• Journal of Korean Tunnelling and Underground Space Association
• /
• v.20 no.5
• /
• pp.809-822
• /
• 2018

A quantitative risk assessment has been introduced to quantitatively evaluate fire risk as a means of performance based fire protection design in the design of railway tunnel disaster prevention facilities. However, there are insufficient studies to examine the effect of various risk factors on the risk. Therefore, in this study, the risk assessment was conducted on the model tunnel in order to examine the effects of the evacuation start time delay and the fire growth curve on the quantitative risk assessment. As a result of the analysis of the scenario, the fatalities occurred mainly when escapes in the same direction as the direction of the fire smoke movement. In addition, after the FED exceeded 0.3, the maximum fatalities occurred within 10 minutes. In the range of relatively low risk, distance between cross passages, evacuation delay time and fire growth curve were found to affect the risk, but they were found to have little effect on the condition that the risk reached the limit. Especially, in this study, it was evaluated that the evacuation delay time reduction, fire intensity and duration reduction effect were not observed when the distance between cross passages was more than 1500 m.

• Proceedings of the Korean Nuclear Society Conference
• /
• 1998.05b
• /
• pp.730-734
• /
• 1998

난포성숙호르몬(FSH)은 난소내 난포의 성장인자로 작용한다. 본 실험은 방사선 조사된 미성숙 생쥐의 난포 폐쇄가 ESH에 의해 억제되는지를 확인하는 한편 방사선어제 개발을 위한 실험모델로서의 가능성을 평가하기 위해 수행되었다. PCNA 에 의한 염색의 정도는 FSH군의 경우, 1이에 최저, 12시간과 8일에 가장 많이 염색되었으며, 방사선을 조사한 후 ESH를 주사한 경우, PCNA에 의한 염색용은 6시간 경과시어 제일 낮게 나타나고 이후 증가하는 경향성을 보였다. 즉, FSH는 방사선에 피폭된 난소내 난포외 apoptosis를 지연시키는 효과를 갖고 있음을 알 수 있었다. 본 연구의 결과, 특정물질의 방사선방어효능 평가를 위한 실험모델로서 난소내 난포를 활용할 수 있으며 특히 FSH가 나타내는 난포폐쇄 억제효과도 방사선방어제 개발을 위한 실험연구에 중요한 역할을 할 것으로 기대된다.

• Fire Science and Engineering
• /
• v.25 no.6
• /
• pp.73-82
• /
• 2011

This study was performed to analysis the influence of smoke alarm detector on evacuation safety in housing fire. The analysis was conducted by CFAST fire simulation program and building EXODUS evacuation program. The effects of the earlier response time on evacuation safety were investigated by using evacuation simulation program with several steps of different response time and smoke alarm activation time for 4 occupants. The smoke detecter was activated 37.1 second after fire. The first two mortuary were occurred for 170 seconds of response time at the end of living room near exit. But for the 37.1 seconds of response time 4 occupants evacuated safely. From this study, the fire alarm detector is more important for safety evacuation in housing fire.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.34 no.5A
• /
• pp.381-390
• /
• 2009

In this paper, we propose a seamless intra MR-BS handover scheme based on IEEE802.16j transparent. The proposed scheme estimates the outage probability of mobile stations at a base station, finds the optimum relay user, and provides low handover latency for seamless data transmission. The simulation results show that the proposed scheme outperforms the conventional handover schemes in terms of the handover latency by 65% of conventional scheme. Moreover, the proposed scheme exhibits lower packet error rate compared with the conventional handover scheme when a mobile station moves to outside of the cell coverage and reduce both outage probability and the number of handover about 50% from setting forgetting factor and redundant threshold.

• The Korean Journal of Pharmacology
• /
• v.29 no.1
• /
• pp.1-8
• /
• 1993

To elucidate involvement of platelet-activating factor (PAF) in cerebral ischemia-reperfusion injury, male Sprague-Dawley rats and albino mice of either sex were subjected to a 10-min bilateral carotid artery occlusion and 6-hr recirculation. The McGraw stroke index in mice was markedly inhibited by PAF antagonists, BN 52021 and CV 6209 (1 mg/kg, i.p., each) When they were administered 10 min before bilateral carotid artery occlusion or 1 hr after reperfusion. The increases in brain water content were significantly attenuated by treatment with BN 52021 or CV 6209 in both animals. BN 52021 exhibited a significant improvement in the postischemic blood pressure change in association with a beneficial effect on the delayed dilatation of pial arterioles after 10 min of ischemia. Thus it is suggested that PAF plays an important role as an endogenous mediator in development of cerebral ischemia-reperfusion injury, and further, specific antagonists to PAF will be able to prevent or reverse the pathological sequelae of cerebral ischemia.

• The Korean Journal of Pharmacology
• /
• v.27 no.2
• /
• pp.183-189
• /
• 1991

The present study was performed to elucidate the factors which modulate uterine prostaglandin synthesis during the implantation period in rats, by employing delayed implantation model. Administration of estradiol sharply increased uterine cAMP concentration 4 hrs later during the delayed implantation process. Concentrations of uterine PGE and $PGF_2{\alpha}$ were increased at 12 hrs after the estradiol treatment although an increase in $PGF_2{\alpha}$ was not statistically significant. The concomitant treatment of indomethacin with estradiol significantly suppressed estradiol-induced PGE and $PGF_2{\alpha}$ at 12 hrs, while uterine cAMP concentration was not suppressed. The treatment of dbcAMP without estradiol gradually increased uterine PGE and $PGF_2{\alpha}$ showing the maximum 8 hrs later, suggesting that cAMP minics estradiol effect on uterine prostaglandin synthesis during the implantation process. Furthermore, the pretreatment of theophylline, phosphodiesterase inhibitor, induced significantly greater concentrations of uterine PGE and $PGF_2{\alpha}$, compared with estradiol-only treated group. These results suggest that estradiol stimulates uterine prostaglandin synthesis and this process may be mediated by an elevation of cAMP during the delayed implantation process in rats.

• Journal of Yeungnam Medical Science
• /
• v.25 no.1
• /
• pp.41-49
• /
• 2008

Background : The central physiological derangement of hemorrhagic fever with renal syndrome (HFRS) caused by hantaan virus (HTNV) is a vascular dysfunction, manifested by hemorrhage, impaired vascular tone and increased vascular permeability. Platelet activating factor (PAF), whose actions are mediated through a specific receptor, is a potent bioactive lipid. PAF has diverse biological functions in the vascular system, such as increasing vascular permeability, adhesion of leukocytes to the endothelium and reduction of cardiac output, which result in hypotension and shock. The goal of the present study was to investigate whether PAF is involved in the pathogenesis of HFRS. For this purpose, we evaluated the effect of HTNV on the expression of PAF receptor (PAF-R) and on the activity of PAF-acetylhydrolase (PAF-AH) instead of PAF because PAF is rapidly degraded by PAF-AH in vivo. Materials and methods : To evaluate the expression of PAF-R, we performed reverse-transcription PCR, western blot and FACS analyses using HTNV-infected human umbilical vein endothelial cells (HUVECs) and non-infected (control) HUVECs. In addition, we measured the activity of plasma PAF-AH in HFRS patients and normal healthy persons. Results : The mRNA and protein expression of PAF-R was increased in HTNV-infected HUVECs compared with control HUVECs at 2 and 3 days post-infection (d.p.i.). FACS analysis showed that HTNV induced the surface expression of PAF-R in HUVECs from 2 d.p.i. The activity of plasma PAF-AH was 2.5-fold lower in HFRS patients than in normal healthy persons. Conclusion : Increased PAF-R expression by HTNV might increase the responsiveness to PAF in endothelial cells. Reduced PAF-AH activity in the blood of HFRS patients might delay PAF degradation. These results suggest that changes in PAF-R and PAF-AH by HTNV might influence to PAF activity and might be involved in the vascular dysfunction of HFRS.

• Proceedings of the KIEE Conference
• /
• 2008.10b
• /
• pp.511-512
• /
• 2008

EPLA 패킷 스케줄링 알고리즘은 IEEE 802.22 WRAN 시스템의 실시간 트래픽 전송 지원을 위한 패킷 스케줄링 알고리즘으로 참고문헌[4]으로 제안되었다. 패킷 기반 무선 전송 시스템에서 실시간 트래픽의 경우 짧은 데이터 유효 시간을 가지며, 만약 데이터 유효 시간이 초과할 경우 실시간 트래픽 데이터로써의 가치를 상실하기 때문에 시스템에서는 해당패킷을 전송하지 않고 제거해 버린다. 그러므로 실시간 트래픽의 중요한 서비스 품질(QoS) 인자인 요구된 패킷 손실율을 보장하기 위해서는 실시간 트래픽의 데이터 유효 시간을 고려하여 자원을 할당하여야 한다. 기존의 패킷 스케쥴링 알고리즘들은 많은 경우 큐의 맨 앞에 위치한 패킷의 지연 시간을 고려하지만 EPLA는 패킷이 저장되는 큐 내의 다음 프레임에서 제거 될 것으로 예상되는패킷의 손실양을 고려하여 자인을 할당함으로 기존의 실시간 패킷 스케줄링 알고리즘에 비해 훨씬 좋은 성능을 보인다. 하지만 EPLA는 예상되는 패킷 손실양을 계간하기 위해서 모든 사용자의 큐에 저장된 패킷들을 확인해야하므로 높은 복잡도를 가지는 문제점이 있다. 본 논문에서는 각 사용자로부터 피드백 받은 부채널의 상태 정보를 기반으로 사용자 큐를 확인하여 횟수를 제한함으로써 패킷 손실을 성능의 손실 없이 복잡도를 줄이는 간단한 방법을 제안하고, 실시간 트래픽인 음성 트래픽과 비디오 트래픽에 대한 시뮬레이션 결과를 통해 이를 확인한다.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2008.05a
• /
• pp.1077-1081
• /
• 2008

Soil and Water Assessment Tool(SWAT) 모형은 DEM(Digital Elevation Model)을 사용하여 지형인자를 추출하고 이를 바탕으로 수문 및 수질 모의가 이루어진다. 지형인자의 추출시 DEM 격자크기에 따라 상이한 결과를 초래할 수 있다. 그리하여 정확한 수문 및 수질 모델링에 있어 가능한 고해상도의 DEM을 사용하도록 권장하고 있다. 그러나 넓은 유역에서의 적용시 고해상도 DEM 사용에 따른 컴퓨터 처리 용량과 프로그램 실행 시 소요되는 시간상의 문제는 그 효율성에 있어서 문제시될 수 있다. 그리하여 본 연구에서는 소양강댐, 임하댐 유역을 대상으로 SWAT 모형에서 저해상도 DEM 사용으로 고해상도 DEM의 지형인자를 추출하여 자동 입력될 수 있는 모듈을 개발 적용하였다. 본 연구의 결과 소양강댐 유역을 대상으로 격자크기 20m DEM과 100m DEM을 사용하였을 때 연평균 유사량이 83.8%의 큰 차이가 발생한 반면 격자크기의 20m DEM과 본 모듈을 적용하여 20m DEM의 지형인자로 자동 보정된 100m DEM을 사용하였을 때의 연평균 유사량이 4.4%로 차이가 상당히 줄어든 것을 볼 수 있었다. 임하댐 유역의 경우는 격자크기 10m DEM과 100m DEM을 사용하였을 때 연평균 유사량이 43.4% 큰 차이가 발생하였다. 반면 격자크기 10m DEM과 본 모듈을 적용하여 10m DEM의 지형인자로 자동 보정된 100m DEM을 사용하였을 때의 연평균 유사량이 0.3%로 차이가 크게 줄어든 것을 확인 할 수 있었다. 또한 본 모듈의 검정을 위해 소양강댐 유역의 지형 자료와 유사한 충주댐 유역을 대상으로 본 모듈을 적용하여 검정을 실시하였다. 그 결과 연간 평균 유사량이 격자크기 20m와 100m의 DEM을 이용하였을 때 98.7%의 큰 차이가 발생한 반면 격자크기 20m와 본 모듈을 적용하여 보정된 경사도 값의 100m DEM을 사용하였을 때 20.7%로 차이가 크게 줄어든 것을 볼 수 있었다. 그리하여 본 연구의 결과를 통해 SWAT 모형에서의 개선된 지형인자 추출 방식을 사용하여 저해상도의 DEM 사용으로 고해상도 DEM 사용의 효과를 볼 수 있을 것이고 이로 인해 넓은 유역에서 저해상도 DEM 사용으로 컴퓨터 사용용량과 프로그램 지연 시간을 줄일 수 있을 것으로 판단된다. 향후 여러 유역을 대상으로 보정, 검정하여 보다 정확하고 통합적으로 적용될 수 있는 모듈의 개선이 필요할 것으로 사료된다.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.18 no.6
• /
• pp.1031-1040
• /
• 2023

Propagation characteristics in line-of-sight(LOS) paths in 3, 6, 10, and 17 GHz frequency bands were measured and analyzed in two different indoor corridors: second floors of Buildings D2 and E2. The measurement was designed to measure when the receiving antenna moved at 0.5 m intervals from 3 m to 30 m, while the transmission antenna was fixed. The analysis of the two indoor corridors was compared by applying basic transmission loss, root mean square (RMS) delay spread, and K-factor. For basic transmission loss, the loss coefficient of the floating intercept path loss model was higher in the indoor corridor of Building E2 than in that of Building D2. Similarly, the RMS delay spread in the time domain was greater in the indoor corridor of Building E2. However, the indoor corridor of Building D2 exhibited higher K-factor in the 3, 6, and 17 GHz bands with lower wave propagation in the 10 GHz band. Despite the 2 indoor corridors being identical, the propagation characteristics varied due to different internal structures and materials. The results provide measurement data for ITU-R Recommendations regarding various indoor environments.