• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.99-99
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• 2019

한국생명공학연구원 해외생물소재센터는 해외생물소재 확보 및 활용연구를 통하여 차세대 국가핵심전략 BT산업의 필수원자재인 생물소재의 범지구적 확보와 보존 관리의 임무를 수행하고 있다. 이를 위해 권역별 해외생물소재 공동연구센터(중국, 코스타리카, 인도네시아, 베트남) 및 37개국과의 국제협력 네트워크를 구축하고 있다. 세계적 수준의 생물소재 국가 인프라 구축을 목표로 국내 산 학 연 연구자들에게 다양한 해외생물소재 공급을 통한 지속 가능한 바이오 경제 기반 구축을 지원하고 있다. 해외생물소재센터에서는 2006년부터 특히 천연물 의약품 개발 분야에 많이 사용 되고 있는 해외 식물소재를 지속적으로 확보하고 있으며, 확보된 식물소재의 추출물 제조 및 추출물 은행을 구축, 이에 대한 생물활성 평가를 실시하며 연구자들에게 기초 자료로 제공하고 있다. 현재까지 총 36,500종의 해외식물소재를 확보하였으며, 추출물 약 320만점을 확보하였다. 확보된 소재의 분양활동을 통해 산 학 연 연구자들에게 180만여 점을 분양하였으며, 이를 활용한 다수의 논문과 특허를 획득하였고 중대형 기술이전을 실시하였다. 해외생물소재센터는 홈페이지 기반 분양 신청 시스템[https://www.ibmrc.re.kr]을 통하여 해외식물소재(Powder 와 Extact 형태) 분양서비스를 제공하고 있다. 또한 소재가치제고 연구를 통한 산업화 지원과 해외생물소재의 표본정보 서비스, 해외거점센터를 활용한 현지정보 제공 서비스를 지원하고 있다.

• Korean Journal of Food Science and Technology
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• v.38 no.6
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• pp.779-784
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• 2006

To produce bio-active Kochujang, 1.2% of pomegranate powder, 1.0% of hawthorn berry extract powder, 0.01% of ginko biloba extract, 1.2% of red yeast rice powder, 1.2% of silk powder, 0.2% of garlic oil, 0.2% of chitosan, 1.2% of wax gourd extract powder, and 1.0% of pine mushroom were added individually with raw materials that are needed for Kochujang process. These Kochujangs were fermented for 45 days at $30^{\circ}C$, and examined for changes in their physicochemical properties. There were no significant differences in pH, acidity, formol-N content, color and total cell count by plate count agar between Kochujangs fortified individually with functional ingredients and the control Kochujang. When 0.2% of garlic oil was added, antioxidant activity of its Kochujang product increased twice as much as that of the control Kochujang. Improved ACE inhibiting activities were observed in 1.2% of red yeast rice powder. When 1.2% of silk powder or 0.01% of ginko biloba extract were added, antithrombotic abilities were remarkably enhanced up to two times of the control Kochujang.

• Journal of Digital Convergence
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• v.12 no.11
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• pp.159-169
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• 2014

I Bank, which is domestic one, has implemented a performance management system based on the balanced scorecards (BSC). The purpose of this study is to understand the status and seek improvements of the performance management system of the bank. To achieve the purpose, this paper makes study about the earlier researches and does empirical study based on the questionnaire survey analysis. After figuring out issues, this paper proposes improvements to operate the performance management system using BSC more properly. The Journal of Digital Policy & Management. This space is for the abstract of your study in English.

• Proceedings of the KGS Conference
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• 2004.05a
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• pp.72-72
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• 2004

최근 수십 년 간 인류의 삶 전체에 획기적인 변화를 가져온 정보통신 기술의 발달은 금융정보화의 급속한 진전을 가져왔다. 이는 금융업무의 전산화는 물론이고, CD/ATM기(이하 자동화기기)ㆍ전화ㆍ인터넷 핸드폰 등 다양한 매체를 이용한 금융서비스 채널의 등장을 통해 나타난다. 금융서비스의 제공이 과거 점포 위주의 단일 채널에서 탈피하여 다양해 가는 것은 단순히 금융시스템상의 변화를 넘어 금융활동의 기반이 되는 공간에도 중요한 영향을 미치게 된다. (중략)

• Journal of the Korean Applied Science and Technology
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• v.38 no.5
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• pp.1229-1240
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• 2021

Ginkgo (Ginkgo biloba L.) seeds, called 'Baekqwa', were extracted from 70% ethanol to investigate the whitening effect and to confirm the application potential as a cosmetic material. Ginkgo seed ethanol extracts (GBE) were treated with B16F10 melanoma cells, and melanin contents and tyrosinase, which is the main enzyme concerning the synthesis process of melanin, inhibitory activity were confirmed. As a result, there were inhibited in a concentration-dependent manner, and GBE also significantly reduced the protein expression and mRNA levels of tyrosinase, tyrosinase-related protein-1, -2 (TRP-1, -2), and their upstream transcription factor, microphthalmia-associated transcription factor (MITF). These results suggest that GBE could be used as an effective whitening agent that has an inhibitory effect on melanin production by regulating the expression and degradation of MITF in melanocytes.

• Prospectives of Industrial Chemistry
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• v.14 no.4
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• pp.29-40
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• 2011

앞으로 글로벌 시장에 진입할 수 있는 작물보호 신물질 개발을 위해서는 기술 난이도가 크면서 파급성 및 경제성을 갖는 친환경 신규작용점 탐색과 독창적 Scaffold를 갖는 후보물질 또는 천연물소재 발굴에 주력해야 하며, 이를 지원하는 HTS, 화합물은행 및 천연물은행 활용 분자설계 및 최적화 합성기술 등 후보물질 발굴 핵심 기술개발에 국가적인 지원이 지속적이고 장기간에 걸쳐 이루어져야 한다. 고품질의 식량생산 관리기술은 물론 석유대체 에너지 확보를 위한 농작물 바이오매스(작물, 사료, 바이오연료 등) 생산관리기술로서, 그린바이오기반(Target 효소, 천연물소 재탐색응용) 저탄소 녹색성장을 실현시키기 위한 친환경적인 생화학 작물보호제 개발이 필요하다. 또한 인구 증가와 유가상승 등 전 세계적인 경제위기 극복과 이산화탄소 증가에 따른 온난화 등 지구환경보존의 중요성이 크게 증가되면서 안전한 먹거리 생산과 환경오염을 최소화하는 지속적 생산체제를 갖추기 위하여 LOHAS (Lifestyle Of Health And Sustainability) 트랜드가 최근 농업의 화두로 떠오르고 있다. 이를 만족시키기 위하여 OECD를 중심으로 하는 선진 국가들은 기존 작물보호제의 사용을 5년 이내에 현재 사용량의 절반 이하로 감소시키고자 하고 있는데, 특히 지속적 재배와 국민건강 보호를 위한 LOHAS 농작물의 생산이 매년 50-100억불로 성장하고 있다. 이러한 추세는 2017년까지 그 성장세가 계속 지속될 것으로 예상되고 있어 미생물/생화학 중심의 바이오작물보호제의 개발은 LOHAS 트랜드를 충족시킬 수 있는 유력한 수단으로 인식되고 있다.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2020.12a
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• pp.77-77
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• 2020

본 연구에서는 비트 새싹 추출물의 항산화 및 항염증 효능을 평가하기 위해 3가지 품종의 레드 비트(메를린, 우단, 디트로이트다크레드) 새싹을 60% 에탄올로 추출한 후 free radical 소거활성, 총 폴리페놀 함량을 측정하였다. 또한, LPS로 염증반응이 유도된 대식세포인 RAW264.7 세포에서 nitric oxide(NO) 생성억제 효과를 알아보았다. 메를린, 우단, 디트로이트다크레드 새싹 추출물의 총 폴리페놀 함량을 querceitn을 표준물질로 사용하여 측정한 결과 2.84 mg Que/g, 2.61 mg Que/g, 2.71 mg Que/g으로 나타났고 DPPH 라디칼 소거능은 농도 의존적으로 증가하였으며, 200 ㎍/ml일 때, 55%, 72%, 63%로 나타났다. 또한, DPPH 라디칼 소거능이 가장 높은 메를린 새싹 추출물은 LPS로 염증반응이 유도된 RAW264.7 세포에서 농도 의존적으로 iNOS와 COX-2를 억제하는 것을 확인하였다. 이러한 결과를 바탕으로 메를린 비트 새싹 추출물이 항산화 및 항염증제의 천연물 소재로 활용이 가능할 것으로 생각된다.

• Korea Trade Review
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• v.43 no.4
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• pp.89-110
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• 2018

This paper reviews the practical operations and exceptions to the independent principle by analyzing the leading cases of English documentary credit transactions. A bank's undertaking in L/C transactions differentiates between underlying contract and other contracts. The autonomy principle is the key principle governing L/C, but this principle may be connected with unfair (unjust) payment. English Law is strongly influenced by the developments in American Law in the case of fraud, but traditionally, British courts has been very reluctant to interfere in banks' independent undertaking under the L/C. The position of British case law relating to fraud is based on Sztejn. In practice, British courts recognize fraud as an exception to the autonomy principle in which the case is sufficiently serious to render it unjust to permit the beneficiary to receive payment. British case law has historically taken a narrow approach toward intervention in the independent principle of documentary credit. Therefore, innocent parties including beneficiaries are protected by these regulations regarding fraud.

• Journal of Industrial Convergence
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• v.22 no.2
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• pp.1-12
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• 2024

This study investigates what decisions have an impact on bank performance. A panel regression analysis was conducted using data from the financial statements of banks located in the United States from 2013 to 2022, and the effects of explanatory variables were examined through hierarchical panel regression analysis divided into financial decision-making and management decision-making. In addition, by analyzing performance separately from the creditor and shareholder perspectives (hereinafter referred to as overall) and from the shareholder perspective alone, it suggests which elements should be utilized and how to improve performance from each perspective. When a panel regression analysis was performed using only liquidity and stability, dependency on deposits and the interest coverage ratio had a statistically significant impact from the perspective of overall performance, and the debt ratio also had a statistically significant impact from the perspective of shareholder performance. When adding non-technical factors, only the labor cost ratio among non-technical factors was found to be statistically significant from the overall performance perspective, and although the non-technical factors were not statistically significant from the shareholder performance perspective, the cash ratio was found to have a statistically significant impact. Lastly, when adding technical innovation elements, the intangible asset ratio was not statistically significant from the overall performance perspective, but was significant from the shareholder performance perspective. The significance and implications of this study are that there are differences in factors that can affect the performance of overall or shareholder and that various decision-making factors can affect a bank's performance.

• Korean Journal of Poultry Science
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• v.37 no.1
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• pp.23-33
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• 2010

The current study was performed to develop natural bio-active substances as additives for the production of high quality broiler chickens. A total of 120 male 3 day-old broiler chicks were randomly allocated to CON (control), GK2.5 (ginkgo leaf 2.5%), GK5.0 (ginkgo leaf 5.0%), PK2.5 (pumpkin 2.5%) and PK5.0 (pumpkin 5.0%) of five groups in cages (24 birds per group). All birds were fed corresponding diets from 3 to 35 d of age and determined growth performance and biological parameters including blood biochemical profiles, antioxidant status and intestinal microflora. During the entire feeding trial, GK5.0 and PK5.0 groups resulted in a significantly (P<0.05) higher FCR than GK2.5 and PK2.5 groups. Plasma triglyceride significantly (P<0.05) increased in GK5.0 group compared with the other groups, and the level of alanine transaminase (ALT) increased (P<0.05) in GK5.0 and PK5.0 groups compared with that in PK2.5 group. Dietary addition of ginkgo leaf and pumpkin significantly (P<0.05) increased superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the small intestine. Also, the addition of 2.5% ginkgo leaf significantly (P<0.05) increased the activities of SOD, GSH-Px and glutathione-S-transferase (GST) in the liver. Futhermore, muscle GST activity significantly (P<0.05) enhanced by dietary addition of ginko leaf and pumpkin. However, the level of lipid peroxidation (MDA) in the small intestine and muscle turned to be higher (P<0.05) in PK5.0 group. The colony forming units (CFU) of E. coli in intestinal digesta significantly (P<0.05) decreased in both ginko leaf and pumpkin supplemented groups compared with CON group. In conclusion, dietary addition of 2.5% ginko leaf and pumpkin as dietary sources can be applicable for the production of high quality broiler chickens.