• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.5
• /
• pp.1191-1194
• /
• 2005

The aim of this study was to investigate the change of Heart Rate Variability(HRV) that mild cold stimulus on the forehead of healthy men induces. 34 healthy male subjects participated in the experiments. On the first test series, 15 subjects were applied to the mild cold stimulus by the devise for cold stimulation. In the second test series, 10 subjects With heat Syndrome and 5 subjects With cold Syndrome were applied to the mild cold Stimulus. Aa a additional test, 4 subjects with cold syndrome were applied to the warm stimulus in the last test series. We analyzed the HRV through measuring electrocardiogram.(ECG). The result of this study is comparatively clear. In the first test series, mild cold stimulus made parasympathetic nervous system be activated. In the second test series, mild cold stimulus made parasympathetic nervous system be activated both in subjects with heat syndrome and subjects with cold syndrome, and heat syndrome shows more active parasympathetic nervous system rather than cold syndrome subjects do. In the last test series, 2 subjects with cold syndrome respond the mild cold stimulus. That means warm stimulus of cold condition subjects made parasympathetic nervous system active in 2 of 4 subjects. We found out that mild cold stimulus on forehead makes parasympathetic nervous system be activated in healthy male, and it can be interpreted that mild cold stimulus make healthy human be relaxed. Also, subjects have different fondness of thermal stimulus according to their Cold or Heat condition Preferences. Last test series shows that we need to investigate effect of the warm stimulus heat syndrome subjects.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.20 no.1
• /
• pp.199-213
• /
• 2007

Purpose : This research was designed to determine whether HRV can be used as an assessment index in weakly postpartum women. Methods : The subjects were 232 women who admitted for postpartum care in Oriental Hospital of Woosuk University from 19, December 2005 to 21, July 2006. They took the test of CBC and HRV. And then we selected 200 cases of postpartum women. The SPSS 10.0 for windows was used to analyse the data and the simple correlation coefficient and the independent samples t-test were used to verify the results. Results : The following results were obtained : 1. There were positive correlations between items of CBC(RBC, Hb, Hct) and SDSD, RMSSD, SDNN, and also between items of CBC and log-transformed index of spectral analysis. There were negative correlations between items of CBC and Mean-HRV, pNN50. 2. SDNN of anemic postpartum women group significantly decreased compared with that of normal postpartum women group. HRV-Index, RMSSD and SDSD of anemic postpartum women group significantly decreased compared with that of normal postpartum women group. pNN50 of anemic postpartum women group significantly increased compared with that of normal postpartum women group. 3. Ln(TP), Ln(VLF), Ln(LF) and Ln(HF) of anemic postpartum women group significantly decreased compared with that of normal postpartum women group. Conclusion : The results suggest that the function of heart of anemic postpartum women group significantly decreased compared with that of normal postpartum women group.

• Journal of Acupuncture Research
• /
• v.21 no.6
• /
• pp.37-50
• /
• 2004

Objective : In this study, we investigated the effects of Hwangryunhaedoktang Herbal-acupuncture(HHT) at a acupoint, $G_{21}$(Kyonjong) on the Heart Rate Variability(HRV) in adults, as well as we tried to observe how HHT affects on the balance of the autonomic nervous system. Methods : The subject were comprised of 20 healthy adults, who didn't take any drugs which affected on the autonomic nervous system and had normal sinus rhythm in electrocardiogram. The control group was comprised of 9 subjects, who were injected normal saline at $G_{21}$(Kyonjong). The experiment group consisted of 10 subjects, who were injected HHT at $G_{21}$(Kyonjong). We measured HRV by CANS 3000 on three times : before, immediately after, and 20 minutes after injection. The SPSS 10.0 for windows was used to analyze the date and the Wilcoxon signed rank test (in group) and Mann-Whitney U-test(between two groups) were used to verify the results. Results : The following results were obtained ; 1. In each group, Mean-HRV and Mean-RR showed a significant change during 20 minutes after injection. But there were no significant difference between two groups(p>0.05). 2. In experiment group, 20 minutes after injection, norm LF and LHR showed a significant decrease and norm HF showed a significant increase. There were significant difference between two groups(p<0.05). Conclusions : The findings suggest that HHT at $G_{21}$(Kyonjong) in adults relatively activate parasympathetic nervous system and inactivate sympathetic nervous system.

• Journal of Korean Medicine Rehabilitation
• /
• v.15 no.2
• /
• pp.17-30
• /
• 2005

Objectives : This study was designed to evaluate the changes of autonomic nervous system by heart rate variability(HRV) test on the musculoskeletal pain patients treated with acupuncture on the Back-su points and the unfixed points, and untreated healthy adults. Methods : This clinical study have been carried out with 64 cases of musculoskeletal pain patients and 26 healthy adults. 35 patients were treated with acupunctureon on the Back-su points(Group I) and 26 patients were treated on the Unfixed points(GroupII), and two groups were tested by HRV at pre and post acupuncture treatment. 26 healthy adults(GroupIII) were tested twice by HRV without any stimulation. Results : In Group I, VAS was decresased $5.83{\pm}1.62$ to $5.17{\pm}1.89$ significantly(p<0.05) after acupuncture treatment, and LF/HF ratio was decreased significantly(p<0.05) as compared with healthy control Group. In GroupII, SDNN & RMSSD were increased singnificantly(p<0.05) as compared with other Groups. in Group I & II, MHRT was decreased significantly(p<0.05) as compared with healthy control Group. Conclusions : These results suggest that acupuncture treatment on the Back-su points was able to reduce the pain, suppress the sympathetic activities and enhance the parasympathetic activities in musculoskeletal patients.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.1
• /
• pp.418-425
• /
• 2013

In this study, the three scents effects on subjects due to EEG type, and it researched to find optimal scent to increase their amenity and productivity. EEG and HRV were compared and analyzed in the environmental test room by classifying subjects into two type: A and B. The condition of the environmental test room was in temperature 31[$^{\circ}C$], relative humidity 50[RH%], air current speed 0.02[m/s] and illuminance 1000[lux] with setting up three different scents which are Rosemary, Jasmine and Hazelnut. The result of this study, at Jasmine scent for A and B type, relative ${\alpha}$ wave, SEF50, $\frac{SMR}{\theta}$ and SDNN were revitalized, and ${\alpha}$ wave asymmetry index, HRT, stress index and fatigue degree were decreased. It was found that favorite scent of A and B type is same as Jasmine scent, but A type was more sensitive than B type about scent. Therefore Jasmine scent is very effective to increase amenity, productivity and concentration, and to decrease stress and fatigue degree.

• The Journal of Internal Korean Medicine
• /
• v.30 no.1
• /
• pp.173-180
• /
• 2009

Objectives : The aim of this study was to investigate the evaluation of gastrointestinal parasympathetic nerve activity by comparing between HRV and bowel sound parameters in patients with functional dyspepsia. Methods : 62 patients (male 22, female 40) were enrolled. HRV was measured in all patients. and TP (total power), LF (low frequency density: 0.04$\sim$0.15Hz), HF (high frequency density: 0.15$\sim$0.4Hz). and LF/HF ratio were analyzed. HF band is a reflection of parasympathetic activity. and the LF-to-HF ratio is considered a marker of sympathovagal balance. Bowel sounds were recorded at the day after, and postprandial %BS was used to indicate the gastric vagal activity after eating. HRV and bowel sound parameters were compared. and correlation between them was analyzed. Results : There was no difference in LF/HF ratio between patient group and healthy group of other report. According to values of %BS, each patient was classified into a normal (>6 %BS) or hypoactivity (<6 %BS) of gastric vagus nerve group. HF component of the hypoactivity group was not significantly higher than that of the normal group. There was no correlation between HRV and bowel sound parameters. Conclusions : Because no correlation was found between HRV and bowel sound parameters in patients with functional dyspepsia, we concluded that it is not proper to evaluate gastric vagus nerve activity by HRV measurement.

• Anxiety and mood
• /
• v.4 no.1
• /
• pp.3-10
• /
• 2008

The purpose of this review was to investigate the neurophysiological and neuroimaging characteristics of patients with depression and anxiety reported in previous studies. A literature search was conducted using Medline and psychiatric textbooks. "Electroencephalography (EEG)", "Event Related Potentials (ERP)", "functional neuroimaging", "heart rate variability (HRV)" and "depression or anxiety" were used as key words. A physiological finding indicated that there was a higher degree of relativity with regards to prefrontal dysfunction in patients with depression. Right prefrontal lobe hyperactivity and left prefrontal hypoactivity were consistently observed, and abnormalities were observed in other regions (ACC, hippocampus, amygdala, etc.). Therefore, dysfunctions in these areas are related to depressive symptoms. In patients with anxiety disorder, each emotional condition showed specific activation patterns in different brain regions, such as the prefrontal cortex, occipital lobe, temporal lobe, hippocampus, and limbic system, including the amygdala. However, in the majority of patients with anxiety disorder, the degree of activation was higher in the right hemisphere than in the left hemisphere. The current data supports that there is a difference in brain dysfunction characteristics between depression and anxiety and that the different activations of various brain regions would play a significant role in the pathophysiology of depression and anxiety disorder.

• The Journal of Internal Korean Medicine
• /
• v.44 no.1
• /
• pp.66-76
• /
• 2023

Background: The aim of this study is to investigate the use of heart rate variability on a stroke patient with autonomic dysfunction and the effectiveness of Bunshimgi-eum. Case report: The patient showed autonomic dysfunction, including chest discomfort, 煩燥 (sweating, anxiety, insomnia, nausea, lightheadedness), and abdomen discomfort (dyspepsia, heartburn) after ischemic stroke. She was treated with a herbal medicine (Bunshimgi-eum) through complex Korean medicine treatment. The effect was evaluated using heart rate variability (HRV), Mini-Mental State Examination-DS (MMSE-DS), mean pulse rate, and subjective percentage of symptoms. After treatment, the HRV score, MMSE-DS score, and subjective percentage of symptoms improved, and the pulse rate decreased from the upper boundary value. Discussion: The results suggest that HRV may be useful in evaluating stroke patients with autonomic dysfunction and that Bunshimgi-eum is suitable for treatment.

• Korean Journal of Psychosomatic Medicine
• /
• v.20 no.1
• /
• pp.59-65
• /
• 2012

Objectives : The present study takes part of the agricultural district cohort study of a certain county located in Gyeonggido and aims to investigate the difference of the heart rate variability(HRV) according to the social support level. Methods : We used data from 1727 participants of a health promotion program who are older than 40 years old. A physical examination, as well as a one-to-one interview to obtain sociodemographic characteristics, was performed with each participant. In addition, the participants completed the Medical Outcomes Study-Social Support Survey(MOS-SSS) for their the social support level to be assessed, and their HRV were measured to evaluate their autonomic function. The entire group was divided in two groups according to its MOS-SSS points to facilitate the research. Those who were evaluated as the high 25%(432 persons) were denominated as high social support (HSS) group and those who were evaluated as the low 25%(425 persons) were denominated as poor social support(PSS) group. Results : The two groups showed significant differences on the sociodemographic factor such as mean age and gender composition(p<0.05). Comparing the indices related to the HRV, the HSS group had the following values higher than the PSS group : SDNN(F=4.938, p=0.027), TP(F=8.088, p=0.005), VLF(F=6.220, p=0.013) LF (F=3.873, p=0.049). Conclusion : According to the research, the PSS group showed dysfunction on their autonomic nervous system comparing to the HSS group. The social support helps an individual overcome difficulties, helps the adaptation during the changes of circumstances and in stressful situations it serves like a buffer. Based on that, it's possible to define that a low social support level gave an impact on the autonomic function. Also, using the fact that the HRV can evaluate the autonomic function in an objective view, it was possible to visualize that it has a potential to be used as an assistant factor to evaluate the social support.

• Journal of Life Science
• /
• v.18 no.3
• /
• pp.291-297
• /
• 2008

We investigated whether 1) the combined capsaicin (75 mg), sesamin (30 mg), and L-carnitine (900 mg) (CCSC) ingestion enhances autonomic nervous system (ANS) activities including thermogenic sympathetic activity as energy metabolic modulator, 2) ${\beta}_3-AR$ polymorphism of each subject influences with ANS activity. Seven healthy males $(22.0{\pm}0.5\;yr)$ volunteered for this study. The cardiac autonomic nervous activities evaluated by means of heart rate variability of power spectral analysis were continuously measured during 5 min every 30 min for total 120 min resting condition with CCSC or placebo oral administration chosen at random. The results indicated that, there are not $Arp/Arg^{64}$ variants of the ${\beta}_3-AR$ genotypes in our subjects. There were not also significant differences in heart rate during rest between both trials. The difference of ANS activity did not reach the statistical significance between both trials. However, the significant improvement showed TOTAL power, HF component, and the indices of SNS and PNS activities before and at 30 min after CCSC ingestion (p<0.05, respectively). In conclusions, although each component of combined CCSC is associated with lipolysis and/or fat oxidation, the combined CCSC consumption is not influenced in stimulation of thermogenic sympathetic activity as modulator of energy metabolism. In rather, our results suggested that CCSC ingestion improves the balance of both SNS and PNS activities. Therefore, it will be considered many combined nutrient components for ergogenic and/or lipolysis effects as well as genetic variants affecting ANS activity in further studies.