• Title/Summary/Keyword: 성대 건조

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The Voice Characteristics of Children with Palatine Tonsil and Adenoid Hypertrophy (구개편도와 아데노이드 비대 아동의 음성 특성)

  • Song, Yun-Kyung
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.8
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    • pp.790-795
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    • 2009
  • This study evaluated the voice of 68 normal children and 50 children with palatine tonsil and adenoid hypertrophy with MDVP to examine the hypothesis that their mouth breathing makes the vocal folds dry and this condition contributes to lower the level of voice quality. The results showed that children with palatine tonsil and adenoid hypertrophy had statistically significant elevations in Jitt, RAP, PPQ, Shim and APQ parameters, and had the lower level of voice quality. Therefore, the children with palatine tonsil and adenoid hypertrophy need vocal hygiene education.

Congenital Metabolic Disorders with Cutaneous Changes (피부계 이상을 동반하는 선천성대사질환)

  • Sang Eun, Lee
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.22 no.2
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    • pp.53-57
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    • 2022
  • Congenital metabolic disorders are rare inherited disorders resulting from a defect in biochemical and metabolic pathways affecting proteins, fats, carbohydrates metabolism or impaired organelle function. Depending on the abnormality of biochemical metabolism, various precursors and their abnormal metabolites can accumulate in the body and the final products which are critical in normal physiology can be deficient, resulting in disease. Congenital metabolic disorders present complicated medical conditions involving several human organ systems, including nervous system, eyes, liver, and kidneys. Various proteins and lipids are involved in the development and homeostasis of the skin, so many congenital metabolic disorders present abnormal changes in skin and hair. In this review, congenital metabolic diseases related to amino acid and lipid metabolism accompanying skin abnormalities will be discussed.

안전현장 스케치 - 자율안전과 체계적인 시스템의 완벽한 조화, (주)오리엔탈정공

  • Kim, Seong-Dae
    • The Safety technology
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    • no.192
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    • pp.24-26
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    • 2013
  • 지난 1980년 설립된 (주)오리엔탈정공은 창립 초기 단순히 철의장품 생산에만 주력했다. 하지만 조선해양분야에서 최고의 장인기업으로 우뚝 서겠다는 일념으로 사업분야를 지속적으로 확장한 결과 현재는 선박용 기계품 제작사업과 대형 상부 구조물 제작사업, 해양플랜트 특수 지원선 건조사업 등으로 업무영역을 특성화, 전문화했다. 또 (주)오리엔탈정공은 일본, 중국, 베트남 등 세계 각지에 현지 법인을 설립해 더욱 체계적이고 전문적으로 사업 다각화를 추진하고 있다. 고객과의 신뢰를 최우선으로 생각하고, 수십 년간의 건조 경험에서 축적된 기술력과 연구 개발활동을 집약한 결과였다. 여기에 더해 최근 이곳에서는 또 한 번의 도약을 준비하고 있다. 바로 철저한 안전관리를 바탕으로 재해 없는 일터를 만들기 위해 매진하고 있는 것이다. 체계적인 안전관리시스템과 자율안전관리를 통해 무재해 사업장을 조성해 나가고 있는 (주)오리엔탈정공을 찾아가 봤다.

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Development of photosensitive dielectric paste for micro-via formation (마이크로 비아 형성을 위한 감광성 유전체 페이스트의 개발)

  • Park, Seong-Dae;Yoo, Myong-Jae;Cho, Hyun-Min;Lim, Jin-Kyu;Park, Jong-Chul
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2003.05c
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    • pp.240-244
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    • 2003
  • 후막 리소그라피 기술은 기판 위에 감광성 페이스트를 도포한 후 자외선과 패턴마스크를 사용하는 광식각(photolithography) 방법을 이용하여 세부 패턴을 형성시키는 기술이다, 이 기술은 후막기술로서는 높은 해상도인 선폭 $30{\mu}m$ 이하의 미세도선을 구현할 수 있어, 후막기술을 이용한 고주파 모듈의 제조에 있어서 새로운 대안으로 주목받고 있다. 본 연구에서는 알루미나 기판 상에 수십 ${\mu}m$ 이하의 마이크로 비아를 가지는 유전체 층을 형성시킬 수 있는 저온소결용 감광성 유전체 페이스트를 개발하였다. 저온소결용 유전체 파우더와 폴리머, 모노머, 광개시제 등의 양을 조절하여 마이크로 비아를 형성할 수 있는 최적 페이스트 조성을 연구하였으며, 노광량 및 현상시간과 같은 공정변수가 마이크로 비아의 해상도에 미치는 영향을 평가하였다. 알루미나 기판에 전면 프린팅 한 후 건조, 노광, 현상, 소성 과정을 거쳐 소결전 $37{\mu}m$, 소결후 $49{\mu}m$의 해상도를 가지는 마이크로 비아를 형성할 수 있었다.

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Effects of Materials and Processing in Photosensitive Silver Pastes (감광성 실버 페이스트의 재료와 공정에 대한 영향)

  • Lee, Sang-Myoung;Park, Sung-Dae;Yoo, Myong-Jae;Lee, Woo-Sung;Nahm, Sahn
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.42-43
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    • 2006
  • LTCC 후막공정에서 일반적으로 사용되고 있는 스크린 프린팅 방법은 낮은 정밀도와 100um 이하의 선폭을 구현하는 데 한계를 보이고 있다. 이에 따라서 보다 미세한 라인을 형성 할 수 있는 반도체 미세라인 공정기술을 후막 공정에 응용한 후막 리소그라피 기술 (thick-film lithography technology)이 전자부품의 소형화에 대한 방안으로 연구 되고 있다. 본 연구에서는 후막 리소그라피 기술에 사용되는 감광성 Silver 페이스트에 영향을 미치는 각기 다른 크기와 형상의 Silver 파우더들과 인쇄 후 표면의 roughness 개선을 위한 여러 종류의 첨가제들을 첨가하여 최적의 조성을 연구 하였으며, 그린시트와 페이스트의 매칭성을 해결하기 위해서 Tg가 다른 글라스 파우더를 첨가하였다. 또한 전면 인쇄 한 후에 건조, 노광, 현상, 적층, 소성 과정을 걸치는 후막 리소그라피 기술을 이용하여 소성 후 20um이하의 선폭을 가지는 내장형 패턴 구현하였으며 투과엑스레이와 O/S 테스트 통하여 우수한 특성을 확인 할 수 있었다.

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Monitoring Hazards to Verify the Safety of Plant-Based Meat Alternatives (식물성 대체육의 안전성 검증을 위한 위해요소 모니터링)

  • Ayeong Ma;Eun Sung Shin;Seon-A Son;Tai-Sun Shin;Hyun-Jung Chung
    • Journal of Food Hygiene and Safety
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    • v.39 no.2
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    • pp.83-94
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    • 2024
  • The proportion of plant-based meat alternative (PBMA) consumers has recently increased in Korea. This is due to several reasons including protecting the environment, satisfying preferences, maintaining health, and improving eating habits. Accordingly, many companies produce and sell alternative meat using various materials. Alternative meats are classified into plant (such as soybeans and wheat), seaweed, insect, and cultured meats, depending on the raw materials used in manufacturing. PBMA is sold after undergoing processes such as grinding, seasoning, and molding. Therefore, monitoring the presence of any hazardous elements during this process is essential. Accordingly, in this study, we analyzed the harmful components of nine domestically distributed PBMA that are most easily accessible to consumers. After extracting fat from the samples and analyzing the rancidity level, samples F, G, and I were highly rancid. Trace amounts of aflatoxin were detected in samples A and B, but confirmed to be within the range. Cd and Pb were not detected in any sample. We hope that this study will help establish methods to ensure the safety of domestically sold PBMA.

Mechanical Strength and Thermal Conductivity of Silica Aerogels Opacified by Adding Oxides (산화물 첨가에 의한 불투명화 실리카 에어로겔의 기계작 강도 및 열전도도)

  • 손봉희;김계태;현상훈;성대진
    • Journal of the Korean Ceramic Society
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    • v.36 no.8
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    • pp.829-834
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    • 1999
  • The silica aerogels opacified via adding oxides were prepared by the sol-gel supercritical drying technique and their characteristics of mechanical strength and thermal conduction were investigated. The compressive strength of SiO2-10 mol% TiO2 and SiO2-10mol% Fe2O3 aerogels were 0.11 and 0.047 MP a respectively much higher than 0.025 MPa of pure silica aerogels. The thermal conductivity of silica aerogels opacified by TiO2 was as low as 0.02505 W/m${\cdot}$K at $400^{\circ}C$ It was found that the TiO2 -opacifier for improving mechanical strength and suppressing high temperature conduction of pure silica aerogels was more effective than the Fe2O3 -opacifier

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18-year Follow-up of Extended Newborn Screening for Metabolic and Endocrine Disorders (대사 및 내분비 질환에 대한 광범위 신생아 선별 검사의 18년 추적 관찰)

  • Song, Wung Joo;Lee, Sunho;Jeon, Young Mi;Kim, Sook Za;Jang, Mea Young
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.18 no.2
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    • pp.35-42
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    • 2018
  • Purpose: To follow up Korean patients with metabolic and endocrine disorders ascertained by Korea Genetics Research Center, and assess the long-term effectiveness of extended newborn screening program in Korea. Methods: From January 2000 to December 2017, tandem mass spectrometry and fluoroimmunoassay were employed in extended newborn screening (NBS). The NBS program obtained dried blood spots from 283,626 babies, 48 hours after birth, and screened for galactosemia, congenital hypothyroidism (CH), congenital adrenal hyperplasia (CAH), and 50 preventable inborn errors of amino acid, fatty acid, and organic acid metabolism. Results: 28 cases of amino acid disorders, 75 cases of organic acid disorders, 27 cases of fatty acid disorders, 51 cases of urea cycle disorders, 127 cases of CH, 14 cases of CAH, and 15 cases of galactosemia were ascertained through NBS and subsequent confirmatory laboratory tests. Patients with amino acid metabolic disorders, galactosemia, CH, or CAH were more likely to have a better long-term outcome if detected early. Early management of MSUD led to much better outcome in over 90%. Despite early intervention, 32% of other organic acidemia cases still resulted in developmental delay and neurological problems. Fatty acid disorders showed varied results; those with EMA and MCAD had a good outcome, but those with VLCAD had serious neurological problems and considerably higher mortality. 75% with UCD experienced serious neurological complications and higher mortality. Conclusion: The nation-wide NBS program must be accompanied by comprehensive long-term management and physician and family education of inborn errors of metabolism for a better outcome.

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Clinicostatistical Analysis for 53 Cases which were performed Microlaryngeal Surgery under Suspension Laryngoscope (Suspension Laryngoscope 하에 후두미세 수술을 시행한 53명에 대한 임상통계학적 고찰)

  • 전하동;최인환;추광철;김선곤
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1979.05a
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    • pp.6.3-7
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    • 1979
  • During last two. decades, microlaryngeal surgery opened now era in the laryngeal surgery. In 1960, using Lynch's suspension laryngoscope, Seal co et al performed the first successful microsurgery in the treatment of polyp and other laryngeal diseases. In 1968, Kleinsasser reported a new technique of microlaryngeal surgery with a self retaining laryngoscope. Authors studied the statistic analysis of 53 cases (75 times) of the suspension laryngoscopic microsurgery at E.N.T. department of Han Yang University Hospital from May 1972 to April 1979 an reported this result. 1) sex distribution was male 1.3 : female 1. 2) age distribution was 3rd decade 14 cases (26.4%), 2nd decade 10 cases (18.7%) and 5th decade 9 cases (17%) in order. 3) chief compliant was hoarseness 48 cases (90.6%), dyspnea 16 cases (30.5%) and sore throat 8 cases (15.1%) in order. 4) diagnostic impression was polyp 18 cases (34%), nodule 12 cases (22.6%), papilloma 9 cases (17%), tumor 7 cases (13.2%), intubation granuloma 3 cases (5.7%) in order and other kinds were laryngeal stenosis with decannulation difficulty, laryngeal paralysis and hematoma. 5) histopathologic result of 48 cases was polyp 17 cases (35.4%), papilloma 11 cases (23%), nodule 9 cases (18.9%), malignancy 3 cases (6.3%), chronic inflammation 2 cases (4.2%) in order and others were hyperkeratosis, mucous retension cyst, nodule associated abscess, granuloma, hematoma and unconfirmed case. 6) in involved site, both sides 15 cases (60%), Lt.side 5 cases (19%), Rt side 3 cases (12%), anterior commissure 3 cases (12%) on the nodule and polyp (26 cases) and whole laryngeal involvement 7 cases (63.6%), one side cord involement 3 cases (23.7%), extralaryngeal involvement 1 cases (9.1%) on the papilloma (11 cases).

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Production of a Specific Yolk Antibody against Enterotoxigenic E. coli F41 Fimbrial Antigen (장독성대장균 F41 섬모항원에 대한 특이난황항체 생산)

  • Shin, S.O.;Kim, J.W.
    • Journal of Animal Science and Technology
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    • v.44 no.5
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    • pp.633-642
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    • 2002
  • Enteric colibacillosis has economically become an important disease of young animals as a result of increasing intensification of farrowing management. The objective of this experiment is to isolate fimbrial antigen from enterotoxigenic E. coli F41, to develop specific polyclonal IgY which can effectively neutralize or reduce the proliferation of pathogens in feed or living animal system, and to apply IgY technologies to animal industry. The results obtained were as follows: The molecular weight of the purified F41 antigen was 29,500 dalton on sodium dodecyl sulfate-polyacrylamide gels. Fimbrial antigen was confirmed by the western blot method. It was observed that after immunization the level of serum antibody titer of laying hen was shown in two weeks and gradually increased. The antibody titer in egg yolk appeared two weeks after it was shown in serum antibody. The titers of egg yolk antibody were gradually increased to the maximum level of 320,000 (antigen 50${\mu}g$/$m\ell$), 450,000 (antigen 200${\mu}g$/$m\ell$), and 320,000 (antigen 600${\mu}g$/$m\ell$). According to the results of specificity test by ELISA, the anti-F41 antibodies from chicken serum and egg yolk reacted only with ETEC F41 antigen. There was no cross reaction with other ETEC strains (K88, K99, and 987P). In vitro condition, as a result of antigen binding ability of yolk antibodies, bacterial concentration was rapidly decreased to $10^5$ CFU/$m\ell$ from $10^9$ CFU/$m\ell$ when 2${\sim}$4 mg/$m\ell$ of freeze dried WSF (water soluble fraction) was added.