• Journal of Chest Surgery
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• v.24 no.5
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• pp.459-462
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• 1991

The five patients with leiomyoma of esophagus were treated from 1976, to 1990. The patients were 4 men and 1 woman whose ages ranged from 28 to 53 years. One of them was asymptomatic, two had mainly dysphagia and the others complained indigestion and epigastric discomfort. There was no relationship between the severity of symptoms and the size of tumor. The preoperative diagnosis was made by esophagoscopy and esophagogram, and all of them were treated by thoracotomy and enucleation. There was no postoperative complication and the results were excellent.

• Journal of Chest Surgery
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• v.26 no.10
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• pp.815-820
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• 1993

We experienced a case of esophageal leiomyoma combined with achalasia that is very rare. Patient had suffered from severe dysphagia and postprandial vomiting and diagnosis was accomplished by esophagography, esophagoscopy, chest CT, and esophageal motility test. The operative treatment was done through left lateral thoracotomy by enucleation of the submucosal tumor and esophagomyotomy. By histopathological findings, the diagnosis of leiomyoma was confirmed and LES biopsy revealed absence of the ganglion cells of myenteric and Auerbach`s plexus. Symptoms of the patient were completely relieved and postoperative course was uneventful.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1991.06a
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• pp.44-44
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• 1991

선친성 경부 종양은 표재성, 무통성 종물로 임상적으로는 이차적 감염후 발견되는 경우가 많다. 이학적 검사 및 경부초음파 검사로 임상적 진단은 용이하나 확진을 위해서는 수술후 조직병리검사가 필수적이다. 저자들은 최근 2년간에 서울중앙병원에서 경부 종물을 주소로 내원하여 수술후 조직병리검사로 확진된 47례에 대해 후향적 조사를 실시하여 다음과 같은 결론을 얻었기에 문헌적 고찰과 함께 보고하는 바이다. 1)총 47례중 갑상설 낭종이 가장 많은 빈도를 차지하였고(31, 9%) 새성낭종(25.5%), 낭포성 히그로마(21.3%), 유표피낭포(14.9%), 혈관종(6.4% )순이었다. 2)성별 분포는 남녀간의 큰 차이 없었다. (남46.8%, 여 53.2%) 3)연령별 분포는 20대 이하에서 가장 많은 빈도를 보였다. (63.9%) 4)위치별 분포는 경부중앙(42.6%), 우측경부(38.3%), 좌측경부(19.1%)를 보였다. 5)주된 증상은 경부종물을 주소로 내원한 경우가 대부분이었으며, 증상의 기간은 1년 미만이(53.2%) 가장 많았다.

• Korean Journal of Bronchoesophagology
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• v.16 no.2
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• pp.161-164
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• 2010

Laryngeal hemangioma occurs mostly in infantile patients and infantile hemangiomas can be frequently seen in the subglottic area. So, respiratory distress is a main symptom in this entity. But adult hemangiomas are rare and can be seen in different locations such as in epiglottis, aryepiglottic fold, arytenoids and false and true vocal folds. Authors experienced a case of mixed hemangioma at the right aryepiglottic fold in a 42 years-old-man who was presented with snoring, throat foreign body sense for 3 months. So, we report this case with a review of the literature.

• Journal of Chest Surgery
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• v.35 no.4
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• pp.318-321
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• 2002

The esophageal lymphoma is a very rare feature among gastrointestinal lymphoma, and there was no surgical report in Korea. A 62-year-old male patient with submucosal tumor detected on routine esophagoscopy had resection of tumor including the esophageal mucosa, which was confirmed as esophageal lymphoma. As the severe leakage was detected on esophagogram on post-op 7th day, esophagectomy and esophagogastrostomy was followed. Though adjuvant chemotherapy was not performed, there were no evidence of recurrence for 1 year follow up. We experienced a patient with esophageal lymphoma and reported with brief review of literature

• Journal of Chest Surgery
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• v.33 no.7
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• pp.581-584
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• 2000

Because the penetrating cervical tracheoesophageal injury may be associated with significant morbidity and mortality, it is important to choose the optimal method of diagnosis and management in patient with tracheoesophageal injury. We obtained a satisfactory result from repair of tracheoesophageal injuries using cardiopulmonary bypass. If the bleeding from the unidentified deep injury and the spread of infection could be controlled, the repair using CPB might increase the margin of safety during operation in the similar cases.

• The Korean Journal of Nuclear Medicine
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• v.36 no.6
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• pp.344-356
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• 2002

Purpose: RBC blood pool SPECT has been used to diagnose focal liver lesion such as hemangioma owing to its high specificity. However, low spatial resolution is a major limitation of this modality. Recently, ordered subset expectation maximization (OSEM) has been introduced to obtain tomographic images for clinical application. We compared this new modified iterative reconstruction method, OSEM with conventional filtered back projection (FBP) in imaging of liver hemangioma. Materials and Methods: Sixty four projection data were acquired using dual head gamma camera in 28 lesions of 24 patients with cavernous hemangioma of liver and these raw data were transferred to LINUX based personal computer. After the replacement of header file as interfile, OSEM was performed under various conditions of subsets (1,2,4,8,16, and 32) and iteration numbers (1,2,4,8, and 16) to obtain the best setting for liver imaging. The best condition for imaging in our investigation was considered to be 4 iterations and 16 subsets. After then, all the images were processed by both FBP and OSEM. Three experts reviewed these images without any information. Results: According to blind review of 28 lesions, OSEM images revealed at least same or better image quality than those of FBP in nearly all cases. Although there showed no significant difference in detection of large lesions more than 3 cm, 5 lesions with 1.5 to 3 cm in diameter were detected by OSEM only. However, both techniques failed to depict 4 cases of small lesions less than 1.5 cm. Conclusion: OSEM revealed better contrast and define in depiction of liver hemangioma as well as higher sensitivity in detection of small lesions. Furthermore this reconstruction method dose not require high performance computer system or long reconstruction time, therefore OSEM is supposed to be good method that can be applied to RBC blood pool SPECT for the diagnosis of liver hemangioma.

• Journal of Life Science
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• v.21 no.3
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• pp.417-423
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• 2011

Thymosin ${\beta}4$ (TB-4) has been reported to play a key role in tumor growth, metastasis and angiogenesis. In addition, TB-4 induced the expression of vascular endothelial growth factor (VEGF) and stabilized the hypoxia-inducible factor (HIF)-$1{\alpha}$ in melanoma cells. Although the importance of thymosin ${\beta}4$ in angiogenesis and metastasis has been proven, there are few studies that show the expression patterns of TB-4, VEGF and HIF-$1{\alpha}$. This study was conducted to analyze the relationship among these proteins in various tumors. Using tissue microarray analysis, we investigated the expression patterns of TB-4, VEGF and HIF-$1{\alpha}$ in various tumors to identify the expression patterns and relationships of these proteins in certain tumors. TB-4 was highly expressed in osteosarcoma, colon adenocarcinoma, esophageal squamous cell carcinoma, kidney and urinary bladder transitional carcinoma, lung cancer, and liver cancer. HIF-$1{\alpha}$ was highly expressed in nasal cavity inverted papilloma, lung cancer, and esophageal squamous cell carcinoma. The expression patterns of TB-4 and HIF-$1{\alpha}$ were almost similar and co-localized. VEGF expression was high in the blood vessels in tumors, but usually not high in the tumors themselves. VEGF was moderately expressed in stomach cancer, liver angiosarcoma, gall bladder adenocarcinoma, and uterus endometrial adenocarcinoma. The expression patterns of VEGF shows similarities in certain tumors including stomach cancer, osteosarcoma, liposarcoma, lung cancer, liver cancer, gall bladder adenocarcinoma, esophageal squamous cell carcinoma, stomach cancer, colorectal carcinoma and renal cell carcinoma. These results suggest that the expression patterns of TB-4, HIF-$1{\alpha}$ and VEGF were co-localized and related to tumorigenesis and angiogenesis of certain tumors.

• Journal of Chest Surgery
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• v.38 no.1 s.246
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• pp.76-79
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• 2005

The coexistence of mesenchymal tumor and carcinoma in the esophagus is extremely rare. We report a case of squamous cell carcinoma located at the mucosal surface over leiomyoma of the esophagus. A 76-year-old man with complaints of 3 months onset of odynophagia was diagnosed preoperatively as squamous cell carcinoma over submucosal tumor with calcification. Esophagectomy and esophagogastrostomy were performed through the right thoracotomy and upper median laparotomy. The patient is doing well without evidence of recurrence in the 25 months after resection. We discuss the pathogenesis and possible relations between the two tumors.

• Journal of Chest Surgery
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• v.40 no.7 s.276
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• pp.520-522
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• 2007

Bronchogenic cysts are usually located in the pulmonary parenchyma or mediastinum. When they are located in the mediastinum, they are usually near the bronchus or esophagus, but they are rarely at an intramural location of the esophagus. It is very difficult to differentiate between bronchogenic cyst and esophageal cyst before the operation. We report here on a patient for whom the preoperative diagnosis was supposed to be an esophageal cyst. The esophageal cyst was excised through the longitudinal division of the esophageal muscular layer without injury of the mucosa after right thoracotomy. The pathologic report revealed intramural bronchogenic cyst. We report here of a case of bronchogenic cyst that was located in the muscle layer of the lower esophagus.