• Journal of the Korean Recycled Construction Resources Institute
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• v.9 no.4
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• pp.419-424
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• 2021

This study investigated the possibility of early determination of frost damage on the concrete surface by using the rebound hardness method, widely used for estimation the compressive strength of concrete on the site. For this purpose, the surface damage of concrete was compared by measuring the rebound hardness and the relative dynamic modulus of the concrete for the multi-sided and single sided concrete surface exposed to freeze and thaw condition. Compared to the resonance vibration method, the rebound hardness method was able to show the frost damage 150 cycles quicker for the single-sided exposed concrete specimen and 50 cycles quicker for the multi-sided exposed concrete specimen. Therefore, it is considered that the rebound hardness method can determine the concrete surface damage more quickly than that of the resonance vibration method.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.15 no.2
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• pp.55-62
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• 2020

연구 목적 이 연구는 내측 반월상 연골판 손상으로 인한 무릎 통증을 호소하는 5명의 환자에서 한의학적 치료, 특히 신바로 약침으로 인한 통증 개선이 있었기에 보고함이다. 연구 방법 무릎 통증으로 본원 입원치료를 받은 환자 중, MRI 영상 검사상 내측 반월상 연골 파열 진단을 받은 환자들의 차트를 분석하였다. 슬관절 통증 호전 및 기능 개선은 Numeric Rating Scale (NRS), Western Ontario and McMaster Universities Arthritis Index (WOMAC Index), 슬관절 Range Of Motion(ROM) 및 special tests 측정으로 판단하였다. 연구 결과 5증례에서 NRS는 평균 3.4의 호전, WOMAC Index는 평균 64.4%의 호전을 보였다. 슬관절 ROM 측정에서 환자 모두 입원시보다 증가되었으나, 무릎에 손상에 사용되는 보편적 검사인 Stress valgus, Stress varus, Drawer test, Apley compression test, Mcmurray's test 상 전후비교에서 4명의 환자는 호전되었고, 1명 환자에서는 변화가 없었다. 결과 이 연구는 내측 반월상 연골판 손상에 대한 신바로 약침을 포함한 한의학적 치료 후 단기간 내 통증 및 기능 향상을 보여주었다.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1289-1297
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• 2023

In this study, NF Complex of 0%, 0.5%, 2.5%, 12.5%, and 100% was prepared by complexing and extracting Indian gooseberry, Rosa multiflora Thunberg roots, and saw palmetto fruit in a ratio of 5:1:1. The manufactured NF Complex was applied to bleached sample hair and then compared and analyzed with damaged hair. To confirm the improvement effect, tensile strength, gloss, absorbance, and brightness were measured. As a result of the measurement, the tensile strength increased. The gloss content decreased by 100%, but the remaining content increased. The change in absorbance was minimal. There was also a change in brightness, but it was minimal. It was confirmed that there is a significant difference in the average value of NF Complex, and it is judged necessary to study various ratios in the future.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.3
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• pp.229-237
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• 2007

In this study, an artificial neural network (ANN)-based damage detection algorithm using acceleration signals is developed for real-time alarming locations of damage in beam-type structures. A new ANN-algorithm using output-only acceleration responses is designed tot damage detection in real time. The cross-covariance of two acceleration-signals measured at two different locations is selected as the feature representing the structural condition. Neural networks are trained lot potential loading Patterns and damage scenarios of the target structure for which its actual loadings are unknown. The feasibility and practicality of the proposed method are evaluated from laboratory-model tests on free-free beams for which accelerations were measured before and after several damage cases.

• Applied Biological Chemistry
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• v.48 no.2
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• pp.155-160
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• 2005

Electrolyzed reduced water (ERW), showing extremely negative oxidation-reduction potential, was used to investigate the effects of paraquat-induced damages on DNA from human lymphocyte. The effect of ERW on paraquat-induced oxidative DNA damage in human lymphocytes was evaluated by Comet assay (single-cell gel electrophoresis) quantified as percentage fluorescence in tail. Comet assay has been used widely to assess the level of the DNA damage in individual cells. Lymphocytes were oxidatively challenged with various concentrations of paraquat for 30 min at $37^{\circ}C$, and were then treated with electrolyzed reduced water for 30 min. The oxidative DNA damage by paraquat, as indicated by the fluorescent tail in DNA, increased in a dose-dependent manner. However, oxidative damage of the DNA was almost completely prevented upon treatment with electrolyzed reduced water.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.12
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• pp.4922-4927
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• 2010

In order to investigate whether the ethanol extract of Acanthopanax sp. might inhibit herbicide-induced DNA damage and erythrocyte damage, the suppression of the oxidative DNA damage of lymphocyte and erythrocyte damage in the presence of the extract were evaluated by comet assay and hemolysis assay, respectively. Phenoxy herbicides, named 2,4-D (2,4-dichlorophenoxyacetic acid) and 2,4,5-T (2,4,5-trichlorophenoxyacetic acid) and bipyridyl herbicide paraquat induced oxidative DNA damages of lymphocytes. However, the oxidative DNA damage by 2,4-D, 2,4,5-T or paraquat was inhibited in vitro upon treating Acanthopanax extract. Moreover, the erythrocyte damage was also suppressed in vitro by Acanthopanax extract treatment.

• Journal of Korean Society of Steel Construction
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• v.17 no.2 s.75
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• pp.173-181
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• 2005

This study deals with a method to identify damages of free vibrating thin plate structures using the combined finite element method (FEM) and the advanced uniform micro-genetic algorithm.To solve the inverse problem using the combined method, this study uses several natural frequencies instead of mode shapes in a structure as the measured data. The technique described in this paper allows us not only to detect the damaged elements but also to find their numbers, locations, and the extent of damage.To demonstrate the feasibility of the proposed method, the algorithm is applied to a free vibrating steel thin plate structures with arbitrary damages. From the standpoint of computation efficiency, the proposed method in this study has advantages when compared with the existing simple genetic algorithms. The numerical examples demonstrate that the method using micro-genetic algorithms can possibly detect correctly the damages of thin plates from only several natural frequencies instead of their natural modes.

• Journal of Life Science
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• v.19 no.10
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• pp.1489-1494
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• 2009

This study was designed to investigate the effects of swimming and minocycline on motor function recovery and Bcl-2 expression after spinal cord injury (SCI) in rats. After operation, neurological motor behavior test (BBB scale) on days 1, 4, 7, 10, and 14 were tested. Western blot and immunohistochemical assessment (Bcl-2) were performed on day 14. BBB scale started to show a statistically significant difference on day 7 (p<0.05). On day 14, it showed the most significant (p<0.05) difference. Expression of Bcl-2 increased in all the experimental groups. In particular, the highest expression of Bcl-2 appeared in the swimming and minocycline groups. Based on these results, minocycline and swimming were the most effective factors in the motor behavior function and immunohistochemical assessment of SCI rats.

• The Journal of Korean Medicine
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• v.22 no.3
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• pp.21-30
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• 2001

목적 : 이전 연구에서 단삼 추출액이 강력한 항산화 작용이 있음을 확인한 바 있어 단삼 추출액이 신장세뇨관 세포에서 oxidant에 의한 세포사망 및 DNA 손상을 방지하는 지를 조사하고 이러한 효과가 지질의 과산화를 억제하는 효과에 기인하는 지를 시험하였다. 방법 : 신장 근위세뇨관 세포 유래 세포주인 opossum kidney (OK)세포를 이용하여 세포 사망은 frypan blue exclusion방법을 이용하여 평가하였고, DNA손상 정도는 double stranded DNA의 파괴를 측정하여 평가하였다. Oxidant 약물 모델로는 $H_2O_2$를 사용하였다. 결과 : $H_2O_2$는 적용시 간과 농도에 비례하여 세포 사망을 유도하였다. 단삼 추출액은 0.05% 농도에서 $H_2O_2$에 의한 세포사망 및 DNA 손상을 방지하였다. 이러한 방지효과는 $H_2O_2$ 제거 효소인 catalase와 철 착염제인 deferoxamine에 의해서도 나타났다. 그러나 강력한 항산화제인 DPPD는 $H_2O_2$에 의한 세포 사망이나 DNA손상을 방지하지 못하였다. $H_2O_2$는 세포내 ATP 농도를 감소시켰으며. 이러한 감소는 poly (ADP-ribose) polymerase억제제인 3-aminobenzamide에 의해 방지되었으나 단삼 추출액에 의해서는 영향을 받지 않았다. 3-aminobenzamide는 $H_2O_2$에 의한 세포 사망을 방지하였다. $H_2O_2$는 지질의 과산화를 증가시켰으며, 이러한 변화는 단삼 추출액과 DPPD에 의해 방지되었다 결론 : OK 세포에서 $H_2O_2$에 의한 세포사망과 DNA 손상에는 지질의 과산화가 중요한 역할을 하지 않으며, 단삼 추출액의 $H_2O_2$에 의한 세포 사망과 DNA 손상 방지 효과는 항산화 작용이 아닌 다른 기전에 기인하는 것으로 사료된다.

• Journal of Conservation Science
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• v.29 no.2
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• pp.93-102
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• 2013

The wooden Ksitigarbha Triad Statues (Treasure No. 1749) of Shinhungsa temple in Sokcho are enshrined in the inside of the Myeonbujeon Hall. The Statues are highly damaged physical weathering which are crack and exfoliation. Also, the Statues were deteriorated by chemical and biological weathering. This study carried out nondestructive method as deterioration map, ultrasonic measurement, X-ray and endoscopy survey for deterioration evaluation and conservation plan. As a result, Ksitigarbha Statue coated by dust and various pollutants. And gold-gilt of Statue's surface has peeled off. Head part of Mudokguiwang Statue was discolored from water leak in Myeongbujeon Hall. Domyeongjonja Statue is highly damaged by insects. Result of endoscopy, there were bee hives in the inside of the Statue. Therefore, we suggest that these Statues have need to do conservation treatment on the basis of diagnostic results.