• The Korean Nurse
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• v.5 no.3 s.23
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• pp.89-95
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• 1966

아기들은 출생 첫날부터 모르는 사이에 미생물에 대해서 숙주로써의 역할을 하게된다. 이들 미생물 중의 어떤 것은 아기의 가장 좋은 친구가 되기도 한다. 왜냐하면 아기를 병들게 하는 대신에 아기로 하여금 병에 대해서 저항력을 갖게 하기 때문이다. 반면 병원성균은 드물게 존재하며, 항상 위험하다. 여기 세균학자인 간호원이 널리 퍼지고 위험한 미생물, 그들의 습성, 침입해오는 방법을 서술하였고, 안전한 신생아 실을 유지하는 방법을 서술했다.

• Clinical and Experimental Pediatrics
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• v.48 no.11
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• pp.1212-1218
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• 2005

Purpose : Forward pulmonary blood flow may be absent in some neonates with Ebstein's anomaly by anatomical or functional pulmonary atresia in association with the elevated pulmonary vascular resistance, patent ductus arteriosus and tricuspid regurgitation. We reviewed the presentation and outcomes of symptomatic neonates with Ebstein's anomaly focusing on the pulmonary atresia. Methods : Clinical presentation and outcome of 15 symptomatic neonates with Ebstein's anomaly seen at Asan medical center from 1998 to 2004 were reviewed. Results : Ten(67%) of 15 patients showed no forward pulmonary blood flow and 6 of them had functional pulmonary atresia. $O_2$ saturation and pH were lower and cardiothoracic(CT) ratio in chest radiography was more increased in the patients with pulmonary atresia than in the patients without pulmonary atresia(P<0.05). pH and CT ratio were not different between the anatomical and functional pulmonary atresia group, but $O_2$ saturation was lower in functional atresia group(P<0.05). 13 patients(87%) were managed with $PGE_1$. 4 of 6 patients with functional pulmonary atresia were treated with inhaled nitric oxide. Surgery was performed in 1 of 5 patients without pulmonary atresia and in 8 of 10 patients with pulmonary atresia during follow-up period(mean 37 months). 3 patients(20%) died and none of patients without pulmonary atresia died. Conclusion : We found that most symptomatic neonates with Ebstein's anomaly had functional or anatomical pulmonary atresia. The neonates with Ebstein's anomaly who had no forward pulmonary blood flow were more symptomatic and needed surgery earlier. Further studies will be needed to distinguish effectively functional and anatomical pulmonary atresia and to manage appropriately neonates with functional atresia.

• 건강소식
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• v.13 no.4 s.125
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• pp.15-18
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• 1989

• Pediatric Infection and Vaccine
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• v.13 no.2
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• pp.124-129
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• 2006

Purpose : We investigated the causative organisms of bacterial meningitis by age distribution from 1996 to 2005. Methods : Retrospective data were obtained from the medical records with diagnosis of bacterial meningitis or neonatal meningitis from 1996 through 2005. A case was defined by isolation of organism or detection of its antigen by latex agglutination from cerebrospinal fluid. Results : A total of 46 cases(27 neonates and 19 children) were identified. 15 of 27 episodes(55.6%) of neonatal meningitis had a concomitant-positive blood culture. Group B streptococci were the most common bacterial causes of neonatal meningitis(44.4%). Nine of 12 episodes(75.0%) were late-onset infections in neonatal meningitis caused by group B streptococci. 16 of 19 children(84.2%) with bacterial meningitis beyond the neonatal period were younger than 5 years of age(median age, 23 months). Of 19 cases, 8 infections were with Streptococcus pneumoniae, 8 were with Haemophilus influenzae and 3 were with Neisseria meningitidis. Since 2001 there was no case of meningococcal meningitis in this study. Conclusion : In neonates group B streptococci are the most common causative organisms of bacterial meningitis, especially late-onset infections. In infants and young children, the predominant causes of bacterial meningitis are H. influenzae and S. pneumoniae; meningitis caused by the former are likely to decrease after the introduction of the conjugate vaccine for H. influenzae type b.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.417-425
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• 2020

This study was conducted to identify the effects of baby care using dolls on nursing students' major satisfaction, class satisfaction, and knowledge of newborn care. A quasi-experimental nonequivalent control group, pretest-posttest design was used. The subjects of the study were 95 nursing college students who agreed to participate. The control group (n=47) received lecture education consisting of watching newborn videos while the experimental group (n=48) received a practical education involving caring for a doll resembling an infant. Data were collected from March to May, 2019 and analyzed using descriptive statistics, χ²-tests, and t-tests with the SPSS/WIN 21.0 program. The major satisfaction score of the experimental group was higher than that of the control group, but it was not statistically significant (t=1.64, p=.107). The score for class satisfaction differed significantly between the experimental group and control group (t=2.08, p=.043). The knowledge of newborn care score for the experimental group was higher than that for the control group, and there was a statistically significant difference (t=-5.82, p<.001). Overall, the results show that baby care using a doll has positive effects on class satisfaction and knowledge of newborn care. In the future, it will be necessary to develop and apply effective teaching methods in line with the times.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.18 no.1
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• pp.18-22
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• 2018

Carbamoyl phosphate synthetase I (CPS1) deficiency is a rare autosomal recessive urea cycle disorder that causes hyperammonemic crisis. CPS1 is the first enzyme encoded by the CPS1 gene, which catalyzes the first step of the urea cycle. In CPS1 deficiency, ammonia, the toxic metabolite produced by the interruption of the urea cycle, is accumulated in the blood and brain, leading to hyperammonemic encephalopathy and irreversible brain damage. Here, we report a fatal case of neonatal-onset CPS1 deficiency in a 4-day-old girl presenting with recurrent seizures, who was revealed to be homozygous for c.1529delG ($p.Gly510Alafs^*5$).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.6
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• pp.3805-3812
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• 2014

The aims of this study were to examine the effects of a newborn care program (NCP) using an infant model. The subjects of this study were 48 mothers in the G city postpartum center. The NCP educational program was provided orally and via demonstration three times in two weeks. Pre and post questionnaires were given and the data was collected in July 2013 to September 2013. The findings suggest that knowledge of the newborn levels were increased significantly after the NCP (Mean=2.27 vs. 2.81, t=-7.049, p<.001). Parenting efficacy levels were increased significantly after the NCP (Mean=2.69 vs 2.89, t=-5.545, p<.001). The satisfaction with the education levels was 4.12. These findings suggest that providing a structured NCP educational program will be useful for adapting and obtaining a new mother role by improving the level of parenting efficacy and newborn care knowledge.

• Clinical and Experimental Pediatrics
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• v.46 no.9
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• pp.865-870
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• 2003

Purpose : We measured the umbilical cord arterial concentrations of isoprostane($8-iso-PGF_{2{\alpha}}$) and intended to decide whether the umbilical cord arterial concentrations of isoprostane could be used as a useful parameter for lipid peroxidation in newborn infants. Methods : The isoprostane and malondialdehyde(MDA) concentrations of the umbilical cord were measured by enzyme immunoassay and TBARS(thiobarbituric acid reactive substance) assay in 33 preterm and 28 term infants, respectively. The concentrations of isoprostane and MDA were compared between preterm infants and term infants, and were analysed for association with perinatal risk factors and neonatal complications. Results : Umbilical cord arterial concentrations of isoprostane were $704.7{\pm}635.6pg/mL$ and $421.9{\pm}306.5pg/mL$ in preterm and term infants, respectively. Umbilical cord arterial concentrations of MDA were $44.0{\pm}22.9{\mu}M/L$ and $26.2{\pm}10.7{\mu}M/L$ in preterm and term infants, respectively. Umbilical cord arterial concentrations of isoprostane and MDA in preterm infants were significantly higher than those in term infants(P<0.05). The umbilical cord arterial concentrations of isoprostane were significantly associated with perinatal risk factors such as fetal distress, oligohydramnios, and breech delivery in preterm infants and pregnancy-induced hypertension in term infants(P<0.05). Conclusion : Umbilical cord arterial concentrations of isoprostane in preterm infants were higher than those in term infants, and those are significantly associated with some perinatal risk factors.

• Clinical and Experimental Pediatrics
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• v.46 no.4
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• pp.389-392
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• 2003

Netherton's syndrome is an unusual disorder which consists of triad of ichtyosiform dermatosis, multiple defects of hair shaft and an atopic diathesis. The finding of bamboo hair is pathognomic in Netherton's syndrome and the ichthyosiform dermatosis may consist of either ichtyosis linearis circumflexa or congenital ichthyosiform erythroderma. Often, variability in the clinical features leads to a delay in diagnosis in many cases. We report a case of Netherton's syndrome diagnosed in the neonatal period. The patient presented with severe ichthyosis and confirmed microscopically distinctive bamboo hair.

• Journal of Chest Surgery
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• v.40 no.2 s.271
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• pp.155-158
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• 2007

A congenital diaphragmatic hernia, which mainly occurs in the left thorax, requires an emergency operative procedure during the neonatal periods. A right-sided congenital diaphragmatic hernia is rare, and often detected after the neonatal period due to the mild symptoms. Traditionally, the treatment repairs the diaphragmatic defect via a thoracotomy. However, good results of thoracoscopic repairs have been reported. Herein, the case of a 5-month-old girl, who received a thoracoscopic repair of a right-sided congenital diaphragmatic hernia, is reported.