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Effects of Dietary Supplementation of Domestic Skullcap (Scutellaria baicalensis) Extracts on Performance, Immune Response and Intestinal Microflora in Broiler Chicken (국내 자생 황금 추출물의 첨가 급여가 육계의 생산성, 면역 기능 및 장내 균총 변화에 미치는 영향)

  • Kwon, H.S.;Kim, J.Y.;Kim, J.S.;Lee, B.K.;Lee, S.Y.;Lee, W.S.;Ahn, B.K.;Kim, E.J.;Kang, C.W.
    • Korean Journal of Poultry Science
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    • v.35 no.4
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    • pp.351-359
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    • 2009
  • This study was carried out to investigate dietary effects of extracts of Skullcap (Scutellaria baicalensis) (SCE) grown in Korea on growth performance, immune and physiological responses in broiler chickens. Total of seven-hundred fifty 1-d-old Ross male broiler chicks were divided into five groups and fed control diets (antibiotics medicated or non-medicated commercial diets) or each experimental diet (non-medicated diets containing 0.1, 0.3 or 0.5% SCE) for 5 weeks. The body weight gain and feed conversion rate in the groups fed diets containing 0.1% or 0.3% SCE were significantly improved as compared with those of non-medicated control group (P<0.05). The levels of total cholesterol and HDL-cholesterol of blood were not influenced by feeding the SCE. The average antibody titers against NDV and IBV in the groups fed diets containing SCE were significantly increased compare to those of the control groups (P<0.05). The number of coli form bacteria was significantly reduced by feeding 0.3% or 0.5% SCE as compared to that of non-medication control (P<0.05). The results demonstrated that the SCE used in this study modulated humoral immunity and the profiles of cecal microflora and thus can be used as a potential alternative substance to replace antibiotics for feeding broiler chicks.

Effect of Recombinant CagL Immunization on the Gastric Diseases Induced by Helicobacter pylori in Mongolian gerbils (CagL 재조합 단백질 접종후에 Mongolian gerbil에서 나타나는 Helicobacter pylori 감염에 대한 반응)

  • Bak, Eun-Jung;Jang, Sung-Il;Choi, Yun-Hui;Kim, Jin-Moon;Kim, Ae-Ryun;Kim, Ji-Hye;Woo, Gye-Hyeong;Yoo, Yun-Jung;Lee, Sung-Haeng;Cha, Jeong-Heon
    • Korean Journal of Microbiology
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    • v.48 no.2
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    • pp.109-115
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    • 2012
  • Helicobacter pylori is an important factor of chronic gastritis, digestive ulcer, and stomach cancer. CagL, a virulence factor of H. pylori, is well-known as a pilus protein which acts as adhesion to host cell and a component of Type 4 secretion system. In this study, we evaluated the protective response of recombinant CagL protein (rCagL) using Mongolian gerbil animal model for H. pylori infection. The cagL gene was cloned from 26695 H. pylori followed by over-expression and purification of the protein in E. coli. Mongolian gerbils were immunized with rCagL protein mixed with aluminum adjuvant via intramuscular injections once a week during 4 weeks. At a week after the last immunization, the Mongolian gerbils were administrated with H. pylori 7.13 strain into the stomach and sacrificed to measure antibody titer on rCagL by ELISA and bacterial colonization in the stomach, and to examine the histopathological changes and cytokine expression at 6 week after challenge. Antibody titers on recombinant protein were significantly increased from a week after the first immunization. There was no significant change of the number of bacterial colony between control group and immunized group. The relative stomach weight was significantly decreased in immunized group, but the significant change of histopathological assessment was not observed in the stomach. Cytokine expression such as IL-$1{\beta}$ and KC also was not significantly different between control and immunized groups. These results indicate that rCagL could effectively induce the formation of the specific IgG antibodies. However, bacterial colonization and histopathological lesions could not be inhibited by the immunization in the stomach, indicating not enough protection against H. pylori infection. We consider that along with CagL other adequate antigens could be needed stimulating immune response and inducing protective effects against gastric disease, and also a better adjuvant could be considered.

Development of a Ranging Inspection Technique in a Sodium-cooled Fast Reactor Using a Plate-type Ultrasonic Waveguide Sensor (판형 웨이브가이드 초음파 센서를 이용한 소듐냉각고속로 원격주사 검사기법 개발)

  • Kim, Hoe Woong;Kim, Sang Hwal;Han, Jae Won;Joo, Young Sang;Park, Chang Gyu;Kim, Jong Bum
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.25 no.1
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    • pp.48-57
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    • 2015
  • In a sodium-cooled fast reactor, which is a Generation-IV reactor, refueling is conducted by rotating, but not opening, the reactor head to prevent a reaction between the sodium, water and air. Therefore, an inspection technique that checks for the presence of any obstacles between the reactor core and the upper internal structure, which could disturb the rotation of the reactor head, is essential prior to the refueling of a sodium-cooled fast reactor. To this end, an ultrasound-based inspection technique should be employed because the opacity of the sodium prevents conventional optical inspection techniques from being applied to the monitoring of obstacles. In this study, a ranging inspection technique using a plate-type ultrasonic waveguide sensor was developed to monitor the presence of any obstacles between the reactor core and the upper internal structure in the opaque sodium. Because the waveguide sensor installs an ultrasonic transducer in a relatively cold region and transmits the ultrasonic waves into the hot radioactive liquid sodium through a long waveguide, it offers better reliability and is less susceptible to thermal or radiation damage. A 10 m horizontal beam waveguide sensor capable of radiating an ultrasonic wave horizontally was developed, and beam profile measurements and basic experiments were carried out to investigate the characteristics of the developed sensor. The beam width and propagation distance of the ultrasonic wave radiated from the sensor were assessed based on the experimental results. Finally, a feasibility test using cylindrical targets (corresponding to the shape of possible obstacles) was also conducted to evaluate the applicability of the developed ranging inspection technique to actual applications.

Effects of shoulder rotation according to stance posture and plane of motion on EMG response of shoulder rotator cuff and Trunk muscles. (스탠스 자세와 운동면의 차이에 따른 위팔어깨관절의 돌림운동이 어깨돌림근군과 몸통근군의 근전도 반응에 미치는 영향)

  • Kim, Ki-Hong;Cho, Sang-Woo;Jeong, Hwan-Jong;Kim, Ki-Hong
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.3
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    • pp.914-924
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    • 2018
  • The purpose of this study is to provide the basic data for the shoulder strengthening exercise by analyzing the% MVIC of the muscle activity in the shoulder rotator cuff by the difference of the stance posture and the anatomical plane. 8male subjects were randomly assigned to perform the shoulder rotation exercise 10 times on the frontal plane, the horizontal plane, the sagittal plane and the two legs stance posture, the one leg stance posture, the lunge posture. Measured muscle activity of supraspinatus, infraspinatus, teres minor, anterior deltoid, rectus abdominis, erector supinea, pectoralis major, lattisimus dorsi during exercise. A repetitive one-way ANOVA was performed using the SPSS 22.0 statistical program. First, during the external rotation on the frontal plane, the erector spinea was higher in the lunge posture than in the two legs stance posture and the one leg stance posture, And during the internal rotation on the frontal plane, the muscle activity of suprapinatus was higher in one leg stance posture than in the two legs stance posture and more so in the lunge posture. Second, during the external rotation on the horizontal plane, the muscle activity of deltoid anterior was higher in the one legs stance posture and in the lunge posture than in the two legs stance posture, and during the internal rotation on the horizontal plane, the muscle activity of infraspinatus was higher in the lunge posture than in the two legs stance posture and one leg posture, and the muscle activity of pectoralis major was higher in two leg stance posture than in the one legs stance posture and more so in the lunge posture. Third, during the external rotation on the sagittal plane, muscle activity of rectus abdominis was higher one leg stance posture in the lunge posture than in two leg stance posture. During the internal rotation on the sagittal plane, muscle activity of supraspinatus was higher one leg stance posture in the lunge posture than in two leg stance posture. And muscle activity of infraspinatus was higher in the lunge posture than in two leg stance posture, one leg stance. And muscle activity of Rectus abdominis was higher in the lunge posture and one leg stance posture than in the two legs stance posture. And muscle activity of Erector spinea was higher in the two legs stance postur and lunge posture than in the one leg stance posture. In conclusion, the differences in stance and shoulder anatomy have different effects on the muscle activity of the shoulder rotator exercises, and this is expected to be a more positive exercise program when applied to the shoulder strengthening exercise program.

Settling Characteristics of Natural Loess Particles in Seawater (해수 중에서 자연상태 황토입자의 침강특성)

  • KIM Sung-Jae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.6
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    • pp.706-712
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    • 1999
  • PSD (particle size distribution) for 2,000 mg/$\ell$ natural loess in seawater showed normal distribution cure at 0 minute settling time, accompanying with very large particle distribution range with its mean particle diameter of 31.6 $\mu$m and coencient of variance of $72.6\%$, With elapsed time it showed that the PSD was rapidly changed from normal distribution cure to abnormal distribution curve, steepened the right-hand side of it and its coefficient of variance was getting increased because of rapid settling of large size particles, Cumulative weight distribution showed that 2,000 mg/$\ell$ natural loess in seawater was almost $100\%$ constituted of particles bigger than 20 $\mu$m in diameter. Ratio of $V_s/(D_{bm})^{1/2}$ for loess particles in seawater was increased with increase of particle size in geometrical progression. Almost all loess particles in seawater had Stokes settling velocity not less than 2,255 times of Brownian diffusion coefficient, There was almost to EDL (about 0.4 nm) around natural loess particles in seawater, Thus, there was always LVDW attractive force between loess particles approaching each other in seawater, and almost no EDL repulsive force. Loess particles were not always in the condition of easy floe formation. Concentration of natural loess in seawater increasing from 400 mg/$\ell$ to 10,000 mg/$\ell$, characteristics of the settling was changed from Type I settling (discrete settling) to Type II settling (flocculation settling). PVD (particle volume distribution) showed that natural loess particles in seawater were largely constituted of two types of particles, such as rapidly settling particles and suspended and dispersed particles for a long time. Amount of the latter was much less than that of the former.

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Magnetic Properties of Electroless Co-Mn-P Alloy Deposits (무전해 Co-Mn-P 합금 도금층의 자기적 특성)

  • Yun, Seong-Ryeol;Han, Seung-Hui;Kim, Chang-Uk
    • Korean Journal of Materials Research
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    • v.9 no.3
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    • pp.274-281
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    • 1999
  • Usually sputtering and electroless plating methods were used for manufacturing metal-alloy thin film magnetic memory devices. Since electroless plating method has many merits in mass production and product variety com­pared to sputtering method, many researches about electroless plating have been performed in the United State of America and Japan. However, electroless plating method has not been studied frequently in Korea. In these respects the purpose of this research is manufacturing Co-Mn-P alloy thin film on the corning glass 2948 by electroless plating method using sodium hypophosphite as a reductant, and analyzing deposition rate, alloy composition, microstructure, and magnetic characteristics at various pH's and temperatures. For Co-P alloy thin film, the reductive deposition reaction 0$\alpha$urred only in basic condition, not in acidic condition. The deposition rate increased as the pH and temperature increased, and the optimum condition was found at the pH of 10 and the temperature of $80^{\circ}C$. Also magnetic charac­teristics was found to be most excellent at the pH of 9 and the temperature of $70^{\circ}C$, resulting in the coercive force of 8700e and the squareness of 0.78. At this condition, the contents of P was 2.54% and the thickness of the film was $0.216\mu\textrm{m}$. For crystal orientation, we could not observe fcc for $\beta$-Co. On the other hand,(1010), (0002), (1011) orientation of hcp for a-Co was observed. We could confirm the formation of longitudinal magnetization from dominant (1010) and (1011) orientation of Co-P alloy. For Co-Mn-P alloy deposition, coercive force was about 1000e more than that of Co P alloy, but squareness had no difference. For crystal orientation, (l01O) and (lOll) orientation of $\alpha$-Co was dominant as same as that of Co- P alloy. Likewise we could confirm the formation of longitudinal magnetization.

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Studies on Changes in the Hydrography and Circulation of the Deep East Sea (Japan Sea) in a Changing Climate: Status and Prospectus (기후변화에 따른 동해 심층 해수의 물리적 특성 및 순환 변화 연구 : 현황과 전망)

  • HOJUN LEE;SUNGHYUN NAM
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.28 no.1
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    • pp.1-18
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    • 2023
  • The East Sea, one of the regions where the most rapid warming is occurring, is known to have important implications for the response of the ocean to future climate changes because it not only reacts sensitively to climate change but also has a much shorter turnover time (hundreds of years) than the ocean (thousands of years). However, the processes underlying changes in seawater characteristics at the sea's deep and abyssal layers, and meridional overturning circulation have recently been examined only after international cooperative observation programs for the entire sea allowed in-situ data in a necessary resolution and accuracy along with recent improvement in numerical modeling. In this review, previous studies on the physical characteristics of seawater at deeper parts of the East Sea, and meridional overturning circulation are summarized to identify any remaining issues. The seawater below a depth of several hundreds of meters in the East Sea has been identified as the Japan Sea Proper Water (East Sea Proper Water) due to its homogeneous physical properties of a water temperature below 1℃ and practical salinity values ranging from 34.0 to 34.1. However, vertically high-resolution salinity and dissolved oxygen observations since the 1990s enabled us to separate the water into at least three different water masses (central water, CW; deep water, DW; bottom water, BW). Recent studies have shown that the physical characteristics and boundaries between the three water masses are not constant over time, but have significantly varied over the last few decades in association with time-varying water formation processes, such as convection processes (deep slope convection and open-ocean deep convection) that are linked to the re-circulation of the Tsushima Warm Current, ocean-atmosphere heat and freshwater exchanges, and sea-ice formation in the northern part of the East Sea. The CW, DW, and BW were found to be transported horizontally from the Japan Basin to the Ulleung Basin, from the Ulleung Basin to the Yamato Basin, and from the Yamato Basin to the Japan Basin, respectively, rotating counterclockwise with a shallow depth on the right of its path (consistent with the bottom topographic control of fluid in a rotating Earth). This horizontal deep circulation is a part of the sea's meridional overturning circulation that has undergone changes in the path and intensity. Yet, the linkages between upper and deeper circulation and between the horizontal and meridional overturning circulation are not well understood. Through this review, the remaining issues to be addressed in the future were identified. These issues included a connection between the changing properties of CW, DW, and BW, and their horizontal and overturning circulations; the linkage of deep and abyssal circulations to the upper circulation, including upper water transport from and into the Western Pacific Ocean; and processes underlying the temporal variability in the path and intensity of CW, DW, and BW.

No-reference objective quality assessment of image using blur and blocking metric (블러링과 블록킹 수치를 이용한 영상의 무기준법 객관적 화질 평가)

  • Jeong, Tae-Uk;Kim, Young-Hie;Lee, Chul-Hee
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.46 no.3
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    • pp.96-104
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    • 2009
  • In this paper, we propose a no-reference objective Quality assessment metrics of image. The blockiness and blurring of edge areas which are sensitive to the human visual system are modeled as step functions. Blocking and blur metrics are obtained by estimating local visibility of blockiness and edge width, For the blocking metric, horizontal and vertical blocking lines are first determined by accumulating weighted differences of adjacent pixels and then the local visibility of blockiness at the intersection of blocking lines is obtained from the total difference of amplitudes of the 2-D step function which is modelled as a blocking region. The blurred input image is first re-blurred by a Gaussian blur kernel and an edge mask image is generated. In edge blocks, the local edge width is calculated from four directional projections (horizontal, vertical and two diagonal directions) using local extrema positions. In addition, the kurtosis and SSIM are used to compute the blur metric. The final no-reference objective metric is computed after those values are combined using an appropriate function. Experimental results show that the proposed objective metrics are highly correlated to the subjective data.

Horizontal 2-D Finite Element Model for Analysis of Mixing Transport of Heat Pollutant (열오염 혼합 거동 해석을 위한 수평 2차원 유한요소모형)

  • Seo, Il Won;Choi, Hwang Jeong;Song, Chang Geun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.6B
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    • pp.507-514
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    • 2011
  • A numerical model has been developed by employing a finite element method to simulate the depth-averaged 2-D dispersion of the heat pollutant, which is an important pollutant material in natural streams. Among the finite element methods, the Streamline Upwind/Petrov Galerkin (SUPG) method was applied. Also both linear and quadratic elements can be applied so that irregular river boundaries can be easily represented. To show the movement of heat pollutants, the reaction term describing heat transfer was represented as an equation in which sink/source term is proportional to the difference between the equilibrium temperature and water surface temperature. The equation was expressed so that the water surface temperature changes according to the temperature transfer coefficient and the equilibrium temperature. For the calibration of the model developed, analytic and numerical results from a case of rectangular channel with full width continuous injection have been compared in a steady state. The comparisons showed that the numerical results were in good agreement with analytical solutions. The application site was selected from the downstream of Paldang dam to Jamsil submerged weir, and overall length of this site is about 22.5 km. The change of water temperature caused by the discharge from the Guri sewage treatment plant has been simulated, and results were similar to the observed data. Overall it is concluded that the developed model can represent the water temperature changes due to heat transport accurately. But the verification using observed data will further enhance the validity of the model.

New fabrication of CIGS crystals growth by a HVT method (새로운 HVT 성장방법을 이용한 CIGS 결정성장)

  • Lee, Gang-Seok;Jeon, Hun-Soo;Lee, Ah-Reum;Jung, Se-Gyo;Bae, Seon-Min;Jo, Dong-Wan;Ok, Jin-Eun;Kim, Kyung-Hwa;Yang, Min;Yi, Sam-Nyeong;Ahn, Hyung-Soo;Bae, Jong-Seong;Ha, Hong-Ju
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.20 no.3
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    • pp.107-112
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    • 2010
  • The Cu$(In_{1-x}Ga_x)Se_2$ is the absorber material for thin film solar cell with high absorption coefficient of $1{\times}10^5cm^{-1}$. In the case of CIGS, the movable energy band gap from $CuInSe_2$ (1.00 eV) to $CuGaSe_2$ (1.68 eV) can be acquired while controlling Ga contain ratio. Generally, the co-evaporator method have used for development and fabrication of the CIGS absorption layer. However, this method should need many steps and lengthy deposition time with high temperature. For these reasons, in this paper, a new growth method of CIGS layer was attempted to hydride vapor transport (HVT) method. The CIGS mixed-source material reacted for HCl gas in the source zone was deposited on the substrate after transporting to growth zone. c-plane $Al_2O_3$ and undoped GaN were used as substrates for growth. The characteristics of grown samples were measured from SEM and EDS.