• Title/Summary/Keyword: 신경준

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Dose-dependent Effects of Bee Venom Acupuncture on MPTP-induced Mouse Model of Parkinson's Disease (MPTP로 유발된 파킨슨병 Mouse 모델에 대한 봉약침의 농도의존적 효과)

  • Jun, Hyung-Joon;Kim, Yong-Suk
    • Journal of Acupuncture Research
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    • v.27 no.5
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    • pp.59-68
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    • 2010
  • 목적 : 최근 한의학에서 널리 사용되며, 신경계 질환에도 응용되고 있는 봉약침의 농도의존적 효과를 알아보기 위하여, 대표적인 신경 퇴행성 질환인 파킨슨병의 동물모델을 통해 세포보호효과와 세포사멸 및 신경염증 기전을 관찰하였다. 방법 : C57BL/6 mice에 신경독소인 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine(MPTP)를 4번 복강내 주입하여 중뇌의 흑질 도파민 신경세포를 파괴하여 Parkinson 질병동물 모델을 만든 후, 2개의 군에는 마지막 MPTP 투여 2시간 후에 1차, 그 후로 48시간이 지날 때마다 양측 신수에 각각 0.06mg/kg 농도와 0.6mg/kg 농도의 봉약침을 시행하여 총 4회 시술한 후, 도파민 세포를 측정하는 TH 면역조직 화학법을 통해 세포의 보존 정도를 관찰하고, 세포사멸과 관련된 양상을 확인하기 위하여 Caspase 3, 신경염증과 관련된 양상을 확인하기 위하여 iNOS의 발현여부를 면역 조직화학법을 이용하여 관찰하였다. 결과 : 관찰결과 MPTP 투여 후 MPTP 투여군의 흑질의 도파민 세포 수는 감소하였으나 0.6mg/kg 봉약침을 투여한 경우에는 유의성 있게 세포 수가 유지되었다. Caspase-3와 iNOS 발현억제 실험에서 0.6mg/kg 봉약침군은 MPTP 투여군과 0.06mg/kg의 봉약침군과 비교하여 Caspase-3, iNOS 발현을 유의하게 억제하였다. 결론 : 봉약침은 MPTP 투여로 인한 신경세포 손상에 대하여 농도에 따라 세포사멸 기전과 신경염증 기전을 억제함으로 신경세포를 보호하는 것으로 추정되며, 추후 적절한 경혈점 및 최적의 봉약침 농도를 찾는데 지속적인 연구가 필요할 것이다.

Radar Rainfall Adjustment by Artificial Neural Network and Runoff Analysis (신경망에 의한 레이더강우 보정 및 유출해석)

  • Kim, Soo Jun;Kwon, Young Soo;Lee, Keon Haeng;Kim, Hung Soo
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.2B
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    • pp.159-167
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    • 2010
  • The purpose of this study is to get the adjusted radar rainfalls by ANN(Artificial Neural Network) method. In the case of radar rainfall, it has an advantage of spatial distribution characteristics of rainfall while point rainfall has an advantage at the point. Therefore we adjusted the radar rainfall by ANN method considering the advantages of two rainfalls of radar and point. This study constructed two ANN models of Model I and Model II for radar rainfall adjustment. We collected the three rainfall events and adjusted the radar rainfall for Anseong-cheon basin. The two events were inputted into the Modeland Model to derive the optimum parameters and the rest event was used for validation. The adjusted radar rainfalls by ANN method and the raw radar rainfall were used as the input data of ModClark model which is a semi-distributed model to simulate the runoff. As the results of the simulation, the runoff by raw radar rainfall were overestimated but the peak time and peak runoff from the adjusted rainfall by ANN were well fitted to the observed hydrograph.

Implementation to eye motion tracking system using convolutional neural network (Convolutional neural network를 이용한 눈동자 모션인식 시스템 구현)

  • Lee, Seung Jun;Heo, Seung Won;Lee, Hee Bin;Yu, Yun Seop
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.703-704
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    • 2018
  • An artificial neural network design that traces the pupil for the disables suffering from Lou Gehrig disease is introduced. It grasps the position of the pupil required for the communication system. Tensorflow is used for generating and learning the neural network, and the pupil position is determined through the learned neural network. Convolution neural network(CNN) which consists of 2 stages of convolution layer and 2 layers of complete connection layer is implemented for the system.

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Neural Network-Based Sensor Fault Diagnosis in the Gas Monitoring System (가스모니터링 시스템에서의 신경회로망 기반 센서고장진단)

  • Lee, In-Soo;Cho, Jung-Hwan;Shim, Chang-Hyun;Lee, Duk-Dong;Jeon, Gi-Joon
    • Journal of the Korean Institute of Intelligent Systems
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    • v.14 no.1
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    • pp.1-8
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    • 2004
  • In this paper, we propose neural network-based fault diagnosis method to diagnose of sensor in the gas monitoring system. In the proposed method, using thermal modulation of operating temperature of sensor, the signal patterns are extracted from the voltage of load resistance. Also, ART2 neural network is used for fault isolation. The performance and effectiveness of the proposed ART2 neural network based fault diagnosis method are shown by simulation results using real data obtained from the gas monitoring system.

Hierarchical and Incremental Clustering for Semi Real-time Issue Analysis on News Articles (준 실시간 뉴스 이슈 분석을 위한 계층적·점증적 군집화)

  • Kim, Hoyong;Lee, SeungWoo;Jang, Hong-Jun;Seo, DongMin
    • The Journal of the Korea Contents Association
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    • v.20 no.6
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    • pp.556-578
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    • 2020
  • There are many different researches about how to analyze issues based on real-time news streams. But, there are few researches which analyze issues hierarchically from news articles and even a previous research of hierarchical issue analysis make clustering speed slower as the increment of news articles. In this paper, we propose a hierarchical and incremental clustering for semi real-time issue analysis on news articles. We trained siamese neural network based weighted cosine similarity model, applied this model to k-means algorithm which is used to make word clusters and converted news articles to document vectors by using these word clusters. Finally, we initialized an issue cluster tree from document vectors, updated this tree whenever news articles happen, and analyzed issues in semi real-time. Through the experiment and evaluation, we showed that up to about 0.26 performance has been improved in terms of NMI. Also, in terms of speed of incremental clustering, we also showed about 10 times faster than before.

A Study on GPR Image Classification by Semi-supervised Learning with CNN (CNN 기반의 준지도학습을 활용한 GPR 이미지 분류)

  • Kim, Hye-Mee;Bae, Hye-Rim
    • The Journal of Bigdata
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    • v.6 no.1
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    • pp.197-206
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    • 2021
  • GPR data is used for underground exploration. The data gathered are interpreted by experts based on experience as the underground facilities often reflect GPR. In addition, GPR data are different in the noise and characteristics of the data depending on the equipment, environment, etc. This often results in insufficient data with accurate labels. Generally, a large amount of training data have to be obtained to apply CNN models that exhibit high performance in image classification problems. However, due to the characteristics of GPR data, it makes difficult to obtain sufficient data. Finally, this makes neural networks unable to learn based on general supervised learning methods. This paper proposes an image classification method considering data characteristics to ensure that the accuracy of each label is similar. The proposed method is based on semi-supervised learning, and the image is classified using clustering techniques after extracting the feature values of the image from the neural network. This method can be utilized not only when the amount of the labeled data is insufficient, but also when labels that depend on the data are not highly reliable.

(Adaptive Structure of Modular Wavelet Neural Network Using Growing and Pruning Algorithm) (성장과 소거 알고리즘을 이용한 모듈화된 웨이블렛 신경망의 적응구조 설계)

  • Seo, Jae-Yong;Kim, Yong-Taek;Jo, Hyeon-Chan;Jeon, Hong-Tae
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.39 no.1
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    • pp.16-23
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    • 2002
  • In this paper, we propose the growing and pruning algorithm to design the optimal structure of modular wavelet neural network(MWNN) with F-projection and geometric growing criterion. Geometric growing criterion consists of estimated error criterion considering local error and angle criterion which attempts to assign wavelet function that is nearly orthogonal to all other existing wavelet functions. These criteria provide a methodology which a network designer can construct MWNN according to one's intention. The proposed growing algorithm increases in number of module or the size of modules of MWNN. Also, the pruning algorithm eliminates unnecessary node of module or module from constructed MWNN to overcome the problem due to localized characteristic of wavelet neural network which is used to modules of MWNN. We apply the proposed constructing algorithm of the optimal structure of MWNN to approximation problems of 1-D function and 2-D function, and evaluate the effectiveness of the proposed algorithm.

Adaptive Feedrate Neuro-Control for High Precision and High Speed Machining (고정밀 고속가공을 위한 신경망 이송속도 적응제어)

  • Lee, Seung-Soo;Ha, Soo-Young;Jeon, Gi-Joon
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.9
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    • pp.35-42
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    • 1998
  • Finding a technique to achieve high machining precision and high productivity is an important issue for CNC machining. One of the solutions to meet better performance of machining is feedrate control. In this paper we present an adaptive feedrate neuro-control method for high precision and high speed machining. The adaptive neuro-control architecture consists of a neural network identifier(NNI) and an iterative learning control algorithm with inversion of the NNI. The NNI is an identifier for the nonlinear characteristics of feedrate and contour error, which is utilized in iterative learning for adaptive feedrate control with specified contour error tolerance. The proposed neuro-control method has been successfully evaluated for machining circular, corner and involute contours by computer simulations.

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A Shortest Path Routing Algorithm using a Modified Hopfield Neural Network (수정된 홉필드 신경망을 이용한 최단 경로 라우팅 알고리즘)

  • Ahn, Chang-Wook;Ramakrishna, R.S.;Choi, In-Chan;Kang, Chung-Gu
    • Journal of KIISE:Information Networking
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    • v.29 no.4
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    • pp.386-396
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    • 2002
  • This paper presents a neural network-based near-optimal routing algorithm. It employs a modified Hopfield Neural Network (MHNN) as a means to solve the shortest path problem. It uses every piece of information that is available at the peripheral neurons in addition to the highly correlated information that is available at the local neuron. Consequently, every neuron converges speedily and optimally to a stable state. The convergence is faster than what is usually found in algorithms that employ conventional Hopfield neural networks. Computer simulations support the indicated claims. The results are relatively independent of network topology for almost all source-destination pairs, which nay be useful for implementing the routing algorithms appropriate to multi -hop packet radio networks with time-varying network topology.

Masking Exponential-Based Neural Network via Approximated Activation Function (활성화 함수 근사를 통한 지수함수 기반 신경망 마스킹 기법)

  • Joonsup Kim;GyuSang Kim;Dongjun Park;Sujin Park;HeeSeok Kim;Seokhie Hong
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.33 no.5
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    • pp.761-773
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    • 2023
  • This paper proposes a method to increase the power-analysis resistance of the neural network model's feedforward process by replacing the exponential-based activation function, used in the deep-learning field, with an approximated function especially at the multi-layer perceptron model. Due to its nature, the feedforward process of neural networks calculates secret weight and bias, which already trained, so it has risk of exposure of internal information by side-channel attacks. However, various functions are used as the activation function in neural network, so it's difficult to apply conventional side-channel countermeasure techniques, such as masking, to activation function(especially, to exponential-based activation functions). Therefore, this paper shows that even if an exponential-based activation function is replaced with approximated function of simple form, there is no fatal performance degradation of the model, and than suggests a power-analysis resistant feedforward neural network with exponential-based activation function, by masking approximated function and whole network.