• Journal of Digital Policy
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• v.3 no.2
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• pp.15-22
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• 2024

This study was conducted to identify the cause of turtle neck syndrome that occurs in a pharmacists and the relationship between the height and table height and to suggest a table height appropriate for height. By conducting correlation and regression analysis of the turtle neck index, NDI, and VAS. As a result of calculating, the relationship between the pharmacist's height and table height, which is good for preventing turtle neck, is less than about 65cm, and it was proven that the height of the table is a major factor in causing or worsening turtle neck syndrome. It is believed that further follow-up research is needed to determine whether the calculated through this paper is effective and can be applied to other occupational groups.

• The Journal of Korean Medicine
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• v.21 no.3
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• pp.119-128
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• 2000

This study was carried out to determine if Salviae Radix extract (SRE) exerts protective effect against alterations in membrane transport function in rabbits with rhabdomyo lysis-induced acute renal failure. Acute renal failure was induced by intramuscular administration of glycerol (50%, 10 ml/kg). GFR in the glycerol-injected animals was reduced to 11% of the basal value and the fractional $Na^{+}$ excretion was increased to 7.8-fold, indicating generation of acute renal failure. When animals received SRE pretreatment for 7 days prior to glycerol injection, such changes were significantly attenuated. The fractional excretion of glucose and phosphate was increased more than 43-fold and 27-fold, respectively, in rabbits treated with glycerol alone. However, they were increased to 17-and 4.3-fold, respectively, in SRE-pretreated rabbits, and these values were significantly lower than those in rabbits treated with glycerol alone. Uptakes of glucose and phosphate in purified isolated brush-border membrane, the $Na^{+}-K^{+}-ATPase$ activity in microsomal fraction, and cellular ATP levels all were reduced in rabbits treated with glycerol alone. Such changes were prevented by SRE pretreatment. Uptakes of organic ions, PAH and TEA, in renal cortical slices were inhibited by the administration of glycerol, which was prevented by SRE pretreatment. Pretreatment of an antioxidant DPPD significantly attenuated the increase in the fractional excretion of glucose and phosphate induced by rhabdomyolysis. These results indicate that rhabdomyolysis causesimpairment inreabsorption of solutes in the proximal tubule via the generation of reactive oxygen species, and SRE pretreatment may provide the protection against the rhabdomyolysis-induced impairment by its antioxidant action.

• Journal of the korean academy of Pediatric Dentistry
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• v.42 no.3
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• pp.242-248
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• 2015

Maximum mouth opening is regarded as an important tool used to evaluate the clinical function of temporomandibular joint and the masticatory system. It has been reported that children can also exhibit severe dysfunction or pain in some cases of temporomandibular disorder. The purpose of this study was to measure the normal maximum mouth opening in Korean children and to analyze the correlations between mouth opening and the associated factors. Maximum mouth opening was measured from 151 healthy children between the ages of 2 and 6 years old. Age, height, weight, and mouth width were also recorded. As a result, the mean maximum mouth-opening was $37.72{\pm}5.10mm$. While the values were greater in boys than in girls without statistical significance, the increases of maximum mouth opening based on age, height, weight, and mouth width were significant (p < 0.05). In children, positive correlation coefficients were observed between maximum mouth opening and the associated factors and height showed the highest correlation. In conclusion, we collected data of the normal range of maximum mouth opening in Korean children, and this study can be utilized as a basis in diagnosing pediatric temporomandibular disorder and safety standard of mouth opening during dental procedures.

• The Journal of the Korea Contents Association
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• v.12 no.9
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• pp.250-256
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• 2012

Disease, such as osteopenia, osteoporosis, etc caused by reduced bone density are common to women after menopause and as the social medical cost increases due to osteoporosis fractures the medical interest in bone density reduction has increased. The bone density reduction is observed even for renal failure patients, due to their decreased ability to synthesize vitamin D which leads to bone fibrosis because of deficiency in calcium absorption. Thus renal failure patients not only suffer from kidney dysfunction, but also are exposed to complications, such as osteoporosis, due to reduced bone density. This research observed the change in bone density of patients receiving renal failure treatment and analyzed the change in bone density before and after kidney transplantations. Subjects were 214 renal failure patients at the department of nephrology Busan B General Hospital. The change in bone density was studied for subjects with and without kidney transplantation according to their age and sex. The research showed improvement or maintenance of bone density for subjects that received kidney transplantation, but showed a tendency of consistent decrease in bone density for subjects without kidney transplantation. Kidney transplantation can be considered as the best cure for renal failure patients, and this researched confirmed that bone density can be improved through kidney transplantation. Thus, this study can also be used as data for preventing complications due to renal failures.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.11 no.1
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• pp.74-91
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• 2005

척추의 기본적인 생체 역학적 기능은 신체 부분간의 운동을 허용하고 척수와 신경근을 보호하는 것으로서 이러한 기능을 수행하기 위해서는 척추의 역학적 안정성이 필수적이다. 척추의 안정체계는 수동적 근 골격계, 능동적 근 골격계, 그리고 신경계의 세 가지 하부체계로 나누어지며 이들 하부체계는 각각 독립적으로 안정성에 관여하고 있다. 경추의 불안정성의 문제는 비정상적으로 증가된 추간관절의 운동에 의해 염증성의 신경을 압박 또는 신장하거나 또는 통증수용기가 많이 분포하는 인대, 관절낭, 섬유륜과 종판에 비정상적인 변형을 일으키는 것을 말한다. 안정성의 장애는 근육의 기능적 측면에서 국소적 안정체계와 포괄적 안정체계의 문제로 구분할 수 있다. 불안정한 경추 환자의 임상적 양상은 일반적으로 머리가 앞으로 나오고 전방 전위된 자세로 견갑대와 승모근 상부의 과활동성을 나타낸다. 또한 능동운동은 감소되지 않으나 수동운동에서 분절의 회전운동과 병진운동의 증가와 종말감의 변화가 있다. 경추의 불안정성을 관리하기 위한 실험적 연구로 전반적인 근육 훈련, 고유수용기 훈련, 그리고 도수치료의 세 가지 주된 접근법이 있고 실제적인 접근법으로는 고유수용성 재활프로그램, 칼텐본-에반스 접근법, 그리고, 슬링운동법 등이 있다. 각 방법들은 임상에서 나름대로의 이점이 있으며 환자의 상태에 따라 이들 방법을 단독으로 또는 병행해서 적용할 수 있을 것이다. 그러나 경추에서 이러한 방법들의 효과를 입증하는 증거는 부족하여 앞으로 이러한 방법에 대한 임상적 경험보다는 그 효과를 입증할 수 있는 연구가 필요하다고 본다.

• Childhood Kidney Diseases
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• v.15 no.1
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• pp.22-28
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• 2011

Hypertension is one of the most common chronic diseases in childhood and adolescence. Untreated hypertension adversely affects many organs including heart, brain, kidney and peripheral arteries. We reviewed the complication of central nervous system caused by pediatric hypertension. Cerebral blood flows are maintained constantly in response to changes in blood pressure by cerebral autoregulation. Severe hypertension which destructs cerebral autoregulation results in acute hypertensive encephalopathy syndrome, ischemic or hemorrhagic stroke. Chronic pediatric hypertension induces learning disability and cognitive defect which are subclinical symptom prior to brain damage caused by severe hypertension. We should consider the effect of hypertension on pediatric brain because appropriate antihypertensive drugs could prevent these complications.

• KSBB Journal
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• v.23 no.5
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• pp.419-424
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• 2008

In this study, we examined the anti-diabetic activity in vitro by the crude extracts of Tetragonia tetragonioides which has been known to superior plants for the traditional prevention and treatment of stomach-related diseases. $\alpha$-Amylase and $\alpha$-glucosidase, the principal enzymes involved in the metabolism of carbohydrates, and aldose reductase, the key enzyme of the polyol pathway, have been shown to play the important roles in the complications associated with diabetes. A hexane (HX) fraction of T. tetragonioides were shown to inhibit more than 50% of salivary and pancreatin $\alpha$-amylase activity at concentration of 2.882 mg/mL and 2.043 mg/mL, respectively. In addition, the HX and ethylacetate (EA) fraction showed the highest inhibitory activity on yeast $\alpha$-glucosidase at values of $IC_{50}$ of 0.723 mg/mL and 1.356 mg/mL respectively. The HX, dichloromethane (DCM) and EA fraction showed more higher inhibitory activity on yeast $\alpha$-glucosidase than commercial agent such as 1-deoxynorjirimycin and acarbose. Also, the aldose reductase from human muscle cell had been inhibited strongly by the DCM fraction and HX fraction at 51.95% and 47.22% at a concentration of 1 mg/mL, respectively. Our study, for the first time, revealed the anti-diabetic potential of T. tetragonioides and this study could be used to develop medicinal preparations or nutraceutical and functional foods for diabetes and related symptoms.

• Journal of Preventive Medicine and Public Health
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• v.26 no.1 s.41
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• pp.49-64
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• 1993

To provide the basic data for assessment of renal dysfunction related to silicosis, urinary N-acetyl-$\beta$-D-giucobarninidase(NAG) activity known as a sensitive markers for early renal damage were measured in 58 silicosis patients, and control subjects of 40 pulmonary tuberculosis Patients and 51 official workers. The results were summarized as fellows. 1. The values of blood urea nitrogen and serum creatinine in all subjects were within reference limits. But the mean value of urinary NAG activity($7.25{\pm}7.31U/g\;creatinine$) was beyond reference value and more sensitive test than others. 2. The mean value of urinary NAG activity in silicosis group was $11.98{\pm}9.05U/g\;creatinine$ and significantly higher than in tuberculosis and healthy group(p<0.01), but the mean values of NAG activity in tuberculosis and healthy group were not different(p>0.05). 3. The value of NAG activity in tuberculosis had a tendency to be increased according to severity of disease, but that was not significant(p>0.05). The value of NAG activity was increased significantly by use of nephrotoxic antituberculosis drugs(p<0.05). 4. The value of NAG activity in silicosis had a tendecy to be increased according to the size of nodule, use of nephrotoxic antituberculosis drugs and shortness of onset duration, but the increase was not significant(p>0.05). 5. After excluding the users of nephrotoxic antituberculosis drugs, the mean values of NAG activity in healthy control and in tuberculosis control were same as 3.63 U/g creatinine and 3.60 U/g creatinine, respectively. But the mean value of NAG activity in silicosis group was remarkably increased as 10.90 U/g creatinine(p<0.01). As above results, even though there are no abnormal finding in screening renal function test, silicosis can be related with renal dysfunction. And it will be very useful to apply urinary NAG activity in health management of workers exposed to dust.

• Journal of the korean academy of Pediatric Dentistry
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• v.39 no.2
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• pp.161-165
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• 2012

Lowe syndrome, also known as oculocerebrorenal syndrome, is a rare genetic disorder involving eyes, kidney, brain and musculoskeletal system, and occurs predominantly in males. The patient with Lowe syndrome is characterized with congenital cataracts, glaucoma, prominent forehead, thin and sparse hair, mental and growth retardation, muscular hypotonia, renal dysfunction, and metabolic bone disease. We have experienced a 10-year-old boy with Lowe syndrome who had poor oral hygiene and trouble for teeth brushing. To manage his behavior and systemic metabolic disorder, sedation was performed during dental care. Excessive calculus formation in this patient is caused by both medication and lack of ability to maintain oral hygiene. The dental management of those patients has to be focused on prevention due to difficulties in dental treatment and dangers of general anesthesia for the Lowe syndrome.

• Analytical Science and Technology
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• v.26 no.1
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• pp.11-18
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• 2013

Perchlorate ($ClO{_4}^-$) is the material that is used as propellants of rockets and material of explosive as a form of ammonium perchlorate salts. Ammonium perchlorate solution of high concentration is recovered from expired rocket through demilitarization process by the water-jet method. If people take perchlorate in food and water, it interferes with adsorption of iodide which is the substance needed to synthesize thyroid hormone in the thyroid gland. It has an bad influence upon disturbing pregnancy and synthesis of growth hormone. So the effective method is necessary to remove perchlorate anion in water. By considering economic aspect, we studied effective desorption (regeneration) of perchlorate anion from adsorbent with studies on removal and adsorption of perchlorate anion. Desorption experiment was conducted as batch type. Depending on various conditions (concentration, pH, cation anion form) elution, we evaluated amount, efficiency of desorption(amount of adsorption/desorption ${\times}$ 100). Also, research confirmed the efficiency of mixed resins between anion exchange resin and activated carbon and expected synergic effect from advantages of both adsorbents.