• Journal of Hospice and Palliative Care
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• v.11 no.4
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• pp.188-195
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• 2008

Purpose: The purpose of this study was to analyze the effects of aromatherapy on stress using meta-analysis. Methods: Meta-analysis was done with 21 published studies, and data were analyzed with the SAS 9.1 program. Results: Fifty eight effect size was estimated with data from 21 published studies. Overall mean effect size (ES), and mean effect size of dependence variables according to the type of intervention and subject and according to the total amount of time spent in aromatherapy were estimated. Overall mean effect size of the effects of aromatherapy was .593, and the subjective stress (.983) was most effective in the physiological faculty, followed by mean effect size of cortisol (.648) and pulse (.40). On the other hand, mean effect size of systolic blood pressure (.490) was moderate, and that of diastolic blood pressure (.401) was not large. Mean effect size of elderly (.706) cancer patients was considerable(.337). There were significant differences depending on the subjects. With regards to the types of aromatherapy, the effect size of aroma massage combined with inhalation therapy was .590, and there were no significant differences between the intervention methods. With regards to the time of intervention, $20{\sim}30$ minutes spent in aromatherapy was .730, and there were no significant differences between the times of intervention. The relationship between the effect size and intervention frequency was r=.349 and showed significant difference. Conclusion: This result suggests that aromatherapy is an effective intervention to reduce stress for subjects. Nursing intervention protocol by using aromatherapy should be developed and applied in clinical and community settings. Further studies on the effects of aromatherapy on stress should be done by using meta-analysis.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.195-195
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• 1996

우루소데옥시콜린산을 1% CMC에 현탁하여 25mg/kg 의 농도로 각각 1, 3, 6, 10일간 1일 3회씩 투여한 후. 고정틀에 묶어 고정시키고 4시간 동안 스트레스를 가하였다. 스트레스 부과후 복부를 개복하여 혈액을 채취하고 스트레스지표인 ALP, AST, ALT, LDH를 측정하였다. 한편 일부 혈액은 백혈구, 림프구수를 측정하기 위해 이용되었다. 부신 및 비장을 적출하여 무게를 측정하고 부신은 분쇄하여 아스코르빈산 함량을 정량하였다. 스트레스 부과시간에 따른 백혈구, 림프구수의 변화실험은 별도로 시행하였다.

• Proceedings of the KAIS Fall Conference
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• 2010.11b
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• pp.855-858
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• 2010

본 연구는 발달적 위기에 놓여있는 중년여성의 피로도와 스트레스 저항력 그리고 정서와의 상관관계를 알아보기 위하여 뇌신경 생리학적 지표인 뇌파 측정을 이용하여 분석해 보고자 하였다. 2005년 3월부터 2009년 6월까지 한국정신과학연구소에 뇌파 측정을 의뢰한 우리나라 중년여성 4403명(35세~65세)을 기준으로 선정된 뇌기능 지수(긴장도, 항스트레스지수, 정서지수)를 시계열 선형분석과 상관분석으로 한 결과 중년여성의 피로도, 스트레스 저항력 그리고 정서에는 밀접한 관계가 있었다. 그러므로 사회적으로나 가정적으로 성숙하고 책임감 있는 중년여성의 역할이 필요한 현대사회에서, 중년기의 심리적 생리적 문제에 적극적으로 대처하는 것이 개인생활은 물론 가족의 원만한 기능과 안녕을 유지, 증진하는데 반드시 필요하다.

• Proceedings of the Korea Information Processing Society Conference
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• 2014.04a
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• pp.1012-1013
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• 2014

본 논문에서는 일상생활 중 지속적으로 심장 상태를 모니터링 할 수 있는 무구속 의자형 심탄도 측정시스템을 개발하였다. 또한 구현된 시스템에서 측정된 생체신호를 이용하여 주관적인 감정자극의 스트레스를 분석하기 위한 연구를 수행하였다. 수준을 분석하고자 하였다. 실험은 시스템에 착석하여 실시간으로 시청각 자극 실험을 수행하였고, 심박수와 심박변이도의 시간영역 및 주파수영역 파라미터를 확인하였다. 확인된 심박변이도의 파라미터는 시청각 도중 기술한 인간의 감정들을 체계화하여 2차원 공간에 여러 감정들의 관계를 나타낸 제임스 러셀(J. Russell)의 감정모델을 주관적인 감정 자극에 의한 스트레스 지표 나타내어 비교 분석하였다. 실험결과는 RMSSD, LF/HF 파라미터가 스트레스 수준 분류에 사용될 수 있는 잠재력을 가지고 있음을 증명한다.

• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.416.2-417
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• 2004

심혈관계 질환(CVD, Cardiovascular disease, CHD, Coronary heart disease)은 심장의 관상동맥에 염증반응과 혈전으로 인해 죽상경화중이 생겨 관상동맥이 좁아지거나 막히는 결과를 초래하는 질환으로 관상동맥질환, 고혈압, 말초혈관질환, 협심증, 심근경색증, 중풍 등이 포함된다. 심혈관계 질환의 위험인자들에는 서구화된 식생활, 유전, 나이, 성, 고혈압, 당뇨, 고지혈증, 비만, 운동부족, 스트레스, 흡연, 가족력 등이 있다. 그러나 식생활의 변화로 인한 심혈관계 질환과 생화학적 지표의 변화 및 관련 기전에 대한 연구는 거의 없었다.(중략)

• Journal of the Korean Society of Food Science and Nutrition
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• v.40 no.11
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• pp.1532-1536
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• 2011

In this study, the antioxidative activity of Artemisia capillaris T. extract on the proliferation and differentiation of MC3T3-E1 cells under $H_2O_2$-induced oxidative stress was investigated in order to determine its protective effect against oxidative stress as well as its availability as an antioxidant material related to treatment of bone diseases. As a result, the total polyphenol content of A. capillaris extract was 90.10 mg/g, whereas the flavonoid content was 4.45 mg/g. A. capillaris extract increased proliferation of MC3T3-E1 cells under $H_2O_2$-induced oxidative stress, and also increased the proliferation of differentiated osteoblast cells under oxidative stress. In addition, two differentiation markers, alkaline phosphatase activity and mineralization level, in A. capillaris extract tended to increase. These results indicate that A. capillaris extract suppresses the damage to osteoblasts caused by oxidative stress, which demonstrates its availability as an antioxidant material for preventing bone diseases.

• Proceedings of the Korean Statistical Society Conference
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• 2004.11a
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• pp.111-116
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• 2004

스트레스 수준이 논을 것으로 예상되는 공군사관학교 수험생의 신체검사 결과로부터 신체건강 지표인 혈액 내 생화학적 요인들과 정신건강 지표인 다면 인성검사 점수를 추출하여 통계적 상관성 및 유의성을 비교 분석하였다 사관생도들 중 $10\%$의 표본을 추출하여 사관생도와 수험생 집단간의 특성 비교를 위한 비교집단으로 이용하였다. 수험생과 사관생도 집단 간의 특성 요인 비교는 Mann-whitney U 검정과 Kruskal-Wallis 검정을 이용하였다. 수험생 집단 내에서 혈중 요인 및 정신건강 지표인 MMPI 점수는 정상범주에 있었고 두 요인 간 상관성은 발견할 수 없었다. 그러나 사관생도와 수험생 집단 간의 특성 요인들에 대한 유의성 검정 결과, 특히 2학년생도들의 혈액 내 혈구 수 및 활동성 또는 적극성과 관련된 MMPI 하위척도에서 수험생 집단과 매운 유의한 차이를 보이는 특이한 현상을 발견할 수 있었고 이에 대한 해석을 언급하였다.

• Journal of the Korean Institute of Landscape Architecture
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• v.43 no.5
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• pp.1-12
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• 2015

This study analyzes the physiological healing effects on users according to forest types. Forest types are classified into Chamaecyparis obtusa, Quercus serrata and Pinus densiflora and the subjects of this study, 64 hypertensives, 59 diabetics and 59 ordinary people, were tested to observe their physiological effects. The index of physiological reaction comprises electroencephalogram(EEG), heart rate variability(HRV), blood pressure and cortisol level. An analysis of the stress-buffering effect from the physiological reactions of the overall subjects indicates that Quercus serrata forests have a higher stress-buffering effect than others in terms of central nervous, endocrine and autonomic nervous systems. Chamaecyparis obtusa forests are contributory to soothing stress in the central nervous and endocrine systems. Pinus densiflora forests contribute in some indexes of the endocrine and autonomic nervous systems. In contrast, Pinus densiflora forests are less influential on a stress-buffering effect than the other two. In the level of the effect for lowering blood pressure, Chamaecyparis obtusa and Quercus serrata forests are more effective than Pinus densiflora forests. Therefore, staying in the first two forests can heighten the healing effect of the lowering of blood pressure for hypertensive patients. Every forest is efficacious to lowering diabetic blood glucose levels. Spending time in Quercus serrata forests is more effective for hypoglycemic.

• Journal of Food Hygiene and Safety
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• v.30 no.2
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• pp.202-209
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• 2015

We investigated the effect of Capsosiphon fulvescens (CFE) and pheophorbide a (PhA) contained in CFE on oxidative stress regarded as a factor for diabetic complication. Streptozotocin (STZ), known as an oxidative stress inducer, was intraperitoneal injected for causing diabetes. After 7 days, CFE (4 and 20 mg/kg body weight) and PhA (0.2 mg/kg body weight) were treated once a day for 9 weeks. After the sacrifice, testis tissues were collected for the experiments. We confirmed that the treatment with CFE and PhA in diabetic animals not only decreased level of lipid peroxidation and serum nitric oxide compared with the diabetes group, but also the activities of glutathione peroxidase and glutathione-S-transferase were restored remarkably. Furthermore the activity of antioxidant enzymes, catalase and superoxide dismutase, were significantly recovered. With these results, our study suggest that CFE containing PhA may prevent seminal glands damages induced by oxidative stress in diabetic condition.

• Journal of Nutrition and Health
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• v.36 no.6
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• pp.570-576
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• 2003

The remarkable change of phenomenon induced by stress increase energy metabolism that can induce many reactive oxygen species (ROS) production. ROS can peroxidize cellular macromolecules including lipid and protein. The object of this study was to investigate whether stress may induce cellular damage by producing ROS and whether vitamin E, as a strong lipid-soluble antioxidant, can protect cells against reactive oxygen species produced by noise and immobilization stress in SD rats. The stress group increased 5-hydroxyindole aceti acid (5-HIAA) , one of the stress hormone, in brain tissue and free fatty acid in plasma. Vitamin I treatment had no effect on 5-HIAA but free fatty acid contents decreased with a fortified vitamin I diet. Furthermore, the body weight of vitamin I-treated rats increased more than that of the stress group. Lipid peroxidation and protein degradation as an index of oxidative damage in brain tissue decreased with the use of the fortified vitamin I diet supplement. The results suggest that vitamin I supplements have a protective effect against noise and immobilization stress-induced oxidative damage in brain tissue.