• Korean Journal of Clinical Pharmacy
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• v.10 no.1
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• pp.1-6
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• 2000

백내장 수술 추 염증치료를 위해 일반적으로 부작용이 많은 국소 점안 스테로이드를 사용해왔다. 최근 NSAID계열의 점안액이 항염증 치료약물로 개발되면서 선택적인 약물치료가 가능하게 되었으나 단일치료약물로 사용하는 경우는 드물다. 본 연구는 NSAID계 diclofenac 점안액의 백내장 수술 후 염증치료 효과를 스테로이드체 dexamethasone 점안액과 비교하여 단일 치료약물로서 사용할 수 있는 지 연구하고자하였다. 백내장 수술을 받은 환자로서 안압이 22 mmHg 이상 당뇨환자, 수술대상 눈에 이미 질환 및 수술 경력이 있는 자를 제외하였다. 백내장 수술 후 항염종 약물로서 diclofenac 또는 dexamethasone을 28일 동안 투여하고 항염증효과의 평가를 위하여 세극등 검사로저 전방내 염증세포와 결막, 각막등의 전안부 관찰을 수술 전, 수술 후 1, 3, 7, 14, 28일에 시행하였고, 시력검사는 수술 추 7, 28일에 시행하였다. 안전성의 평가는 안압검사와 세극등 검사상 관찰된 이상소견으로 평가하였다. 총 73명의 연구대상 중 dexameasone군은 41명, diclofenac군은 32명이며 두 군간에 나이, 백내장의 심한 정도, 안구질환 등에 있어 유의한 차이가 없었다 전방내 항염증세포수의 감소에서 두 군간에 유의할 만한 차이가 없었고, 수술 후 최대 교정 시력에서도 동일한 효과를 보였다. 안전성에서 안압의 상승이 두군간에 통계적인 유의한 차이를 보이지 않았으나 dexamethasone군에서 1명의 환자가 45 mmHg 이상 증가하여 약물치료가 필요하였으나 diclofenac군에서는 안압이 상승한 환자가 없었다. 결론적으로 효능 및 안전성에서 두 약물간에 통제적, 임상적으로 유의한 차이가 없었으며 diclofenac 점안액은 백내장 수술 후 항염증치료제로서 충분한 효과가 있으며 안압상승, 감염 등 부작용이 우려되는 dexamethasone점안액의 대체약물로 사용될 수 있을 것으로 평가된다.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.2
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• pp.59-64
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• 2000

We performed refraction, keratometry, slit lamp biomicroscopy. We selected 58 current spherical RGP lens wearers for this three-month study. All patients exhibits at least 0.75D of corneal astigmatism measured with the keratometer, and 37 patients had corneal astigmatism of 1.50D or greater. At least follow-up visit, we measured Snellen acuity with lenses, and performed overrefraction, overkeratometry and slit lamp biomicroscopy. We charted lens position, movement and surface quality. During the three month, biomicroscopy revealed no corneal edema and neovascularization on any patients. Fluorescein staining were 52 patients case of grade 0.5 patients case of grade 1, and 1 patient case of grade 2. In evaluating post-fit residual cylinder, on overrefraction as a percentage of refractive cylinder. By the initial visit, one-week visit, one-month visit, and two-month visit are 41%, 34%, 29%, respectively. In this data, we knew no change after one month. The average overrefraction for these eyes in absolute diopters is 0.26D(initial visit), 0.22D(one-week visit, 0.17D(one-month visit), and 0.16D(two-month visit). The use of a regimen containing a dedicated daily cleaner was more effective in maintaining patient comfort and lens cleanliness than was the use of a regimen containing only a multipurpose solution.

• Clinical and Experimental Pediatrics
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• v.45 no.6
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• pp.800-803
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• 2002

A two year old male child complained of foreign body sensations bilaterally, and an itching sensation at both upper and lower eyelids for 2 months of duration. He was diagnosed with Phthiriasis palpebrarum after observation of adult louse and nits on slit-lamp examination. The treatment was accomplished by mechanical removal of the lices and nits by forceps and scissors, and then irrigation with 20% fluorescein was done under general anesthesia. Antibiotic eyedrops and ointment were applied to both eyes. The morphologic evaluation was performed with light microscopy and scanning electron microscopy. The follow-up interval was every weeks for one month and no louse or nit was found under slit-lamp examination. So we concluded that the Phthiriasis palpebrarum was eradiated completely. We report a case of Phthriasis palpebrarum had been review of the literatures.

• Journal of Korean Ophthalmic Optics Society
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• v.12 no.3
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• pp.7-17
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• 2007

There has been an increase in rigid gas permeable contact lens prescription by the optometrists in Korea since 1995. Therefore, the aim of our study was to find out which equipment is needed for adequate RGP contact lens prescription and the level of the clinical knowledge that they have and the level of education for the patient, to seize about the extended lens education programmes for the Korean optometrist. Also, we tried to figure out the problem that they had in the RGP contact lens prescription, to develope the educational programs for students and to improve legal uncertainties, through this research. The result came out with the following through questionnaires of 400 male and female opticians who is in clinical field. The distributions of respondents are 270 male (67.5%), 130 female (32.5%), and 356 optometry major (89%). We found out the optometry-majored people had faster clinical lens prescriptions (p=0.000), 72.5% of opticians prescribe the RGP-Lenses, and 27.5% do not because of laking in experience (P=0.000). They responded that they need slit-lamp, button lamp, fluorescein dry paper, and etc,for prescription or fitting test. In regular-check-up (Follow-up), the result came out very low by 83% of respondents who are not getting it regularly. And 83.5% (334 people) of them wanted to have those Extended Educational Programs and also the Clinical Education Programs.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.29-32
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• 1996

기존의 안과 진단 및 치료 기기의 안구 고정장치는 진단 및 치료에 있어서 피검사자와 검사자에 사이에 충분한 협조가 되지 않을 경우 진단의 비효율성과 치료의 안정성등의 문제가 발생하고있다. 따라서 이러한 문제를 보완하기 위하여 SLO의 전면 세극등을 소형의 반사경으로 대치하고 표시등을 후면의 먼거리에 수직으로 배열시켜서 피검사자에게 적당한 높이의 고정등을 선택하게하여 수직방향의 안구 위치를 고정시키고 SLO(Scanning Laser Ophthalmoscope)의 좌우 회전기능으로 표적의 수평방향을 근절시킨 후에 검사자의 조작으로 원격조정되는 서보장치를 이용하여 다시 반사경을 전방향으로 미세하게 회전되게하여 정확한 위치로 안구를 이동시키게 하는 원격조정 표적 추적장치를 개발하였다. 이에 따라 피검사자는 거울에 비친 먼거리의 허상을 보게 되어 세극등을 이용한 근접주사방식의 단점인 안구의 축동, 폭주등으로 인한 환자의 눈의 피로를 최소화하면서 피검사자의 안구를 검사자가 원하는 위치로 고정시킬 수 있게 함으로써 임상실험에서 안과 진단의 정확성과 관리도를 높이고 치료의 효율성과 안전성을 증가시킬 수 있는 원격조정 추적장치로써의 성능을 확인하였다.

• 전기의세계
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• v.9
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• pp.40-45
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• 1962

Laplace 및 Possion의 방정식을 만족하는 전장 및 자장으로 구성된 2차원 및 축대칭 3차원의 potential장을 물의 유동장을 이용한 fluid mapper로 상사해석함에 있어서 세극유로에 있어서의 유체전도율은 매질전도율로 압력은 전위로 유동장의 세기는 전장의 세기로, 유량밀도는 전류밀도로 각각 상사되며 또한 사상형에 있어서는 사상영역외에 존재하는 유선은 등자위선을 의미함을 논문에서 밝혔다. 이 논문에서는 사상형 fluid mapper의 전 유로 및 사상영역에 잇어서의 유체력학적 현상을 이론적으로 규명하여 이를 전기적 등가회로와 상사 해석함으로써 사상형 fluid mapper가 내포하고 있는 제량간의 상호관계를 명백히 하며 몇 가지 대표적인 사례를 들어 사상형 fluid mapper의 응용에 대하여 기술하였다.

• Journal of Korean Ophthalmic Optics Society
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• v.8 no.1
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• pp.41-45
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• 2003

The researchers have studied on the effect of three main morphological types(nuclear, cortical, and subcapsular cataract) of age related cataract on refractive error. We also identified that spherical and cylinderical shift in each type of morphological cataract accoding to their locations and effect of intraocular pressure before and after cataract surgery. Nuclear cataract showed myopic shift while cortical cataract showed hyperopic shift, and subcapsular cataract showed not significant changes on both direction. Age related cataract subjects(120 eyes) only were recruited from sun-cheon area. We use optic section of slit lamp biomicroscope to identify the anatomical location of cataract, and optimal refractive correction determined by objective(retinoscope) and subjective refraction then spherical changes were calculated from the spherical eqivalent value. Intra-ocular pressure were measured by auto-tonometer before and 7 days after cataract has been replaced by IOL. The change in cylindrical power, usually A-P diameter decreased according to increases of age, A-P diameter increased because intra-ocular pressure rises by progression of cataract and this convertion with the rule astigmatism to against the rule astigmatism and this increases more by intra-ocular pressure.

• Journal of The Korean Ophthalmological Society
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• v.60 no.5
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• pp.480-485
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• 2019

Purpose: We report a case of postoperative endophthalmitis in the cataract patient, associated with removal of an intralenticular foreign body that had remained in place without symptoms for 20 years. Case summary: A 45-year-old male visited our outpatient clinic complaining of gradual visual loss in his right eye over the past 3 months. In slit-lamp examinations, anterior capsular opacification, nuclear sclerosis, and posterior subcapsular opacity were observed in the right eye. Twenty years before, a tiny metallic projectile had hit his right eye, but slit-lamp examination at the time of injury did not reveal any intraocular foreign body. We decided to undergo cataract surgery. During phacoemulsification, a metallic foreign body was found in the lens and safely removed; then an intraocular lens was implanted. As hypopyon was evident 3 days later, we injected intravitreal antibiotics and applied fortified antibiotic eye drops to the right eye. The anterior chamber inflammation improved and the best-corrected visual acuity recovered to 1.0. Conclusions: Surgeon should be aware of that endophthalmitis could develop after cataract surgery with removal of an intralenticular foreign body that had been in place for 20 years. But did not trigger inflammation or cause any symptoms as the cataract progressed.

• The Korean Journal of Nuclear Medicine
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• v.33 no.6
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• pp.475-483
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• 1999

Purpose: Complete fibrovascular ingrowth within the hydroxyapatite ocular implant is necessary for peg drilling which is performed to Prevent infection and to provide motility to the ocular prosthesis. We compared planar bone scintigraphy and SPECT for the evaluation of the vascularization within hydroxyapatite ocular implants. Materials and Methods: Seventeen patients (M:F: 12:5, mean age; $50.4{\pm}17.5$ years) who had received a coralline hydroxyapatite ocular implant after enucleation surgery were enrolled. Patients underwent Tc-99m MDP planar bone and SPECT imaging by dual head gamma camera after their implant surgery (interval: $197{\pm}81$ days). Uptake on planar and SPECT images was graded visually as less than (grade 1), equal to (grade 2), and greater than (grade 3) nasal bridge activity. Quantitative ratio of implanted to non-implanted intraorbital activity was also measured. Vascularization within hydroxyapatite implants was confirmed by slit lamp examination and ocular movement. Results: All but three patients were considered to be vascularized within hydroxyapatite implants. In visual analysis of planar image and SPECT, grade 1 was noted in 9/18 (50%) and 6/18 (33%), respectively. Grade 2 pattern was 7/18 (39%) and 4/18 (22%), and grade 3 pattern was 2/18 (11%) and 8/18 (44%) respectively. When grade 2 or 3 was considered to be positive for vascularization, the sensitivity of planar and SPECT imaging were 60% (9/15) and 80% (12/15), respectively. In 3 patients with incomplete vascularization, both planar and SPECT showed grade 1 uptake The orbital activity ratios on planar imaging were not significantly different between complete and incomplete vascularization ($1.96{\pm}0.87$ vs $1.17{\pm}0.08$, p>0.05), however, it was significantly higher on SPECT in patients with complete vascularization ($8.44{\pm}5.45$ vs $2.20{\pm}0.87$, p<0.05). Conclusion: In the assessment of fibrovascular ingrowth within ocular implants by Tc-99m MDP bone scintigraphy, SPECT image appears to be more effective than planar scintigraphy.

• Journal of The Korean Ophthalmological Society
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• v.59 no.11
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• pp.1077-1081
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• 2018

Purpose: We report two cases of corneal edema in patients who presented with bilateral blurry vision due to vaporized amines while working in a polyurethane processing plant. Case summary: A 28-year-old male presented with bilateral blurred vision. His work involved solidifying polyurethane liquid and he often found himself exposed to polyurethane heat and gas. Purpose: We report two cases of corneal edema in patients who presented with bilateral blurry vision due to vaporized amines while working in a polyurethane processing plant. Case summary: A 28-year-old male presented with bilateral blurred vision. His work involved solidifying polyurethane liquid and he often found himself exposed to polyurethane heat and gas. On examination, the patient's uncorrected visual acuity (UCVA) was 20/40 (right) and 30/50 (left). A slit lamp examination revealed subepithelial microbullae in both eyes. The central corneal thickness (CCT) was also increased in both eyes, measuring $698{\mu}m$ (right) and $672{\mu}m$ (left). After prescribing 0.5% moxifloxacin and, 1% fluorometholone eye drops for 3 days in both eyes, the UCVA recovered to 20/40 (right) and 20/20 (left). The CCT decreased to $644{\mu}m$ (right) and $651{\mu}m$ (left), and the microbullae improved significantly in the left eye. The second patient was a 34-year-old female who presented with bilateral decreased visual acuity while at work. She worked in a factory that produced car seat filling. Her UCVA was 20/25 (right) and 20/20 (left). The CCT by specular microscopy was $537{\mu}m$ (right) and $541{\mu}m$ (left). On slit lamp examination, both eyes demonstrated bilateral central subepithelial edema. The patient did not attend any follow-up outpatient appointments after the initial presentation. Conclusions: Exposure to vaporized amines such as polyurethane may causereversible corneal toxicityeven without direct contact. Further consideration should be given to ocular safety and protection from amine compounds in the industrial field.On examination, the patient's uncorrected visual acuity (UCVA) was 20/40 (right) and 30/50 (left). A slit lamp examination revealed subepithelial microbullae in both eyes. The central corneal thickness (CCT) was also increased in both eyes, measuring $698{\mu}m$ (right) and $672{\mu}m$ (left). After prescribing 0.5% moxifloxacin and, 1% fluorometholone eye drops for 3 days in both eyes, the UCVA recovered to 20/40 (right) and 20/20 (left). The CCT decreased to $644{\mu}m$ (right) and $651{\mu}m$ (left), and the microbullae improved significantly in the left eye. The second patient was a 34-year-old female who presented with bilateral decreased visual acuity while at work. She worked in a factory that produced car seat filling. Her UCVA was 20/25 (right) and 20/20 (left). The CCT by specular microscopy was $537{\mu}m$ (right) and $541{\mu}m$ (left). On slit lamp examination, both eyes demonstrated bilateral central subepithelial edema. The patient did not attend any follow-up outpatient appointments after the initial presentation. Conclusions: Exposure to vaporized amines such as polyurethane may causereversible corneal toxicityeven without direct contact. Further consideration should be given to ocular safety and protection from amine compounds in the industrial field.