.20 squares in group SS (96.52%), 132.40 squares in group SH (95.94%), 132.00 squares in group SF (95.65%), 127.60 squares in SV (91.43%), 198.60 squares in group LF (95.94%), 197.80 squares in group LV (95.56%), 196.40 squares in group LS (94.88%), and 188.00 squares in group LH (90.82%). Conclusion: Within the limitations of this study the results indicate that there were no sttistically significant difference in castability of titanium regarding wax pattern shape (P>.05). However, Small size wax patterns were showing the noticeable castability more than Large size pattern.
Journal of the korean academy of Pediatric Dentistry
/
v.30
no.3
/
pp.431-438
/
2003
This study investigates pulp chamber temperature rise during composite resin polymerization by plasma arc(Group III : Flipo 3 sec, Group IV : Flipo 5 sec) and LED curing units(Group V : Lux-O-Max, 40 sec) as well as conventional halogen lamp curing units(Group I : VIP mode3, 20 sec, Group II : VIP mode6, 20 sec). The results are as follows : 1. All of the investigated pulp chamber temperature rises are lower than the boundary temperature could result in irreversible damage to the pulpal tissue ($5.5^{\circ}C$). 2. In the group II, it is found the significantly higher pulp chamber temperature rise than any other groups(p<0.05). 3. In the group of composite resin light-cured with VIP, it is found the significantly higher pulp chamber temperature rise in the group II than group I(p<0.05). 4. In the group of composite resin light-cured with Flipo, it is found the significantly higher pulp chamber temperature rise in the group IV than group III (p<0.05). 5. In the case of comparing VIP and Flipo, group II is significantly higher pulp chamber temperature rise than group III, IV(p<0.05), and group IV is significantly higher pulp chamber temperature rise than group I(p<0.05), and it does not significantly differ between group I and III. 6. In the group of composite resin light-cured with Lux-O-Max, it is found the significantly lower pulp chamber temperature rise than any other groups (p<0.05).
Southeastern Korean Peninsula has undergone the polyphase deformations according to the changes of regional tectonic settings during the Cenozoic. Through analyses of more than 600 fault-slip data gathered in the study area, five tectonic events are revealed as the followings: (I) NW-SE transtension, (II) NW-SE transpression, (III) NE-SW pure or radial extension, (IV) NNE-SSW transpression, (V) NE or ENE-WSW transpression. Event I was induced by the pull-apart type extension of the East Sea during 24-16 Ma, which resulted in the NW-SE extension of the Tertiary Basins in SE Korea. Event II was resulted from the collision of SW Japan and Izu-Bonnin Arc (or Kuroshio Paleoland) on the Philippine Sea Plate at ${\sim}$ 15 Ma, which stopped the extension of the Tertiary Basins and originated the uplift of fault blocks in and around SE Korean Peninsula. It was continued until ${\sim}$ 10 Ma. Event III is interpreted as the post-tectonic event after the block-uplifts due to the event II, which indicates a temporal lull in activity of the Philippine Sea Plate since 10 Ma. Event IV was originated from the resumption in activity of the Philippine Sea Plate which was restarted to move toward north at ${\sim}$ 6 Ma. The event made the EW compressional structures behind SW Japan as well as in the Korea Straits, and thus the block-uplifts in SE Korea was resumed again. Lastly, event V was resulted from the gradual decrease in influence of the Philippine Sea Plate and the cooperative compression due to the subduction of the Pacific Sea Plate and the collision of the Indian Plate since 5-3.5 Ma, which generated the NS compressional structures in the offshore along the eastern coast of the Korean Peninsula and thrust up the fault-blocks toward west. This event is continuing so far, and thus is making the active faultings resulting in the present earthquakes of the Korean Peninsula.
The southeastern Korean Peninsula has experienced crustal multi-deformations according to changes of global tectonic setting during the Cenozoic. Characteristic features of the crustal deformations in relation to major Cenozoic tectonic events are summarized as follows. (1) Collision of Indian and Eurasian continents and abrupt change of movement direction of the Pacific plate (50${\sim}$43 Ma): The collision of Indian and Eurasian continents caused the eastward extrusion of East Asia block as a trench-rollback, and then the movement direction of the Pacific plate was abruptly changed from NNW to WNW. As a result, the strong suction-force along the plate boundary produced a tensional stress field trending EW or WNW-ESE in southeastern Korea, which resultantly induced the passive intrusion of NS or NNE trending mafic dike swarm. (2) Opening of the East Sea (25${\sim}$16 Ma): The NS or NNW-SSE trending opening of the East Sea generated a dextral shear stress regime trending NNW-SSE along the eastern coast line of the Korean Peninsula. As a result, pull-apart basins were developed in right bending and overstepping parts along major dextral strike slip faults trending NNW-SSE in southeastern Korea. The basins can be divided into two types on the basis of geometry and kinematics: Parallelogram-shaped basin (rhombochasm) and wedged-shaped basin (sphenochasm), respectively. In those times, the basins and adjacent basement blocks experienced clockwise rotation and northwestward tilting contemporaneously, and the basins often experienced a kind of propagating rifting from NE toward SE. At about 17Ma, the Yonil Tectonic Line, which is the westernmost border fault of the Miocene crustal deformation in southeastern Korea, began to move as a major dextral strike slip fault. (3) Clockwise rotation of southeastern Japan Island (about 15 Ma): The collision of the Izu-Bonin Arc and southeastern Japan Island, as a result of northward movement of the Philippine sea-plate, induced the clockwise rotation of southeastern Japan Island. The event caused the NW-SE compression in the Korea Strait as a tectonic inversion, which resultantly tenninated the basin extension and caused local counterclockwise rotation of blocks in southeastern Korea. (4) E-W compression in the East Asia (after about 5 Ma): Decreasing subduction angle of the Pacific plate and eastward movement of the Amurian plate have constructed the-top-to-west thrusts and become a major cause for earthquakes in southeastern Korea until the present time.
Background: We tested the technical feasibility of fetal cardiac bypass and collected baseline data on the fetal hemodynamics and placental functions related to the cardiopulmonary bypass in the fetal lamb model. Material and Method: Eleven fetuses at 120 to 150 days of gestation were subjected to bypass via trans-sternal approach with a 12 G pulmonary arterial cannula and 14 to 18 F venous cannula for 30 minutes. All ewes received general anesthesia with ketamine. In all the fetuses, no anesthetic agents were used except muscle relaxant. Eight served as a group in which placenta was excluded from the extracorporeal circulation by clamping the umbilical cord during the bypass(the oxygenator group) and in the remaining three, the placenta worked as the only source of oxygen supply(the placenta group). Observations were made every 10 minute during a 30-minute bypass and 30-minute post bypass period. No prostaglandin inhibitors were used both in ewes and in fetuses. Result: Weights of the fetuses ranged from 1.9 to 5.2 kg. In the oxygenator group, means of arterial pressure, PaO2, atrial pressure, heart rate, and bypass flow rate ranged 69.8 to 82.6 mmHg, 201.7 to 220.9 mmHg, 4.1 to 4.3 mmHg, 169 to 182/min, and 140.3 to 164.0 ml/kg/min, respectively during bypass, but rapid deterioration of the fetal cardiac functions and the placental gas exchange was observed after the cessation of bypass. In the placenta group, means of arterial pressure decreased from 44.7 to 14.4 mmHg and means of PaCO2 increased from 61.9 to 129.6 mmHg during bypass. Flow rate was suboptimal(74.3 to 97.0 ml/kg/min) during bypass. All hearts fibrillated immediately after the discontinuation of bypass. Conclusion: In this study, the technical feasibility of fetal cardiopulmonary bypass was confirmed in the fetal lamb model. However, further studies with modifications of the bypass including an addition of prostaglandin inhibitor, an application of the total spinal anesthesia on the fetus, a creation of more concise bypass circuit, and a use of active pump are mandatory to improve the outcome.
Journal of the korean academy of Pediatric Dentistry
/
v.31
no.1
/
pp.66-78
/
2004
The objective of this study was to apply the vibration technique to reduce the viscosity of bonding adhesives and thereby compare the bond strength and resin penetration in enamel and dentin achieved with those gained using the conventional technique and vibration technique. For enamel specimens, thirty teeth were sectioned mesio-distally. Sectioned two parts were assigned to same adhesive system but different treatment(vibration vs. non-vibration). Each specimen was embedded in 1-inch inner diameter PVC pipe with a acrylic resin. The buccal and lingual surfaces were placed so that the tooth and the embedding medium were at the same level. The samples were subsequently polished silicon carbide abrasive papers. Each adhesive system was applied according to its manufacture's instruction. Vibration groups were additionally vibrated for 15 seconds before curing. For dentin specimen, except removing the coronal part and placing occlusal surface at the mold level, the remaining procedures were same as enamel specimen. Resin composite(Z250. 3M. U.S.A.) was condensed on to the prepared surface in two increments using a mold kit(Ultradent Inc., U.S.A.). Each increments was light cured for 40 seconds. After 24 hours in tap water at room temperature, the specimens were thermocycled for 1000cycles. Shear bond strengths were measured with a universal testing machine(Instron 4465, England). To investigate infiltration patterns of adhesive materials, the surface of specimens was examined with scanning electron microscope. The results were as follows: 1. In enamel the mean values of shear bond strengths in vibration groups(group 2, 4, 6) were greater than those of non-vibration group(group 1, 3, 5). The differences were statistically significant except AQ bond group. 2. In dentin, the mean values of shear bond strengths in vibration groups(group 2, 4, 6) were greater than those of non-vibration groups(group 1, 3, 5). But the differences were not statistically significant except One-Up Bond F group. 3. The vibration group showed more mineral loss in enamel and longer resin tag and greater number of lateral branches in dentin under SEM examination.
Akram, M.;Park, J. H.;Ryu, M. S.;Shin, K.H.;Ryu, K. S.
Journal of Animal Science and Technology
/
v.45
no.3
/
pp.369-376
/
2003
This experiment was conducted to investigate the influence of different levels of metabolizable energy (ME) and crude protein (CP) on post-molt performance and egg quality of spent laying hens. Four hundred and thirty two, ISA Brown hens at sixty six weeks of age after molt induction were fed six experimental diets containing three ME (2,750, 2,800, 2,850 kcal/kg) with two CP (15, 17%) levels in a factorial design. The influence of ME and CP were evaluated on egg production, egg weight and feed intake throughout 24 weeks of production. Egg mass and feed conversion ratio (FCR) were measured during the experimental period. Haugh unit, yolk color and eggshell breaking strength were measured at 5%, 50%, peak, post peak and end stage of egg production. The hens fed 2800 kcal/kg diet along with 15% CP recorded the highest outcome of egg production (P<0.05). The egg weight has been shown to increase with hens receiving 2,800 kcal/kg ME. Daily egg mass tended to increase in hens fed with 15% CP and 2,800 kcal/kg ME. Feed intake decreased significantly with the level of ME and CP in the diet increased (P<0.05). Yolk color was improved significantly in eggs laid by the hens receiving 17% CP than 15% diet. It also tended to be higher in 17% CP with 2,800 or 2,850 kcal/kg ME diet treatments. Egg shell breaking strength increased with hens receiving diets of 15% CP and 2,800 kcal/kg. From this experiment it can be concluded that the ME level of 2,800 kcal/kg coupled with 15% CP could be used to achieve the higher egg production and better eggshell strength in induced molting hens.
Nitrogen ion implantation and ion plating techniques were applied for improvement of the wear resistance of metallic implant materials. In this work, the wear dissolution behaviour of a nitrogen ion implanted super stainless steel (S.S.S, 22Cr-20Ni-6Mo-0.25N) was compared with those of S.S.S, 316L SS and TiN coated 316L SS. The amounts of Cr and Ni ions worn-out from the specimens were Investigated using an electrothermal atomic absorption spectrometry. Furthermore, the Ti(Grade 2) disks were coated with TiN, ZrN and TiCN by use of low temperature arc vapor deposition and the wear resistance of the coating layers was compared with that of titanium. The chemical compositions of the nitrogen ion implanted and nitride coated layers were examined with a scanting auger electron spectroscopy. It wat observed that the metal ions released from the nitrogen ion implanted S.S.S surface were significantly reduced. From the results obtained, it was shown that the nitrogen ion implanted zone obtained with 100 KeV ion energy was easily removed within 200,000 revolutions from a wear dissolution testing under a similar load condition when applied to artificial hip joint. The remarkable improvement in wear resistance weir confirmed by the nitrides coated Ti materials and the wear properties differ greatly according to the chemical composition of the coating layers. for specimens with the same coating thickness of about 3$\mu\textrm{m}$, TiCN coated Ti showed the highest wear resistance. However, after removing the coating layers, the wear rates of all nitrides coated Ti reverted to their normal rates of below 10,000 revolutions from Ti-disk-on-disk wear testing under the same load condition. From the results obtained, it is suggested that the insufficient depth of the 100 Kel N$\^$+/ ion implanted zone and of the nitrides coated layers of 3$\mu\textrm{m}$ are subject to restriction when used as frictional parts of load bearing implants.
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