• 대한방사선방어학회:학술대회논문집
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• 2010.04a
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• pp.74-75
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• 2010

• Journal of the Korean Chemical Society
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• v.36 no.1
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• pp.38-43
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• 1992

The Hammett's substituent constants were interpreted for substituted stilbenes by HMO method. The appropriate quantum chemical indices are chosen as independent contribution of the inductive and the resonance effects for substituent constants. It has been found that theoretical values, ${\sigma}_p{^{th}}$, defined as sum of the net charge, self atom polarizability and difference in HOMO energy between substituted- and unsubstituted-stilbenes, correlated with experimental Hammett's substituent constants. The dipole moments were found to be correlated with differences in ${\sigma}_p{^{th}}$ between two substituents for disubstituted stilbenes. It has been also found that transition optical spectra, ${\lambda}_{max}$ of the substituted stilbenes depend on difference between the HOMO and the LUMO energy as expected.

• Bulletin of Food Technology
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• v.20 no.1
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• pp.3-23
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• 2007

• 대한방사선방어학회:학술대회논문집
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• 2009.11a
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• pp.186-187
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• 2009

• 대한방사선방어학회:학술대회논문집
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• 2011.11a
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• pp.156-157
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• 2011

• 대한방사선방어학회:학술대회논문집
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• 2011.04a
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• pp.118-119
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• 2011

• Korean Journal of Pharmacognosy
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• v.31 no.2
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• pp.245-248
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• 2000

As a series of the studies on cultivated Korean rhubarb rhizomes (Rheum undulatum), five stilbene derivatives were screened for inhibitory activity against $5{\alpha}-reductase$. Of these, desoxyrhapontigenin, rhapontigenin, and piceatannol exhibited inhibition, whereas, two other stilbene glycosides, rhaponticin and $piceatannol-3'-O-{\beta}-D-glucopyranoside$ did not show the inhibition.

• 대한방사선방어학회:학술대회논문집
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• 2009.04a
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• pp.236-237
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• 2009

• Journal of the Korean Chemical Society
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• v.40 no.2
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• pp.32-152
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• 1996

• Korean Journal of Pharmacognosy
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• v.34 no.1 s.132
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• pp.25-27
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• 2003

In order to clarify the anti-thrombosis activity of rhubarb, we investigated the effect of stilbene derivatives from rhizomes of Rheum undulatun on cyclooxygenase activity. Stilbene derivatives (desoxyrhapontigenin, rhapontigenin, piceatannol) exhibited the inhibitory effects on COX-1, and desoxyrhapontigenin showed inhibitory effect on COX-2. These inhibitory effect may partially contributed to anti-thrombosis activity of rhubarb.