• Clinical and Experimental Pediatrics
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• v.50 no.2
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• pp.157-162
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• 2007

Purpose : The purpose of this study was to analyze the epidemiology, causative organism, clinical manifestation and prognosis of bacterial meningitis for children after the introduction of Haemophilus influenzae type b (Hib) vaccine in Daejeon and Chungcheong area. Methods : We analyzed retrospectively 53 medical records who had been diagnosed with bacterial meningitis at 10 general or university hospitals in Daejeon and Chungcheong area. All patients aged 1 month-14 years admitted between January 2001 through December 2005. Results : During the 5-year study period, 40 of all cases were positive for bacterial growth. Of the 40 cases that were CSF culture-proven bacterial meningitis, Streptococcus peumoniae was the most common bacteria for 17 (32.1%) of all cases, followed by H. influenzae for 10 (18.9%), Neisseria meningitidis for 3 (5.7%). In this study, the most common clinical manifestation is fever, accompanied by all cases. CSF leukocyte count was more than $100/mm^3$ in 45 (84.1%) cases. CSF glucose concentration was less than 50 mg/dL in 42 (79.2%) cases and protein concentration was more than 45 mg/dL in 49 (92.5%) cases. 45 of all cases made a recovery after treatment and were discharged. Most common complication after treatment is subdural effusion (19.0%) and hearing disturbance (9.4%). Conclusion : The most common organism of culture-proven bacterial meningitis in the children beyond neonatal period was S. pneumoniae. Continued surveillance studies were demanded to know the altered incidence of bacterial meningitis, because we expect the incidence of S. pneumoniae meninigitis will be on the decrease after more active innoculation of pneumococcal protein conjugate vaccine.

• Pediatric Infection and Vaccine
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• v.12 no.2
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• pp.202-207
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• 2005

Intravenous immune globulin(IVIG) is widely used for immune thrombocytopenic purpura (ITP), Kawasaki disease and other autoimmune neuromuscular disease. Aseptic meningitis was one of the most serious neurologic complications reported following the use of IVIG. We experienced 4 episodes of aseptic meningitis associated with IVIG usage in 3 patients from 2003 to 2004. Underlying disease of each patients was ITP, Kawasaki disease and myathenia gravis and all of them received high dose IVIG treatment for their underlying disease. Within a days, they started to complain severe headache and diagnosed meningitis by cerebrospinal fluid analysis. Cerebrospinal fluid leukocyte counts varied from 92 to over a thound per microliter with dominance of polymorphonuclear leukocytes. Microbiologic studies revealed no organisms. All of them were free from headache within 2 days and did not suffer any neurological sequelae.

• Journal of Veterinary Clinics
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• v.23 no.3
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• pp.344-348
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• 2006

A 5-year-old, male Yorkshire terrier dog was presented with progressive seizure and anorexia. Definitive diagnosis of necrotizing meningoencephalitis(NME) was made based on characteristic clinical features, brain lesion with MRI, and histopathologic examination. The dog was treated with prednisolone for 20 days, firstly. Prednisolone and mycophenolate mofetil(MMF) were then administered for 40 days following the initial therapy. However, the clinical signs were not improved and seizure frequency was increased. This patient survived around 2 months after diagnosis. This case report described the clinical findings, imaging characteristics and pathologic features of NME in a Yorkshire terrier with trial treatment using MMF.

• Journal of Veterinary Clinics
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• v.28 no.3
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• pp.323-327
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• 2011

A Jindo dog (8-month-old, intact male) was referred for hind limb lameness on the right side. The dog was diagnosed with a simple femoral fracture by radiological examination. After surgical fixation of the femoral fracture, tramadol: a narcotic-like synthetic analgesic was intravenously administrated for post-operative analgesia. After injection of the tramadol, generalized tonic clonic seizure was immediately occurred in the dog. Seventeen hours later, the dog died despite intensive care. We suspected that tramadol might induce the seizurogenic effect resulted in death. A necropsy was performed to examine the cause of the death. In consequence, the dog was diagnosed as necrotizing meningoencephalitis (NME) based on histopathological examination. We would be concerned that tramadol may be related to seizure activity in the NME patient. From this case, it is known that although tramadol has been proven to be a safe and effective agent for the control of pain in veterinary medicine, it would be carefully used to patient with history of neurological diseases including meningoencephalitis, hydrocephalus, and encephalopathy.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.283-283
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• 2020

국가의 논의 타작물 재배 권장 정책과 농한기 수익을 위해서 동절기에도 농사가 가능한 시설농업이 발달했으며, 1990년 초부터 재배면적이 증가하여 2000년에는 10만 ha를 넘어섰고, 2018년에는 80만ha의 규모를 보이고 있다(농사로, 2019). 시설농업단지의 동절기 난방을 위한 에너지원으로 화석연료와 전기열원을 사용하고 있고, 특히 강변의 경우 지하수를 난방 열원으로 사용가능해 수막재배를 이용한 대규모 시설단지가 발달함에 따라 지하수의 이용량이 증가하고, 2015년 농업용 지하수 이용량은 연간 20억 톤에 이른다(GIMS, 2019). 난방이 필요한 동절기에 수막용수를 위한 지하수 이용량이 급증하여 계절적인 수위변화를 보이며, 특히 강변의 대규모 시설농업단지의 지하수의 부족현상이 빈번히 발생하는 실정이다(송성호, 2017). 본 연구지역은 낙동강 하구댐 설치 전만조 시 해수의 유입으로 암반지하수의 심도가 증가할수록 EC가 증가하는 특성을 보이는 곳으로, 지하수의 이용량이 급증하는 동절기에 특히 급격히 증가하여 지하수의 안정적인 수질관리를 위해 염분변화의 관리가 필요한 지역이다. 지하수의 계절적인 변화를 위해 시설농업단지내에 지하수 관측정이 설치되어 관측되고 있으며 본 연구에서는 관측정의 2013년 1월~2019년 1월까지 지하수의 EC변화를 관측하였다. 지하수의 수위(GL.m), 온도, EC를 1시간 주기로 관측하여 계적적인 변화를 분석하였고, EC의 증가가 큰 곳은 심도별로 센서(다중심도)를 설치하여 염도의 변화를 관측하였다. 지하수성분의 지질학적 기원분석을 위한 양음이온 분석을 연 1회 실시하였다. 또한 관측정의 심도별 변화를 알기 위해 동일지역에 충적, 암반 관측정을 따로 설치하고 관측하여 지표수와 지하수의 심도별 영향의 차이를 분석하였다. 동일지역의 관측결과 평균 5m이하의 수위변화를 보이나, 5m 이상의 수위변동을 보이는 관측망은 15년 14개소 17년 19개소로 증가추세를 보이며, 이는 주로 밀집된 시설하우스 단지의 수막재배를 위한 겨울철 지하수 사용량 증가가 원인인 것으로 판단된다. 본 연구지역은 강변지역에 밀집된 시설하우스단지의 동절기 수막재배를 위한 지하수 과다 사용으로 수위급감 및 수량부족현상이 반복되고 있어, 예방과 대책강구를 위해 지표수의 함양과 지하수사용량의 상관관계 분석과 자료축적 및 추가연구를 위한 장기관측이 요구된다.

• Annals of Clinical Neurophysiology
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• v.11 no.2
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• pp.81-82
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• 2009

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2002.11a
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• pp.382-393
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• 2002

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2006.11a
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• pp.244-245
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• 2006

• Proceedings of the Korean Nuclear Society Conference
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• 2004.05a
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• pp.150.1-150.1
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• 2004

• Proceedings of the Korea Institute of Fire Science and Engineering Conference
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• 2001.11a
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• pp.245-251
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• 2001