• Journal of Veterinary Clinics
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• v.30 no.4
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• pp.223-229
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• 2013

Because colostrum is considered to be the sole source of passively acquired maternal antibodies for calves, newborn calves must consume colostrum to gain disease resistance during their early years of life. Storage of surplus colostrum from dairy cows right after calving and feeding newborn calves in deficiency of colostrum to assure adequate uptake of IgG for protection of the calf has been a common practice in the bovine production. In the current study, 35 colostrums were randomly collected from 3 colostrum banks located in different regions of Korea and monitored for general bacterial contamination and major bovine pathogens. Immunoglobulin concentrations and BVDV-specific antibodies were also determined to evaluate the immune quality of the colostrums. Moderate to severe bacterial contamination (up to 72,000,000 CFU/ml) was observed in most of the colostrums collected from colostrum banks. General immune quality of the colostrums was under the satisfactory level since most of the colostrums contained less than 50 g/L of IgG, which is the minimum concentration for good quality colostrums. Therefore, colostrum for colostrum bank should be collected at the first 2-3 post-partum milkings according to proper harvesting and handling procedures to guarantee the safety and quality of colostrum. In addition, it was recommended that colostrum should be heat-treated before frozen and stored in the bank because pasteurization at $63^{\circ}C$ for 30 min was very effective reducing the risk of disease transmission without causing significant degradation of immunoglobulins.

• Journal of Nutrition and Health
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• v.23 no.3
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• pp.179-186
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• 1990

Nitrogen(N) concentrations of human milk in various fractions, such as total, protein, nonprotein, whey protein and casein were determined at 2-3 days, 1, 2, 4, 6 and 12 weeks of postpartum. significant decreases in total N, nonprotein N, protein N, whey protein N and casein N were found with time postpartum. Total nitrogen decreased from 401mg/dl at 2-3 days to 211mg/dl at 12 week. Whey protein nitrogen was found to contribute to the total nitrogen decrease with time. The percentage of nonprotein nitrogen was 13% in colostrum and 17-18% in mature milk. The proportions of whey protein and casein nitrogen were 55:45 at 2-3 days and 34:66 at 12 week postpartum. These determinations will provide the basic information on the variability of nitrogen components as lactation proceed.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.255-255
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• 1994

MIEF는 소의 초유중에 함유되어 있는 분자량 22,000 dalton의 peptide로서 말초혈액 림파구의 배양액에 첨가할 경우 자연살해세포를 활성화 시켜 암세포에 대한 자연살해능을 증가시키는 것으로 이미 보고된 바 있다. 본 연구에서는 수유기간별 MIEF의 함량 및 MIEF가 B세포의 증식 및 분화에 미치는 영향을 조사하였다. 수유기간별 MlEF의 함량을 competitive ELISA inhibition assay를 이용하여 조사한 결과 MIEF의 함량은 수유 첫째날의 초유에 109$\mu\textrm{g}$/ml로 가장 높았으며, 그 이후로 급격히 감소하여 3일째 이후에서는 3-4$\mu\textrm{g}$/ml이하로 존재하였다. MIEF가 B세포의 분화에 미치는 영향은 사람의 편도선에서 분리한 림파구의 배양액에 MIEF를 가하고 5-9일간 배양한후 항체를 생산하는 세포의 수를 ELISPOT assay로 측정하여 조사하였다. MIEF는 10-30$\mu\textrm{g}$/ml의 농도에서 B세포의 분화를 촉진시켰으며, 그 정도는 양성대조군으로 사용한 LPS와 유사하여 MIEF가 B세포의 분화를 유도하는 작용이 아주 강력함을 알수 있었다.

• Journal of Animal Science and Technology
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• v.51 no.2
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• pp.163-170
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• 2009

Colostrum provide a complete diet for the newborn calves. In ruminants, colostrum is also the sole source of initial acquired immunity for the offspring. Colostrum, therefore, plays an important role in ruminants host defense. Bovine colostrum imparts passive immunity to newborn calves during the first 24h of life and generally has been fed for the first 3 days after birth. Colostrum can be preserved conveniently for future use by brief refrigeration, freezing, or storage at ambient temperatures (fermentation or chemical treatment). Colostrum management were surveyed via data collection from 67 dairy farms in Gyeonggi and Chungnam provinces. After parturition for five days the total amount of produced colostrum was 80.4 kg on average, and the average amount of lactation fed to a calf was 20.9 kg. According to the survey results, identified treatment methods for surplus colostrum are as follows; disposal 17.9%, other calf feeding 37.3%, storage 22.4%, other livestock feeding 20.9% and other treatment 1.5%. For improvement in the quality of colostrum, there must be controlled usage of medicines (such as antibiotics) before and after parturition, proper choices of milk-drying agents, and increased milking yields during the early stage of the milking period.

• 우유
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• s.62 fall
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• pp.13-20
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• 1995

우유는 건강한 소의 유미관에서 분비되는 것으로 초유는 포함되지 않으며 어린이의 발육과 성장에 필수적인 영양소가 풍부하게 포함되어 있는 완전식품으로, 그대로 마시거나, 소스 · 수프 · 육류요리 · 비스켓 · 케이크 등의 재료로 이용되며, 이 우유를 원료로 해서 버터 · 치즈 · 크림 · 발효유 · 아이스크림과 같은 유가공품 으로서도 널리 이용된다. 우리나라 식생활에서는 식품섭취영태는 당류의 섭취도가 높고, 단백질이나 칼슘급원식품의 섭취가 부족한 상태이므로 우유를 칼슘의 급원식품으로 한 사람이 매일 1컵 이상의 우유를 섭취하도록 권장하고 있다. 특히 성장기의 어린이를 위하여는 학교급식에서 싼 가격으로 우유를 먹을 수 있도록 배려하며 하루 3~4컵의 우유를 섭취할 것을 권장하고 있다. 이와 같은 시점에서 본고에서는 우유와 유가공품을 선택하여 먹고 마시는 경우에 그 식품 본래의 영양성분과 맛을 잃지 않고 섭취할 수 있는 효과적인 방법과 보관할 때의 주의할 점과 언제 먹고 마시는 것이 효과를 증진할 수 있는지 등을 알아보고자 한다.

• Journal of Embryo Transfer
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• v.33 no.3
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• pp.159-168
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• 2018

Bovine colostrum is necessary for newborn calves to survive, grow and receive immunity from their mother. Cows in Korea produce about 35kg of colostrum, 4Kg of which is fed to the calf, and the rest is discarded. The bovine colostrum causes the harmful side effects to human, such as allergies and digestive problems; so, it is prohibited by law to consume colostrum itself as a food. However, many scientific research data have suggested that components in the colostrum can improve human health and has the ability to help treat diseases. In line with the trend of food and pharmacy industries using natural product materials, which attract positive attention, recently, some ingredients in colostrum have been used in the production of food supplements, and it has been used in its raw form in some cosmetics. This review introduces the active ingredients and physiologically active substances contained in bovine colostrum, summarizes the efficacy of physiological enhancement of the colostrum, which has been proven by scientific methods to date, and also suggests the possibility of industrial applications of colostrum as an animal-derived natural material.

• Korean Journal of Veterinary Service
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• v.31 no.4
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• pp.533-546
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• 2008

The efficacy of bovine immune sera to correct the calves with failure of passive transfer(FPT) was evaluated. Immune sera were produced from 14 one-year-old Holstein cattle which were inoculated commercial combined viral vaccine, administered by the challenge of some main enteric or respiratory viruses, aseptically filtered and stored at $4^{\circ}C$ before used. After the treatment of bovine immune sera, Mean transfer factor($mg/d{\ell}$, of IgG administered/kg of body weight) was $5.46{\pm}2.74,\;11.17{\pm}1.27,\;1.40{\pm}0.21$ in K-IP, H-IP and K-IV group, respectively. The corrective effect of bovine immune sera to FPT calf without any clinical signs showed that intravenous route was more effective than intraperitoneal administration(P<0.01). FPT calves with severe signs were not effective response to the immunotherapy used and consequently died within 10 days after the treatment. Ten percentage of controls appeared the clinical signs including diarrhea. On the contrary, there were not any clinical signs in K-IP and H-IV group. There was significant increase of the neutralizing titer against bovine viral diarrhea virus and bovine coronavirus as well as of cell population including CD2, CD4, and monocyte in K-IP and H-IV group after the immunotherapy(P<0.05). Also, K-IP and H-IV group showed the successful correction to FPT within one week after the immunotherapy, but controls had kept the FPT two-four weeks even after the same treatment. Consequently, the results were suggesting that the bovine immune sera could be used the corrective tool to young calves with FPT.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.60-60
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• 2023

태풍 힌남노에 경주에 위치한 총저수량 184만m³, 유역면적 22km²인 왕신저수지는 303m의 제체가 2시간여 동안 전면 월류하는 초유의 사태를 겪었다. 그때 다행히 저수지 수위는 10분 단위로 기록됐다. 이 자료를 이용하여 제체 월류현상을 평가하기 위해 저수지 운영의 기본자료인 유입량, 저수량, 방류량 등을 10분 단위로 생산코자 했다. 방법은 인근에 위치하고 운영자료가 있는 총저수량 260만m³, 유역면적 3.7km²인 감포댐에 대해 유입량 모의방법을 검증하고, 왕신저수지에 그대로 적용하여 유입량을 모의하고, 물수지에 의해 방류량을 계산하는 것으로 했다. 모의결과는 저수량 오차로 신뢰도를 확인했다. 여기서 저수지 유입량은 ONE 모형을 이용하여 10분 단위로 생산했다. 2022년 9월 5일부터 6일까지 10분 단위로 모의한 결과는 다음과 같다. 첫째, 감포댐 유역은 강우량은 10분 최대 32.3mm, 총강우량 196.0mm였고, 유입량은 10분 최대 80.1m³/s, 총유입량 59만m³로 모의됐고, 신뢰도는 RMSE 2.120mm, NSE 0.947, R²는 0.949로 매우 높게 나타났다. 그리고 저수량 모의 신뢰도도 RMSE 0.153m, NSE 0.993, R²는 0.997로 높았다. 둘째, 왕신저수지 유역은 강우량은 유역내에 위치한 환경부 관리의 화산리 관측소에서 10분 최대 21.0mm, 총강우량은 10시간 동안 422.0mm였고, 유입량은 10분 최대 716.5m³/s, 총유입량 904만m³로 모의됐고, 유출률은 95.7%로 강우량 거의가 유입되는 것으로 나타났다. 셋째, 왕신 저수지의 방류량은 10분 최대 610.8m³/s, 총방류량 848만m³로 계산됐고, 총유입량의 93.8%에 상당한 것으로 나타났다. 그리고 저수지 물수지에 의해 10분 단위 모의 저수위의 신뢰도는 RMSE 0.117m, NSE 0.994, R²는 0.999로 매우 높게 나타났다. 넷째, 왕신저수지의 제체고 EL.59.20m를 월류한 시간은 9월6일 5시50분부터 8시까지 2시간10분 동안였으며, 관측 저수위는 EL59.24m~EL.60.28m, 모의 저수위는 EL.59.31m~EL.60.29m로 나타났다. 월류되는 동안 총유입량은 544만m³, 총방류량은 527만m³로 나타나, 유입량의 96.8%가 월류되는 것으로 계산돼 저수지의 저류효과는 거의 없는 것으로 나타났다. 이때 유입량은 전기간의 60.2%, 방류량은 62.1%에 상당했다. 다섯째, 힌남노에 따른 왕신저수지의 홍수조절효과는 첨두유입량을 105.7m³/s 저감시켰고, 홍수량을 56만m³을 저류시킨 것으로 분석됐다.

• Cartoon and Animation Studies
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• s.45
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• pp.197-214
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• 2016

Augmented Reality, virtual reality in recently attracted attention throughout the world. and Mix them mixed reality etc., it has had a significant impact on the overall pop culture beyond the scope of science and technology. The world's leading IT company : Google, Apple, Samsung, Microsoft, Sony, LG is focusing on development of AR, VR technology for the public. The many large and small companies developed VR hardware, VR software, VR content. It does not look that makes a human a human operation in the cognitive experience of certain places or situations or invisible through Specific platforms or program is Encompass a common technique that a realization of the virtual space. In particular, out of the three-dimensional image reveals the limitations of the conventional two-dimensional structure - 180, 360 degree images provided by the subjective and objective symptoms such as vision and sense of time and got participants to select it. VR technology that can significantly induce the commitment and participation is Industry as well as to the general public which leads to the attention of colostrum. It was introduced more than 10 related VR works Year 2015 Sundance Film Festival New Frontier program. The appearance VR content : medical, architecture, shopping, movies, animations. Also, 360 individuals can be produced by the camera / video sharing VR is becoming an interactive tunnel between two possible users. Nevertheless, This confusion of values, moral degeneration and the realization of a virtual space that has been pointed out that the inherent. 4K or HUD, location tracking, motion sensors, processing power, and superior 3D graphics, touch, smell, 4D technology, 3D audio technology - It developed more than ever and possible approaches to reality. Thereafter, This is because the moral degeneration, identity, generational conflict, and escapism concerns. Animation is also seeking costs in this category Reality. Despite the similarities rather it has that image, and may be the reason that the animation is pushed back to the VR content creation. However, it is focused on the game and VR technology and the platform that is entertaining, but also seek new points within the animation staying in the flat Given that eventually consist of visual images is clear that VR sought. Finally, What is the reality created in the virtual space using VR technology could be applied to the animation? So it can be seen that the common interest is research on what methods and means applied.