• Title/Summary/Keyword: 순응형

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Three Sides of Korean Genetically Modified Food Controversies: Global Standards, Right-to-know and Counter-experts (유전자변형식품에 관한 세 가지 논의: 국제기준, 알권리, 대항 전문성)

  • Kim, Hyo-Min;Yeo, Jae-Ryong;Yoo, Soo-Hyung
    • Journal of Science and Technology Studies
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    • v.11 no.2
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    • pp.31-66
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    • 2011
  • The main issue in Korean debates over genetically modified (GM) foods have been government's responsibility to guarantee consumers' right-to-know and make informed choice. Counter-experts' critique over the current regulatory processes based upon substantial equivalence have not been widely publicized. Through interviews and textual analysis, this paper explored three groups' performances in Korean GM food controversies-regulatory scientists, civil society organizations, and counter-experts. Analytic focus was made upon how each of the groups interact with current GM food regulations. While making conflicts with regulatory scientists and their 'discourse of compliance with global standards,' counter-experts were excluded from regulatory processes. This article suggests that the processes and contexts in which counter-experts failed to form strong alliance with other groups need to be examined in order to further understand the specific contours of Korean GM food controversies.

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Comparisons of Adherence, Efficacy and Price between Sitagliptin/Metformin Fixed-dose Combination Tablets and Concomitant Administration of Sitagliptin and Metformin in Type 2 Diabetes Mellitus Patients (제2형 당뇨병 환자에서 시타글립틴과 메트포민 고정 복합제 투여와 단일제 병용간의 복약 순응도, 효과 및 약가에 대한 비교 연구)

  • Park, Ji Hye;Lee, Byung Koo;Kim, Jae Youn;Gwak, Hye Sun
    • Korean Journal of Clinical Pharmacy
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    • v.24 no.3
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    • pp.193-198
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    • 2014
  • Objective: This study was conducted to compare the adherence, clinical and economical utility of fixed-dose combination tablets of sitagliptin/metformin with concomitant administration of sitagliptin and metformin in patients with type 2 diabetes mellitus. Methods: Adherence was measured as the medication possession ratio (MPR) of ${\geq}80%$, and MPR was calculated as the number of total prescription days divided by the total treatment period. Hemoglobin $A_{1C}$ ($HbA_{1c}$) differences between baseline and predetermined periods were analyzed. Proportions of patients who achieved $HbA_{1c}$ less than 6.5% for three or more consecutive times were compared. To evaluate cost-effectiveness, prices of sitagliptin, metformin and sitagliptin/metformin tablets were investigated. Results: More than 90% of patients showed adherence in both groups (92.0% in fixed-dose combination group vs 95.9% in concomitant administration group), and there was no statistically significant difference (P = 0.113). Proportion of patients with HbA1c less than 6.5% for three or more consecutive times tended to be somewhat higher in fixed dose combination group than in concomitant administration group without a statistically significant difference (32.6% vs. 28.0%, P = 0.344). Total price of metformin and sitagliptin was cheaper up to 222 KRW in the case of fixed-dose combination tablets compared to the case of concomitant administration. Conclusion: The sitagliptin/metformin fixed-dose combination tablet had a similar patient adherence and was not significantly different in efficacy to the concomitant administration of each component. In terms of drug prices, fixed-dose combination tablets were cheaper than concomitant administration of each tablet.

Humanism of The Movie by Foucault (푸코로 읽는 영화 <네버 렛 미 고>의 휴머니즘)

  • Choi, Young-Mi;Jo, I-Un
    • The Journal of the Korea Contents Association
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    • v.18 no.1
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    • pp.395-402
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    • 2018
  • This study aims to analyze the film "Never Let Me" by human value which is to be realized in the social structure suppressed by the power of life and the power of discipline in Foucault 's power theory. After 18century having changed monarch power holding the power of life-and-death that enforced corporal punishment, bio-power that corrected body and granted ability suitable discipline to people makes people worked like machine. In control of the bio-power, human achieved safe desire that cure disease and prolong life-span and worked as producer goods. School controls body and make people internalized rule using discipline for working bio-power efficiently. There is differentiation between this movie and the other about human clone. The clones adapt role as organ donator without resistance and there is no conflict between original and copy. Instead of preexistence novel and movie that is set in future, it is a form of past retrospect from the 1970s to 1990s. having emotions, They find independence ego and realize value of life in finite living by depending relation or undergoing loss.

A Study on The Regional Variation of Hypertension Medication Rate (고혈압 약물치료율의 지역 간 변이에 관한 연구)

  • Seok, Hyang-Sook;Kang, Sung-Hong
    • Journal of Digital Convergence
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    • v.11 no.9
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    • pp.255-265
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    • 2013
  • The purpose of this study was to identify the variation factors of hypertension medication rate between regions and to use them as a basic data for establishment of hypertension management business plan which is customized by region. The data were collected from community health survey, National Statistics Office and National Health Insurance Corporation, and were analyzed using the geographically weighted regression. As the result of analysis, the factors that influenced the hypertension medication rate between regions were subjective recognition rate of health level, the rate of medical aid client and the number of health facility per one hundred thousand of population. According to the geographically weighted regression, the total of 230 regional regression models composed of major variables which affected the hypertension medication rate were calculated. However, this study has several limitations that the explanatory power of model is not high and others. Therefore, a follow-up study which is based on the actual data of compliance with hypertension medication will be necessary.

Compliance of Employer and Employee with Occupational Safety Regulation in Small Sized Enterprises of under 5 Employees (5인 미만 사업장의 산업안전 규제 순응 실태)

  • Yi, Kwan-Hyung;Rhee, Kyung-Yong;Sohn, Doo-Ik;Suh, Nam-Kyu;Seo, Kwang-Guk;Oh, Ji-Young
    • Journal of the Korean Society of Safety
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    • v.18 no.4
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    • pp.130-135
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    • 2003
  • This study is planned to investigate the compliance of small sized enterprises of under 5 employees directed by Industrial Safety and Health Act. Occupational safety regulation can be required for employer and employee to comply because that all members of workplace should be involved to protect worker's health. When all members of workplace comply with safety regulation, effectiveness of regulation will be realized as expectation. The study subject is composed of three groups as 501 employers, 501 employees of small sized enterprises of under 5 employees and 107 safety inspectors sampled by stratified random sampling for comparison. Data for analysis is collected from each sample using interview with structured questionnaires. Compliance is measured by 5 point scale composed by 8 sub items such as general perception, understanding, clearness, necessity, relevancy, implementation, penalty, and general compliance of the regulation. Among sub items of employer's compliance, the level of perception of regulation, necessity of regulation, relevancy of penalty are differentiated among three groups. The level of all 8 items of employee's compliance also differentiated among three groups. These results show that strategies for ensuring the same level of compliance among three groups will be needed through education, training and evaluation of regulation and feedback.

Evaluation of Sustained-release Dosage Form with Novel Metformin Salts (새로운 메트포르민 산부가염을 이용한 서방성 제형 평가)

  • Kim, Dong-Wook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.11
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    • pp.7838-7843
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    • 2015
  • In this study, metformin hydrochloride for first choice of type 2 diabetes patient is administered relatively high dose, 1000 to 2000 mg orally once a day, and had very high water solubility, so it make difficult to swallow tablet to requires high amount of sustained release agent. To overcome these challenges, we used novel metformin salts had relatively low water solubility to minimize sustaining excipient for small size of dosage form. six novel metformin salts were synthesized by making metformin free form under reaction with NaOH and adding acid salts. we confirmed metformin stearate had the lowest water solubility and showed half drug release in dissolution study at 12hour. In conclusion, novel metformin salts had low water solubility can be used to reduce the size of sustained metformin tablet for improving patient compliance.

The Survey on the Preferences for the New Child Dosage Forms of Oriental Herbal Medicine (신제형의 소아 약물 순응도 조사;기존의 제재와 비교하여 복용의 간편성, 맛의 개선도, 운반 및 저장의 편의성 포함)

  • Seo, Jung-Min;Yun, Hye-Jin;Kim, Sang-Chan;Hwang, Sun-Yi;Jee, Seon-Young;Cho, Dong-Hee;Son, Ji-Young;Baek, Jung-Han
    • The Journal of Pediatrics of Korean Medicine
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    • v.21 no.3
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    • pp.11-19
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    • 2007
  • Objective Medication is one the most important things in treatment for children, but prescribing traditional herbal medicine for them is very difficult. Therefore, we made 4 new forms of oriental herbal medicine that has a better taste, smell, and color. These new forms also have a texture that make medicine easier to chew. Methods We made up a question of 20 children visiting $\bigcirc\;\bigcirc$ university hospital. Results and Conclusions 1. Children preferred liquid or pill type of herbal medicine. 2. The preference sensory test of the traditional medicine and new form of medicine had not much difference. 3. On the test for preferences, it resulted as they liked the 4th form of new medicine which was with little bit more of sweet and sour taste, and the 3rdformwithnewcolors. 4. They hated traditional herbal medicine of the taste, smell, color, sensation of texture of material.

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A Study on Health Behaviors of the Young Adults and the Elderly with Hypertension: A Secondary Analysis of the 2018 Korea Health Panel Data (고혈압이 있는 청장년층과 노년층의 건강행위 분석: 2018년 한국의료패널조사 자료활용)

  • Keum Sook, Kim
    • Journal of Industrial Convergence
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    • v.20 no.11
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    • pp.141-148
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    • 2022
  • The purpose of this study was to investigate the health behavior performance between the young adults and the elderly with hypertension. The research data were analyzed using 2018 Korea Medical Panel data. The subjects of this study were 3,117 persons without disabilities or activity disorders among those diagnosed with hypertension. As a result of the study, first, it was found that the medical utilization rate and drug adherence were high overall. Second, the average body mass index(BMI) and obesity over 25 kg/m2 were found to be higher among the young adults. Third, smoking and drinking were higher in young adults in terms of experience and smoking and alcohol consumption. Fifth, the subjective health status was found to be perceived more positively by the young adults. Based on the results of this study, it is necessary to raise awareness of the need for customized health care from a young age and to develop sustainable and effective programs.

ELECTRON MICROSCOPIC STUDY OF SLOWLY ADAPTING PERIODONTAL MECHANORECEPTIVE PRIMARY AFFERENT FIBERS WITHIN THE SUBNUCLEUS ORALIS OF THE CAT (서순응형 치근막 일차구심성 신경섬유 종말부의 Subnucleus oralis에서의 시냅스 양상에 관한 전자현미경적 연구)

  • Kim, Moo-Jung;Bae, Yong-Chul;Kim, Chin-Soo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.15 no.4
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    • pp.281-301
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    • 1993
  • It was revealed that the morphology and projection pattern of terminal arbors from single primary afferent are different among distinct fiber types, functional types and the different subdivision of trigeminal sensory nucleus complex(TSNC). But it was not identified the ultrastructural morphology and synaptic connections of terminal arbors from each primary afferent within TSNC. So we employed the intra-axonal horseradish peroxidase(HRP) injection technique to define the terminal arbors of primary afferent fiber from slowly adapting mechanoreceptors in the periodontal ligament of the cat, and examined 66 labeled terminal arbors within the rostrodorsomedial part(Vo.r) of the trigeminal nucleus oralis, electromicroscopically with 90nm serial sections. All the boutons labelled with HRP contained clear, spherical and uniform sized synaptic vesicles(diameter : $47.66{\pm}3.58nm$ ). Most of the labelled boutons were boutons en passant type and they were connected by unmyelinated axonal strand. In which neurofilament and microtubule was not developed but occasionally contained synaptic vesicle in contrast to the myelinated axon. The size of the labelled bouton was relatively small(long diameter : $1.46{\pm}0.24{\mu}m$, short diameter $0.85{\pm}0.26{\mu}m$, average diameter $1.15{\pm}0.24{\mu}m$) and the shape of which varied from dome to elongated shape, but scalloped glomerulus shape was not developed. Each primary ending in Vo.r made synapse with one or two neuronal propiles(average : $1.11{\pm}0.31$), of which, 89.4% of labelled boutons made synapse with only one neuronal pro pile, the remainder, 10.6% of labelled boutons, made synapse with two neuronal propile. So characteristically they made very simple synapse. Most of labelled boutons(80.03%) made asymmetrical synapse only with dendritic shaft or spine, and 6.1% of labelled boutons received symmetrical synapse from pleomorphic vesicle containing axonal ending(p-ending). So presynaptic inhibiton was relatively scarce. Synaptic triad, in which a p-ending is presynaptic both pre-and post-synaptic element of the axo-dendritic contact from the labelled primary ending was not observed.

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Multi-perspective process modeling (프로세스 모델링을 위한 개념적 틀)

  • 권태형;연광호;최은희
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1995.09a
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    • pp.233-248
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    • 1995
  • 조직변혁(OT:Organizational Tranformation)은 Macro(거시적), Micro(미시 적), Meso(중간적) 관점과 사회적, 기술적 관점을 혼합하여 전체적으로 6가 지의 가능성을 갖는 영역을 생성할 수 있다. 최근 조직 설계와 관련된 많은 연구들은 급변하는 환경에 대한 조직의 반응으로써 기능 중심의 조직설계 대신 Meso관점의 프로세스 중심의 조직 설계를 통한 조직 변혁을 제안해 왔다. 프로세스 재설계 혹은 리엔지니어링과 같은 용어로 등장하는 이 관점 은 서로 다른 연구분야 사이의 상호 연계적 적용을 증가시키고 적절한 자원 할당 및 혼합을 가능하게 함으로써 고객요구와 경쟁력 같은 외부요구사항과 내부적 생산성등을 연계시키고자 한다. 프로세스 모델링은 프로세스 중심의 조직 설계를 통한 조직 변혁의 중요한 도구로 사용될 수 있다. 조직 변혁의 6개 영역과 프로세스의 구성요소 중 일부에만 관심을 갖는 기존의 프로세스 모델링 관점들-기능적 업무(task) 중심의 '기능 관점', 행위적 논리(logic) 중 심의 '행위 관점', 조직적 역할 (roles) 중심의 '조직 관점'-을 반영한 프로세 스 모델은 프로세스 수행목적의 표현과 프로세스 재설계의 기회 발견에 한 계가 있다. 본 연구에서는 프로세스 모델링 기법에 의해 표현되어야 하는 프 로세스 구성요소들을 5W1H를 기준으로 분류하고, 기존 모델링 관점들이 가 지는 한계점의 해결을 위해 두 가지의 새로운 프로세스 모델링 관점-프로세 스 목적과 가치를 표현하는 '정보 관점', 프로세스의 측정에 대한 계량적 정 보를 표현하는 '측정 관점'-을 제시하고, 조직 변혁이 여러 관점들의 통합을 지원하는 프로세스 모델링을 위한 개념적 틀(MPPM)과 프로세스 모델에서 표현되어야 하는 프로세스 구성요소들을 제시하였다.용자 만족도가 보다 높은 것으 로 나타났다. 할 수 있는 효율적인 distributed system를 개발하는 것을 제시하였다. 본 논문은 데이타베이스론의 입장에서 아직 정립되어 있지 않은 분산 환경하에서의 관계형 데이타베이스의 데이타관리의 분류체계를 나름대로 정립하였다는데 그 의의가 있다. 또한 이것의 응용은 현재 분산데이타베이스 구축에 있어 나타나는 기술적인 문제점들을 어느정도 보완할 수 있다는 점에서 그 중요성이 있다.ence of a small(IxEpc),hot(Tex> SOK) core which contains two tempegatlue peaks at -15" east and north of MDS. The column density of HCaN is (1-3):n1014cm-2. Column density at distant position from MD5 is larger than that in the (:entral region. We have deduced that this hot-core has a mass of 10sR1 which i:s about an order of magnitude larger those obtained by previous studies.previous studies.업순서들의 상관관계를 고려하여 보다 개선된 해를 구하기 위한 연구가 요구된다. 또한, 준비작업비용을 발생시키는 작업장의 작업순서결정에 대해서도 연구를 행하여, 보완작업비용과 준비비용을 고려한 GMMAL 작업순서문제를 해결하기 위한 연구가 수행되어야 할 것이다.로 이루어 져야 할 것이다.태를 보다 효율적으로 증진시킬 수 있는 대안이 마련되어져야 한다고 사료된다.$\ulcorner$순응$\lrcorner$의 범위를 벗어나지 않는다. 그렇기

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