• Journal of Life Science
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• v.32 no.7
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• pp.550-566
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• 2022

Stroke is among the leading causes of death and long-term physical and cognitive disabilities worldwide, affecting an estimated 15 million people annually. The pathophysiological process of stroke is complicated by multiple and coordinated events. The breakdown of the blood-brain barrier (BBB) in people with stroke can significantly contribute to the development of ischemic brain injury. Therefore, BBB disruption is recognized as a hallmark of stroke; thus, it is important to develop novel therapeutic strategies that can protect against BBB dysfunction in ischemic stroke. Traditional medicines are composed of natural products, which represent a promising source of new ingredients for the development of conventional medicines. Indeed, several studies have shown the effectiveness of Korean medicine on stroke, highlighting the value of Korean medicinal treatment for ischemic stroke. This review summarizes the current information and underlying mechanisms regarding the ameliorating effects of the formula, decoction, herbs, and active components of traditional Korean medicine on cerebral ischemia-induced BBB disruption. These traditional medicines were shown to have protective effects on the BBB in many cellular and animal ischemia models of stroke, and experiments in various animal species, such as mice and rats. In addition, they showed brain-protective effects by protecting the BBB through the regulation of tight junction proteins and matrix metalloproteinase-9, reducing edema, neuroinflammation, and neuronal cell death. We hope that this review will help promote further investigation into the neuroprotective effects of traditional Korean medicines and stimulate the performance of clinical trials on Korean herbal medicine-derived drugs in patients with stroke.

• Archives of design research
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• v.18 no.4 s.62
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• pp.237-246
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• 2005

This study was intended to enlighten two-faced desires of the Bauhaus, revealing that it is closely related with the child education rooted in Frobel. The Bauhaus declared to disconnect with the traditional education standing for Academies and asked students to go bad to such 'innocence' as children had. The faculty of Bauhaus tried to understand of the essence of the world through primary geometrical forms as 'purity' without any inessential things as $Fr{\ddot{o}}bel$ did. Their attempts not to admit any nonessential things, however, and dinging to purity was rather a sort of neurosis. The modernism is not different from the child art hiding sadistic and dictatorial elements behind the myth of 'innocence'. Considering the child education was born and grown with nutrition from the bourgeois development, it was not compatible with democratic ideals of the Bauhaus. While the new types of schools for children provided an excellent preparation for the Bauhaus to initiate a new design education, people of the Bauhaus were going toward a different direction from aspiration of the bourgeois, strong supporters of the new schools.

• Physical Therapy Korea
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• v.10 no.3
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• pp.71-79
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• 2003

Manual tracking is an experimental paradigm that can be used to study information processing in continuous movements involving accurate, ongoing control of motor performance. The purpose of this study was to identify the effects of knee tracking training, using the paretic side, on gait in stroke patients. Nine patients with hemiplegia participated in the study. The timed 10 m gait speed test and tracking test were administrated. The tracking test was composed with ranges of $-20^{\circ}$ to $20^{\circ}$ and $0^{\circ}$ to $60^{\circ}$. The tracking training consisted of five times every week for 4 weeks. The data were analyzed by non-parametric paired sign test of Wilcoxon. The flexion/extension error of the tracking test was significantly reduced on the paretic side, while the nonparetic side was not statistically significant. The transfer of the skill to the functional activity was shown in the significant improvement at timed 10 m gait speed test. This study shows that individuals with chronic who have impaired knee movement can be trained to improve their knee control through intensive practice at a knee movement tracking task and that the skill learned from such training is transfered to a more functional gait speed.

• Physical Therapy Korea
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• v.10 no.3
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• pp.63-70
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• 2003

The purpose of this study was to compare the difference of joint position sense between measurements. Fourteen healthy male subjects were recruited for this study. The elbow joint position senses were measured using angle reproduction test. The elbow joint position sense was assessed with three experimental conditions: ipsilateral reproduction test in open-chain condition, contralateral reproduction test in open-chain condition, ipsilateral reproduction test with weight in open-chain condition and ipsilateral reproduction test in closed-chain condition. The angular difference between stimulus position and the reproduced position (angular error) was calculated in all testing conditions to examine the accuracy of the joint position sense. One way ANOVA was used to compare the error angles in all experimental conditions. The error angles between measurements were significantly different in elbow joint. The error angles was smallest in ipsilateral reproduction test with weight in open-chain condition and was greatest in the contralateral reproduction test in open-chain condition. Findings of this study indicate that testing methods, types of task, existence of resistance should be considered in clinical assessment for the joint position sense.

• Korean Journal of Cognitive Science
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• v.17 no.4
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• pp.375-398
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• 2006

Humans learn by observing, hearing, imitating, doing, and feeling. The brain(cortex) is the central tore of this process. The recent rapid progress of brain science and the active interdisciplinary collaboration between brain science and cognitive science opens a new possibility. That is a new research Held called 'Brain-Based learning Science', 'Edutational Neuroscienre', or 'NeuroEduration' This study reviews the nature and basic assumptions of brain-based learning science, current directions in educational neuroscience research, the neuro-myths, educational implications of neuroscience, and a possibility of making a meaningful connection between brain science and education. Also the future prospects and limitations of the brain-based learning science are discussed.

• Archives of design research
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• v.18 no.2 s.60
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• pp.233-242
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• 2005

This study originates from the following problematic: Can a social history of design provide a useful methodology for the research and education of Korean design? For the understanding of the modes of socio-cultural approach to design, the chapter 2 compares the narrative mode of designer-centered history promulgated under the influence of Nikolaus Pevsner and that of socio-cultural approach advocated by Adrian Forty. The chapter 3 studies the cases of socio-cultural approach to Korean design through the domestic exhibitions like 'Everyday Life, Memory and History,' 'A Glimpse into the Society through Campaigns,' and 'Design Culture in Korea 1910-1960' which attempted the socio-cultural approach to the visual culture of modern/contemporary Korea. In the chapter 4, this study investigates into the meanings and characteristics of socio-cultural approach in the design research and education, End argues for the necessity of the introduction of qualitative research methodology.

• Archives of design research
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• v.18 no.1 s.59
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• pp.245-252
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• 2005

In this paper, I am going to analyze a commercial film narrative focused on a temporal order through the theory of narrative discourse by Gerard Genette. Advertisements has a special quality or feature to be convertible into mythological hyper reality to advertise an product effectively. In this process, narrative in a commercial film has visual variations using a temporal order to show an glamorously advertisements in television. The reason that narrative in a commercial film is subject to variation with a temporal order, duration, frequency is to get some aesthetic effect for making sure people see them. Under the influence of postmodernism, image making like a pop-art became the first consideration in a commercial film with the consequence that representation as a signifier came to be more important than object as a signified. As a commercial film have more sensational image as a result of visual variation, images in a commercial film became vague so that it does not explain or express an advertising concept dearly. However, those aspects have assets that it gives the TV audience a room for interpretation in advertisements by themselves.

• Journal of radiological science and technology
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• v.10 no.1
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• pp.61-67
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• 1987

Authors tested the grid functions with various thickness of acryl phantom, radiation field size and diameter of shielding lead. The results are as followed: 1. The characteristic values of grid are affected by phantom thickness, but free from radiation field size in the diagnostic useful range. 2. The quantity of scattered radiation was decreased according to the diameter of shielding lead under 20mm, and then the diameter the smaller the better, in accordance with proposed KS standard. 3. The quantity of primary radiation was increased a little at the 80mm diameter radiation field size, but did not have much differences. Therefore, it was thought that it is needed to limit beam size in case of absolute values in accordance with any standards, but it has no matter to use 100 mm diameter in case of relative values just to campare with.

• Journal of radiological science and technology
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• v.10 no.1
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• pp.43-47
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• 1987

Authors have tested on the characteristics, image qualities and clinical applications of Konica Hi-ortho X-ray film MGH. The results are as followed; 1. The speeds of KM/MG, MGH were as about 2.7 times, and those of KR/MG, MGH were as about 4.5 times as compared with LT-II/A and the tube voltage influenced upon KM/MG, MGH over 80 kVp, upon KR/MG, MGH over 90kVp. 2. Good image definition by the detection of Burger Phanton KM/MGH, KM/MG, and LT-II/A, and good I.Q. values by the detection of Hawlet Chart LT-II/A, KM/MGH, and KM/MG in that order. Therefore, MGH film could reduce the patient dose steeply, and furthermore, provide high image quality by the high contrast and then, it will be very useful to abdominal angiography and cerebral angiography.

• Korean Journal of Child Studies
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• v.26 no.2
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• pp.27-41
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• 2005

The purpose of this study was to test the reliability and validity of the Infant Montessori Performance Assessment Scales developed by the authors. Subjects of the study consisted of 132 Montessori teachers and 50 infants who were attending Montessori home school throughout the whole country, using census method. Infant's age ranged from 6 to 24 months. Data were analysed by using SAS 8.2 PC program. Statistical methods employed were frequency, Cronbach's alpha, Kappa coefficient, test-retest correlation, construct validity, and concurrent validity. The Cronbach's alpha of 6 sub-scales included physical, creativity, practical life, sense, language, and cognitive education, which ranged from .70 to .86. And the! correlation of the test/re-test was .72. The correlation between the 6 sub-scales of Infant-Montessori Performance Assessment Scales and the total scores of 6 items ranged from .06 to .84. Therefore, the construct validity of Infant Montessori Performance Assessment Scales was verified. The Kappa coefficient of inter-rater reliability was .76. The correlation between the Infant Montessori Performance Assessment Scales and the Standardized Korean Creativity Traits Checklist(K-CTC) and the Korean Child Social Maturity Scales showed non-significant levels of .16 and .12 respectively. Conclusively, Infant Montessori Performance Assessment Scales developed by the authors were verified through the above reliability and validity tests. Specifically the Infant Montessori Performance Assessment Scales showed the relationship of the convergent and divergent validity with the Korean Child Social Maturity Scales and the Standardized Korean Creativity Traits Checklist, respectively.