• The Korean Journal of Applied Statistics
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• v.23 no.3
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• pp.521-531
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• 2010

Interval-censored observations are common in medical and epidemiologic studies; however, limited studies exist due to the complexity and special structure of interval-censoring. This paper introduces the imputation method and the self consistency method in the interval-censored data. We propose a new method of generating random numbers under an interval-censoring set-up. Through simulation studies we compare two methods under various simulation schemes in the sense of the mean squared error for estimating the median survival time and the mean integrated squared error for estimating the survival function. Under a moderate censoring percentage, the mean imputation method showed a better performance than the self-consistency method in estimating the median survival time and the survival function.

• The Korean Journal of Applied Statistics
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• v.31 no.6
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• pp.761-769
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• 2018

Simulations are important for survival analyses that deal with censored data. Cox models are widely used in survival analyses, therefore, we investigate how to generate censored data that can simulate the Cox model. Bender et al. (Statistics in Medicine, 24, 1713-1723, 2005) provided a parametric method for generating survival times, but we need to generate censoring times as well as survival times to simulate the censored data. In addition to the parametric method for generating censored data, a nonparametric method is also proposed and applied to a real data set.

• Communications for Statistical Applications and Methods
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• v.5 no.3
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• pp.819-826
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• 1998

임의중도 절단된 이 표본의 수명자료에서 누적위험함수의 비는 시간의 변화에 따른 두 집단의 위험률을 서로 비교할 수 있는 수단이 된다. 본 논문에서는 먼저 두 집단의 누적위험함수의 비에 대한 추정량을 제안하고, 제안된 추정량의 점근성을 유도하였다. 또한 누적위험함수의 비에 대한 여러 가지 동시신뢰대들을 제안하였으며, 실제 자료에 적용하여 보았다.

• The Korean Journal of Applied Statistics
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• v.20 no.1
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• pp.39-52
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• 2007

Crossover trials of new drugs in the treatment of angina pectoris, which frequently use treadmill exercise test for the assessment of its efficacy, produce censored survival times. In this paper we consider analysis approaches for censored survival times from crossover trials. Previously, a stratified Cox model for paired observation and nonparametric methods have been presented as possible analysis methods. On the other hand, the differences of two survival times would produce interval-censored survival times and we propose a Cox model for interval-censored data as n alternative analysis method. Example data is analyzed in order to compare these different methods.

• The Korean Journal of Applied Statistics
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• v.32 no.5
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• pp.753-761
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• 2019

A test procedure based on a Kendall's τ statistic is proposed for the association of bivariate interval censored data. In particular, a leverage bootstrap technique is applied to replace unknown failure times and a classical adjustment method is applied for treating tied observations. The suggested method shows desirable results in simulation studies. An AIDS dataset is analyzed with the suggested method.

• The Korean Journal of Applied Statistics
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• v.29 no.5
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• pp.823-833
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• 2016

The lifetime is a key characteristic of product quality. It is best to obtain the lifetime data of all samples, but they are often censored due to time or expense limitations. In this paper, we propose a binomial cumulative sum (CUSUM) chart to monitor the mean of type I right-censored Weibull lifetime data, for a xed value of the Weibull shape parameter. We compare the performance of the proposed binomial CUSUM chart with CUSUM charts studied previously using the steady-state average run length (ARL). The results show that the performance of the binomial CUSUM chart is better when the censoring rate is high and/or the sample size is small.

• The Korean Journal of Applied Statistics
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• v.24 no.5
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• pp.883-891
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• 2011

For survival data we sometimes want to test a log normality hypothesis that can be changed into normality by transforming the survival data. Hence the Shapiro-Wilk type statistic for normality is generalized to randomly censored data based on the Kaplan-Meier product limit estimate of the distribution function. Koziol and Green (1976) derived Cram$\acute{e}$r-von Mises statistic's randomly censored version under the simpl hypothesis. These two test statistics are compared through a simulation study. As for the distribution of censoring variables, we consider Koziol and Green (1976)'s model and other similar models. Through the simulation results, we can see that the power of the proposed statistic is higher than that of Koziol-Green statistic and that the proportion of the censored observations (rather than the distribution of censoring variables) has a strong influence on the power of the proposed statistic.

• The Korean Journal of Applied Statistics
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• v.35 no.1
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• pp.35-47
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• 2022

The receiver operating characteristic (ROC) curve was developed to quantify the classification ability of marker values (covariates) on the response variable and has been extended to survival data with diverse missing data structure. When survival data is understood as binary data (status of being alive or dead) at each time point, the ROC curve expressed at every time point results in time-dependent ROC curve and time-dependent area under curve (AUC). In particular, a follow-up study brings the change of cohort and incomplete data structures such as censoring and competing risk. In this paper, we review time-dependent ROC estimators under several contexts and perform simulation to check the performance of each estimators. We analyzed a dementia dataset to compare the prognostic power of markers.

• The Korean Journal of Applied Statistics
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• v.30 no.2
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• pp.233-241
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• 2017

Interval censored data frequently occur in observation studies where the subject is followed periodically. In this paper, our interest is to suggest a test statistic to compare the CIF of two groups with interval censored failure time data in the presence of competing risks. Gray (1988) suggested a test statistic for right censored data that motivated a well-known Fine and Gray's subdistribution hazard model. A multiple imputation technique is adopted to adopt Gray's test statistic to interval censored data. The powers and sizes of the suggested method are investigated through diverse simulation schemes. The main merit of the suggested method is its simplicity to implement with existing software for right censored data. The method is illustrated by analyzing Bangkok's HIV cohort dataset.

• Journal of the Korean Data and Information Science Society
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• v.24 no.3
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• pp.445-451
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• 2013

We consider the estimators for the parameters of the exponential model with limited replacements under the type I censoring scheme. Also, we propose the desirable number of replacements to provide the similar effects in terms of the mean square errors.