• Journal of the Korean Institute of Telematics and Electronics C
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• v.36C no.10
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• pp.17-28
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• 1999

In this paper, an ASIC emulation system called ACE (ASIC Emulator) is proposed. It can produce the prototype of target ASIC in a short time and verify the function of ASIC circuit immediately The ACE is consist of emulation software in which there are EDIF reader, library translator, technology mapper, circuit partitioner and LDF generator and emulation hardware including emulation board and logic analyzer. Technology mapping is consist of three steps such as circuit partitioning and extraction of logic function, minimization of logic function and grouping of logic function. During those procedures, the number of basic logic blocks and maximum levels are minimized by making the output to be assigned in a same block sharing product-terms and input variables as much as possible. Circuit partitioner obtain chip-level netlists satisfying some constraints on routing structure of emulation board as well as the architecture of FPGA chip. A new partitioning algorithm whose objective function is the minimization of the number of interconnections among FPGA chips and among group of FPGA chips is proposed. The routing structure of emulation board take the advantage of complete graph and partial crossbar structure in order to minimize the interconnection delay between FPGA chips regardless of circuit size. logic analyzer display the waveform of probing signal on PC monitor that is designated by user. In order to evaluate the performance of the proposed emulation system, video Quad-splitter, one of the commercial ASIC, is implemented on the emulation board. Experimental results show that it is operated in the real time of 14.3MHz and functioned perfectly.

• Journal of the Korea Convergence Society
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• v.8 no.11
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• pp.49-56
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• 2017

Curling sweeping is one of important motion to control the position of the curling stone, and sweeping speed and applied force to the broom pad are major research subjects. In this study, a device was developed to measure the force applied to the curling broom pad in curling sweeping motion, and two load cells were mounted between the broom pad and pad holder. Analog signals generated from the load cells were sampled about 300 times per second using a micro controller, and then converted to 10-bit digital signals. Calibration of the load cell and set up of regression equations to convert the measured electrical signals into mass (force) was done by three M1 class weights, and the developed system was designed as wearable device to minimize increasing of total weight of the broom. Same force was applied to the developed system and a force plate that was using as a reference force measurement system in field of sports, and the difference between the measured values were showed about $0.909{\pm}1.375N$(mean and standard deviation). The developed system could be applied other kinds of study which required force measurement function similar to sweeping motion.

• Journal of Gastric Cancer
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• v.6 no.3
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• pp.132-138
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• 2006

Purpose: Dopamine is a neurotransmitter, but in the GIT, the roles of dopamine are a regulator of epithelial cell proliferation, an endogenous protective factor, and a regulator of stomach cancer cell proliferation. By using two different gastric-cancer cell lines, we assessed the effects of dopamine and dopamine receptors on the proliferation of human gastric-cancer cells. Materials and Methods: To assess the effects of dopamine and dopamine receptors on the proliferation of human gastric-cancer cells, we investigated cell proliferation and the expression of D1, D2L, and D2S receptor in two gastric-cancer cell lines, SNU 601 and KCU-C2. The effects of dopamine and dopamine receptors on the level of the cell proliferation were determined by staining with an A/H/E (acridine orange, hoechst and ethidium bromide) mixture. Results: After dopamine treatment, the cell viability was significantly decreased in SNU 601 cells (P<0.05) where the D2L receptor was absent, but not in KCU-C2 cells. After treatment with raclopride, a D2 receptor antagonist, dopamine-dose-dependent inhibition of cell proliferation was observed in SNU 601 cells (P<0.05). After treatment with SCH 23390, a D1 receptor antagonist, dopamine significantly increased ceil proliferation in KCU-C2 cells (P<0.05), but inhibited ceil proliferation in SNU 601 cells (no D2L receptor). Conclusion: The dopamine signal via the D1 or the D2S receptor inhibited proliferation of gastric-cancer cells, but that via the D2L receptor increased proliferation. These results suggest that the regulatory effects of dopamine in the gastric-cancer cell proliferation may be controlled by using dopamine receptors.

• Journal of Korea Multimedia Society
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• v.13 no.5
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• pp.710-721
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• 2010

Recently, for the advancement of embedded technology about mobile device, a new kind of service, mash-up is appeared. It is service or application combining multimedia content making tool or device and web-GIS(geographic information system) service in the mobile environment. This service can be ease to use for casual user and can apply in various ways. So, It is served in web 2.0 environment actively. But, in the mashup service, because generated multimedia contents linked with web map are new type of multimedia contents which include user's migration routes in the space such as GPS coordinates. Thus, there are no protection ways for intellectual property created by GIS web-map service users and user's privacy. In this paper, we proposed a location and user information hiding scheme for GIS web-map service. This scheme embeds location and user information into a picture that is taken by camera module on the mobile phone. It is not only protecting way for user's privacy but is also tracing way against illegal photographer who is peeping person through hidden camera. And than, we also realized proposed scheme on the mobile smart phone. For minimizing margin of error about location coordinate value against contents manipulating attacks, GPS information is embedded into chrominance signal of contents considering weight of each digit about binary type of GPS coordinate value. And for tracing illegal photographer, user information such as serial number of mobile phone, phone number and photographing date is embedded into frequency spectrum of contents luminance signal. In the experimental results, we confirmed that the error of extracted information against various image processing attacks is within reliable tolerance. And after file format translation attack, we extracted embedded information from the attacked contents without no damage. Using similarity between extracted one and original templete, we also extracted whole information from damaged chrominance signal of contents by various image processing attacks.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.422.2-422.2
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• 2014

가스장 이온원(GFIS: Gas Field Ionization Source)은 전자현미경보다 분해능이 향상된 이온현미경의 광원으로 사용하기 위하여 연구되고 있고, 큰 각전류 밀도, 작은 크기의 가상 이온원 그리고 좁은 에너지 퍼짐을 특징으로 한다. 여러 가지 장점을 가지고 있는 GFIS을 개발하기 위해서는 GFIS에서 발생된 이온빔의 형상을 관찰 것이 매우 중요하며, 이러한 관찰을 위한 시스템에는 주로 마이크로 채널 플레이트 (MCP: Micro Channel Plate)가 사용된다. MCP는 채널내부에 입사한 입자의 에너지에 의해서 생성된 이차전자를 수 천 배에서 수 백 만 배 이상 증폭시켜 형광판에 조사하고 발광시키는 방법으로 작은 신호를 영상으로 관찰 할 수 있도록 한다. MCP의 큰 증폭비는 작은 크기의 신호를 큰 신호로 증폭하여 관찰하는데 용이하여, GFIS 방법으로 생성된 이온빔(이온빔 전류 값은 pA 수준)을 관찰하기에 적합하다. 그러나 MCP를 이용하여도 증폭된 이온빔의 세기가 매우 작기때문에 생성된 이온빔 형상을 정확하게 관찰하기 위해서는 MCP의 형광판을 촬영하는 카메라 노출시간을 길게하여 데이터 수집 시간을 늘려야 하는 문제가 있다. 본 발표에서는 이온빔 형상 관찰에 소요되는 시간을 단축하기 위하여 MCP의 잡음이 GFIS의 이온빔 이미지 관찰에 미치는 영향을 분석하고 이를 제거 방법을 소개한다. 본 연구에서는 GFIS 방출 이온빔의 이미지에 포함된 MCP 잡음 특성을 장(전계)이온현미경 (Field Ion Microscope)실험을 통하여 분석하였고, 디지털 이미지 처리 방법을 이용하여 방출 이온빔 이미지에서 MCP 잡음을 제거하여 방출 이온빔 이미지만 추출할 수 있었다. 본 연구에서 제안한 방법을 GFIS 방출 이온빔 관찰시스템에 적용함으로써 기존 방법에 비해 노출시간을 단축하여 방출 이온빔을 관찰 할 수 있었으며, 노이즈 제거 효과로 향상된 이온빔 형상을 얻을 수 있었다. 본 연구결과의 관찰시간 단축과 향상된 이온빔 형상 획득은 이온현미경 개발에 필수적인 단원자 이온빔을 보다 효율적으로 개발할 수 있으며 디지털 이미지 처리로 GFIS 이온빔 생성을 자동화하는데 응용할 수 있다. 더불어 기존방법에 비해 이미지 획득을 위한 MCP의 노출시간을 단축할 수 있으므로 실험장비 수명 단축 방지 및 관리에 큰 장점이 있다.

• Geophysics and Geophysical Exploration
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• v.12 no.1
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• pp.143-153
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• 2009

Using a discrete wavenumber method, we examine the effects on Logging-While-Drilling (LWD) logs when a mismatch exists between the amplitudes or generating times of the signals from individual monopoles in a LWD multipole source. An amplitude-mismatched LWD dipole/quadrupole source produces non-dipole/non-quadrupole modes as well as flexural and screw modes. The strongest of non-dipole/non-quadrupole modes is the Stoneley mode, whose amplitude increases with increasing mismatch. However, we can recover the flexural mode signals by A-C processing, and the screw mode by A-B+C-D processing, respectively. The Stoneley mode, which has the same amplitude at the same radial distance from the borehole axis, is cancelled out by A-C and A-B+C-D processing as long as the tool is placed at the centre of the borehole. The responses from a time-mismatched LWD multipole source look like the summation of responses by two or four monopole sources off the borehole axis. However, we can avoid the misinterpretation of the formation velocities by referring to the computed dispersion curves, which are independent of the arrival times of the modes, on the frequency semblance plot.

• Journal of Life Science
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• v.21 no.9
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• pp.1288-1294
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• 2011

Resveratrol, a kind of phytochemical, is presented in grape skins. Resveratorl exerts antiproliferative, anti-cancer and pro-apoptotic activities in cancer cells. Mammalian target of rapamycin (mTOR) is a critical regulator of cellular growth and proliferation, and it is known to be a strategic target for anti-cancer therapeutic uses. mTOR is a major downstream of the PI3K/Akt pathway, which is activated in various cancer cells. It also plays an important role in the survival, proliferation and angiogenesis of cells. Cyclooxygenase-2 (COX-2) is an important protein that mediates inflammatory processes. It plays an important role in various tumors by affecting cell proliferation, mitosis, apoptosis and angiogenesis. In this study, we have investigated the effects of resveratrol on apoptosis through mTOR and COX-2 expression in MCF-7 breast cancer cells. The treatment of resveratrol with different concentrations inhibited proliferation of MCF-7. The data showed that resveratrol induced apoptotic cell death of cancer cells and decreased mTOR and COX-2 expression. These results suggest that resveratrol induces apoptosis of MCF-7 breast cancer cells by inhibiting mTOR and COX-2 expression.

• Journal of the Korea institute for structural maintenance and inspection
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• v.16 no.1
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• pp.120-130
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• 2012

As long span and complex bridges are constructed often recently, safety estimation became a big issue. Various types of measuring instruments are installed in case of long span bridge. New wireless technologies for long span bridges such as sending information through a gateway at the field or sending it through cables by signal processing the sensing data are applied these days. However, The case of occurred accidents related to bridge in the world have been reported that serious accidents occur due to lack of real-time proactive, intelligent action based on recognition accidents. To solve this problem in this study, the idea of "communication among things", which is the basic method of RFID/USN technology, is applied to the bridge monitoring system. A sensor node module for USN based intelligent bridge system in which sensor are utilized on the bridge and communicates interactively to prevent accidents when it captures the alert signals and urgent events, sends RF wireless signal to the nearest traffic signal to block the traffic and prevent massive accidents, is designed and tested by performing TinyOS based middleware design and sensor test free Space trans-receiving distance.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.4
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• pp.284-288
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• 2009

With explosively growing PPI databases, the computational approach for a prediction and configuration of PPI network has been a big stream in the bioinformatics area. Recent researches gradually consider physicochemical properties of proteins and support high resolution results with integration of experimental results. With regard to current research trend, it is very close future to complete a PPI network configuration of each organism. However, direct applying the PPI network to real field is complicated problem because PPI network is only a set of co-expressive proteins or gene products, and its network link means simple physical binding rather than in-depth knowledge of biological process. In this paper, we suggest a protein functional flow model which is a directed network based on a protein functions' relation of signaling transduction pathway. The vertex of the suggested model is a molecular function annotated by gene ontology, and the relations among the vertex are considered as edges. Thus, it is easy to trace a specific function's transition, and it can be a constraint to extract a meaningful sub-path from whole PPI network. To evaluate the model, 11 functional flow models of Homo sapiens were built from KEGG, and Cronbach's alpha values were measured (alpha=0.67). Among 1023 functional flows, 765 functional flows showed 0.6 or higher alpha values.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.3
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• pp.11-20
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• 2022

The main purpose of this study is to investigate the applicability of the shear wave tomography technology as a non-destructive testing method to evaluate the debonding between the track concrete layer (TCL) and the hydraulically stabilized based course (HSB) of concrete slab tracks for the Korea high-speed railway system. A commercially available multi-channel shear wave measurement device (MIRA) is used to evaluate debonding defects in full-scaled mock-up test specimen that was designed and constructed according to the Rheda 200 system. A part of the mock-up specimen includes two artificial debonding defects with a length and a width of 400mm and thicknesses of 5mm and 10mm, respectively. The tomography images obtained by a MIRA on the surface of the concrete specimens are effective for visualizing the debonding defects in concrete. In this study, a simple image processing method is proposed to suppress the noisy signals reflected from the embedded items (reinforcing steel, precast sleeper, insert, etc.) in TCL, which significantly improves the readability of debonding defects in shear wave tomography images. Results show that debonding maps constructed in this study are effective for visualizing the spatial distribution and the depths of the debondiing defects in the railway concrete slab specimen.