• Clinical and Experimental Pediatrics
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• v.48 no.12
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• pp.1317-1323
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• 2005

Purpose : This study was performed to evaluate the recent frequency of karyotypes in different sex chromosome abnormalities and to evaluate the age and clinical manifestations at diagnosis. Methods : Peripheral blood leukocytes were obtained from subjects who were clinically suspected to have sex chromosome abnormalities and referred to the cytogenetic laboratory in the Department of Pediatrics, Kyungpook National University Hospital from February 1981 to August 2001. Results : The relative frequencies of different sex chromosome abnormalities were Klinefelter(52 percent), Turner(42 percent), XXX syndrome(3 percent) and mixed gonadal dysgenesis(3 percent). The populations of different karyotypes in Klinefelter syndrome were 47,XXY(97 percent) and 46,XY/47,XYY(3 percent). The populations of different karyotypes in Turner syndrome were 45,X(67 percent,), mosaicism(23 percent), and structural aberrations(10 percent). The populations of different karyotypes in XXX syndrome were 47,XXX(67 percent,) and 46,XX/47,XXX(33 percent). All mixed gonadal dysgenesis were 45,X/46,XY. Eighty one percent of sex chromosome abnormalities was diagnosed after puberty. Patients diagnosed with Klinefelter and Turner syndrome in infancy showed nearly normal phenotypes or had minor congenital malformations. Conclusion : Early diagnoses of sex chromosome abnormalities is required to prevent associated morbidities and to maximize growth and development. We have to pay careful attention in diagnoses of Turner syndrome because of the high proportion of mosaicism and structural aberrations.

• Journal of Hospice and Palliative Care
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• v.7 no.1
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• pp.49-63
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• 2004

Purpose: The Hospice Oriented Medical Record (HOMR) was developed for assessing the pain and symptoms of terminal cancer patients. Methods and Results: The HOMR consists of an instruction for users and 2 assessment pages which include the graph showing vital signs (temperature, blood pressure, pulse, respiration rate and pain score), current problem lists, performance status, laboratory data, pain characteristics and management, sedation score, associated symptoms and drug side effects, etc. Pilot study was performed in the inpatient Hospice Care Unit in Guro Hospital, Korea University Medical Center. Because an one-week progress data was recorded in HOMR as a flow sheet, the patient's condition and pain control status could be seen at a glance. Conclusion: The HOMR is useful for assessing the terminal cancer patients because it is simple and convenient to use. Further research is needed before it can be universally used in the clinical settings.

• The Korean Journal of Emergency Medical Services
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• v.13 no.3
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• pp.71-76
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• 2009

서론(Introduction) : 의학 시뮬레이션(medical simulation)은 교육생 학습과정에서 내재된 위험이 환자에게 가해짐 없이 교육생이 실제적인 환자 상황을 경험할 수 있게 하고 여러 다양한 임상내용이 포함한 상황에 적용될 수 있다. 시뮬레이션 기술의 사용은 의학교육(medical education), 인증서(certification), 면허교부(Licensure)와 의료의 질 형성에 큰 잠재력을 가지고 있다. 복강경 수술, 내시경검사, 전문심장구조술, 응급기도관리와 외상소생을 포함한 다양한 임상시술의 수행에서 시뮬레이션이 교육생의 술기를 달성하고, 측정하고, 유지하는 유효성을 증명하였다 컴퓨터로 조절되는 시뮬레이터는 맥박, 혈압, 호흡, 대화가 가능하고, 중증질환 또는 외상환자의 치료에 필요한 같은 인명구조 시술을 수행할 수 있다. 의학 시뮬레이션은 의사, 간호사, 응급구조사와 응급 진료를 필요로 하는 환자를 치료하는 사람에게 필요하다. 최신 전문심장구조술 과정수업은 전통적인 강의와 제한된 팀 상호작용이 포함된 이틀 과정이다. 우리는 비 영어권 국제 응급구조학생의 전문심장구조술 술기능력을 알아보고, 그것을 미국 응급구조학생과 비교하고자 한다. 목적(Objective) : 이 연구의 목적은 다양한 전문심장구조술 증례 시나리오를 가진 의학 시뮬레이터를 이용하여 미국과 한국의 응급구조 학생의 능력을 비교하는 것이다. 시행 장소(Site Location) : 이 연구는 한국 제주도에 위치한 제주한라대학 스토니브룩 응급의료교육원에서 진행되었다. 학생들의 평가는 스토니브룩에 위치한 스토니브룩 대학 의료원의 한 명의 평가자(Dr. lee)에 의해 수행되었다. 방법(Methods) : 15명의 한국 응급구조학생들은 세 팀으로 무작위로 선정하였다. 5명이 한 팀이 되어 같은 증례의 시나리오를 받았다. 세 가지 시나리오는 : 첫째, 천식지속상태(Status asthmaticus), 둘째, 긴장기흉을 동반한 만성폐쇄성폐질환(COPD with tension penumothorax) 그리고 마지막으로 메가코드(megacode)를 가진 심정지 이다. 세 팀을 각각 그리고 기본인명구조술(BLS)과 전문심장구조술(ACLS)과정을 마친 미국 응급구조학생들과 비교하였다. 15명의 미국 응급구조학생들 또한 세 팀으로 무작위로 선정하였다. 이 응급구조 학생들은 플러싱병원 의료원 소속으로 그곳에서 이 연구에 참여할 뿐만 아니라 지속적인 의학교육(CME)이수를 받았다. 이들에게도 같은 세 가지 증례의 시나리오가 주어졌고 Dr lee는 총 여섯 팀을 평가하였다(한국 세 팀과 미국 세팀). 결과(Results) : 양 국가의 모든 15명의 학생이 의학시뮬레이터를 사용하여 전문심장구조술 메가코드시험을 포함한 시험에 모두 통과하였다. 비록 학생들을 무작위로 세 팀으로 나누었지만 한 팀이 이 모든 세 증례에서 다른 팀보다 뛰어났다. 제주한라대학 2번 팀은 더 나은 기도관리, 리듬인식과 임상술기를 가진 모든 중요한 활동을 얻기에서 우수했다. 그들은 핵심요구사항을 90% 이상 충족시겼다. 한국의 2번팀(G2K)은 메가코드에서 기도개방, 호흡평가, 순환징후 그리고 흉부압박수와 같은 신체검진 술기에서도 탁월했다. 게다가 다른 팀과 비교 시 리듬인식, 약물지식과 임상술기에서도 높은 점수를 받았으며 2번팀(G2K)이 6팀 중에 가장 뛰어나게 역활수행을 하였다. 결론(Conclusion) : 이 비교 연구에서 한국학생과 미국학생간에 전문심장구조술 메가코드 시험의 통과율에는 차이가 없었다. 그러나 미국학생은 세 팀 사이에 더 적은 변이로 더 일괄된 점수를 받았다. 한국학생들도 모든 세 가지 증례를 통과하였지만 이 세 팀은 미국학생 팀보다 점수에서 더 큰 변이를 보였다.

• Therapeutic Science for Rehabilitation
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• v.10 no.2
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• pp.129-140
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• 2021

Objective : The purpose of this study was to examine differences in social maturity and behavioral problems according to the level of sleep problems in children with ASD. Methods : The participants were 102 mothers of infants with ASD aged 1-5 years. The Social Maturity Scales (SMS) and Child Behavior Checklist 1.5-5 were used as the measuring tools. Results : The level of sleep problems in infants with ASD was 56.58T on the sleep problems scale. The participants were grouped based on scores on the sleep problems scale: those with scores <65 (good sleepers) or scores ≥65 (poor sleepers). Sleep problems significantly correlated with all the scales on the CBCL. However, no association was found between sleep problems and social quotients. Poor sleepers achieved significantly lower scores on the social quotient scale of the SMS than good sleepers. Poor sleepers achieved significantly higher scores in internalizing problems, externalizing problems, and DSM-oriented scales on the CBCL compared to those in the good sleepers. Conclusion : The significance of this study is that it has verified the severity of sleep problems in infants with ASD and has examined the differences in social maturity and behavioral problems between poor sleepers and good sleepers.

• Korean Public Health Research
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• v.44 no.4
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• pp.35-49
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• 2018

Objective : The purpose of this study was to investigate the risk factors of dehydration from the subjects who underwent anthropometric and blood parameters testing during a comprehensive health screening. Methods : For the study analysis, 5,391 samples with valid data of the levels of Sodium($Na^+$), BUN (Blood Urea Nitrogen) and FBS(Fasting Blood Sugar) were selected to calculate a dehydration indicator of plasma osmolality. The study data was collected from the health screening examinees who visited Sahmyook Medical Center Seoul Adventist Hospital Comprehensive Health Check-up Center from 2014.01.01 to 2015.12.31. The relationship between dehydration and age group, BMI, disease exposures(hypertension, diabetes mellitus, dyslipidemia, kidney disorder) were analyzed by gender. Results : The odds ratio of dehydration showed statistical significance from age ${\geq}50$ in both male and female, respectively. The female obese group was vulnerable to dehydration while the male study group showed no statistical significance in the BMI difference. The disease exposed groups(hypertension, diabetes mellitus, dyslipidemia, kidney disorder) were vulnerable to dehydration. Also, the more types of disease carried by the exposed patients, the higher odds ratio and susceptibility to dehydration. Conclusions : Aging, increasing BMI, and exposed to diseases were found to be the risk factors for vulnerability to dehydration. To prevent dehydration, special caution to be taken for those in the ${\geq}50s$ group, along with controlling BMI and chronic diseases. Further studies are suggested to investigate the risk factors of dehydration that may affect increasing plasma osmolality as a potential stimulus mechanism in disease outbreaks.

• Journal of the korean academy of Pediatric Dentistry
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• v.46 no.3
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• pp.283-292
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• 2019

The purpose of this study was to evaluate the relationship between Body Mass Index (BMI) and dental caries by considering related factors in Korean children and adolescents. A total of 2,874 children, aged from 2 to 18, who participated in the Korea National Health and Nutrition Examination Survey 2013 - 2015 were included. BMI ($kg/m^2$) was calculated, and participants were categorized into 4 groups using age and gender specific criteria. Decayed and filled teeth index were obtained. There were statistically significant differences in DMFT index between overweight group and other groups (p < 0.01). Underweight group showed the highest mean DMFT index compared to other groups. These findings suggest that children in obesity and underweight group tend to have more caries than normal group in this study.

• Korean Journal of Child Education & Care
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• v.18 no.4
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• pp.159-173
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• 2018

Objective: The main purpose of this study was examine the relationships among goodness of fit between mother and child, child's self-esteem and quality of home environment. Also, the moderating effects of quality of home environment among preschoolers were investigated in the relation of interest in this study. Methods: The study subjects were 195 children who attended preschools, located in Seoul. The preschoolers' self-esteem was tested by the trained researcher, and both of levels of goodness of fit between the mother-child and quality of home environment were rated by the mothers of this study. Results: The main results of this study found that levels of preschoolers' self-esteem were positively related to goodness of fit between the mother-child, and quality of home environment. Furthermore, the effects of goodness of fit between mother-child on preschoolers' cognitive, physical, and emotional self-esteem were moderated by the quality of home environment. Conclusion/Implications: Along with those findings, implications for research and practice were discussed.

• The Journal of Korean Academy of Sensory Integration
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• v.17 no.1
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• pp.19-29
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• 2019

Objective : The aim of this study was to verify validity of the Activity Participation Assessment for school-age children. Methods : A questionnaire consisting of 30 items from the APA, 75 items from the PACS, and 55 items from the CAPE was administered to elementary school students. A total of 207 questionnaires were analyzed. Confirmatory factor analysis was performed to confirm the construct validity of the APA. Convergence validity and discriminant validity were verified with the average variance extracted (AVE) and the square of the correlation coefficient. The discriminant validity was the Pearson correlation coefficient of the APA, PACS, and CAPE. Results : The results of the analysis were as follows: 1) For construct validity, the goodness of fit of the modified hierarchical second-order factor model was found to be appropriate (p < .001), 2) For convergent validity, the AVE was higher than .50 for all latent variables, 3) For discriminant validity, the AVE of the latent variable was greater than the square of the correlation coefficient (0.239), 4) For concurrent validity, the correlation between the total sum of the APA and PACS scores showed a positive correlation in all domains, and the correlation coefficient ranged from .303 to .647 at a statistically significant level (p < .01), 5) The correlation coefficient between the total sum of the APA and CAPE scores was .490 for recreational activities, .329 for physical activities, .571 for social activities, .401 for skill-based activities, and .390 for self-improvement activities. All domains showed a positive correlation, and were statistically significant (p < .01). Conclusion : APA can be used as a valid assessment tool to measure the participation of school aged children.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.489-492
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• 2014

This thesis provides the design of system software for the management of radiation dose that is generated using computer tomography(CT). Because radiation exposure is different depending on the difference in sensitivity to each part for each of the patient's body, if we will be able to manage an appropriate amount of radiation, it is possible to estimate the radiation exposure of the patient as a result. Recently, radiation leakage incident of Japanese nuclear power plant was in the news internationally and there is a growing interest not only a nuclear power plant, to medical radiation exposure. In spite of the fact that currently safety management of radiation is under control only the workers of the radiation involved, exposure management of patients until now have been required. Surgery and inspection using the radiation in Korea will increase, due to this medical exposure has increased, but it is a reality that medical institution don't know the level of radiation exposure applied to the patient. Therefore a system for managing the radiation exposure of the patient from the medical institution is required. This paper proposes a design of a software program to manage the radiation exposure of CT is an typical imaging tool to use the radiation in the medical institution. By check the amount of radiation dose and set the limit of dose, we would help to optimize the medical exposure of the patient.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.170-177
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• 2018

The purpose of this study was to investigate the effects of circulation exercise on health related fitness and metabolic syndrome risk factors obese in middle age women. Twenty, obese middle age women($BMI<25kg/m^2$) composed of circulation exercise group(EX, n=10), the control group(CON, n=10). The variables of health related fitness, metabolic syndrome risk factors were measured in all the subjects before the start and after the end of 12 week circulation exercise program(60~80 %HRR, 3 times per week, 30~40 mins). The test data were analyzed by paired t-test and repeated ANOVA, and the alpha level of p<.05 was set for all tests of significance. Health related fitness and metabolic syndrome risk factors were measured pre and 12 weeks of post exercise training. %body fat(p <.01) was significantly decreased in EX group compared to CON group. LBM(p <.05), muscular endurance(p <.05), flexibility(p <.05) and cardiorespiratory endurance(p <.001) were significantly increased in EX group compared to CON group. WC(p <.05), SBP(p <.01), DBP(p <.05), Glucose(p <.05) and TG(p <.05) were significantly decreased in EX group compared to CON group. HDL-C(p <.01) was significantly increased in EX group compared to CON group. These results suggest that 12 weeks of circulation exercise training improves health related fitness and metabolic syndrome risk factors. Thus, this newly proposed circulation exercise modality can be a useful therapy to improve both health related fitness and metabolic syndrome risk factors in obese middle age women.