• Title/Summary/Keyword: 셀레나

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Effects of Exercise Training and Selenium on MCT1 and MCT4 Protein Levels in Skeletal Muscles of Diabetic Goto-Kakizaki Rats (지구성 운동과 셀레니움 투여가 당뇨 Goto-kakizaki 쥐의 골격근의 MCT1과 MCT4단백질 발현수준에 미치는 효과)

  • Kim, Seung-Seok;Kang, Eun-Bum;Eum, Hyun-Sub;Kim, Bum-Su;Lim, Yea-Hyun;Park, Joon-Young;Cho, In-Ho;Oh, Yoo-Sung;Kwak, Yi-Sub;Cho, Joon-Yong
    • Journal of Life Science
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    • v.18 no.1
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    • pp.1-8
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    • 2008
  • The purpose of this study was to determine the possible additive effects of endurance exercise training (EXER) and selenium (SELE) on the improvements of glucose and lactate transport capacities in diabetic Goto-kakizaki rats. Animals either remained sedentary control (SED) or performed EXER or received SELE [$5{\mu}mol$ kg body wt (-1) day (-1)], or underwent both EXER and SELE (COMBI), which lasted for 6 wk. Compared with sedentary control, EXER alone or the SELE alone group, or the combined treatment group had significant reduction in glucose response measured at 90 min and 120 min during an intraperitoneal glucose tolerance test (IPGTT) and body weight after 6week treatment. EXER alone, or combined group individually had significantly higher glycogen contents in liver compared with SED or SELE groups. EXER alone increased glycogen content in soleus and plantaris compared with SED, and this parameter was increased to greatest extent in the combined treatment groups compared with SED or SELE groups. EXER alone, SELE alone or COMBI, caused significant decreases in the plasma lactates, serum glucose, insulin, total cholesterol and HOMA-IR along with a significant increase in high-density lipoprotein cholesterol compared with SED. In addition, EXER or COMBI individually had significantly lower serum triacylglycerol compared with SED or SELE. With respect to protein expression related to glucose and lactate transport capacities, EXER alone, SELE alone, or COMBI increased in MCT1 and MCT4 protein level in soleus and plantaris. Furthermore, EXER alone, SELE alone or COMBI caused significant increases in mt MCT1 protein level in soleus and plantaris. The findings of the current study suggest that endurance exercise training and selenium treatment may provide therapeutic values to type II diabetic patients with peripheral insulin resistance and hyperlactatecemia by improving glucose and lactate transport capacities, leading to improvements in plasma lactate, serum glucose, insulin and lipid profiles (TC, TG, HDL).

Changes in Body Composition of Protaetia brevitarsis seulensis Larvae Fed Sulfur and Selenium (황 및 유황 급이에 따른 흰점박이꽃무지 유충의 체성분 변화)

  • Park, Cheol Jin;Kang, Ho In;Kim, Sam Woong;Bang, Kyu Ho;Kim, Tae Wan;Kim, Hyun-Wook;Kim, Il-Suk
    • Journal of Life Science
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    • v.32 no.6
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    • pp.455-462
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    • 2022
  • This study examined changes in the body composition of Protaetia brevitarsis larvae fed sulfur and selenium. Among the general chemical components, an increase in protein was observed in the sulfur-fed group, whereas an increase in fatty acid was found in the groups fed selenium and sulfur/selenium. The structural amino acid showed some tendency to be increased compared to the control group, but this was especially true in the sulfur-fed group. The free amino acid were increased in the groups fed selenium and sulfur/selenium, with GABA, Glu, and Pro, in particular, being increased in the group fed sulfur/selenium. Among the essential amino acids, Met, Trp, and Val tended to be increased in selenium and sulfur/selenium groups. Saturated and polyunsaturated fatty acids showed a tendency to increase in the group fed sulfur/selenium, but monounsaturated fatty acid tended to be decreased in the group. In particular, no oleic acid was detected in the sulfur/selenium group, whereas palmitic acid, palmitoleic acid, and linoleic acid were increased. From observations of these body composition changes associated with the feeding of sulfur and selenium, it is estimated that the group fed sulfur/selenium would likely undergo a pronounced change in body composition. Therefore, we suggest that it is possible to manufacture a food that has enhanced functionality by appropriately adjusting the diet of Protaetia brevitarsis larvae.

Association between Cancer and Selenium Concentration in Blood and Toenails (혈액과 발톱의 셀레니움 농도와 암과의 관련성)

  • Rhee, Jung-Kil;Chung, Jong-Hak;SaKong, Jun;Kang, Pock-Soo;Kim, Chang-Yoon;Lee, Kyeong-Soo;Kwun, Koing-Bo
    • Journal of Yeungnam Medical Science
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    • v.9 no.1
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    • pp.29-43
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    • 1992
  • A case-control study was conducted to investigate the association between the risk of cancer and selenium concentration in blood and toenails. Seventy three patients and two hundreds eighty three controls were, selected at the Yeungnam University Hospital between May and September in 1991. The selected cases were patients who had been hospitalized for stomach or colon cancer at the Depertment of General Surgery. The controls were people who visited to check physical examination at the Automated Mediscreening Center. The selenium concentration in whole blood and toenails were measured by atomic absorption spectrophotometer equipped with graphite furnace atomizer. The following information was ascertained for all cancer patients and controls : sex, age, body mass index, blood pressure, total serum cholesterol, and history of smoking and drinking. The mean selenium concentration in blood and toenail for all cancer patients were $143.6{\pm}10.8{\mu}g/l$ and $1.04{\pm}0.62{\mu}g/g$ and for the controls, $167.0{\pm}14.5{\mu}g/l$ and $1.15{\pm}0.55{\mu}g/g$, respectively. The difference in blood and toenail selenium concentrations of the two cancer sites was not statistically significant. Metastasis did not influence the concentration of selenium in blood and toenails. In the multiple logistic regression analysis, the blood selenium concentration($_aOR$: 0.888, 95% CI : 0.860-0.918), age, BMI and total serum cholesterol were significant variables for risk of cancer, but the selelenium concentration in toenail was not shown to be a significant variable in this regression analysis. The coefficient for blood selenium concentration adjusted for age, sex, diastolic blood pressure, total serum cholesterol, body mass index and smoking was -0.1184(p<0.01). These findings suggest that low selenium concentration is associated with gastrointestinal cancers. Further epidemiologic studies including important variables such as other antioxidant micronutrients will be necessary.

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Interaction between Selenium and Bacterium and Mineralogical Characteristics of Biotreated Selenium (셀레늄-미생물간의 반응 및 셀레늄 광물화 특성)

  • Lee, Seung-Yeop;Oh, Jong-Min;Baik, Min-Hoon
    • Journal of the Mineralogical Society of Korea
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    • v.24 no.3
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    • pp.217-224
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    • 2011
  • Removal of dissolved selenium by D. michiganensis, a iron-reducing bacterium, and effects of dissolved metal elements such as iron, sulfate, and copper were investigated. Selenide that was reduced from selenite (2 mM) by D. michiganensis was gradually removed from the aqueous medium. As the reduced selenide was combined with aqueous iron, it was precipitated as a nanoparticulate iron-selenide. Sulfate and copper negatively affected the microbial selenite reduction, and the copper was especially toxic to the bacterium, inhibiting a microbial removal of dissolved selenite. These results show that it should be carefully biotreated for a selenium-contaminated site considering in situ sulfate or copper distribution and concentration. Consequently, the formation of iron-selenide by bacteria will be an important measure for preventing a long-distance migration of selenium in the subsurface environments.

Determination of optical constants of selenide glasses of Ge-Sb-Ga-Se system using spectroscopic ellipsometry (분광타원법을 이용한 Ge-Sb-Ga-Se 계열 셀레나이드 유리의 광학상수 결정)

  • 신상균;김상준;김상열;최용규;박봉제;서홍석
    • Proceedings of the Optical Society of Korea Conference
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    • 2003.07a
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    • pp.34-35
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    • 2003
  • 광통신 분야에서 광신호의 장거리 전송에 따른 세기 감소를 보강하기 위해 쓰이는 광섬유증폭기는 현재 1.3 $\mu\textrm{m}$ 대역, 1.45 $\mu\textrm{m}$ 대역 및 1.5 $\mu\textrm{m}$ 대역에서 작동하는 희토류 이온 첨가 광섬유 광증폭기가 개발되어 쓰이고 있다. 한편 ETRI에서는 기존 광통신에 쓰이는 광 증폭기에 추가해 더 넓은 파장대를 광통신에 쓸 수 있도록 하는 새로운 파장대역의 광 증폭기 구현을 가능케하고 나아가 광통신 용량을 기존보다 휠씬 더 큰 10 Tbps급 이상으로 늘이기 위해 1.6 $\mu\textrm{m}$ 파장대인 U 밴드대 광증폭기용 광섬유인 Pr 첨가 셀레나이드 유리 조성의 신소재를 개발하였는데, 본 연구에서는 Ge-Sb-Ga-Se 계열의 Pr 첨가 셀레나이드 유리의 굴절률을 분광타원 법 (spectroscopic ellipsometry)을 사용하여 결정하였다. (중략)

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최신의학상식 - 갑상선 호르몬과 요오드

  • Kim, Yong-Seok
    • KOREAN ASSOCIATION OF OCCUPATIONAL HEALTH NURSES
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    • v.18 no.2
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    • pp.17-24
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    • 2011
  • 갑상선 호르몬은 2가지 형태, 즉 L-thyroxine(tetraiodothyronine, T4)과 L-triiodothyronine(T3)으로서 갑상선(thyroid gland)에서 합성된다. 요오드는 갑상선 호르몬의 핵심요소이며 음식물에 포함된 요오드는 섭취 후 소장에서 흡수되어 혈류를 통해 갑상선으로 운반되고, 갑상선에서 농축, 산화되어 thyroglobulin이라는 단백질의 구성 아미노산 중 tyrosine에 삽입됨으로써 T4와 T3를 생성하게 된다. 갑상선 호르몬의 합성에는 요오드 이외에도 셀레니움이 필수적이다. 요오드와 셀레니움은 미량원소로서 부족하면, 갑상선 호르몬 결핍 또는 갑상선 비대를 초래할 수 있다.

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Effects of Selenate Ion Concentration in Nutrient Solution on the Growth and Essential Oil Content of Wormwood( Artemisia absinthium L.) (배양액 내의 Selenate 이온농도가 웜우드(Artemisia absinthium L.)의 생육 및 정유함량에 미치는 영향)

  • Park, Kuen-Woo;Lee, Yun-Jeong;Jeong, Jin-Cheol
    • Journal of Bio-Environment Control
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    • v.6 no.4
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    • pp.264-269
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    • 1997
  • This study was conducted to evaluate appropriate selenate ion concentration for the production of high functional vegetables. Sodium selenate was treated 0, 2, 4, 6 and 8mg/$\ell$ using herb nutrient solution developed by European R & D Vegetable Center in Belgium. Low level of Na2se04 concentration increased the growth of wormwood, but high selenate concentration decreased the growth. Total chlorophyll content was increased by sodium selenate. The higher selenate ion concentration in the nutrient solution, the more total chlorophyll content was. The vitamin C content in wormwood was high at 2 and 4mg/$\ell$ treatment, showing good growth, at higher concentration, however, the vitamin C content decreased. At 4mg/$\ell$ selenate ion concentration, essential oil content of wormwood was best. But higher selenate ion concentration decreased essential oil content. The uptake of Se by the plant increased with the increase of selenate ion concentration.

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Development of Remote Control Module on a 3D Universe Visualization (3D 우주환경 가시화 도구 원격 제어 모듈 개발)

  • Han, Sang-Hyuck;Koo, Cheol-Hea;Lee, Hoon-Hee;Moon, Sung-Tae
    • Aerospace Engineering and Technology
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    • v.12 no.1
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    • pp.120-127
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    • 2013
  • Recently, In Aerospace area the interest of open source software is increasing. One of examples is celestia that is used for visualizing space environment with 3D. Celestia that is open source software has many advantages. First is very easy to use, second is that it can extend new features easily with script language. It is very useful to extend with other systems. But, celestia has a few of remote control features from remote site. In this paper I describe design and implementation of remote control module using UDP communication protocol between celestia and GenSim that is satellite simulation software developed by KARI and describe the problem and solution items are found during development duration.

Effects of Selenate and Sulfate Ion Interaction in Nutrient Solution OH the Growth Of Artemisia molngotica var. tenuifolia (배양액 내의 Selenate 와 Sulfate 이온의 상호작용이 참쑥의 생육에 미치는 영향)

  • Lee, Yun-Jeong;Park, Kuen-Woo;Suh, Eun-Joo;Cheong. Jin-Cheol
    • Journal of Bio-Environment Control
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    • v.7 no.1
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    • pp.63-70
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    • 1998
  • This study was carried out to investigate the interaction of selenate and sulfate ion in nutrient solution supplyed with selenate ion. At early growth stage, the growth of Mongolian wormwood was best at 3mM sulfate ion and 2mg/$\ell$Na$_2$SeO$_4$ treatment. As they were grown and matured, at the later growth stage, the effect of antagonism between selenate and sulfate ion on the growth of each plant decreased. At supplying with selenate ion in nutrient solution, the uptake of selenate by plant had negative correlation with sulfate ion concentration in nutrient solution. The higher sulfate ion concentration, the less selenium uptake. However, the effect of antagonistic interaction of selenate and sulfate ion on the selenium uptake increased with plant age. Whereas, the uptake of sulfate ion had positive correlation with sulfate ion concentration in nutrient solution at supplying with selenate ion in nutrient solution. The uptake of sulfate ion increased with increase of sulfate ion concentration in nutrient solution. The effect of this interaction with selenate and sulfate ion increased with growth and maturity of plant. However, at 3mM sulfate ion concentration in nutrient solution, sulfate ion concentration in plant tissue decreased markedly.

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