• Journal of radiological science and technology
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• v.38 no.3
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• pp.267-276
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• 2015

The gallbladder(GB) polyps have malignant potential and nowadays are increasing due to the extended use of ultrasonography. Even though there are various reports on the risk of GB polyps, there is few study on the relationship between the presence of metabolic syndrome including serum biochemistry, lifestyle and the development of gallbladder polyps in korean population. The aim of this study is to establish a relationship between the presence of metabolic syndrome including serum biochemistry and the development of gallbladder polyps in korean population. This study conducted on 151 men and 167 women who visited a musculoskeletal hospital in Gyeonggido to have an ultrasound scan of the abdomen from November 2, 2012 to January 31, 2014. They are randomly selected to evaluate the prevalence risk factors were analyzed by comparing various variables between the GB polyp positive and negative. The collected data were analyzed using the personal computer program SPSS version 20.0 for windows. The mean size of the GB polyps was 3.92mm in diameter. Size of GB polyps were less than 10mm in diameter. As to frequency in the people with the GB polyps, the number of patients with the GB polyps was 184(57.9%): the number of metabolic syndrome of them was 114(26.4%); these results showed that risk of the GB polyps got higher at patients with metabolic syndrome. As to the risk of the GB polyps, people with the GB polyps had significantly higher risk than those without the GB polyps, as follows: The risk was significantly 1.061 times higher by weight; 1.186 by BMI; 1.060 by systolic blood pressure; 1.030 by diastolic blood pressure; 1,009 by Total cholesterol; 2.736 by metabolic syndrome; 1.011 by blood sugar on an empty stomach; 1.064 by ESR. The risk factors of GB polyps were found to be weight, BMI, total cholesterol, Triglycerol, Glucose, systolic blood pressure, diastolic blood pressure, ESR and metabolic syndrome. This study has a possibility to be used an indicator to identify the GB polyps, and in the future larger-scale study will have to be conducted to objectify it.

• Journal of the Korean Society of Food Science and Nutrition
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• v.31 no.6
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• pp.1035-1042
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• 2002

This study was conducted to investigate the effect of sodium intake on serum lipids and glucose. 20 young adult women were fed the diets containing 290.5 mEq (high-Na diet) and 51.3 mEq (low-Na diets) Na for 6 days, respectively. Serum lipids, glucose, and other parameters after high-Na diet and low-Na diet were compared. The results would be summarized as follows. The mean age, body weight, height, and blood pressure of the subjects were 22.9$\pm$2.5 years,54.7+6.6 kg, 160.0$\pm$4.8 cm, 110.3$\pm$7.7/67.5$\pm$19.7 mmHg, respectively. Body weight, BMI, and diastolic blood pressure were significantly higher at the end of high-Na diet than of low-Na diet (p<0.001 p<0.001, p<0.05). However, there were not significantly different in height and systolic blood pressure between high- and low-Na diet. Serum cholesterol, LDL-cholesterol, and HDL-cholesterol were not significantly different with Na intakes. Serum triglyceride was significantly higher at the end of high-Na diet than of low- Na diet (p<0.05) Serum apo A-I was significantly decreased in low-Na diet, while apo B was increased (p<0.001, p<0.001). Thrombin time and prothrombin time, blood aggregation time were significantly faster following low-Na diet (p<0.001, p<0.05). There was not significantly different in serum glucose between high- and low-Na diet. However, serum insulin was significantly higher following low-Na diet (p<0.01). It is concluded that diastolic blood pressure, serum triglyceride, serum apo A-I, blood aggregation time were decreased in low-Na diet, while serum apo B and serum insulin were increased. These results suggest that Na-restricted diet affects not only blood Pressure but other biochemical parameters in blood. Therefore, for the patients who need restricted Na diet, it would be suggested that various biochemical changes should be carefully considered along with dietary Na manipulation.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.2
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• pp.78-82
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• 2014

Purpose The physiological and biochemical responses of healthy men and women to life stress were measured in order to investigate the correlation between these two responses under the normal situation. Materials and Methods The population of the research is some randomly chosen health college students located in Daejeon City during the period from August to September 2014, and the sample of 94 students. Heart rate variability (HRV), blood pressure (BP) were selected as physiological stress indices and serum cortisol level was used as a biochemical stress biomaker. The data which is collected used SPSS19.0 programs and frequency and percentage and T-test, correlation. Results Male showed the significant higher value of serum cortisol level (p<0.05), BP (p<0.05), and LF/HF ratio of HRV (p<0.05) than female. The difference of BP between correlated significantly with serum cortisol level (p<0.05). The LF/HF ratio of HRV also correlated significantly with serum cortisol level (p<0.05) Conclusion We suggest that LF/HF ratio of HRV and BP may be good indices for the assessment of life stress.

• Journal of Nutrition and Health
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• v.54 no.5
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• pp.459-473
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• 2021

Purpose: Although numerous systematic reviews or meta-analysis have reported the hypotensive effects of garlic, the application of these results in the area of functional food is limited. This is because the trials used various garlic preparations and patients with differing hypertensive intensities. To validate the use of garlic powder as a blood pressure lowering functional food, we performed the current meta-analysis, focusing on the study of prehypertensive subjects. Methods: Literature search was carried out using various database up to July 2020, including PubMed, Cochrane, ScienceDirect and Korean studies Information Service System, and each study was screened by pre-stated inclusion/exclusion criteria. We identified nine trials that met the eligibility, of which two studies with moderate or high risk of bias were excluded. Results: Meta-analysis of the seven studies revealed that an intake of garlic powder significantly lowered the systolic blood pressure (SBP) and diastolic blood pressure (DBP) by -6.0 mmHg (95% confidence interval [CI], -11.2, -0.8; p = 0.025) and -2.7 mmHg (95% CI, -5.3, -0.1; p = 0.046), respectively. Shapes of the funnel plot for both SBP and DBP seemed symmetrical, and the Egger's regression revealed no publication bias. Moreover, duration of the intervention period was inversely associated with the pooled effects of garlic powder on SBP (p = 0.019) and DBP (p = 0.019), and this result was supported by the subgroup-analysis. The daily dose of garlic powder, baseline value of each biomarker, and subject number, did not moderate the effects on SBP and DBP. Conclusion: Results of the present meta-analysis indicate that garlic powder supplements are superior to placebo for improving the BP in prehypertensive individuals.

• Journal of Veterinary Clinics
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• v.26 no.6
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• pp.539-546
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• 2009

The effect of hemorrhage on the electroencephalogram(EEG) was investigated in fifteen mixed-breed dogs anesthetized with ketamine, propofol and isoflurane. Animals were randomly allocated to three groups (n = 5) by anesthetic agents; group 1 (ketamine 5 mg/kg, IV), group 2 (propofol $156\;{\mu}g$/kg/min, IV) and group 3 (isoflurane 2.0% end-tidal concentration). Medetomidine ($40\;{\mu}g$/kg, IM) was used in all dogs as a preanesthetic agent. Recording electrode for EEG was positioned at CZ. EEG, heart rate, systolic/diastolic blood pressure, $pCO_2$, $pO_2$ and blood pH were measured before anesthesia, after anesthesia and after every bleedings. Three bleedings were accomplished by drawing blood through the femoral artery catheter at a rate of 7 ml/kg (10% of total blood volume) for 10 minutes. In the course of hemorrhage, a systolic/diastolic pressure continuously decreased in all groups. The $pCO_2$ values and heart rates were increased in all groups. The $pO_2$ values were most significantly increased in group 1 compared with those in other groups. The pH values were not significantly changed. On statistical analysis of EEG, there was no significant changes in group 1 and 3. But in group 2, band 3, 4 and 7 were significantly altered after 2nd and 3rd bleeding. Power alterations of band 3, 4 and 7 were thought to be related with hemorrhage over 20% of total blood volume in group 2. In conclusion, the regulation of infusion rate would be considered when a dog, anesthetized with propofol, bleed over 20% of total blood volume.

• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.3
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• pp.513-519
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• 1999

Chloral hydrate is one of the most widely used sedative agents to control the difficult to treat young age group in the dental clinic. We are often frustrated to see the patient still awake and cry with agitation even after far more than the normal onset time. In such a case, the patient has to be rescheduled for another sedation visit with different agents and/or routes which greatly disappoints the guardians. This case report presents a sedative regimen that can possibly help the clinician complete scheduled treatment without postponement. We have tried sleep induction with Enflurane (1-1.5vol%) for 60 seconds to 37 patients of those who failed to respond properly to the dose(70mg/kg)of oral Chloral hydrate. The average age and weight of the patients was 34.3 months(22-43mo.) and 14.9kg(11-21kg) respectively. It is suggested that sleep induction with low dose Eflurane produced a stable state during dental treatment with respect to vital sign and behavior. Evidence of adverse effect was not detected or reported during and/or after the procedures.

• Journal of Life Science
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• v.22 no.6
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• pp.744-750
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• 2012

The aim of the present study is to investigate the effects of 12 weeks-moderate aerobic exercise training on body composition, adiponectin, retinol-binding protein-4 (RBP-4), and vascular inflammation factors in obese children. The subjects were classified into two groups, one of which was an exercise group (n=15) practicing moderate aerobic exercise training for 12 weeks, and the other group, the control group (n=13), was not in that program. The exercise group participants performed on the treadmill running at heart rate reserve (HRR) 50% of exercise intensity for 300 kcal of the consumed time. The results of all the studies and inspections are as follows: Weight, body mass index, body fat, and systolic and diastolic blood pressure were significantly lower, while $VO_2$ max was higher in the exercise group than in the control group (p<0.05, respectively). Fasting glucose, insulin, and HOMA-IR levels in the exercise group were significantly decreased (p<0.05), whereas adiponectin levels in the exercise group were significantly increased after 12 weeks' exercise training (p<0.05). In addition, our results showed that RBP4, C-reactive protein (CRP), and interleukin-6 (IL-6) concentrations in the exercise group were significantly lower than those of the control group (p<0.05). This investigation has shown that a 12 weeks-regular aerobic exercise program offers useful effects such as an amelioration of inflammation and body indices in obese children.

• The Korean Journal of Physiology
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• v.20 no.2
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• pp.279-288
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• 1986

In an attempt to observe the to long-term training effects, the exercise of rope-skipping was regularly loaded to nine soldiers for nine weeks. And some physical characteristics, cardiopulinonary functions. some blood constituents were measured before, during and after the load of test exercise. treadmill running, and were compared with the pre-trained values. The results obtained were as follows: 1) Body weight, body surface area, skinfold thickness and total body fat decreased sifnificantly after the training. 2) The post-trained values of MVV and $FEF_{25%}$, increased significantly. 3) By the training, heart rates decreased very significantly in the resting, exercising and recovery periods. 4) After the training, the systolic blood pressures of the resting and recovery periods decreased meaningfully, while diastolic blood pressures increased significantly through the recovery stages. 5) In spite of the training, the respiration rates never change in both the resting and the recovery periods. 6) After the training, total cholesterol concentration of the venous blood decreased significantly in the resting the early recovery phases while the blood levels of glucose and HDL-cholesterol decreased very slightly. 7) Blood lactate concentration decreased through the recovery periods and the value of the recovery 20 and 60 minutes decreased obviously, in comparison with the pre-trained values. The above results suggest that the 9 week-training of the rope-skipping brings about the decrease of the body fat contents, the enhancement of cardiopulmonary functions and some changes in the blood constituents.

• The Journal of the Korea Contents Association
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• v.11 no.6
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• pp.289-301
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• 2011

This study is a research based on the non-equivalent control group pretest-posttest design whose purpose is to examine the effects of music therapy on the anxiety of patients who take the magnetic resonance imaging(MRI) test and their feeling of discomfort during the test. "The first hypothesis that the experimental group who receive music therapy will be lower in score for anxiety during the MRI test than the control group who do not was supported because after the therapy, the experimental group was found significantly decreased in that score in comparison to the control group. "The second hypothesis that the experimental group who receive music therapy will be fewer in vital signs after the MRI test than the control group who do not" was rejected in terms of both systolic and diastolic blood pressure. But the same hypothesis was partially supported because the two groups showed a significant difference in pulse rate after the test. "The third hypothesis that the experimental group who receive music therapy will be less in the feeling of subjective discomfort during the MRI test than the control group who do not" was verified to find that the two groups were significantly different from each other in the feeling. Specifically, there was a significant difference between the two groups in only one sub-area of that feeling, that is, tension. These findings suggest that music therapy could be an alternative method which can effectively reduce the state anxiety of patients during the magnetic resonace imaging(MRI) test.

• The Journal of the Korea Contents Association
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• v.17 no.2
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• pp.38-46
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• 2017

This research aimed to identify the correlation between the metabolic syndrome, which is one of the cardiovascular risk factors and emerging as an issue in the society, and the serum uric acid level. The research was conducted on a total of 1,444 patients who took a medical examination at a health examination center. The research subjects were composed of 977 men and 467 women. By conducting physical measurement and the blood test on the subjects, the research identified the correlation between the serum uric acid level and the metabolic syndrome and compared the number of the risk factors by dividing the class of the serum uric acid. The average level of serum uric acid was identified higher in men at $6.30{\pm}1.39mg/dL$ than $4.43{\pm}0.89mg/dL$ in women. Men had a correlation between age, waist size, systolic blood pressure, neutral fat, HDL-cholesterol, WBC count and ESR and the serum uric acid level (p<0.05), while women had a correlation between waist size, diastolic blood pressure level, neutral fat, HDL-cholesterol and ESR and the serum uric acid level (p<0.05). The number of the risk factors depending on the serum uric acid level increased as the serum uric acid level rose. The overall prevalence rate of the metabolic syndrome was higher in men at 17.4% than 10.2% in women. This showed that there is a statistically relevant relevance between the metabolic syndrome and the serum uric acid level, and the number of the risk factors of the metabolic syndrome will go up with an increase in the serum uric acid level.