• Journal of the Korea Convergence Society
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• v.8 no.8
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• pp.137-145
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• 2017

The purposed of this study was to identify cardiocerebrovascular disease risk assessment and the factors that affect cardiocerebrovascular disease risk. The subjects of this study were 1340 middle age women worker in one shipyard. This study was base on worker health check up data. Data were analyzed using SPSS18.0 program. "healthy group" were 1078(80.4%), "low risk group" were 45(3.4%), "moderate risk group" were 150(11.2%), "high risk group" were 67(5.0%). Age, HDL, LDL, smoking, family history of stroke, hypertension were the factors that affected the risk cardiocerebrovascular disease. Results of this study can be used as fundamental data for developing cardiocerebrovascular disease preventive program in middle aged women.

• Journal of Advanced Navigation Technology
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• v.18 no.6
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• pp.582-587
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• 2014

This study have researched on feasibility of bioelectrical impedance analysis (BIA, which is simple useful evaluation tool for predictive factor of cardiovascular disease) to patients who have to travel along the sea for a long-period time and have difficulty in visiting medical institutions. We studied on the basis of total cholesterol value, which is nowadays widely used tool for predictive factor of cardiovascular disease, and also studied its association with BIA value via statistical analysis. Our result showed correlation with fat thickness of individual sites, and especially, fat thickness of left thigh showed high relation with total cholesterol value. This result shows that people who are in travel of long-period of time at sea are feasible of using BIA to evaluate changes of left thigh fat thickness as predictive factor for cardiovascular disease. Due to lack of advanced researches further studies should be done. And based on special circumstances in sea, more studies should be done to validity concerning this circumstances and accuracy of this evaluation tool.

• Korean journal of health promotion
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• v.17 no.2
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• pp.109-118
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• 2017

Background: Abdominal obesity as measured by waist-to-height ratio (WHtR) may have stronger and inverse associations with cardiovascular (CV) health than overall obesity as measured by body mass index (BMI). However, there was some challenges for controversies. We aimed to examine the associations of WHtR and BMI with CV health among Korean children using data of the 2010-2012 Korea National Health and Nutrition Examination Survey. Methods: A cross-sectional study was conducted with the sample of 2,363 children by analyzing by gender and two-age groups (10-12 and 13-18 years). Overall obesity was categorized into 3 groups by BMI percentile: non-overweight (<85), overweight (${\geq}85$), and obesity groups (${\geq}95$). Abdominal obesity was categorized into 2 groups by WHtR: normal (<0.5) and abdominal obesity groups (${\geq}0.5$). The CV health score was defined as a z-score by calculating the sum of 7 CV factors. Results: The overweight/obesity groups had significantly lower CV health scores than the normal group (P<0.05) in boys and girls aged either 10-12 years or 13-18 years after adjusting for covariates. The abdominal obesity group also showed significantly lower CV health scores than the normal group (P<0.05) in all the groups; this significant association remained significant in boys aged 13-18 years even after further adjusting for BMI category (P<0.01). Conclusions: Among boys aged 13-18 years, abdominal obesity as measured by WHtR was significantly and inversely associated with CV health, independent of BMI category. Therefore, it should be considered to assess the level of abdominal obesity as a measure of CV health in late adolescent boys.

• Korean Journal of Psychosomatic Medicine
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• v.19 no.2
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• pp.57-65
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• 2011

There are numerous drug interactions related to many psychotropic and cardiovascular medications. Firstly, the principles in predicting drug interactions are discussed. Cytochrome P (CYP) 450 plays a significant role in the metabolism of these drugs that are substrates, inhibitors, or inducers of CYP450 enzymes. The two most significant enzymes are CYP2D6 and CYP3A4. The ability of psychotropic drugs to act as inhibitors for the enzymes may lead to altered efficacy or toxicity of co-administered cardiovascular agents as a substrate for the enzymes. The following is also a review of the known interactions between many commonly prescribed cardiovascular agents and psychotropic drugs. Most beta blockers are metabolized by CYP2D6, which may lead to drug toxicity when they use in combination with potent CYP2D6 inhibitors including bupropion, chlorpromazine, haloperidol, selective serotonin reuptake inhibitors, and quinidine. Concomitant administration of lithium with angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and diuretics may increase serum lithium concentrations and toxicity. Calcium channel blockers and cholesterol lowering agents are subject to interactions with potent inhibitors of CYP3A4, such as amiodarone, diltiazem, fluvoxamine, nefazodone, and verapamil. Prescribing antiarrhythmic drugs in conjunction with medications are known to prolong QT interval and/or inhibitors on a relevant CYP450 enzyme is generally not recommended, or needs watchful monitoring. Digoxin and warfarin also have warrant careful monitoring if co-administered with psychotropic drugs.

• Journal of Nutrition and Health
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• v.49 no.5
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• pp.304-312
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• 2016

Purpose: The purpose of the study was to investigate the association between food intakes and cardiovascular disease (CVD) risk factors in Korean women with type 2 diabetes mellitus (T2DM). Methods: The data were collected from the 2007~2012 Korea National Health and Nutrition Examination Survey (KNHANES). In this study, subjects were divided into two groups, the normal fasting glucose (NFG) group (n = 7,738) and the T2DM group (n = 225). Dietary intake was derived from the nutrition survey, which was collected by trained dietitians using 24-hour dietary recall through the face-to-face interview method in the sample person's home. Results: After adjustment for confounding factors, mean fruit (p = 0.0265), fruit and vegetable without kimchi (p = 0.0295), and fish (p = 0.0112) intakes were significantly lower in the T2DM group than in the NFG group. In the multiple logistic regression analysis, odds ratio (OR) for risk of high systolic blood pressure (${\geq}140mmHg$) was lower in the over the median compared to under the median for fruit intakes (OR; 0.657, 95% CI; 0.523~0.824). The OR for the risk of hypertriglyceridemia was lower in the over the median compared to under the median for fruit and vegetable without kimchi (OR; 0.828, 95% CI; 0.7111~0.963) and fish (OR; 0.783, 95% CI; 0.673~0.910) intakes. Conclusion: These results show that intakes of fruits, fish, and fruits and vegetables without kimchi have beneficial effects on CVD in Korean women with T2DM.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.27 no.1
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• pp.111-134
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• 2016

The purpose of this study is to investigate and compare the intellectual structure of cardiovascular research area in Korea and the United States. For the purpose of this study, a data set was collected; one journal Korean Circulation Journal is in Korea and two journals Circulation, and Circulation Research are in the United States. Based on the frequency of citation counts, 45 authors and 53 authors were selected for author co-citation analysis. By multidimensional scaling, clustering, and factor analyses, the results demonstrate that researchers in both countries commonly tend to work on several, rather than focus on certain sub-areas. In both countries, the core areas are revealed as 'cardiovascular disease treatment', 'cardiovascular disease diagnose', 'cardiovascular disease fundamentals', and 'cardiovascular disease preventives'. One of distinctive differences between two is that research in Korea is likely to focus on clinical medicines while research in the United States tends to be on fundamental medicines. While the area of 'Disorders of Rhythm' is revealed in Korea, 'Pharmacology of the Cardiovascular System' area is found in the United States. In addition, the sub-areas of fundamental medicines such as 'Epidemiology of Cardiovascular Disease', 'Biology', 'Biochemistry', 'Physiology' are revealed distinctively in the United States.

• The Journal of the Korea Contents Association
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• v.11 no.5
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• pp.308-316
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• 2011

Familial concordance of vascular risk factors is well understood and there are many studies about inter-spouse concordance of the risk factors for coronary heart disease. However, there are no studies for inter-spousal relation of the risk factors in cerebrovascular disease patients. We analysed inter-spouse correlation of cerebrovascular risk factors in patients admitted our hospital due to stroke and their spouses. There was statistically significant inter-spouse concordance in the presence of hypertension(p=0.025) and carotid IMT(r=0.479, p=0.001). However, the further age-adjusted analysis revealed no significant result. Differently from the results of previous studie,, the present study shows no significant spousal concordance. Althought there are tendencies of spousal concordance in some risk factors, the age is major determinant.

• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.342-348
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• 2004

암은 심장질환에 의한 사망을 넘어서, 전 세계적으로 가장 중요한 사망원인이 되고 있으며, 우리나라와 같은 개발도상국에서도 생활 양식의 변화와 더불어, 암 이환율 및 사망률이 급격히 증가하고 있다. Table 1은 주요질병사망 원인의 변천을 보여주고 있으며, 1990년 암사망은 10만명당 105.2명에서 2000년 123.5명으로 뇌혈관 및 심혈관질환에 의한 사망을 앞지르고 있다.(중략)

• The Monthly Diabetes
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• s.188
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• pp.23-25
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• 2005

복부비만(내장지방 비만)은 인슐린 저항성과 밀접한 관련이 있으며 임상에서는 대사증후군의 형태로 나타나고, 제2형 당뇨병과 심혈관질환의 주요 위험요인으로 알려져 있다. 유전적 요인, 운동부족, 섭취량 과다, 고지방 고단순당식 등이 주요 원인이며, 치료는 원인을 찾아 이를 해결하고 동반질환이나 위험요인을 치료하며 식사요법과 운동을 병행하여 체중을 줄이고 필요한 경우 약물을 사용하는 것이다.

• 대한예방의학회:학술대회논문집
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• 2004.10a
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• pp.51.3-52
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• 2004