• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.4
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• pp.525-531
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• 2012

This study aims at the structural analysis of vibration and fatigue according to the configuration of engine mount. Maximum equivalent stress or deformation is shown at bracket or case respectively. As harmonic vibration analysis, the maximum displacement amplitude is happened at 4,000Hz. Among the cases of nonuniform fatigue loads, 'SAE bracket history' with the severest change of load becomes most unstable but 'Sample history' or 'Saw tooth' becomes most stable. In case of 'Sample history' or 'Saw tooth' with the average stress of 4,200MPa or 0MPa and the amplitude stress of -3,000MPa or 7MPa, the possibility of maximum damage becomes 70%. This stress state can be shown with 7 times more than the damage possibility of 'SAE bracket history' or 'SAE transmission'. The structural result of this study can be effectively utilized with the design on engine mount by investigating prevention and durability against its damage.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.6
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• pp.154-162
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• 2005

This study investigates the fatigue life and the damage possibility of connecting rod by the fatigue tool of Ansys workbench. The case of constant fatigue loading variation 'Sine' becomes more stable than that of nonconstant loading but the magnitude of constant load becomes larger than that of nonconstant load. Among nonconstant fatigue loads, the case of 'SAE Bracket History' which is severest at the variation of load tends to be most unstable. The case of 'Sample History2' which becomes a little slow at the variation of load tends to be most stable. The maximum relative damage in case of 'SAE Bracket History' is occurred near the average stress '0' and this case can be shown to have the possibility to take more damage than another case.

• Journal of the Korea institute for structural maintenance and inspection
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• v.27 no.4
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• pp.62-69
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• 2023

This study investigated the electromechanical properties of cement based smart repair materials (SRMs) according to the different amounts of fine steel slag aggregates (FSSAs). SRMs can self-diagnose the quality of repairing and self-sense the damage of repaired zone. The replacement ratios of FSSAs to sand for SRMs were 0% (FSSA00), 25% (FSSA25), and 50% (FSSA50) by sand weight. The electrical resistivity of SRMs generally decreased as the compressive stress of SRMs increased: the electrical resistivity of FSSA25 at the age of 7 hours decreased from 78.16 to 63.68 kΩ-cm as the compressive stress increased from 0 to 22.37 MPa. As the replacement ratio of FSSAs by weight of sand increased from 0% to 25%, the stress sensitivity coefficient (SSC) of SRM at the age of 7 h increased from 0.471 to 0.828 %/MPa owing to the increased number of partially conductive paths in the SRMs. However, as the replacement ratio of FSSAs further increased up to 50%, the SSC decreased from 0.828 to 0.649 %/MPa because some of the partially conductive paths changed to continued conductive ones. SRMs are expected to self-sense the quality and future damage of repaired zone only by measuring the electrical resistivity of the repaired zone in addition to fast recovery in the mechanical resistance of structures.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.164-166
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• 2003

Despite recent advances in the treatment of acute myocardial infarction, the ability to repair extensive myocardial damage is limited. Revascularization in ischemic myocardium is required to improve cardiac function and prevent further scar tissue formation. Bone marrow contains endothelial precursors that can be used to induce neovascularization in ischemic myocardium. To develop a new therapy for myocardial infarction, we investigated if implantation of bone marrow mononuclear cells (BM-MNCs) using biodegradable matrices could enhance neovascularization in ischemic myocardium. Eight weeks after implantation, the damaged myocardium implanted with BM-MNCs and fibrin gels exhibited significantly greater angiogenic responses than those implanted with either fibrin gels or BM-MNCs alone. Fibrin gels disappeared completely 8 weeks after implantation. Echocardiography revealed improved heart functions. These results suggest that implantation of BM-MNCs using fibrin gel matrix efficiently induces neovascularization and improved heart functions in ischemic myocardium.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.12
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• pp.1875-1882
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• 2013

Micro-array technology contributes numerous achievements such as ordering of gene network and integration of genomic. This technology is well established as means for investigating patterns of gene expression. DNA micro-arrays utilize Affymetric chips where a large quantity of DNA sequences may be synthesized. There are two general type of conventional DNA array spotter: contact and piezoelectric. The contact technology used spotting pin technology to make contact with the glass slide surface. This may caused damage or scratches to the surface matrix where protein will be contaminated and may not bind specifically. Piezoelectric technology available at this present time on the other hand requires the analyzer to print the result that can only be done within the laboratory despite of mass production. Therefore, in this paper, high-throughput technology is developed for providing greater consistency in feature spot without touching the glass slide surface.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.21-21
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• 2023

현재 구축되어있는 방재시설의 능력은 기후위기로 인해 수용가능한 극한강우량의 범위를 넘어서고 있어 대형화된 홍수로 인한 피해가 꾸준히 발생하고 있다. 이로 인해 잠재적 홍수로 인한 도시회복도 관리와 홍수로 수반되는 피해에 대한 복구의 중요도가 높아지고 있다. 회복도는 도시의 재해 취약성, 저항, 적응, 복구, 완화에 대한 능력을 포괄하는 개념으로써 최근 주목받고 있는 개념이지만 대부분의 연구는 주로 시설에 대한 회복도 평가가 이루어지고 있다 (Sen et al.,2021). 또한 재해 후 도시복구에 관한 연구는 다수 존재하지만 복구에 따른 지역의 회복도 변화와 라이프라인과 같은 주요 시설의 복구에 따른 회복도 차이를 고려한 연구는 미비한 실정이다. 따라서 본 연구에서는 도시침수 발생 후 라이프라인을 고려한 도시복구 우선순위 산정모델을 개발하고 재해관리의 효율성 향상측면에서 도시의 기능적 회복도를 평가하였다. 이를 위해 라이프라인 중 도로 복구결과의 평가를 위하여 리스크 매트릭스 기법을 이용한 도로위험도평가를 수행하였으며 도시의 회복도를 측정하였다. 회복도를 크게 홍수로부터 도시가 받은 영향과 재해복구역량으로 구성하였으며 정량적인 평가를 위해 각각 손상함수와 재해재난목적예비비를 활용하여 산정하였다. 이후 복구우선순위를 산정하였으며 복구와 도시회복도와의 관계를 분석하기 위하여 재해연보 자료를 기초로 회귀분석을 통해 복구비용을 추정하였다 (유순영 등.,2014). 시범지역에 적용한 결과 시설 및 도로 복구에 따른 도시영향의 변화보다 복구비사용으로 인한 재해복구역량의 변화가 더욱 크다는 것을 확인하였다. 이는 재해재난목적예비비의 중요성이 크다는 것을 의미하며 향후 추가적인 인문학적, 법제적 요소가 회복도에 미치는 영향을 연구한다면 도시회복도 향상 및 도시복구에 관한 정책적 의사결정에 큰 도움이 될 것이다.

• The Korean Journal of Nuclear Medicine
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• v.33 no.5
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• pp.439-451
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• 1999

Purpose : It is important to differentiate malignant from benign lesions of intraocular masses in choosing therapeutic plan. Biopsy of intraocular tumor is not recommended due to the risk of visual damage. We evaluated the usefulness of F-18-FDG PET imaging in diagnosing intraocular neoplasms. Materials and Methods: F-18-FDG PET scan was performed in 13 patients (15 lesions) suspected to have malignant intraocular tumors. There were 3 benign lesions (retinal detachment, choroidal effusion and hemorrhage) and 10 patients with 12 malignant lesions (3 melanomas, 7 retinoblastomas and 2 metastatic cancers). Regional eye images ($256{\times}256$ and $128{\times}128$ matrices) were obtained with or without attenuation correction. Whole body scan was also performed in eight patients (3 benign and 6 malignant lesions). Results: All malignant lesions were visualized while all benign lesions were not visualized. The mean peak standardized uptake value (SUV) of malignant lesions was $2.64{\pm}0.57g/ml$. There was no correlations between peak SUV and tumor volume. Two large malignant lesions ($> 1000 mm^3$) showed hot uptake on whole body scan. But two medium-sized lesions ($100-1000mm^3$) looked faint and two small ($<100mm^3$) lesions were not visualized. The images reconstructed with $256{\times}256$ matrix showed lesions more clearly than those with $128{\times}128$ matrix Conclusion: F-18-FDG PET scan is highly sensitivity in detecting malignant intraocular tumor For the evaluation of small-sized intraocular lesions, whole body scan is not appropriate because of low sensitivity. A regional scan with sufficient acquisition time is recommended for that purpose. Image reconstruction in matrix size of $256{\times}256$ produced clearer images than the ones in $128{\times}128$, but it does not affect the diagnostic sensitivity.

• Journal of Life Science
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• v.29 no.12
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• pp.1321-1328
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• 2019

Intermediate-wavelength solar radiation, also known as ultraviolet B (UVB: 290-320 nm) radiation, may cause premature aging and oxidative damage-dependent skin cancer in humans. UVB-induced formation of reactive oxygen species (ROS)-often a consequence of excessive exposure to these rays-could activate matrix metalloproteinases (MMPs) such as MMP-1 and MMP-3. These enzymes break down type I collagen in human fibroblasts. In this study, we assessed the antioxidant and anti-aging effects of ethyl acetate extract of blueberry (EEB). An antioxidant test in blueberries evaluated ROS production using CCD-986sk cells and DPPH assay. In order to evaluate the anti-wrinkle efficacy of blueberries, the MMP-1 production and type 1 procollagen synthesis evaluated and the expression of MMP 1, 3 were tested through Western blot and RT- PCR. EEB exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity and reduced the production of UVB-induced ROS. Also, EEB inhibited UVB-induced processes associated with photoaging and skin cancer, such as reduction in procollagen production and increase in MMP-1 production. More precisely, EEB (50 ㎍/ml) markedly suppressed mRNA and protein levels of MMP-1 and -3. The anti-aging effects are attributable to the antioxidant activity of EEB. These findings indicate that EEB has a protective effect against UVB-induced aging in human fibroblast cells by regulating the levels of type-1 procollagen, MMP-1, and MMP-3.

• Journal of the Korea Concrete Institute
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• v.22 no.2
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• pp.219-228
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• 2010

It has been well known that concrete structures exposed to acid and sulfate environments such as sewer, sewage and wastewater, soil, groundwater, and seawater etc. show significant decrease in their durability due to chemical attack. Such deleterious acid and sulfate attacks lead to expansion and cracking in concrete, and thus, eventually result in damage to concrete matrix by forming expansive hydration products due to the reaction between portland cement hydration products and acid and sulfate ions. Objectives of this experimental research are to investigate the effect of mineral admixtures on the resistance to acid and sulfate attack in concrete and to suggest high-resistance concrete mix against acid and sulfate attack. For this purpose, concretes specimens with three types of cement (ordinary portland cement (OPC), binary blended cement (BBC), and ternary blended cement (TBC) composed of different types and proportions of admixtures) were prepared at water-biner ratios of 32% and 43%. The concrete specimens were immersed in fresh water, 5% sulfuric acid, 10% sodium sulfate, and 10% magnesium sulfate solutions for 28, 56, 91, 182, and 365 days, respectively. To evaluate the resistance to acid and sulfate for concrete specimens, visual appearance changes were observed and compressive strength ratios and mass change ratios were measured. It was observed from the test results that the resistance against sulfuric acid and sodium sulfate solutions of the concretes containing mineral admixtures were much better than that of OPC concrete, but in the case of magnesium sulfate solution the concretes containing mineral admixtures was less resistant than OPC concrete due to formation of magnesium silicate hydrate (M-S-H) which is non-cementitious.

• Korean Journal of Food Science and Technology
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• v.37 no.4
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• pp.513-518
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• 2005

Capillary electrophoresis (CE) method was developed to determine (+)-catechin and (-)-epicatechin contents in grape seed ethanol extract. CE separation was achieved using 100 mM phosphate and borate buffer at pH 6.0 as background electrolyte and fused silica capillary with 50 microns x 375 microns O.D. (effective length 20.0cm) maintained at $25^{\circ}C$. The applied voltage was 10kV, and detection was performed by DAD at 210 nm, Two catechins were well separated within 6 min with repeatability of <0.8% RSD for migration time and <2.0% RSD for peak area, and correlation coefficients higher than 0.994 were obtained from 58.0 to 174.0 mg/L with detection limit of 0.035 mg/L. Separated compounds were successfully determined. CE method was easy to handle and showed good reproducibility. CE method was compared with conventional coloring and HPLC methods, and main advantages of CE method were low amount of sample required, simple pre-sample treatment, good recovery rate, and short analysis time.