• Journal of the Korean Society of Marine Environment & Safety
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• v.19 no.1
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• pp.23-30
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• 2013

The fleet crew of Korea Coast Guard(KCG) have a wide range of roles to perform. It is already recognized that they carry dutie in inferior working conditions. Therefore, a research on leadership that concerns organizational effectiveness seemed necessary for them. This study examines whether transformational leadership style is appropriate in job satisfaction for the fleet crew of KCG. This study also proves the effect of a leadership style on job satisfaction by suggesting a hypothesis from preceding studies. In this study transformational leadership is fixed as independent variables and job satisfaction as dependent variables and six factors as demographic characteristics. It is found that Intellectual stimulation is the most influential factor, but individualized consideration is an uninfluential factor concerning job satisfaction.

• Informatization Policy
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• v.18 no.3
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• pp.50-68
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• 2011

In this paper, our goal is to examine the factors related to smartphone users' usage addiction. Based on existing literature on mobile usage behavior and addiction, we developed and tested a theoretical model and hypotheses, analyzing how variables based on the characteristics of smartphones affect smartphone usage addiction and how smartphone usage addiction affects social withdrawal. Given the literature review, a questionnaire survey was conducted; and the PLS(Partial Least Square), a kind of SEM(Structural Equation Model), was used to analyze and test the research model and hypotheses. The research results indicated that smartphone users' self-monitoring, loneliness, and smartphone characteristics affect users' usage addiction. Further, smartphone users' usage addiction affects their social withdrawal. Finally, theoretical and practical implications of these findings and directions for future research were discussed.

• Journal of Information Management
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• v.42 no.1
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• pp.137-156
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• 2011

In this paper, our goal is to examine the factors of user's satisfaction and information sharing in Social Network Services(SNS). Based on the theoretical framework like attachment theory and self-presentation theory, we develop and test a theoretical model, propose hypotheses and analyze the effects of emotional attachment and self-presentation on the satisfaction and information sharing of SNS users. For this research, questionnaire survey was conducted with literature study and the PLS(Partial Least Square) was used to analyze the measurement model and hypotheses testing. The PLS analysis results indicate that emotional attachment affects SNS users' satisfaction and information sharing. Further, information sharing is influenced by self-presentation of SNS users. Practical implications of these findings and future research implications are also discussed.

• Korean journal of applied entomology
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• v.45 no.1 s.142
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• pp.15-24
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• 2006

Inhibitor kB (IkB)-like gene has been found in the genome of Cotesia plutellae bracovirus (CpBV), which is the obligatory symbiont of an endoparsitoid wasp, C. plutellae. The open reading frame of CpBV-IkB was 417 bp and encoded 138 amino acids. Four ankyrin repeat domains were found in CpBV-IkB, which shared high homology with other known polydnavirus IkBs. Considering a presumptive cellular IkB based on Drosophila Cactus, CpBV-IkB exhibited a truncated structure with deletion of signal-receiving domains, which suggested its irreversible inhibitory role in NFkB signal transduction pathway of the parasitized host in response to the wasp parasitization. CpBV-IkB was expressed only in the parasitized diamondback moth, Plutella flostella. Its expression was estimated by quantitative RT-PCR during parasitization period, showing a constitutive expression pattern from the first day of parasitization. An indirect functional analysis of CpBV-IkB was conducted and suggested a hypothesis of host antivirus inhibition.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.4A
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• pp.507-515
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• 2008

In this study, a method predicting the displacement response of structures from the measured dynamic strain signal is proposed by using mode decomposition technique. Evaluation of bridge stability is normally focused on the bridge completed. However, dynamic loadings including wind and seismic loadings could be exerted to the bridge under construction. In order to examine the bridge stability against these dynamic loadings, the prediction of displacement response is very important to evaluate bridge stability. Because it may be not easy for the displacement response to be acquired directly on site, an indirect method to predict the displacement response is needed. Thus, as an alternative for predicting the displacement response indirectly, the conversion of the measured strain signal into the displacement response is suggested, while the measured strain signal can be obtained using fiber optic Bragg-grating (FBG) sensors. As previous studies on the prediction of displacement response by using the FBG sensors, the static displacement has been mainly predicted. For predicting the dynamic displacement, it has been known that the measured strain signal includes higher modes and then the predicted dynamic displacement can be inherently contaminated by broad-band noises. To overcome such problem, a mode decomposition technique was used. Mode decomposition technique estimates the displacement response of each mode with mode shape estimated to use POD from strain signal and with the measured strain signal decomposed into mode by EMD. This is a method estimating the total displacement response combined with the each displacement response about the major mode of the structure. In order to examine the mode decomposition technique suggested in this study model experiment was performed.

• Journal of Korean Neurosurgical Society
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• v.30 no.3
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• pp.263-271
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• 2001

Objective : Glioblastomas, the most common type of primary brain tumors, are highly invasive and cause massive tissue destruction at both the tumor invading edges and in areas that are not in direct contact with glioma cells. As a result, patients with high-grade gliomas are faced with a poor prognosis. Such grim statistics emphasize the need to better understand the mechanisms that underlie glioma invasion, as these may lead to the identification of novel targets in the therapy of high grade gliomas. Protein kinase C(PKC) is a family of serine/threonine kinases and an important signal transduction enzyme that conveys signals generated by ligand-receptor interaction at the cell surface to the nucleus. PKC appears to be critical in regulating many aspects of glioma biology. The purpose of this study was to assess accurately the role of PKC in the invasion regulation of human gliomas based on hypothesis that protein kinase C(PKC) is functional in the process of glial tumor cell invasion. Method : To test this hypothesis, U-87 malignant glioma cell line intracellular PKC levels were up and down regulated and their invasiveness was tested. Intracellular PKC level was characterized using PKC activity assays. Invasion assays including barrier migration and spheroid confrontation were used to study the relationship between PKC concentration and invasiveness. Result : The cell line which were treated by PKC inhibitor tamoxifen and hypericin exhibited decreased PKC activity and decreased invasive abilities dose dependently both in matrigel invasion assay and tumor spheroid fetal rat brain aggregates(FRBA) confrontation assay. However, the cell line that was treated by PKC activator 12-O-tetradecanylphorbol-13acetate(TPA) did not exhibit increases in either PKC activity or invasive ability. Conclusion : These studies suggest that PKC may be a useful molecular target for the chemotherapy of glioblastoma and other malignancies and that a therapeutic approach based on the ability of PKC inhibitors may be helpful in preventing invasion.

• Journal of the Korea Convergence Society
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• v.8 no.11
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• pp.461-476
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• 2017

The purpose of this study was to investigate the existing theories related to overtraining syndrome and to examine the mechanism of overtraining syndrome from the viewpoint of brain science by examining domestic and foreign literature related to the relationship between overtraining syndrome and brain neurotransmitter. The aim of this paper is to provide basic data that can improve the understanding of the mechanism of overtraining syndrome and the role of neurotransmitters and neuromodulators. The results of this study and a number of hypotheses about the overtraining syndrome were proposed, each with strengths and weaknesses. Similar symptoms that occur when the concentration of serotonin in the neurotransmitter increases are related to signs and symptoms of overtraining syndrome. However, it has not been validated to date because it can not distinguish the mechanism of the mediator between the central nervous system and the peripheral nerves. This study suggests that the mechanism of overtraining syndrome will provide important basic information to understand the complex causes of overtraining syndrome through the interaction of existing theory and brain neurotransmitter. Although there has been a lack of studies on the mechanism of overtraining syndrome and brain neurotransmitters so far, we hope that this study will provide an opportunity for more and more people to broaden their understanding of overtraining syndromes.

• Information Systems Review
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• v.15 no.1
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• pp.45-68
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• 2013

Despite improved technologies, procedures, and regulations, consumers are still uncertain about purchasing online. The objective of this study is to understand uncertainty factors in online shopping and their relationships with the consumers' intention to purchase. For this objective we derived seller anonymity, lack of product transparency, and lack of process transparency as uncertainty factors from previous researches which may affect consumers' perceived uncertainty on online shopping. Then, a causal model was developed to conceptualize the relationships between these uncertainty factors as antecedent variables and consumer's intention to purchase as consequent variable with perceived uncertainty as an intermediary variable. Purchase involvement was used as a moderating variable on the relationship between perceived uncertainty and the intention to purchase online. The model was tested empirically to find meaningful relationships among these variables. The findings indicate that all antecedent variables affect perceived uncertainty significantly and perceived uncertainty negatively affects consumers' intention to purchase. Moreover, the results of analysis show purchase involvement has a significant moderating effect on the relationship between perceived uncertainty and intention to purchase online.

• Journal of Life Science
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• v.28 no.1
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• pp.116-129
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• 2018

Living creatures possess long-conserved mechanisms to maintain homeostasis in response to various stresses. However, chronic and continuous exposure to stress can result in the excessive production of stress hormones, including catecholamines, which have harmful effects on health. Studies on the relationship between the sympathetic nervous system (SNS) and cancer have been conducted based on the traditional hypothesis that stress can promote cancer progression. Many preclinical and epidemiological studies have suggested that the regulation of ${\beta}$-adrenergic signaling, which mediates SNS activity, can suppress the progression of solid tumors. SNS activation has highly pleiotropic effects on tumor biology, as it stimulates oncogenes, survival pathways, the epithelial - mesenchymal transition, and invasion. Moreover, it inhibits DNA repair and programmed cell death and regulates the tumor microenvironment, including immune cells, endothelial cells, the extracellular matrix, mesenchymal cells, and adipocytes. Although targeted therapies on the molecular basis of tumor proliferation are currently receiving increased attention, they have clinical limitations, such as the compensatory activation of other signaling pathways, emergence of drug resistance, and various side effects, which raise the need for pleiotropic cancer regulation. This review summarizes the effects of the SNS on the development and progression of cancer and discusses the clinical perspectives of ${\beta}$-blockade as a novel therapeutic strategy for this disease.

• Korean journal of applied entomology
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• v.35 no.3
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• pp.209-215
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• 1996

DNA polymorphisms were analyzed for 8 clones of the green peach aphid, Myzus persicae Sulzer, by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR). The insect has different host preferences and was even classified into two different species, M. persicae Sulzer and Myzus nicotinae Blackman by their morphological characters, but this point is still in arguement. To identify the differences between two types of the green peach aphid by RAPD-PCR, the template DNA was extracted from 4 clones each of tobacco-feeding and non-tobacco-feeding forms and one hundred primers of 10-nucleotideslong were tested in PCR. The amplified DNAs were analyzed by agarose gel electrophoresis. Eighty-three primers gave amplified DNA fragments with 1 to 22 in number and 500 to 20,000 base pairs in length, but no amplification was observed in the other 17 primers. The average number of fragment per each amplification was about 13. In the case of 82 out of 83 random primers, band patterns of amplified DNA were identical among 8 clones, even though some differences were noticed in the intensity of specific bands. Polymorphism was detected by only one primer within the tobacco-feeding forms, but not between the two host types. The results did not detect any relationship between RAPD polymorphism and their host preference.