• Journal of KIISE:Computing Practices and Letters
• /
• v.10 no.4
• /
• pp.299-308
• /
• 2004

In this paper, we propose a probabilistic framework to predict the interaction probability of proteins. The notion of domain combination and domain combination pair is newly introduced and the prediction model in the framework takes domain combination pair as a basic unit of protein interactions to overcome the limitations of the conventional domain pair based prediction systems. The framework largely consists of prediction preparation and service stages. In the prediction preparation stage, two appearance probability matrices, which hold information on appearance frequencies of domain combination pairs in the interacting and non-interacting sets of protein pairs, are constructed. Based on the appearance probability matrix, a probability equation is devised. The equation maps a protein pair to a real number in the range of 0 to 1. Two distributions of interacting and non-interacting set of protein pairs are obtained using the equation. In the prediction service stage, the interaction probability of a Protein pair is predicted using the distributions and the equation. The validity of the prediction model is evaluated for the interacting set of protein pairs in Yeast organism and artificially generated non-interacting set of protein pairs. When 80% of the set of interacting protein pairs in DIP database are used as teaming set of interacting protein pairs, very high sensitivity(86%) and specificity(56%) are achieved within our framework.

• The Journal of the Korea Contents Association
• /
• v.14 no.6
• /
• pp.247-254
• /
• 2014

For the purpose of early diagnosis of the breast cancer, the attention on the screening mammography has been increasing-with supply of digital mammography day by day. Image quality is decided by target materials and filter combinations. Optimized selection by a glandular density and a thickness is needed, because these combinations change x-ray spectrum and effect to image quality. The purpose of this study is to find out optimized target and filter combinations through the evaluation of quantitative image quality and to suggest means which minimize patient dose through MCNPX. In results, spatial frequency resolution evaluation which is quantitative image quality evaluation method, MTF, NPS, DQE shows that we have to select Mo/Mo combinations or Mo/Rh combinations when compressed breast is thin. but in case of that when compressed breast is thick, we have to select Rh/Rh combinations or W /Rh combinations. In a comprehensive evaluation, W!Rh combinations which are not used in thin breasts in practice was superior to all image quality evaluation. This result is somewhat different-with clinical examination results. Secondary end point was organ dose evaluation, radiation dose of opposite breast was approximately 47 ~73% effectiveness when selecting standard breast. In conculsion, the most important point is that we have to select the optimal combinations-with considering dose evaluation and various thickness.

• The KIPS Transactions:PartD
• /
• v.12D no.6 s.102
• /
• pp.889-898
• /
• 2005

Recently, one of the most challenging problems is to compose web services dynamically, that is, on demand. A number of researchers have been considerably interested in the dynamic web services composition. However, while most of them focused on the semi-automatic web services composition with a human controller, very little attention was devoted to the full automation of this process. This paper primarily focuses on the automatic web services composition techniques. The main idea is to implement an automatic web services composition system using web ontologies to realize the semantic web and workflow technologies to play a major role in E-businesses. In this paper, we propose a matching algorithm for web service discovery and present an approach based on the use of ontologies to facilitate the interoperability of web services. Finally, we describe a workflow execution plan to support the automatic web services composition, and an experimental study that shows the high performance of our system.

• Proceedings of the KAIS Fall Conference
• /
• 2006.05a
• /
• pp.360-363
• /
• 2006

본 논문에서는 디지털 콘텐츠의 암호화키를 Puzzle기법을 사용하여 Puzzle을 재배치하고 재배치한 조합도를 공개키로 암호화 하여 유선을 통하여 전송하고, 조합을 위해 사용된 해쉬값을 OTP를 생성하여 무선으로 사용자에게 전송하는 알고리즘을 제안하고, 재배치된 Puzzl 및 OTP를 E-mail과 Mobile phone을 이용하여 높은 수준의 안전성을 제안하였다. 제안 시스템을 설계하고 구현한 후 성능 평가를 위해 다양한 콘텐츠 파일을 이용하여 실험을 수행하여 제안한 시스템이 기존 시스템에 비해 높은 보안성을 검증하였다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2006.05a
• /
• pp.933-936
• /
• 2006

본 논문에서는 디지털 콘텐츠의 암호화를 Puzzle기법을 사용하여 Puzzle을 재배치하고 재배치한 조합도를 공개키로 암호화 하여 유선을 통하여 전송하고, 조합도 암호화키 OTP를 생성하여 무선으로 사용자에게 전송하는 알고리즘을 제안하고, 재배치된 Puzzle기법과 Puzzle조합도 및 OTP를 E-mail과 Mobile phone을 이용하여 높은 수준의 사용자 Deviec와 사용자 인증을 제안하였다. 제안 시스템을 설계하고 구현한 후 성능 평가를 위해 다양한 콘텐츠 파일을 이용하여 실험을 수행하여 제안한 시스템이 기존 시스템에 비해 높은 보안성을 검증하였다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2013.05a
• /
• pp.675-676
• /
• 2013

This paper presents a design method for multiple-output combinational digital logic systems using time domain based on multiplexing and common multi-terminal extension decision diagrams. The common multi-terminal extension decision diagrams represents extension valued multiple-output functions, while time domain based on multiplexing systems transmit several signals on a single lines. The proposed method can reduce the 1)hardware, 2)logic levels and 3)pins. In the logic system design, we use two types of decision diagrams, that is the common binary decision diagrams and common multi-terminal extension decision diagrams.

• KSBB Journal
• /
• v.10 no.3
• /
• pp.317-322
• /
• 1995

Insect cells were grown and infected with baculovirus for the production of recombinant protein. Later infection gave the lower expression of recombinant protein. This indicates that the expression rate is lower at higher cell concentration. This phenomena provides a well-posed optimization problem with respect to the infection time. The optimal infection time was experimentally shown to exist for the maximum productivity of recombinant protein. Also, the expression increased with the addition of 5% silkworm hemolymph. This is considered to be due to the increase of intracellular viruses and the longevity of viable cells after the infection. The production of ${\beta}$-galaclosidase increased about ten-fold with the addition of yeastolate and silkworm hemolymph for high cell density and high expression, respectively.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.16 no.1
• /
• pp.64-77
• /
• 2012

In this study, the crack detecting system with digital image processing techniques based on the mathematical morphology method was developed to detect cracks in concrete structures. In the developed system, the image combining technique of reconstructing multiple images as an entire single image considering efficient management of analysis results was applied as an additional module. The developed system was verified through a field test with the cracked concrete culvert and the crack width of 0.2 mm was able to be detected in the 40m span. In the image analysis, the difference between calculated crack width and actual crack width were less than 0.08mm. For image combination in the stitching test of pattern images, the stitched image was identical with the original picture of entire subject in the visual perception level.

• Journal of the Korean Society of Radiology
• /
• v.14 no.4
• /
• pp.375-383
• /
• 2020

This study aimed to propose a methodology for quantitatively analyzing problems resulting from the performance and combination of the ionization chamber when using an automatic exposure control (AEC) and to optimize the performance of the digital radiography (DR). In the experimental method, the X-ray quality of the parameters used for the examination of the abdomen and pelvis was evaluated by percentage average error (PAE) and half value layer (HVL). Then, the stability of the radiation output and the image quality were analyzed by calculating the entrance surface dose (ESD) and entropy when the three ionization chambers were combined. As a result, all of the X-ray quality of the digital radiography used in the experiment showed a percentage average error and a half value layer in the normal range. The entrance surface dose increased in proportion to the combination of chambers, and entropy increased in proportion to the combination of ionization chambers except when three chambers were combined. In conclusion, analysis using entrance surface dose and entropy was found to be a useful method for evaluating the performance and combination problems of the ionization chamber, and the optimal performance of the digital radiography can be maintained when two or less ionization chambers are combined.

• Journal of Biosystems Engineering
• /
• v.15 no.4
• /
• pp.319-327
• /
• 1990

시스템의 적응 제어함수를 산출하는 네트워크인 소뇌모델 선형조합 회로망을 이용한 학습제어 기법은 시스템에 영향을 주는 제어인자들의 불확실성 및 모델링의 결여에도 불구하고 오히려 안정한 실시간 제어의 구현을 가능하게 함으로써 대단한 관심을 불러 일으켜 왔다. 그러나, 센서로부터의 정보처리와 인식 그리고 복잡한 비선형 시스템의 제어에 적용하기에는 회로망 자체의 내재적 문제점들이 여전히 남아있다. 소뇌모델 선형조합 회로망을 기지 또는 미지의 시스템 모델에 효과적으로 적용하기 위해서는 네트워크에 영향을 주는 제어인자가 시스템에 미치는 영향을 분석하는 것이 필수적이다. 분할 블럭의 크기, 학습이득, 입력편이 그리고 입력변수들의 영역과 같은 네트 제어인자들은 시스템의 학습 능률 및 소요 기억용량의 크기에 중대한 영향을 미침에도 불구하고 충분히 조사되지 못한 실태이다. 물론 이들 제어인자들의 결정에는 학습 대상이 되는 시스템 함수의 형태와 적용 학습 알고리즘이 반드시 고려되어야 한다. 본 논문에서는 학습 능률성에 미치는 이들 제어인자들의 상호영향도를 저자가 제안하였던 기본 학습 알고리즘에 의거하여 조사하였다. 분석적인 방법만으로 이러한 상호영향성을 조사하기는 매우 힘들거나 거의 불가능하다고 보아지기 때문에 학습 대상함수를 먼저 규정하여 다양한 컴퓨터 모의시험을 수행하였고 그 결과를 분석하였다. 컴퓨터 모의시험의 결과에 의하여 회로망의 시스템 적용시 고려할 설계 지침을 제시하였다.