• The Journal of the Acoustical Society of Korea
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• v.19 no.7
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• pp.66-76
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• 2000

Acoustic performance of loudspeakers for sound reproduction has been qualitatively evaluated by using the listening test by juries in the development and final evaluation stages. However, the subjective evaluation method has many problems in the viewpoint of reliability and repeatability that are mainly related to the jury performance, as well as time and economy. In this reason, objective techniques should be tried to evaluate the acoustic performance of loudspeakers as well as the conventional subjective test. The object of this study is to find if there is any correlation between the statistically treated in test results and the measured results based on the loudness of reproduced sound signals. For the four-step statistical analysis, the analysis of variance (ANOVA) and Tukeys method are employed for dealing with the data from the listening test. For the objective evaluation, Zwickers loudness considering the human hearing characteristics is calculated for the measured sound signal emitted from each loudspeaker and the objective ratings such as fidelity rating (FR) and softness rating (SR) is suggested. The correlation between two ratings has been demonstrated for an actual set of loudspeakers using FR, SR and correlation coefficient. The method in this study can be useful in statistically evaluating commercial or prototype loudspeakers without using very time-consuming and expensive subjective testing.

• Journal of Life Science
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• v.27 no.3
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• pp.361-369
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• 2017

Mitochondrial homeostasis is tightly regulated by two major processes: mitochondrial biogenesis and mitochondrial degradation by autophagy (mitophagy). Research in mitochondrial biogenesis in skeletal muscle in response to endurance exercise training has been well established, while the mechanisms regulating mitophagy and the relationship between mitochondrial biogenesis and degradation following endurance exercise training are not yet well defined. Studies have demonstrated that endurance exercise training increases the expression levels of mitochondrial biogenesis-, dynamics-, mitophagy-related genes in skeletal muscle. However, the increased levels of mitochondrial biogenesis marker proteins such as Cox IV and citrate synthase, by endurance exercise training were abolished when autophagy/mitophagy was inhibited in skeletal muscle. This suggests that both autophagy/mitophagy plays an important role in mitochondrial biogenesis/homeostasis and the coordination between the opposing processes may be important for skeletal muscle adaptation to endurance exercise training to improve metabolic function and endurance exercise performance. It is considered that endurance exercise training regulates each of these processes, mitochondrial biogenesis, fusion and fission events and autophagy/mitophagy, ensuring a relatively constant mitochondrial population. Exercise training may also have contributed to mitochondrial quality control which replaces old and/or unhealthy mitochondria with new and/or healthy ones in skeletal muscle. In this review paper, the molecular mechanisms regulating mitochondrial biogenesis and mitophagy and the coordination between the opposing processes is involved in the cellular adaptation to endurance exercise training in skeletal muscle will be discussed.

• Atmosphere
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• v.13 no.4
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• pp.57-70
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• 2003

The National Center for Intensive Observation of Severe Weathers (NCIO) as a part of METRI's principal project "Korea Enhanced Observing Period; KEOP" was established at Haenam Weather Observatory in order to effectively monitor and observe heavy rainfall in summer, which is essential for the identification of the structure and evolution mechanism of mesoscale severe weather system. The intensive field-based experiments in 2002 within southwestern Korea toward various meteorological phenomena ranging from heavy rainfall to snowfall were conducted in collaboration with KMA(Korea Meteorological Administration) and universities. In this study, preliminary analysis results using intensive observation data obtained from these experiments are presented together with the introduction of NCIO and its operational structure.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.1614-1618
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• 2007

분포형 수문모형은 유역을 격자단위로 세분화하여 매개변수를 부여하고, 증발산, 침투, 지표면유출, 중간유출, 지하수유출, 하도흐름 등 여러 가지 수문요소를 해석하는 종합적인 수문모형이다. 지표면에 내린 강우의 증발 및 침투, 유출은 토양수분의 함량에 크게 의존하게 된다. 따라서 토양수분에 대한 적절한 모의가 분포형 수문모형의 정확도를 좌우하는 핵심이라 할 수 있다. 토양수분은 식물의 생장 및 가용수자원 산정 등에 있어서 중요한 요소로서 토양층 상부의 수 미터 내에 존재하는 수분의 양을 일컫는다. 토양수분의 공간적 시간적 특성들은 증발, 침투, 지하수 재충전, 토양침식, 식생분포 등을 지배하는 매우 중요한 요소라 할 수 있다. 강우로 인한 지면과 지표하에서의 순간적인 포화공간의 형성 및 유출의 생성을 포함하는 과정과 증발산 등은 모두 비포화대(vadose zone) 혹은 토양층에서의 토양수분의 함량에 크게 의존하게 된다(이가영 등, 2005) 본 연구에서는 토양수분에 대한 정밀측정 자료가 있는 설마천 유역 범륜사 사면에 대하여 분포형 수문모형의 토양수분 해석 능력을 평가하고자 하였다. 토양수분 모의에 사용된 격자기반의 분포형 수문모형은 미공병단에서 개발한 GSSHA(USACE, 2006) 모형이다. 모형의 입력자료는 정밀토양도와 현장측정에 의한 토양매개변수를 반영하여 구축하였고, 강우 및 기상자료는 2003년 1월 1일 ${\sim}$ 2004년 12월 31일의 1시간 자료를 이용하였다. 모의기간 중 2003년은 초기 토양수분값 등 초기조건의 영향을 줄이기 위한 웜업 (Warm-up)기간으로 설정하였고, 2004년의 모의결과를 토양수분 관측값과 비교하였다.업지역, 상업지역 등과 같이 지형적 특성에 따른 유량측정망을 구축하는 것이다.의 의사결정 지원 도구가 될 것이다. 따라서, 본 연구에서는 도시유역의 물순환 해석을 위한 일련의 과정, 즉 자료의 조사 및 취득에서부터 물순환 해석 모형을 이용한 정량적 현황파악, 물순환 개선 기법 및 평가를 수행함에 있어 주요 착안점 및 실무에서의 기술적 가이드를 제공하고자 하였으며, 보다 세밀한 도시유역의 물순환 해석을 위하여 우리나라와 일본에서 적용이 활발한 물리적 기반의 분포형 모형(WEP, SHER, SWMM)의 적용사례를 통하여 국내 도시하천의 물순환 해석에 활용함에 있어서의 실질적인 적용절차 등을 제시하고자 하였다. 한다.호강유역의 급격한 수질개선을 알 수 있다.世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와 동년대에 동일한 목적으로 찬술되었음을 알 수 있다. $\ulcorner$경상도실록지리지$\lrcorner$(慶尙道實錄地理志)에는 $\ulcorner$세종실록$\lrcorner$(世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와의 비교를 해보면 상 중 하품의 통합 9개소가 삭제되어 있고, $\ulcorner$동국여지승람$\lrcorner$(東國與地勝覽) 에서는 자기소와 도기소의 위치가 완전히 삭제되어 있다. 이러한 현상은 첫째, 15세기 중엽 경제적 태평과 함께 백자의 수요 생산이 증가하자 군신의 변별(辨別)과 사치를 이유로 강력하게 규제하여 백자의 확대와 발전에

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.1063-1069
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• 2007

우리나라의 하천환경은 1990년대 이전의 산업화와 인구증가를 수반한 고도성장기를 거치면서 이수성 및 치수성만을 강조하며 개수되고 관리되었다. 그 결과 하천은 획일적인 단면과 저수로 및 제방이 콘크리트화되면서 하천의 자정능력은 감소되었고, 하천을 중심으로 생활하는 동물들의 서식처 기능을 상실해 하천생태계가 위협받고 있다. 하천공사에 자연형 하천공법이 도입되기 시작하여 자연형 하천공사가 이루어지고 있지만 생태환경의 관점보다는 조경 및 경관적, 그리고 위락적인 관점에서 공원화에 주안점을 두고 있어 하천의 생태적 특성의 반영이 부족하다는 평가를 듣고 있는 실정이다. 따라서 본 연구에서는 향후의 하천공법이 자연적 기능들 중 생물서식처 기능을 보다 깊이 다루어야 한다는 필요성을 고려하여, 먹이사슬의 최상위에 있을 뿐만 아니라 하천환경의 건강도를 판단할 수 있는 수환경의 지표종이라 불리는 수달(Lutra lutra)을 대상으로 배설물에 의한 출현빈도와 하천환경 요인들에 대한 상관관계를 분석하여 수달 서식지 복원을 위한 하천정비의 기초자료를 제공하는 데 그 목적이 있다. 이를 위해 현재 수달이 서식하고 있는 섬진강 지류인 서시천을 연구 대상지점으로 하여 5개 구간을 선정하였으며, 각 구간에 대한 계절별 수달의 배설물 분포를 조사하여 출현빈도를 나타내었다. 또한 먹이, 지형, 식생, 기상인자를 포함한 하천환경 요인들에 대한 자료를 각 계절별로 구축하였으며, 이를 수달의 출현빈도와의 상관관계를 조사하는데 활용하였다. 본 연구의 결과는 환경 기술적으로는 멸종위기종의 복원, 사회경제적으로는 하천정비사업의 방향제시 등의 기대효과를 가져올 수 있으리라 생각되며 분석된 인자들은 수달 서식지를 위한 하천정비의 기초자료에 유용할 것으로 보인다.따른 유량측정망을 구축하는 것이다.의 의사결정 지원 도구가 될 것이다. 따라서, 본 연구에서는 도시유역의 물순환 해석을 위한 일련의 과정, 즉 자료의 조사 및 취득에서부터 물순환 해석 모형을 이용한 정량적 현황파악, 물순환 개선 기법 및 평가를 수행함에 있어 주요 착안점 및 실무에서의 기술적 가이드를 제공하고자 하였으며, 보다 세밀한 도시유역의 물순환 해석을 위하여 우리나라와 일본에서 적용이 활발한 물리적 기반의 분포형 모형(WEP, SHER, SWMM)의 적용사례를 통하여 국내 도시하천의 물순환 해석에 활용함에 있어서의 실질적인 적용절차 등을 제시하고자 하였다. 한다.호강유역의 급격한 수질개선을 알 수 있다.世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와 동년대에 동일한 목적으로 찬술되었음을 알 수 있다. $\ulcorner$경상도실록지리지$\lrcorner$(慶尙道實錄地理志)에는 $\ulcorner$세종실록$\lrcorner$(世宗實錄) $\ulcorner$지리지$\lrcorner$(地理志)와의 비교를 해보면 상 중 하품의 통합 9개소가 삭제되어 있고, $\ulcorner$동국여지승람$\lrcorner$(東國與地勝覽) 에서는 자기소와 도기소의 위치가 완전히 삭제되어 있다. 이러한 현상은 첫째, 15세기 중엽 경제적 태평과 함께 백자의 수요 생산이 증가하자 군신의 변별(辨別)과 사치를 이유로 강력하게 규제하여 백자의 확대와 발전에 걸림돌이 되었다. 둘째, 동기(銅器)의 대체품으로 자기를 만들어 충당해야할 강제성 당

• Land and Housing Review
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• v.5 no.4
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• pp.259-269
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• 2014

After global financial crisis, the ratio of household debt to GDP was decreasing in other advanced countries such as the U.S., and the U.K. and so on. But, in Korea, household debt (of which residential mortgage loan account for a large part) ratio is still increasing. This paper focuses on the scale and characteristics of households in negative housing equity (those are called House-poors in Korea), and also the socio-economic backgrounds of the formation process. In financial perspective, the problem of negative housing equity depends on financial debt repayment capability. We used DSR (Debt Service Ratio) and LTA (Loan to Asset ratio) as financial indicators to evaluate the debt repayment capability. The critical value of DSR is assumed as 40%, and LTA 100%. The socio-economic backgrounds of the House-poors are as follows : increasing households debt dependency, over lending competition of financial institutions and unreasonable loan in household economy, instability of real estate market, week regulation on mortgage loan. Finally, this paper suggests some implications about the range and the target of public intervention.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.1
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• pp.41-49
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• 2018

This study is to analyze and evaluate water resource development potential in North Korea. The study was conducted to analyze selected potential hydropower as an indicator to evaluate water resource development potential. Potential hydropower means theoretical value about the potential capacity of river. It is used to evaluate the amount of development through the hydropower generation. For calculating potential hydropower, monthly average and annual average of rainfall for each river basin were calculated by using the data of 27 rainfall stations in North Korea. As a result of the calculation of theoretical potential hydropower by rainfall in the seven major basins in North Korea, the Aprok River basin was analyzed to be the largest with $7,562.2{\times}10^3kW$. The efficiency and utilization rate of theoretical potential hydraulic power in South Korea and North Korea was 42.3% and 36.2%, respectively. The Daedong River basin's potential hydropower utilization rate is 12.3%, which is the lowest in North Korea. In the case of Daedong River basin, more than 40% of the total population is inhabited, so demand for water and electricity is expected to be the largest. Therefore, the Daedong River basin is considered as a priority area for water resource development. The results of this study are expected to be used as basic data for future water resource development projects and research activities in North Korea.

• Journal of Genetic Medicine
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• v.8 no.1
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• pp.28-34
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• 2011

Most clinicians understand clinical trials as the evaluation process for new medicine before their use. However, clinical trials can also be applied to laboratory diagnostic tests (LDTs) to verify diagnostic accuracy and efficacy before their clinical laboratory implementation for patients. The clinical trial of LDT has two distinctive characteristics that are different from the case of pharmaceuticals and thus worth special consideration. One of them is the level of evidence. The well-designed randomized controlled trials (RCTs) are known to provide the best evidence to prove the clinical efficacy of any pharmaceutical products. However, RCTs lose practicality when applied to LDTs due to various issues including ethical complications. For this reason, comparative study format is considered more feasible approach for LDTs. In addition pharmaceuticals and LDTs are different in that the user's intervention is not required for the former but critical to the latter. Moreover, in the case of pharmaceuticals, end-products are produced by manufacturers before being used by clinicians. However, in LDTs, once reagents and instruments are provided by manufacturers, they are first utilized by clinical laboratories to produce test results in order for clinicians to use them later. In other words, when it comes to LDTs, clinical laboratories play the role of manufacturers, providing reliable test results with improved quality assurance. Considering the distinctive characteristics of LDTs, we would like to offer detailed suggestions to successfully perform clinical trials in LDTs, which include analytical performance measures, clinical test performance measures, diagnostic test accuracy measures, clinical effectiveness measures, and post-implementation surveillance.

• Journal of Korean Society of Environmental Engineers
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• v.34 no.6
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• pp.430-437
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• 2012

In order to obtain information on the design parameters of the horizontal laterals in floodplain filtration, laboratory-scale sand-box experiments were performed where the head distributions on the laterals and the groundwater profiles were measured according to the change in parameters including lateral diameter, hydraulic conductivity of the sand, water level at the well and raw-water supply rate. Measured data were analyzed using a numerical code in order to identify the discharge intensity distribution along the laterals. It was observed from the result that the lowering of the water level at the well had minimal adverse effect on the performance of the floodplain filtration. Results also elucidated that the low conveyance of the laterals to transmit the filtrate was compensated and supplemented by a natural augmentation in horizontal conveyance through the aquifer when the raw-water supply rate exceeded the adequate recovery rate. With this mechanism, the water quality is expected to improve further since the travel distance through the aquifer is amplified. Based on these findings it can be suggested that the diameter of the lateral used in the floodplain filtration may be smaller than those in riverbank/bed filtration. It was also found that the ratio between the head loss occurring in a lateral and the total head loss in the floodplain filtration was proportional to the exit velocities of the laterals, which may be used to design and/or evaluate the lateral in floodplain filtration.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.42 no.3
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• pp.303-309
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• 2016

The human skins had a lot of changes as aging. The synthesis of collagens and elastic fibers were reduced and the expression of matrix metalloproteinase (MMPs) was increased in the dermis. These changes have been known to be responsible for skin wrinkle formation. In this study, we tried to develop pre-indicator of inner skin aging, and investigated the effect of the cream product containing Gynostemma pentaphyllum gypenoside fraction (Gynostemma pentaphyllum gypenoside cream). 21 ~ 34 years old 52 Korean female volunteers without crow's feet were chosen for this clinical study. The starting point of inner skin aging was confirmed through dermal density measurement, even though outside skin wrinkles were not observed. In addition, 4 and 8 weeks treatment of G. pentaphyllum gypenoside cream significantly increased age-related reduction of dermal density. These results suggest that the evaluation of dermal density can be used as pre-indicator of skin aging. Furthermore, G. pentaphyllum gypenoside fraction is a potential anti-wrinkle agent for prevention and treatment of skin aging.