• Title/Summary/Keyword: 시스템적 평가요소

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브라디키닌 수용체 발현 및 길항제개발에 관한 연구

  • 정성현;이은순
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1993.04a
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    • pp.146-146
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    • 1993
  • 신장에서 브라디키닌(Bradikinin, BK)의 생리적 역할을 규명하기 위한 첫 단계로 토끼신장 근위세뇨관의 일차배양세포를 이용, BK 수용체를 ($^3$H) BK를 이용하여 수용체결합실험을 함과 아울러 세포배양과정에서 여러 성장인자들의 BK 수용체발현에 미치는 영향을 관찰하였다. 첫째, 토끼 신장의 피질, 수질 및 근 위세뇨관 둥 각 부위에 대한 BK 수용체결합 실험결과 신수질 부분에 가장 많은 BK 수용체가 발견되었으며 이때 해리항수는 0.52 nM, 그리고 최대결합부위는 mg 단배질당 112.5 fmol이었다. 둘째, serum free 배지에서 insulin, transferrin 그리고 hydrocortisone이 성장인자로 사용될 때 BK 수용체발현이 가장 높았으며 이 중 인슐린에 가장 큰 영향을 받았다. 한편 인슐린의 최적농도를 결정하는 실험의 결과 5 $\mu\textrm{g}$/ml매서 가장 높은 수용체발현을 나타내었으며 그 이상에서는 별다른 차이를 보이지 못했다. 세째, 위의 세 성장인자에 prostaglandin E$_1$이나 triiodothyronine을 첨가시 BK 수용체발현은 오히려 저하되었다. 네째, fetal bovine serum (FBS)과 위의 세 성장인자간의 수용체발현능을 비교한 실험에서 세포배양 후 첫 일주일에는 FBS가 세 성장인자보다 약간 나은 수용체발현능을 나타내었으나 그후 이주째에는 세 성장인자가 BK 수용체발현에 더 적절한 요소임을 보여주었다. 이상의 결과로 보아 토끼 근위세뇨관 상피세포에서의 BK 수용체발현은 세포성장인자로 insulin, transferrin, hydrocortisone 중 insulin에 가장 큰 영향을 받는것으로 보이며, 이들 세가지 성장인자는 serum free 배지에서 세포성장 및 기능에 많은 영향을 주는 것으로 생각된다.prolidine이 $K_{M}$ /K$_{H}$ 비가 가장 높았고 diphenidol이 가장 낮았다. 이상의 결과로 보아 항 histamine제의 muscarinic receptor 차단작용은 이들 약물의 항 alleragy 효과에 필요한 작용이 아니며 본 실험에서 추정된 항 histamine제의 H$_1$-receptor와 muscarinic receptor에 대한 상대적 역가는 이들 약물의 선택과 평가에 중요한 지표가 될수 있을 것으로 생각된다.ing ischemic insults. The nature of the receptor is being explored by molecular genetic techniques, and we have recently cloned two of the major subunits; some of the data will be presented.LIFO, 우선 순위 방식등을 선택할 수 있도록 확장하였다. SIMPLE는 자료구조 및 프로그램이 공개되어 있으므로 프로그래머가 원하는 기능을 쉽게 추가할 수 있는 장점도 있다. 아울러 SMPLE에서 새로이 추가된 자료구조와 함수 및 설비제어 방식등을 활용하여 실제 중형급 시스템에 대한 시뮬레이션 구현과 시스템 분석의 예를 보인다._3$", chain segment, with the activation energy of carriers from the shallow trap with 0.4[eV], in he amorphous regions.의 증발산율은 우기의 기상자료를 이용하여 구한 결과 0.05 - 0.10 mm/hr 의 범위로서 이로 인한 강우손실량은 큰 의미가 없음을 알았다.재발이 나타난 3례의 환자를 제외한 9례 (75%)에서는 현재까지 재발소견을 보이지 않고 있다. 이러한 결과는 다른 보고자들과 유사한 결과를

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Initial System for Automation of PDQ-based Shape Quality Verification of Naval Ship Product Model (제품데이터품질(PDQ) 평가에 따른 함정 제품모델의 형상 품질검증 자동화 초기 시스템)

  • Oh, Dae-Kyun;Hwang, In-Hyuck;Ryu, Cheol-Ho;Lee, Dong-Kun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.1
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    • pp.113-119
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    • 2014
  • Recently, R.O.K. Navy is increasing re-usability of design data and application of M&S(Modeling and Simulation) through the establishment of collaborative product development environment focused on Naval Ship Product Model(NSPM). As a result, the reliability of the result of design is getting better, and furthermore, a study to improve quality of construction through simulation of production/operation is in progress. Accordingly, the database construction of design data and the DB(Database) quality become important, but there was not research related to those or it was just initial state. This paper conducted research about system of the quality verification process of shape elements which compose NSPM based on the quality verification guideline of NSPM as the result of the precedent study. The hull surface was limited as verification object. The study to verify two things that application of basic drawing by the cad model of hull surface, and whether there is error in the geometric quality of cad model was progressed. To achieve this goal, the verification criteria and algorithm were defined and the prototype system which is based on was developed.

90/150 RCA Corresponding to Maximum Weight Polynomial with degree 2n (2n 차 최대무게 다항식에 대응하는 90/150 RCA)

  • Choi, Un-Sook;Cho, Sung-Jin
    • The Journal of the Korea institute of electronic communication sciences
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    • v.13 no.4
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    • pp.819-826
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    • 2018
  • The generalized Hamming weight is one of the important parameters of the linear code. It determines the performance of the code when the linear codes are applied to a cryptographic system. In addition, when the block code is decoded by soft decision using the lattice diagram, it becomes a measure for evaluating the state complexity required for the implementation. In particular, a bit-parallel multiplier on finite fields based on trinomials have been studied. Cellular automata(CA) has superior randomness over LFSR due to its ability to update its state simultaneously by local interaction. In this paper, we deal with the efficient synthesis of the pseudo random number generator, which is one of the important factors in the design of effective cryptosystem. We analyze the property of the characteristic polynomial of the simple 90/150 transition rule block, and propose a synthesis algorithm of the reversible 90/150 CA corresponding to the trinomials $x^2^n+x^{2^n-1}+1$($n{\geq}2$) and the 90/150 reversible CA(RCA) corresponding to the maximum weight polynomial with $2^n$ degree by using this rule block.

Evaluation of high power ultrasonic energy transmission characteristics of a liquid matching layer by using sonoluminescence (소노루미네센스를 이용한 액체정합층의 고출력 초음파에너지 전달특성 평가)

  • Kim, Jungsoon;Kim, Haeun;Son, Jinyoung;Kim, Moojoon
    • The Journal of the Acoustical Society of Korea
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    • v.40 no.5
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    • pp.408-416
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    • 2021
  • In the ultrasonic dispersion, in order to avoid direct contact of the radiation surface of ultrasonic transducers with a liquid sample, the liquid sample is separated by a glass container and it receives ultrasonic energy through an acoustic medium. The transmission efficiency of the ultrasonic energy in the multi-layered ultrasonic system is an important factor. In this study, we suggested a method that can improve the ultrasonic energy transfer efficiency by using a propylene glycol solution as a liquid matching layer in the multi-layered acoustic system. In this method, a propylene glycol solution was filled between the Langevin-type ultrasonic transducer and the luminol solution and the sonoluminescence phenomena in the luminol solution, which is caused by nonlinear effect of high power ultrasound radiated from the transducer, was examined by using a Photo Multiplier Tube (PMT). The transmission efficiency depending on the concentration of propylene glycol solution was observed, and we can see that as the concentration of the propylene glycol solution increased, the matching effect increased while the acoustic attenuation increased. It was confirmed that there is an optimal concentration compromised these two conflicting conditions, and the optimum concentration of the propylene glycol solution was determined experimentally.

Study on Power Distribution Algorithm in terms of Fuel Equivalent (등가 연료 관점에서의 동력 분배 알고리즘에 대한 연구)

  • Kim, Gyoungeun;Kim, Byeongwoo
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.5 no.6
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    • pp.583-591
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    • 2015
  • In order to evaluate the performance of TAS applied to the hybrid vehicle of the soft belt driven, acceleration performance and fuel consumption performance is to be superior to the existing vehicle. The key components of belt driven TAS(Torque Assist System), such as the engine, the motor and the battery, The key components of the driven belt TAS, such as the engine, the motor, and the battery, have a significant impact on fuel consumption performance of the vehicle. Therefore, in order to improve the efficiency at the point of view based on the overall system, the study of the power distribution algorithm for controlling the main source powers is necessary. In this paper, we propose the power distribution algorithm, applied the homogeneous analysis method in terms of fuel equivalent, for minimizing the fuel consumption. We have confirmed that the proposed algorithm is contribute to improving the fuel consumption performance satisfied the constraints considering the vehicle status information and the required power through the control parameters to minimize the fuel consumption of the engine. The optimization process of the proposed driving strategy can reduce the trial and error in the research and development process and monitor the characteristics of the control parameter quickly and accurately. Therefore, it can be utilized as a way to derive the operational strategy to minimize the fuel consumption.

Forecasting the Busan Container Volume Using XGBoost Approach based on Machine Learning Model (기계 학습 모델을 통해 XGBoost 기법을 활용한 부산 컨테이너 물동량 예측)

  • Nguyen Thi Phuong Thanh;Gyu Sung Cho
    • Journal of Internet of Things and Convergence
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    • v.10 no.1
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    • pp.39-45
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    • 2024
  • Container volume is a very important factor in accurate evaluation of port performance, and accurate prediction of effective port development and operation strategies is essential. However, it is difficult to improve the accuracy of container volume prediction due to rapid changes in the marine industry. To solve this problem, it is necessary to analyze the impact on port performance using the Internet of Things (IoT) and apply it to improve the competitiveness and efficiency of Busan Port. Therefore, this study aims to develop a prediction model for predicting the future container volume of Busan Port, and through this, focuses on improving port productivity and making improved decision-making by port management agencies. In order to predict port container volume, this study introduced the Extreme Gradient Boosting (XGBoost) technique of a machine learning model. XGBoost stands out of its higher accuracy, faster learning and prediction than other algorithms, preventing overfitting, along with providing Feature Importance. Especially, XGBoost can be used directly for regression predictive modelling, which helps improve the accuracy of the volume prediction model presented in previous studies. Through this, this study can accurately and reliably predict container volume by the proposed method with a 4.3% MAPE (Mean absolute percentage error) value, highlighting its high forecasting accuracy. It is believed that the accuracy of Busan container volume can be increased through the methodology presented in this study.

Design of a Web-based Java Applet for Conceptual Learning in Digital Logic Circuits and its Student Satisfaction Survey (디지털 논리회로의 개념학습을 위한 웹기반 교육용 자바 애플릿의 설계와 만족도 조사)

  • Kim, Dong-Sik;Choi, Kwan-Sun;Lee, Sun-Heum;Chung, Hye-Kyung
    • Journal of Internet Computing and Services
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    • v.16 no.4
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    • pp.61-70
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    • 2015
  • This paper presents a web-based Java applet for understanding the concepts in digital logic circuits and student satisfaction survey was carried out in order to show its educational validity. Through our educational Java applet, the learners will be capable of learning the concepts and principles related to digital logic circuit experiments and how to operate virtual experimental equipments and virtual bread board. The proposed educational Java applet is composed of five important components: Principle Classroom to explain the concepts and principles for digital logic circuit operations, Simulation Classroom to provide a web-based simulator to the learners, Virtual Experiment Classroom to provide interactive Java applet about the syllabus of off-line laboratory class, Assessment Classroom, and Management System. With the aid of the Management System every classroom is organically tied together collaborating to achieve maximum learning efficiency. Finally, we have obtained several affirmative effects such as high learning standard, reducing the total experimental hours and the damage rate for experimental equipments.

MAC Schemes for Best Effort Service in Wireless MAN: Design and Performance Analysis (무선 MAN에서 Best Effort 서비스를 위한 MAC 방식의 설계 및 성능 분석)

  • Park, Jin-Kyung;Shin, Woo-Cheol;Ha, Jun;Choi, Cheon-Won
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.43 no.11 s.353
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    • pp.128-140
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    • 2006
  • In the IEEE 802.16 Wireless MAN standard specifies the air interface of fixed point-to-multipoint broadband wireless access systems providing multiple services. Among the service classes supported between the base station and subscriber stations in the wireless MAN, the best effort service class is ranked on the lowest position in priority and is assisted by a MAC scheme based on reservation ALOHA. The wireless MAN standard, however, does not reveal every detail of the MAC scheme but only describes the skeleton of the MAC scheme. Focusing on the amount of resource that a subscriber demands by a request and the amount of resource that the base grants to a request we thus present a number of resource demand rules and resource grant rules. Also, we construct a candidate MAC scheme by implanting a pair of resource demand and grant rules into the skeleton of the MAC scheme. Meanwhile a difficult situation for the best effort service is expected wherein only scarce resource is available after most of the resource is already preempted by other services. Perceiving such a situation, we evaluate the throughput and delay performance of each candidate MAC scheme. Especially we develop an analytical method to approximately calculate the throughput in the saturated environment. From the numerical results, we observe that the candidate MAC scheme which adopts the non-gated exhaustive demand rule paired with the full grant rule attains superior performance at the expense of the fairness.

Research on the improvement of technology transfer agent system Through South Korea and China's technology transfer agent system comparison (한국과 중국의 기술거래사 자격제도 비교를 통한 기술거래사 제도개선에 관한 연구)

  • Kim, Hye-Sun
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.7 no.1
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    • pp.165-175
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    • 2012
  • Recently, accumulation of technology, transfer, absorption, and commercialization is being significantly recognized as a key factor for sustainable growth of the 21st century global economy. The government established "Technology Transfer and Commercialization Promotion Act" In order that the technology developed at public research institutions can be transferred to the private sector and commercialized; the technology developed in the private sector can be traded and commercialized. Also, the Article 14 of "Technology Transfer and Commercialization Promotion Act" is concerning technology transfer agents' registration, promotion, and support: it introduced the special status system of technology transfer agents and the government registers, manages, and supervises it. In most developed countries, the technology transfer agency is transferred to the private sector and it is referred as a technology transfer agent or technology broker. In the domestic market, despite the introduction of the above special status system and the building a various organization and transfer medium system for boosting the market's revitalization, some problems occurred; because the registration system of a technology transfer agent and legal basis and system about its following-up control fall short. For example, recently technology transfer-related performance exemption has brought the activation of technology transfer agent's registration, but there was the limit of selecting the expert above a certain level. Therefore, some countermeasures for this are urgent, In addition, through a compulsory training completion system before the technology trade agent registration is prepared, a short period of curriculum was not sufficient to provide applicants various specialized knowledge. In this research, it is considered about the reform of technology transfer agent through its comparative study in China and Korea. Some improvements are suggested for expanding the market of technology transfer commercialization, assuring the agents' service and strengthening the competitiveness.

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Design and Safety Analysis of a Role-Based Access Control Framework for Mobile Agents in Home Network Environments (홈 네트워크 환경에서 이동 에이전트의 역할에 기반한 접근제어 프레임워크 설계 및 안전성 평가)

  • Jung, Young-Woo;Ko, Kwang-Sun;Kim, Gu-Su;Eom, Young-Ik
    • The KIPS Transactions:PartC
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    • v.14C no.6
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    • pp.537-544
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    • 2007
  • A home network is a residential local area network in which digital home appliances are connected with each other. Applying the mobile agent technology to the home network is expected to provide a new computing model. In particular, mobility and asynchronous ability of mobile agent can be used to reduce network traffic generated for managing home appliances. However, in order to apply the mobile agent concept to the home network, access control for mobile agents is necessary. In the existing home network system, there is one special server, sometimes called home server This server generally has mapping tables to be updated periodically, which describes access control lists between users' authorities and corresponding devices. In this paper, we propose a role-based access control framework with mobile agents in home networks. This framework, called Secure KAgent framework, is designed and implemented based on KAgent system. It has two main characteristics: to control access permissions based on Role-Based Access Control(RBAC) scheme and to safety assign roles to mobile agents by role tickets.