• Title/Summary/Keyword: 손상 안정성

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The Otimization of Laser System for Photodynamic Therapy of Malignancies (악성종양의 광역학적 치료를 위한 레이저 시스템의 최적화)

  • 임현수;김주옥;황인경
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.41 no.6
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    • pp.51-60
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    • 2004
  • In this paper, we optimized the PDT laser system to improve the therapy effects of malignancies. In order to optimize, the variation of laser output and specific wavelength shift have to reduced. To improve the PDT therapy clinician require the diverse radiation mode which irradiate the tumor surface. Continuous wave mode that general application may causes tissue thermal damage not only to tumor tissue, but also to normal tissue. In this paper, therefore, we suggested new technique for radiation method to improved PDT effects and prevented to the thermal effects for the tissue. In the experimental we verified the stability of wavelength, laser output stability and proved the reduced thermal effects to the tissue using the pulse & burst radiation modes in vitro.

24th ITTC Benchmark Study on Numerical Prediction of Damage Ship Stability (24th ITTC 손상선박 안정성 수치해석 연구)

  • Cho, Seok-Kyu;Hong, Sa-Young;Lee, Kyung-Jung;Kyoung, Jo-Hyun;Kim, Young-Sik
    • Journal of the Society of Naval Architects of Korea
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    • v.42 no.5 s.143
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    • pp.435-447
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    • 2005
  • The 24th ITTC Specialists Committee on Stability in Waves is conducting an international benchmark study where numerical methods for the calculation of ship motion in damaged condition are compared on the basis of specified tests in order to assess the present state of the art in this field. The study is finished and some results are presented in this paper providing an initial insight into the status of damage models and numerical methods and a collective assessment of their performance. The preliminary analysis has shown that current methods are satisfactory, capturing the fundamental physical performance of damaged ships in specified conditions.

가스배관 결함평가 현황

  • O, Gyu-Hwan;Yeom, Gyu-Jeong;Kim, U-Sik
    • Journal of the KSME
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    • v.54 no.1
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    • pp.38-42
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    • 2014
  • 운영 중인 가스배관에는 매우 낮은 빈도이긴 하지만 부식, 기계적 손상, 내압, 토양하중, 차량하중, 지반침하, 열하중, 균열 등이 생길 수 있다. 안정적인 가스공급과 안전한 배관 운영을 위해서는 손상배관에 대한 건전성 평가가 필요하다. 평가 방법은 국내외 규격을 적용하거나 배관 운영회사에서 독자적인 건전성 평가방안을 적용하면 된다. 결함평가 방안은 고압 가스배관뿐만 아니라, 중저압 가스배관, 압력용기, 원자력 배관, 화학플랜트 배관 등에 필요한 사항이다.

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Oxidative Stress in Spermatozoa during Boar Semen Storage (돼지 정액을 저장하는 동안 정자에 미치는 산화스트레스)

  • Seunghyung Lee
    • Journal of Life Science
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    • v.33 no.7
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    • pp.586-592
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    • 2023
  • Oxidative stress is a critical factor affecting the quality and viability of sperm during boar semen storage. Oxidative stress is also a significant concern during the process of freezing semen. The process of semen storage involves exposing the sperm to various stressors, including temperature changes, cryoprotectants, and extended periods of incubation. In addition, oxidative stress can lead to the production of reactive oxygen species (ROS) within the sperm, resulting in oxidative damage to cellular components, such as lipids, proteins, and DNA. Striking a balance between ROS production and the antioxidant defense system is crucial for maintaining sperm viability and functionality during semen storage. Moreover, the prolonged storage of boar semen leads to an increase in ROS levels, which can impair sperm motility, membrane integrity, and DNA integrity. ROS-induced lipid peroxidation affects the fluidity and stability of sperm membranes, leading to decreased sperm motility. Moreover, oxidative damage to the DNA can result in DNA fragmentation, compromising the genetic integrity of the sperm. In conclusion, oxidative stress is a significant challenge in maintaining sperm quality during boar semen storage. Understanding the mechanisms underlying oxidative stress and their impacts on sperm function is crucial for developing effective strategies to minimize oxidative damage and improve sperm storage outcomes.

The Inflence of Excavation Damaged Zone around an Underground Research Tunnel in KAERI (한국원자력연구원 내 지하처분연구시설 주변의 암반 손상대 영향 평가)

  • Kwon, S.;Kim, J.S.;Cho, W.J.
    • Explosives and Blasting
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    • v.26 no.2
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    • pp.11-19
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    • 2008
  • The development of an excavation damaged zone, EDZ, due to the blasting impact and stress redistribution after excavation, can influence on the long tenn stability, economy, and safety of the underground excavation. In this study, the size and characteristics of an EDZ around an underground research tunnel, which was excavated by controlled blasting, in KAERI were investigated. The results were implemented into the modelling for evaluating the influence of an EDZ on hydro-mechanical behavior of the tunnel. From in situ tests at KURT, it was possible to determine that the size of EDZ was about l.5rn. Goodman jack tests and laboratory tests showed that the rock properties in the EDZ were changed about 50% compared to the rock properties before blasting. The size and property change in the EDZ were implemented to a hydro-mechanical coupling analysis. In the modeling, rock strengths and elastic modulus were assumed to be decreased 50% and. the hydraulic conductivity was increased 1 order. From the analysis, it was possible to see that the displacement was increased while the stress was decreased because of an EDZ. When an EDZ was considered in the model, the tunnel inflow was increased about 20% compared to the case without an EDZ.

Multiple-Silo Performance Assessment Model for the Wolsong LILW Disposal Facility in Korea - PHASE I: Model Development (월성 중저준위 처분시설 다중사일로 안정성 평가 모델 - 1단계: 모델개발)

  • Lim, Doo-Hyun;Kim, Jee-Yeon;Park, Joo-Wan
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.9 no.2
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    • pp.99-105
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    • 2011
  • An integrated model for groundwater flow and radionuclide transport analyses is being developed incorporating six underground silos, an excavated damaged zone (EDZ), and fractured host rock. The model considers each silo as an engineered barrier system (EBS) consisting of a waste zone comprising waste packages and disposal container, a buffer zone, and a concrete lining zone. The EDZ is the disturbed zone adjacent to silos and construction & operation tunnels. The heterogeneity of the fractured rock is represented by a heterogeneous flow field, evaluated from discrete fractures in the fractured host rock. Radionuclide migration through the EBS in silos and the fractured host rock is simulated on the established heterogeneous flow field. The current model enables the optimization of silo design and the quantification of the safety margin in terms of radionuclide release.

A Study on Acoustic Emission and Micro Deformation Characteristics During Biaxial Compression Experiments of Underground Opening Damage (이축압축실험을 통한 지하공동 손상시 음향방출 및 미소변형 특성 연구)

  • Min-Jun Kim;Junhyung Choi;Taeyoo Na;Chan Park;Byung-Gon Chae;Eui-Seob Park
    • Tunnel and Underground Space
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    • v.34 no.2
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    • pp.169-184
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    • 2024
  • This study investigates acoustic emission (AE) and micro-deformation characteristics of circular openings through biaxial compression experiments. The experimental results showed a significant increase in the frequency, count, energy, and amplitude of AE signals immediately before damage occurred in the circular opening. The differences in frequency and count between before and after damage initiation were significantly pronounced, indicating suitable factors for identifying damage occurrence in circular openings. The results for digital image correlation (DIC) technique revealed that micro-deformation was concentrated around the openings, as evidenced by the spatial distribution of strain. In addition, spalling was observed at the end of the experiments. The AE and micro-deformation characteristics presented in this study are expected to serve as fundamental data for evaluating the stability of underground openings and boreholes for deep subsurface projects.

Determining Parameters of Dynamic Fracture Process Analysis(DFPA) Code to Simulate Radial Tensile Cracks in Limestone Blast (석회암 내 방사상 발파균열을 예측하기 위한 동적파괴과정 해석법의 입력물성 결정법에 관한 연구)

  • Kim, Hyon-Soo;Kang, Hyeong-Min;Jung, Sang-Sun;Kim, Seung-Kon;Cho, Sang-Ho
    • Explosives and Blasting
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    • v.31 no.2
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    • pp.6-13
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    • 2013
  • Recently, complaints or environmental problems caused by the noise and dust generated from crusher of the mine and quarry are emerging. Therefore mining facilities such as crushers and mills have been installed in an underground. In order to facilitate crusher equipments in the underground, excavation of large space is required and then the stability of the large space underground structure is an important issue. In this study, the blast experiments, which use a block of the limestone, are performed. Based on the blast experiments, the numerical model was prepared and simulated using dynamic fracture process analysis code(DFPA) with considering the rising time of applied borehole pressure and microscopic tensile strength variation. Comparing the non-dimensional crack length and no-dimensional tensile strength obtained from blast experiments and numerical analyses, the input parameters of DFPA code for predicting a radial tensile crack in limestone blasting were determined.

Development of hydro-mechanical-damage coupled model for low to intermediate radioactive waste disposal concrete silos (방사성폐기물 처분 사일로의 손상연동 수리-역학 복합거동 해석모델 개발)

  • Ji-Won Kim;Chang-Ho Hong;Jin-Seop Kim;Sinhang Kang
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.26 no.3
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    • pp.191-208
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    • 2024
  • In this study, a hydro-mechanical-damage coupled analysis model was developed to evaluate the structural safety of radioactive waste disposal structures. The Mazars damage model, widely used to model the fracture behavior of brittle materials such as rocks or concrete, was coupled with conventional hydro-mechanical analysis and the developed model was verified via theoretical solutions from literature. To derive the numerical input values for damage-coupled analysis, uniaxial compressive strength and Brazilian tensile strength tests were performed on concrete samples made using the mix ratio of the disposal concrete silo cured under dry and saturated conditions. The input factors derived from the laboratory-scale experiments were applied to a two-dimensional finite element model of the concrete silos at the Wolseong Nuclear Environmental Management Center in Gyeongju and numerical analysis was conducted to analyze the effects of damage consideration, analysis technique, and waste loading conditions. The hydro-mechanical-damage coupled model developed in this study will be applied to the long-term behavior and stability analysis of deep geological repositories for high-level radioactive waste disposal.

A Study on Dynamic Analysis Model and Stability of Stone Cultural Properties of Inverted Pendulum Type with 5 Joints (5개의 연결부를 가지는 역진자형 석조문화재의 동적 해석모델 및 안정성 연구)

  • Choi, Jae-Sung
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.3
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    • pp.21-30
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    • 2021
  • Architectural cultural properties suffer a lot of damage due to various environmental factors. In order to preserve damaged cultural properties, preventive preservation and long-term preservation management are becoming more important. Therefore, research on a scientific non-destructive testing method applicable to regular inspection is required. For related research, DangGan with a high flag-pole shape was selected as the subject of study among various cultural properties. Among the preserved DangGans, a basic study was conducted on the analysis technique to evaluate the structural stability by selecting Treasure No. 49 Naju SeokDangGan. An idealized model was presented and a multi-degree of freedom equation of motion was derived. In addition, an equation for estimating the critical stiffness value for each joint position is presented.